| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | SBI-0640756 perturbation in AsPC-1 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the SBI-0640756_AsPC-1 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| NDRG1 | N-myc downstream regulated 1 | 0.144564 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.0746487 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | 0.0730802 |
| SACK1A | scaffolding CK1 anchoring protein A | 0.0715534 |
| TLN1 | talin 1 | 0.0700338 |
| ERRFI1 | ERBB receptor feedback inhibitor 1 | 0.062348 |
| PRRC2C | proline-rich coiled-coil 2C | 0.0561813 |
| MMP1 | matrix metallopeptidase 1 | 0.0545109 |
| ENO1 | enolase 1, (alpha) | 0.0538343 |
| TPM3 | tropomyosin 3 | 0.0522129 |
| CEACAM1 | carcinoembryonic antigen-related cell adhesion molecule 1 (biliary glycoprotein) | 0.0522035 |
| ABTB2 | ankyrin repeat and BTB (POZ) domain containing 2 | 0.0519567 |
| SEMA3B | sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3B | 0.0511136 |
| MAP4K4 | mitogen-activated protein kinase kinase kinase kinase 4 | 0.0503788 |
| HIPK2 | homeodomain interacting protein kinase 2 | 0.0485929 |
| PTPN12 | protein tyrosine phosphatase, non-receptor type 12 | 0.0477718 |
| EXT1 | exostosin glycosyltransferase 1 | 0.0460742 |
| FTL | ferritin, light polypeptide | 0.04479 |
| CAP1 | CAP, adenylate cyclase-associated protein 1 (yeast) | 0.0432396 |
| TIMP1 | TIMP metallopeptidase inhibitor 1 | 0.0431494 |
| SRRM2 | serine/arginine repetitive matrix 2 | 0.0430814 |
| ABTB3 | ankyrin repeat and BTB domain containing 3 | 0.0421598 |
| CALM2 | calmodulin 2 (phosphorylase kinase, delta) | 0.0417462 |
| ZFP36L1 | ZFP36 ring finger protein-like 1 | 0.0392567 |
| ARPC1B | actin related protein 2/3 complex, subunit 1B, 41kDa | 0.0391692 |
| APLP2 | amyloid beta (A4) precursor-like protein 2 | 0.0382109 |
| EGR1 | early growth response 1 | 0.0380484 |
| AKAP9 | A kinase (PRKA) anchor protein 9 | 0.0368247 |
| BTBD9 | BTB (POZ) domain containing 9 | 0.0366135 |
| SLK | STE20-like kinase | 0.0362378 |
| PPP1R12A | protein phosphatase 1, regulatory subunit 12A | 0.0360277 |
| HNRNPDL | heterogeneous nuclear ribonucleoprotein D-like | 0.0347112 |
| B2M | beta-2-microglobulin | 0.0344696 |
| DSPP | dentin sialophosphoprotein | 0.0341507 |
| RABGEF1 | RAB guanine nucleotide exchange factor (GEF) 1 | 0.0340855 |
| RPS3 | ribosomal protein S3 | 0.0338574 |
| BRD2 | bromodomain containing 2 | 0.0338274 |
| PARD3 | par-3 family cell polarity regulator | 0.0332797 |
| HSPD1 | heat shock 60kDa protein 1 (chaperonin) | 0.0332378 |
| SEC62 | SEC62 homolog (S. cerevisiae) | 0.0330538 |
| TMSB10 | thymosin beta 10 | 0.0327115 |
| UBA6 | ubiquitin-like modifier activating enzyme 6 | 0.0317816 |
| NME7 | NME/NM23 family member 7 | 0.0306865 |
| S100A11 | S100 calcium binding protein A11 | 0.0298049 |
| RPL4 | ribosomal protein L4 | 0.0296242 |
| SMC3 | structural maintenance of chromosomes 3 | 0.0291799 |
| HLA-A | major histocompatibility complex, class I, A | 0.028306 |
| EIF1 | eukaryotic translation initiation factor 1 | 0.0282649 |
| BCAR3 | breast cancer anti-estrogen resistance 3 | 0.0281024 |
| RPL37A | ribosomal protein L37a | 0.0278746 |
| CALM1 | calmodulin 1 (phosphorylase kinase, delta) | 0.0274857 |
| GPBP1 | GC-rich promoter binding protein 1 | 0.0274348 |
| FMNL2 | formin-like 2 | 0.0268851 |
| AMPD3 | adenosine monophosphate deaminase 3 | 0.0264314 |
| TPI1 | triosephosphate isomerase 1 | 0.0262736 |
| KLK10 | kallikrein-related peptidase 10 | 0.0261491 |
| ITGA5 | integrin, alpha 5 (fibronectin receptor, alpha polypeptide) | 0.0256688 |
| DDX27 | DEAD (Asp-Glu-Ala-Asp) box polypeptide 27 | 0.0255045 |
| PTPN1 | protein tyrosine phosphatase, non-receptor type 1 | 0.0254876 |
| SEMA4B | sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4B | 0.0251818 |
| KMT2C | lysine (K)-specific methyltransferase 2C | 0.0248007 |
| BPTF | bromodomain PHD finger transcription factor | 0.0246533 |
| TAF7 | TAF7 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 55kDa | 0.0243217 |
| GUK1 | guanylate kinase 1 | 0.0243036 |
| RPL26 | ribosomal protein L26 | 0.0242909 |
| PHF20L1 | PHD finger protein 20-like 1 | 0.0240778 |
| MYL12A | myosin, light chain 12A, regulatory, non-sarcomeric | 0.0240731 |
| RBM25 | RNA binding motif protein 25 | 0.0238351 |
| AHRR | aryl-hydrocarbon receptor repressor | 0.0237818 |
| XBP1 | X-box binding protein 1 | 0.0236949 |
| PRPF6 | pre-mRNA processing factor 6 | 0.02367 |
| ANXA1 | annexin A1 | 0.0233831 |
| CCDC88A | coiled-coil domain containing 88A | 0.023181 |
| FNIP1 | folliculin interacting protein 1 | 0.0231759 |
| MAMLD1 | mastermind-like domain containing 1 | 0.0231676 |
| SERBP1 | SERPINE1 mRNA binding protein 1 | 0.0230994 |
| EEF2 | eukaryotic translation elongation factor 2 | 0.022777 |
| NAP1L1 | nucleosome assembly protein 1-like 1 | 0.0226941 |
| ARCN1 | archain 1 | 0.0226283 |
| YWHAB | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, beta | 0.0224584 |
| TRIP10 | thyroid hormone receptor interactor 10 | 0.022355 |
| AHCYL2 | adenosylhomocysteinase-like 2 | 0.0221084 |
| NUP58 | nucleoporin 58 | 0.0217788 |
| RAB31 | RAB31, member RAS oncogene family | 0.0217491 |
| S100A6 | S100 calcium binding protein A6 | 0.0214103 |
| SHOC2 | soc-2 suppressor of clear homolog (C. elegans) | 0.0210697 |
| MKRN2 | makorin ring finger protein 2 | 0.0210409 |
| ITPR3 | inositol 1,4,5-trisphosphate receptor, type 3 | 0.0210287 |
| EIF4A2 | eukaryotic translation initiation factor 4A2 | 0.0209919 |
| VSIR | V-set immunoregulatory receptor | 0.0208156 |
| HIVEP2 | human immunodeficiency virus type I enhancer binding protein 2 | 0.0207149 |
| OSBPL8 | oxysterol binding protein-like 8 | 0.0207099 |
| RASA3 | RAS p21 protein activator 3 | 0.0205474 |
| PPFIA1 | protein tyrosine phosphatase, receptor type, f polypeptide (PTPRF), interacting protein (liprin), alpha 1 | 0.0205427 |
| EIF2S2 | eukaryotic translation initiation factor 2, subunit 2 beta, 38kDa | 0.0205141 |
| ZRANB2 | zinc finger, RAN-binding domain containing 2 | 0.0204626 |
| SDC4 | syndecan 4 | 0.0201719 |
| TPCN1 | two pore segment channel 1 | 0.0199658 |
| RSU1 | Ras suppressor protein 1 | 0.0199401 |
| PPHLN1 | periphilin 1 | 0.0198953 |
| Symbol | Name | Standardized Value |
|---|---|---|
| TXNRD1 | thioredoxin reductase 1 | -0.162423 |
| SMURF1 | SMAD specific E3 ubiquitin protein ligase 1 | -0.137875 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.129525 |
| FLNB | filamin B, beta | -0.12395 |
| LMO7 | LIM domain 7 | -0.121894 |
| CD55 | CD55 molecule, decay accelerating factor for complement (Cromer blood group) | -0.117038 |
| ITGB1 | integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) | -0.110479 |
| PSD3 | pleckstrin and Sec7 domain containing 3 | -0.0991615 |
| FNDC3B | fibronectin type III domain containing 3B | -0.0900038 |
| HMGA1 | high mobility group AT-hook 1 | -0.0852468 |
| EPS8 | epidermal growth factor receptor pathway substrate 8 | -0.0828792 |
| YWHAZ | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta | -0.0797834 |
| MUC17 | mucin 17, cell surface associated | -0.0717826 |
| F3 | coagulation factor III (thromboplastin, tissue factor) | -0.0704112 |
| MYOF | myoferlin | -0.0693088 |
| EGFR | epidermal growth factor receptor | -0.0684018 |
| TRRAP | transformation/transcription domain-associated protein | -0.0662611 |
| ARPC1A | actin related protein 2/3 complex, subunit 1A, 41kDa | -0.0651583 |
| BAIAP2L1 | BAI1-associated protein 2-like 1 | -0.0642148 |
| ACTN4 | actinin, alpha 4 | -0.0639656 |
| SLC35F3 | solute carrier family 35, member F3 | -0.0639539 |
| UBE2H | ubiquitin-conjugating enzyme E2H | -0.063882 |
| GPRC5A | G protein-coupled receptor, class C, group 5, member A | -0.0623797 |
| TAOK3 | TAO kinase 3 | -0.0593907 |
| CD2AP | CD2-associated protein | -0.0577818 |
| DDX60L | DEAD (Asp-Glu-Ala-Asp) box polypeptide 60-like | -0.0567638 |
| HERC4 | HECT and RLD domain containing E3 ubiquitin protein ligase 4 | -0.0566638 |
| MAML2 | mastermind-like 2 (Drosophila) | -0.0551177 |
| RAB1A | RAB1A, member RAS oncogene family | -0.0550961 |
| CEACAM6 | carcinoembryonic antigen-related cell adhesion molecule 6 (non-specific cross reacting antigen) | -0.0520492 |
| LMTK2 | lemur tyrosine kinase 2 | -0.0517877 |
| PRSS3 | protease, serine, 3 | -0.0517068 |
| EMP1 | epithelial membrane protein 1 | -0.0511351 |
| ASPH | aspartate beta-hydroxylase | -0.0507664 |
| EFNA5 | ephrin-A5 | -0.0496297 |
| SBF2 | SET binding factor 2 | -0.0478287 |
| VCAN | versican | -0.0473247 |
| KRT8 | keratin 8, type II | -0.0466404 |
| TM4SF1 | transmembrane 4 L six family member 1 | -0.0465575 |
| PPP2R2A | protein phosphatase 2, regulatory subunit B, alpha | -0.0451092 |
| ADAM9 | ADAM metallopeptidase domain 9 | -0.0443284 |
| CAB39 | calcium binding protein 39 | -0.044149 |
| ITCH | itchy E3 ubiquitin protein ligase | -0.0441148 |
| PERP | PERP, TP53 apoptosis effector | -0.0436648 |
| FGD4 | FYVE, RhoGEF and PH domain containing 4 | -0.0434551 |
| PDLIM5 | PDZ and LIM domain 5 | -0.0434524 |
| AHNAK | AHNAK nucleoprotein | -0.0433479 |
| RICTOR | RPTOR independent companion of MTOR, complex 2 | -0.0430598 |
| VCL | vinculin | -0.0428836 |
| PTK2 | protein tyrosine kinase 2 | -0.0428103 |
| SEC31A | SEC31 homolog A (S. cerevisiae) | -0.0425655 |
| NCOA3 | nuclear receptor coactivator 3 | -0.0425405 |
| ITPRID2 | ITPR interacting domain containing 2 | -0.0424353 |
| EZR | ezrin | -0.0419968 |
| LAMA4 | laminin, alpha 4 | -0.0416323 |
| PTPRR | protein tyrosine phosphatase, receptor type, R | -0.0407028 |
| STAU1 | staufen double-stranded RNA binding protein 1 | -0.0397398 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.0394277 |
| DIAPH2 | diaphanous-related formin 2 | -0.039416 |
| MBNL1 | muscleblind-like splicing regulator 1 | -0.0391169 |
| AKAP12 | A kinase (PRKA) anchor protein 12 | -0.0388296 |
| PLEKHA1 | pleckstrin homology domain containing, family A (phosphoinositide binding specific) member 1 | -0.0385263 |
| KCMF1 | potassium channel modulatory factor 1 | -0.0384401 |
| P4HA1 | prolyl 4-hydroxylase, alpha polypeptide I | -0.0381937 |
| ARFGEF2 | ADP-ribosylation factor guanine nucleotide-exchange factor 2 (brefeldin A-inhibited) | -0.0381226 |
| HYCC2 | hyccin PI4KA lipid kinase complex subunit 2 | -0.0376795 |
| ANXA2 | annexin A2 | -0.0373942 |
| RALGPS2 | Ral GEF with PH domain and SH3 binding motif 2 | -0.037246 |
| S100A10 | S100 calcium binding protein A10 | -0.0371662 |
| INPP4B | inositol polyphosphate-4-phosphatase, type II, 105kDa | -0.0360986 |
| FOXO1 | forkhead box O1 | -0.035844 |
| ARHGAP42 | Rho GTPase activating protein 42 | -0.0357224 |
| RESF1 | retroelement silencing factor 1 | -0.0355829 |
| GCNT3 | glucosaminyl (N-acetyl) transferase 3, mucin type | -0.0355111 |
| MCL1 | myeloid cell leukemia 1 | -0.0353886 |
| RHPN2 | rhophilin, Rho GTPase binding protein 2 | -0.0348091 |
| SMAD3 | SMAD family member 3 | -0.0348038 |
| IGF2BP2 | insulin-like growth factor 2 mRNA binding protein 2 | -0.0345757 |
| KLF6 | Kruppel-like factor 6 | -0.0343736 |
| RASAL2 | RAS protein activator like 2 | -0.0342141 |
| GREB1L | growth regulation by estrogen in breast cancer-like | -0.0338533 |
| SVIL | supervillin | -0.0335765 |
| PICALM | phosphatidylinositol binding clathrin assembly protein | -0.033537 |
| DSG2 | desmoglein 2 | -0.0334632 |
| NPSR1 | neuropeptide S receptor 1 | -0.0333683 |
| ITGA2 | integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor) | -0.0331583 |
| MACF1 | microtubule-actin crosslinking factor 1 | -0.0331572 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | -0.0331227 |
| SLMAP | sarcolemma associated protein | -0.0330987 |
| MXD1 | MAX dimerization protein 1 | -0.0330757 |
| RAB22A | RAB22A, member RAS oncogene family | -0.0327193 |
| MKLN1 | muskelin 1, intracellular mediator containing kelch motifs | -0.0319845 |
| SLC5A3 | solute carrier family 5 (sodium/myo-inositol cotransporter), member 3 | -0.0317934 |
| TBC1D8 | TBC1 domain family, member 8 (with GRAM domain) | -0.0317625 |
| FGD6 | FYVE, RhoGEF and PH domain containing 6 | -0.0313651 |
| ANTXR2 | anthrax toxin receptor 2 | -0.0310219 |
| RHOA | ras homolog family member A | -0.0309789 |
| SRGAP1 | SLIT-ROBO Rho GTPase activating protein 1 | -0.03083 |
| GDA | guanine deaminase | -0.0307455 |
| EHBP1 | EH domain binding protein 1 | -0.030707 |
