| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | SBI-0640756 perturbation in C-33 A cell line (Tahoe Therapeutics) |
| Similar Terms | |
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200 genes differentially expressed following the SBI-0640756_C-33 A drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| PRRC2C | proline-rich coiled-coil 2C | 0.0349058 |
| SMYD3 | SET and MYND domain containing 3 | 0.0300015 |
| RPS3 | ribosomal protein S3 | 0.0285387 |
| INTS6 | integrator complex subunit 6 | 0.0253805 |
| RPS12 | ribosomal protein S12 | 0.0253194 |
| BRD4 | bromodomain containing 4 | 0.0247809 |
| RPL9 | ribosomal protein L9 | 0.0224958 |
| PRPF4B | pre-mRNA processing factor 4B | 0.0218928 |
| NR2F1 | nuclear receptor subfamily 2, group F, member 1 | 0.0217362 |
| SRSF4 | serine/arginine-rich splicing factor 4 | 0.021498 |
| ATF4 | activating transcription factor 4 | 0.0202423 |
| UBE2H | ubiquitin-conjugating enzyme E2H | 0.0202258 |
| UBAP2 | ubiquitin associated protein 2 | 0.0196321 |
| PTPRF | protein tyrosine phosphatase, receptor type, F | 0.0194494 |
| EIF1 | eukaryotic translation initiation factor 1 | 0.0190812 |
| KDM3B | lysine (K)-specific demethylase 3B | 0.0190606 |
| ANKRD12 | ankyrin repeat domain 12 | 0.0180822 |
| RABGEF1 | RAB guanine nucleotide exchange factor (GEF) 1 | 0.0180321 |
| OGA | O-GlcNAcase | 0.0178969 |
| PSPC1 | paraspeckle component 1 | 0.0174946 |
| MSH4 | mutS homolog 4 | 0.0171248 |
| HERPUD1 | homocysteine-inducible, endoplasmic reticulum stress-inducible, ubiquitin-like domain member 1 | 0.0170143 |
| VCL | vinculin | 0.0169832 |
| SRRM2 | serine/arginine repetitive matrix 2 | 0.0168136 |
| RBM25 | RNA binding motif protein 25 | 0.0165946 |
| RPS15A | ribosomal protein S15a | 0.016404 |
| PHF14 | PHD finger protein 14 | 0.0162621 |
| CCSAP | centriole, cilia and spindle-associated protein | 0.0158288 |
| JMJD1C | jumonji domain containing 1C | 0.0154822 |
| PABPN1 | poly(A) binding protein, nuclear 1 | 0.0151692 |
| RPL13A | ribosomal protein L13a | 0.0150469 |
| ZNF644 | zinc finger protein 644 | 0.0149972 |
| RPL4 | ribosomal protein L4 | 0.01495 |
| IGF2 | insulin-like growth factor 2 | 0.0146362 |
| TECPR2 | tectonin beta-propeller repeat containing 2 | 0.0145287 |
| KALRN | kalirin, RhoGEF kinase | 0.0142501 |
| RBBP6 | retinoblastoma binding protein 6 | 0.0140947 |
| SPOPL | speckle-type POZ protein-like | 0.0139857 |
| EPC2 | enhancer of polycomb homolog 2 (Drosophila) | 0.0139116 |
| ZC3H6 | zinc finger CCCH-type containing 6 | 0.0138792 |
| GPATCH2L | G patch domain containing 2-like | 0.0138171 |
| TPTEP2-CSNK1E | TPTEP2-CSNK1E readthrough | 0.0136913 |
| DNAJC9 | DnaJ (Hsp40) homolog, subfamily C, member 9 | 0.0136437 |
| BRWD1 | bromodomain and WD repeat domain containing 1 | 0.0135378 |
| SPECC1L | sperm antigen with calponin homology and coiled-coil domains 1-like | 0.0134988 |
| RSRP1 | arginine/serine-rich protein 1 | 0.0134751 |
| SCFD1 | sec1 family domain containing 1 | 0.013339 |
| GIGYF2 | GRB10 interacting GYF protein 2 | 0.0133137 |
| ZFYVE28 | zinc finger, FYVE domain containing 28 | 0.0131903 |
| ZNF34 | zinc finger protein 34 | 0.013123 |
| EZH2 | enhancer of zeste 2 polycomb repressive complex 2 subunit | 0.0130576 |
| ANK2 | ankyrin 2, neuronal | 0.0130234 |
| GPBP1 | GC-rich promoter binding protein 1 | 0.0129956 |
| WSB1 | WD repeat and SOCS box containing 1 | 0.0129821 |
| MSL2 | male-specific lethal 2 homolog (Drosophila) | 0.0129743 |
| UBE2D2 | ubiquitin-conjugating enzyme E2D 2 | 0.0129358 |
| KDM4B | lysine (K)-specific demethylase 4B | 0.0127996 |
| ZNF586 | zinc finger protein 586 | 0.0127896 |
| CABIN1 | calcineurin binding protein 1 | 0.0127061 |
| NCAPG2 | non-SMC condensin II complex, subunit G2 | 0.0125806 |
| TPST1 | tyrosylprotein sulfotransferase 1 | 0.012524 |
| YARS1 | tyrosyl-tRNA synthetase 1 | 0.0124847 |
| CDC42BPA | CDC42 binding protein kinase alpha (DMPK-like) | 0.012405 |
| DSCAM | Down syndrome cell adhesion molecule | 0.0123609 |
| CNOT6 | CCR4-NOT transcription complex, subunit 6 | 0.0123565 |
| HGS | hepatocyte growth factor-regulated tyrosine kinase substrate | 0.0122965 |
| GABRR2 | gamma-aminobutyric acid (GABA) A receptor, rho 2 | 0.0121895 |
| KIAA1328 | KIAA1328 | 0.0121185 |
| GARS1 | glycyl-tRNA synthetase 1 | 0.0120121 |
| DTNB | dystrobrevin, beta | 0.0119812 |
| NABP1 | nucleic acid binding protein 1 | 0.0119128 |
| MNMIP1 | manchette microtubule inner protein 1 | 0.0119094 |
| LIMA1 | LIM domain and actin binding 1 | 0.0118912 |
| SLIT2 | slit homolog 2 (Drosophila) | 0.0118689 |
| NDUFS4 | NADH dehydrogenase (ubiquinone) Fe-S protein 4, 18kDa (NADH-coenzyme Q reductase) | 0.0117703 |
| PDE7A | phosphodiesterase 7A | 0.0117444 |
| UBN2 | ubinuclein 2 | 0.0115955 |
| BBS9 | Bardet-Biedl syndrome 9 | 0.0115945 |
| SHISA5 | shisa family member 5 | 0.0115636 |
| STK38L | serine/threonine kinase 38 like | 0.0115585 |
| C3 | complement component 3 | 0.0115184 |
| ZMYND11 | zinc finger, MYND-type containing 11 | 0.0115104 |
| CLCN3 | chloride channel, voltage-sensitive 3 | 0.0114799 |
| ATF3 | activating transcription factor 3 | 0.0114326 |
| CCDC32 | coiled-coil domain containing 32 | 0.0114076 |
| TAF1D | TATA box binding protein (TBP)-associated factor, RNA polymerase I, D, 41kDa | 0.0114036 |
| IWS1 | IWS1 homolog (S. cerevisiae) | 0.0113862 |
| SFPQ | splicing factor proline/glutamine-rich | 0.0113535 |
| ZFPM2 | zinc finger protein, FOG family member 2 | 0.0113328 |
| MBOAT7 | membrane bound O-acyltransferase domain containing 7 | 0.0112974 |
| ANAPC16 | anaphase promoting complex subunit 16 | 0.0112927 |
| AXIN1 | axin 1 | 0.0111515 |
| NLRP4 | NLR family, pyrin domain containing 4 | 0.0111382 |
| PPP1R12A | protein phosphatase 1, regulatory subunit 12A | 0.011131 |
| ASNS | asparagine synthetase (glutamine-hydrolyzing) | 0.0110055 |
| CDH19 | cadherin 19, type 2 | 0.0109204 |
| PSAT1 | phosphoserine aminotransferase 1 | 0.0107791 |
| MON2 | MON2 homolog (S. cerevisiae) | 0.0107238 |
| SRF | serum response factor (c-fos serum response element-binding transcription factor) | 0.0107066 |
| MAP3K13 | mitogen-activated protein kinase kinase kinase 13 | 0.0105742 |
| Symbol | Name | Standardized Value |
|---|---|---|
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.262509 |
| TENM3 | teneurin transmembrane protein 3 | -0.151203 |
| ERBB4 | erb-b2 receptor tyrosine kinase 4 | -0.149661 |
| CTNNA2 | catenin (cadherin-associated protein), alpha 2 | -0.135909 |
| APBB2 | amyloid beta (A4) precursor protein-binding, family B, member 2 | -0.11248 |
| CTNNA3 | catenin (cadherin-associated protein), alpha 3 | -0.104989 |
| SEMA3D | sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3D | -0.101221 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | -0.0904044 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | -0.0874988 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | -0.0873791 |
| RAD51B | RAD51 paralog B | -0.0817585 |
| NPAS3 | neuronal PAS domain protein 3 | -0.0752326 |
| ACTG1 | actin gamma 1 | -0.0741713 |
| KTN1 | kinectin 1 (kinesin receptor) | -0.0700134 |
| HSPD1 | heat shock 60kDa protein 1 (chaperonin) | -0.0666405 |
| ADGRG6 | adhesion G protein-coupled receptor G6 | -0.0650286 |
| PRKDC | protein kinase, DNA-activated, catalytic polypeptide | -0.0649497 |
| LDHA | lactate dehydrogenase A | -0.0643262 |
| IMMP2L | IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) | -0.059901 |
| RAPGEF2 | Rap guanine nucleotide exchange factor (GEF) 2 | -0.0591643 |
| RPLP1 | ribosomal protein, large, P1 | -0.0587673 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | -0.0580074 |
| FMNL2 | formin-like 2 | -0.0579252 |
| CELF2 | CUGBP, Elav-like family member 2 | -0.0574967 |
| RPS6 | ribosomal protein S6 | -0.0552285 |
| RPL11 | ribosomal protein L11 | -0.0525493 |
| EIF4G2 | eukaryotic translation initiation factor 4 gamma, 2 | -0.0520575 |
| SOX4 | SRY (sex determining region Y)-box 4 | -0.051551 |
| SCD | stearoyl-CoA desaturase (delta-9-desaturase) | -0.0503983 |
| CENPF | centromere protein F, 350/400kDa | -0.0498156 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | -0.0464989 |
| TMSB10 | thymosin beta 10 | -0.0462204 |
| PDE4D | phosphodiesterase 4D, cAMP-specific | -0.0452658 |
| RAP1B | RAP1B, member of RAS oncogene family | -0.0445007 |
| TPD52 | tumor protein D52 | -0.0437768 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | -0.0435171 |
| PGK1 | phosphoglycerate kinase 1 | -0.0433682 |
| RHOA | ras homolog family member A | -0.0433041 |
| LRPPRC | leucine-rich pentatricopeptide repeat containing | -0.0431961 |
| NCOR1 | nuclear receptor corepressor 1 | -0.0426919 |
| SHROOM3 | shroom family member 3 | -0.0423869 |
| HNRNPU | heterogeneous nuclear ribonucleoprotein U (scaffold attachment factor A) | -0.0421338 |
| TOX | thymocyte selection-associated high mobility group box | -0.0416974 |
| NEBL | nebulette | -0.0413276 |
| EMP1 | epithelial membrane protein 1 | -0.0412561 |
| COL5A2 | collagen, type V, alpha 2 | -0.0409885 |
| RPS21 | ribosomal protein S21 | -0.0396118 |
| RPLP0 | ribosomal protein, large, P0 | -0.0395793 |
| PDIA3 | protein disulfide isomerase family A, member 3 | -0.0385938 |
| TOP2A | topoisomerase (DNA) II alpha 170kDa | -0.0385395 |
| RPL7A | ribosomal protein L7a | -0.0371783 |
| DNAJC5 | DnaJ (Hsp40) homolog, subfamily C, member 5 | -0.0371213 |
| CDH18 | cadherin 18, type 2 | -0.0371155 |
| PTGES3 | prostaglandin E synthase 3 (cytosolic) | -0.0370545 |
| CANX | calnexin | -0.0363285 |
| NR5A2 | nuclear receptor subfamily 5, group A, member 2 | -0.0358901 |
| DDX5 | DEAD (Asp-Glu-Ala-Asp) box helicase 5 | -0.0348025 |
| CASK | calcium/calmodulin-dependent serine protein kinase (MAGUK family) | -0.0344116 |
| RPL8 | ribosomal protein L8 | -0.0342057 |
| HMGA1 | high mobility group AT-hook 1 | -0.0341436 |
| SERBP1 | SERPINE1 mRNA binding protein 1 | -0.0341238 |
| RPS19 | ribosomal protein S19 | -0.0339889 |
| TTC3 | tetratricopeptide repeat domain 3 | -0.0339557 |
| SMARCC1 | SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily c, member 1 | -0.033488 |
| GNAS | GNAS complex locus | -0.033152 |
| ARB2A | ARB2 cotranscriptional regulator A | -0.0330676 |
| ZFP36L1 | ZFP36 ring finger protein-like 1 | -0.0325944 |
| KIAA1958 | KIAA1958 | -0.0324691 |
| TUBA1B | tubulin, alpha 1b | -0.0323275 |
| NFIA | nuclear factor I/A | -0.032211 |
| TAOK1 | TAO kinase 1 | -0.0319736 |
| EIF4A1 | eukaryotic translation initiation factor 4A1 | -0.0318084 |
| HHIP | hedgehog interacting protein | -0.0317508 |
| P4HA1 | prolyl 4-hydroxylase, alpha polypeptide I | -0.0314637 |
| TRIO | trio Rho guanine nucleotide exchange factor | -0.0311781 |
| RPS11 | ribosomal protein S11 | -0.0311658 |
| FOXO3 | forkhead box O3 | -0.0310274 |
| TUBB | tubulin, beta class I | -0.0309164 |
| LRBA | LPS-responsive vesicle trafficking, beach and anchor containing | -0.0306557 |
| DCDC2 | doublecortin domain containing 2 | -0.0305303 |
| RPL23 | ribosomal protein L23 | -0.0303731 |
| RPLP2 | ribosomal protein, large, P2 | -0.0302097 |
| GJA1 | gap junction protein, alpha 1, 43kDa | -0.0299235 |
| NF1 | neurofibromin 1 | -0.0298939 |
| B2M | beta-2-microglobulin | -0.0298617 |
| NPM1 | nucleophosmin (nucleolar phosphoprotein B23, numatrin) | -0.029373 |
| ARID2 | AT rich interactive domain 2 (ARID, RFX-like) | -0.0293659 |
| PFN1 | profilin 1 | -0.0292127 |
| WDR45B | WD repeat domain 45B | -0.0289415 |
| DEK | DEK proto-oncogene | -0.028932 |
| ATP11A | ATPase, class VI, type 11A | -0.0288321 |
| PTPRG | protein tyrosine phosphatase, receptor type, G | -0.0288122 |
| OSBPL10 | oxysterol binding protein-like 10 | -0.0287312 |
| EIF2AK2 | eukaryotic translation initiation factor 2-alpha kinase 2 | -0.0284092 |
| NRG1 | neuregulin 1 | -0.0280672 |
| KHDRBS1 | KH domain containing, RNA binding, signal transduction associated 1 | -0.0278957 |
| IFI6 | interferon, alpha-inducible protein 6 | -0.0277224 |
| HNRNPK | heterogeneous nuclear ribonucleoprotein K | -0.0276575 |
| VMP1 | vacuole membrane protein 1 | -0.0276214 |
| RPL19 | ribosomal protein L19 | -0.027582 |
