| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | SBI-0640756 perturbation in C32 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the SBI-0640756_C32 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.144537 |
| VIM | vimentin | 0.133401 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | 0.131626 |
| VGF | VGF nerve growth factor inducible | 0.131113 |
| ENO1 | enolase 1, (alpha) | 0.129719 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | 0.121454 |
| IGFBP3 | insulin-like growth factor binding protein 3 | 0.102907 |
| AKAP12 | A kinase (PRKA) anchor protein 12 | 0.0834496 |
| PTMA | prothymosin, alpha | 0.0718917 |
| EGR1 | early growth response 1 | 0.0681624 |
| LOC112694756 | uncharaterized LOC112694756 | 0.0591261 |
| B2M | beta-2-microglobulin | 0.0585794 |
| PKM | pyruvate kinase, muscle | 0.0577375 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | 0.0574925 |
| FTL | ferritin, light polypeptide | 0.05535 |
| SEM1 | SEM1 26S proteasome subunit | 0.0549663 |
| PDIA4 | protein disulfide isomerase family A, member 4 | 0.0504029 |
| RPL37A | ribosomal protein L37a | 0.0503765 |
| PRRC2C | proline-rich coiled-coil 2C | 0.0487674 |
| HLA-B | major histocompatibility complex, class I, B | 0.047242 |
| GOLGA4 | golgin A4 | 0.0459447 |
| MT2A | metallothionein 2A | 0.0457251 |
| RPS12 | ribosomal protein S12 | 0.0453109 |
| AKAP9 | A kinase (PRKA) anchor protein 9 | 0.0441435 |
| INSIG1 | insulin induced gene 1 | 0.0389095 |
| NAMPT | nicotinamide phosphoribosyltransferase | 0.0381885 |
| SRRM2 | serine/arginine repetitive matrix 2 | 0.036228 |
| TPT1 | tumor protein, translationally-controlled 1 | 0.0357186 |
| CD74 | CD74 molecule, major histocompatibility complex, class II invariant chain | 0.0343195 |
| IFI16 | interferon, gamma-inducible protein 16 | 0.0332372 |
| POLR2A | polymerase (RNA) II (DNA directed) polypeptide A, 220kDa | 0.0330408 |
| ASAP1 | ArfGAP with SH3 domain, ankyrin repeat and PH domain 1 | 0.0328102 |
| CALR | calreticulin | 0.032785 |
| CTNND1 | catenin (cadherin-associated protein), delta 1 | 0.0321772 |
| MCL1 | myeloid cell leukemia 1 | 0.0321651 |
| RPL4 | ribosomal protein L4 | 0.0316318 |
| SERPINE2 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 2 | 0.0312793 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | 0.0312061 |
| PPP1R15A | protein phosphatase 1, regulatory subunit 15A | 0.0309774 |
| APLP2 | amyloid beta (A4) precursor-like protein 2 | 0.0307333 |
| CALM1 | calmodulin 1 (phosphorylase kinase, delta) | 0.0301306 |
| TPR | translocated promoter region, nuclear basket protein | 0.0297698 |
| JMJD1C | jumonji domain containing 1C | 0.0295696 |
| LUC7L3 | LUC7-like 3 (S. cerevisiae) | 0.0293659 |
| SPTBN1 | spectrin, beta, non-erythrocytic 1 | 0.0292873 |
| TAGLN2 | transgelin 2 | 0.0292104 |
| LDHA | lactate dehydrogenase A | 0.0292087 |
| ATP1A4 | ATPase, Na+/K+ transporting, alpha 4 polypeptide | 0.0291145 |
| LGALS1 | lectin, galactoside-binding, soluble, 1 | 0.0288343 |
| RRBP1 | ribosome binding protein 1 | 0.0285868 |
| BRD2 | bromodomain containing 2 | 0.0285429 |
| IFITM3 | interferon induced transmembrane protein 3 | 0.0282802 |
| NOS1AP | nitric oxide synthase 1 (neuronal) adaptor protein | 0.0281701 |
| SEPTIN7 | septin 7 | 0.0271655 |
| EIF1 | eukaryotic translation initiation factor 1 | 0.0270341 |
| PCLO | piccolo presynaptic cytomatrix protein | 0.0270205 |
| ITGA3 | integrin, alpha 3 (antigen CD49C, alpha 3 subunit of VLA-3 receptor) | 0.0267794 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | 0.0263871 |
| ENO2 | enolase 2 (gamma, neuronal) | 0.0263681 |
| MDM2 | MDM2 proto-oncogene, E3 ubiquitin protein ligase | 0.0263333 |
| RPLP1 | ribosomal protein, large, P1 | 0.0262555 |
| WSB1 | WD repeat and SOCS box containing 1 | 0.0260468 |
| YBX1 | Y box binding protein 1 | 0.0258857 |
| SKP1 | S-phase kinase-associated protein 1 | 0.0258795 |
| IER3 | immediate early response 3 | 0.025798 |
| RBM39 | RNA binding motif protein 39 | 0.0256449 |
| ARPC1B | actin related protein 2/3 complex, subunit 1B, 41kDa | 0.0256258 |
| RPL31 | ribosomal protein L31 | 0.0251279 |
| JUN | jun proto-oncogene | 0.0250858 |
| HLA-A | major histocompatibility complex, class I, A | 0.025037 |
| TMSB10 | thymosin beta 10 | 0.0250121 |
| IGF2BP2 | insulin-like growth factor 2 mRNA binding protein 2 | 0.0249691 |
| RPL12 | ribosomal protein L12 | 0.0249502 |
| RBM33 | RNA binding motif protein 33 | 0.0246063 |
| ANXA2 | annexin A2 | 0.0245663 |
| RPS6 | ribosomal protein S6 | 0.0245385 |
| BTG1 | B-cell translocation gene 1, anti-proliferative | 0.024499 |
| CUL1 | cullin 1 | 0.0244722 |
| TNIK | TRAF2 and NCK interacting kinase | 0.024301 |
| S100A6 | S100 calcium binding protein A6 | 0.0241421 |
| RAB7A | RAB7A, member RAS oncogene family | 0.0240184 |
| BNIP3 | BCL2/adenovirus E1B 19kDa interacting protein 3 | 0.0239755 |
| TRIM9 | tripartite motif containing 9 | 0.0239507 |
| ABL2 | ABL proto-oncogene 2, non-receptor tyrosine kinase | 0.0239475 |
| IFI6 | interferon, alpha-inducible protein 6 | 0.0239252 |
| RPS3 | ribosomal protein S3 | 0.023876 |
| FUS | FUS RNA binding protein | 0.0238336 |
| MDGA2 | MAM domain containing glycosylphosphatidylinositol anchor 2 | 0.0237995 |
| MACF1 | microtubule-actin crosslinking factor 1 | 0.0237598 |
| BZW2 | basic leucine zipper and W2 domains 2 | 0.0235747 |
| P4HB | prolyl 4-hydroxylase, beta polypeptide | 0.0235644 |
| LMNA | lamin A/C | 0.0234631 |
| RPS8 | ribosomal protein S8 | 0.0234071 |
| KMT2E | lysine (K)-specific methyltransferase 2E | 0.0232615 |
| ATP5F1B | ATP synthase F1 subunit beta | 0.0232247 |
| BDP1 | B double prime 1, subunit of RNA polymerase III transcription initiation factor IIIB | 0.023151 |
| KPNB1 | karyopherin (importin) beta 1 | 0.0230784 |
| RPS19 | ribosomal protein S19 | 0.022935 |
| ABTB2 | ankyrin repeat and BTB (POZ) domain containing 2 | 0.0229012 |
| DDIT4 | DNA-damage-inducible transcript 4 | 0.0228724 |
| Symbol | Name | Standardized Value |
|---|---|---|
| FN1 | fibronectin 1 | -0.329878 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.0759703 |
| IMMP2L | IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) | -0.0725753 |
| NDRG1 | N-myc downstream regulated 1 | -0.0658811 |
| MAGI2 | membrane associated guanylate kinase, WW and PDZ domain containing 2 | -0.064131 |
| NLGN1 | neuroligin 1 | -0.0602025 |
| RUNX1 | runt-related transcription factor 1 | -0.0594647 |
| ITPR2 | inositol 1,4,5-trisphosphate receptor, type 2 | -0.0442359 |
| LEF1 | lymphoid enhancer-binding factor 1 | -0.0425412 |
| RBMS3 | RNA binding motif, single stranded interacting protein 3 | -0.0407254 |
| UBR5 | ubiquitin protein ligase E3 component n-recognin 5 | -0.0407254 |
| TRIM2 | tripartite motif containing 2 | -0.0385717 |
| ESYT2 | extended synaptotagmin-like protein 2 | -0.036554 |
| A2M | alpha-2-macroglobulin | -0.0360683 |
| GPC6 | glypican 6 | -0.0356262 |
| CHSY1 | chondroitin sulfate synthase 1 | -0.0347183 |
| OXR1 | oxidation resistance 1 | -0.0338145 |
| ITPR1 | inositol 1,4,5-trisphosphate receptor, type 1 | -0.0333145 |
| FBXL7 | F-box and leucine-rich repeat protein 7 | -0.032424 |
| PCDH7 | protocadherin 7 | -0.0316854 |
| MKLN1 | muskelin 1, intracellular mediator containing kelch motifs | -0.0315657 |
| TMTC2 | transmembrane and tetratricopeptide repeat containing 2 | -0.0315097 |
| PTK2 | protein tyrosine kinase 2 | -0.0310046 |
| PTPRJ | protein tyrosine phosphatase, receptor type, J | -0.030937 |
| TANC2 | tetratricopeptide repeat, ankyrin repeat and coiled-coil containing 2 | -0.0306938 |
| SLC5A3 | solute carrier family 5 (sodium/myo-inositol cotransporter), member 3 | -0.030181 |
| TMEM123 | transmembrane protein 123 | -0.0301101 |
| PTPN12 | protein tyrosine phosphatase, non-receptor type 12 | -0.0297617 |
| TNFRSF19 | tumor necrosis factor receptor superfamily, member 19 | -0.0288043 |
| CENPF | centromere protein F, 350/400kDa | -0.028448 |
| PRELID2 | PRELI domain containing 2 | -0.0284245 |
| CDK14 | cyclin-dependent kinase 14 | -0.0283394 |
| AHNAK | AHNAK nucleoprotein | -0.0277647 |
| FRMD4A | FERM domain containing 4A | -0.0275706 |
| TMEM178B | transmembrane protein 178B | -0.0269603 |
| NBAS | neuroblastoma amplified sequence | -0.0269346 |
| ZMYND8 | zinc finger, MYND-type containing 8 | -0.0264618 |
| CLMN | calmin (calponin-like, transmembrane) | -0.0261033 |
| GDF15 | growth differentiation factor 15 | -0.025948 |
| AHR | aryl hydrocarbon receptor | -0.0256259 |
| BPNT2 | 3'(2'), 5'-bisphosphate nucleotidase 2 | -0.0241672 |
| NAV2 | neuron navigator 2 | -0.0241374 |
| PLA2G4A | phospholipase A2, group IVA (cytosolic, calcium-dependent) | -0.0237937 |
| DIAPH2 | diaphanous-related formin 2 | -0.0237742 |
| ANO6 | anoctamin 6 | -0.0230725 |
| EGLN1 | egl-9 family hypoxia-inducible factor 1 | -0.0230051 |
| CPEB2 | cytoplasmic polyadenylation element binding protein 2 | -0.0228677 |
| MACROD2 | MACRO domain containing 2 | -0.0225662 |
| TANC1 | tetratricopeptide repeat, ankyrin repeat and coiled-coil containing 1 | -0.022488 |
| LRAT | lecithin retinol acyltransferase (phosphatidylcholine--retinol O-acyltransferase) | -0.0223473 |
| KDM2A | lysine (K)-specific demethylase 2A | -0.0218938 |
| FRMD6 | FERM domain containing 6 | -0.0218336 |
| SDC2 | syndecan 2 | -0.0217764 |
| PAFAH1B1 | platelet-activating factor acetylhydrolase 1b, regulatory subunit 1 (45kDa) | -0.0216922 |
| ATXN1 | ataxin 1 | -0.0216165 |
| MARK3 | MAP/microtubule affinity-regulating kinase 3 | -0.0214187 |
| PIAS2 | protein inhibitor of activated STAT, 2 | -0.0213725 |
| PITPNC1 | phosphatidylinositol transfer protein, cytoplasmic 1 | -0.0211738 |
| PHF21A | PHD finger protein 21A | -0.0208732 |
| NPAS2 | neuronal PAS domain protein 2 | -0.0208123 |
| VPS13B | vacuolar protein sorting 13 homolog B (yeast) | -0.0207602 |
| IL6ST | interleukin 6 signal transducer | -0.0207451 |
| CD109 | CD109 molecule | -0.0205902 |
| PDE4B | phosphodiesterase 4B, cAMP-specific | -0.0199923 |
| FOXJ3 | forkhead box J3 | -0.0198425 |
| AHCYL2 | adenosylhomocysteinase-like 2 | -0.0197889 |
| TPD52 | tumor protein D52 | -0.0194377 |
| ITGB3 | integrin, beta 3 (platelet glycoprotein IIIa, antigen CD61) | -0.0192416 |
| AKAP6 | A kinase (PRKA) anchor protein 6 | -0.0189857 |
| BCAS3 | breast carcinoma amplified sequence 3 | -0.0189422 |
| ANKRD28 | ankyrin repeat domain 28 | -0.0187753 |
| AGAP1 | ArfGAP with GTPase domain, ankyrin repeat and PH domain 1 | -0.0184804 |
| IGFBP5 | insulin-like growth factor binding protein 5 | -0.018471 |
| PHLDA1 | pleckstrin homology-like domain, family A, member 1 | -0.0183078 |
| HMCN1 | hemicentin 1 | -0.0182448 |
| GHR | growth hormone receptor | -0.0181726 |
| SMG1 | SMG1 phosphatidylinositol 3-kinase-related kinase | -0.0180916 |
| AOPEP | aminopeptidase O (putative) | -0.0178221 |
| PPFIA4 | protein tyrosine phosphatase, receptor type, f polypeptide (PTPRF), interacting protein (liprin), alpha 4 | -0.0177331 |
| FMN1 | formin 1 | -0.0176341 |
| DPYD | dihydropyrimidine dehydrogenase | -0.0175953 |
| KIF13A | kinesin family member 13A | -0.0173545 |
| DCT | dopachrome tautomerase | -0.0172603 |
| GSK3B | glycogen synthase kinase 3 beta | -0.0172602 |
| EHBP1 | EH domain binding protein 1 | -0.0171617 |
| JAZF1 | JAZF zinc finger 1 | -0.0171362 |
| OSMR | oncostatin M receptor | -0.0170913 |
| SPRED1 | sprouty-related, EVH1 domain containing 1 | -0.0170259 |
| COL19A1 | collagen, type XIX, alpha 1 | -0.0167289 |
| C10ORF90 | chromosome 10 open reading frame 90 | -0.0166152 |
| CDK19 | cyclin-dependent kinase 19 | -0.0165363 |
| CNOT2 | CCR4-NOT transcription complex, subunit 2 | -0.0164147 |
| SCFD2 | sec1 family domain containing 2 | -0.0163624 |
| DOCK7 | dedicator of cytokinesis 7 | -0.0163237 |
| PDE10A | phosphodiesterase 10A | -0.0163121 |
| PLCB1 | phospholipase C, beta 1 (phosphoinositide-specific) | -0.016214 |
| C1ORF21 | chromosome 1 open reading frame 21 | -0.016207 |
| NHSL1 | NHS-like 1 | -0.0162019 |
| CAPZA2 | capping protein (actin filament) muscle Z-line, alpha 2 | -0.0160944 |
| CTBP2 | C-terminal binding protein 2 | -0.0160877 |
