| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | SBI-0640756 perturbation in CFPAC-1 cell line (Tahoe Therapeutics) |
| Similar Terms | |
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200 genes differentially expressed following the SBI-0640756_CFPAC-1 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| IGFBP3 | insulin-like growth factor binding protein 3 | 0.136573 |
| AKAP12 | A kinase (PRKA) anchor protein 12 | 0.129031 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | 0.0936709 |
| SP100 | SP100 nuclear antigen | 0.0822226 |
| HLA-B | major histocompatibility complex, class I, B | 0.0793 |
| LAMB3 | laminin, beta 3 | 0.0659935 |
| IFI6 | interferon, alpha-inducible protein 6 | 0.0586336 |
| STC1 | stanniocalcin 1 | 0.0583292 |
| PFKFB3 | 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 3 | 0.0578377 |
| ENO1 | enolase 1, (alpha) | 0.0558634 |
| CP | ceruloplasmin (ferroxidase) | 0.054081 |
| RPL37A | ribosomal protein L37a | 0.0528596 |
| EIF1 | eukaryotic translation initiation factor 1 | 0.0526315 |
| CALM1 | calmodulin 1 (phosphorylase kinase, delta) | 0.0513959 |
| DDIT4 | DNA-damage-inducible transcript 4 | 0.0487541 |
| ARHGAP5 | Rho GTPase activating protein 5 | 0.0480887 |
| RAB7A | RAB7A, member RAS oncogene family | 0.0454299 |
| SERPINA1 | serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 1 | 0.0454155 |
| DTNA | dystrobrevin, alpha | 0.0441637 |
| RPS3 | ribosomal protein S3 | 0.0405168 |
| APOL1 | apolipoprotein L, 1 | 0.0397967 |
| STC2 | stanniocalcin 2 | 0.0366878 |
| KRT19 | keratin 19, type I | 0.035451 |
| ANGPTL4 | angiopoietin-like 4 | 0.0349298 |
| IFI27 | interferon, alpha-inducible protein 27 | 0.0348106 |
| RABGEF1 | RAB guanine nucleotide exchange factor (GEF) 1 | 0.0341373 |
| KIAA1217 | KIAA1217 | 0.0339566 |
| CALM2 | calmodulin 2 (phosphorylase kinase, delta) | 0.0337946 |
| BLZF1 | basic leucine zipper nuclear factor 1 | 0.032856 |
| IFITM1 | interferon induced transmembrane protein 1 | 0.0324728 |
| FA2H | fatty acid 2-hydroxylase | 0.0324559 |
| HLA-A | major histocompatibility complex, class I, A | 0.0323158 |
| LRRFIP1 | leucine rich repeat (in FLII) interacting protein 1 | 0.0318838 |
| IFI44L | interferon-induced protein 44-like | 0.0315341 |
| RPL4 | ribosomal protein L4 | 0.0314339 |
| PMP22 | peripheral myelin protein 22 | 0.0314031 |
| INTS6 | integrator complex subunit 6 | 0.0313744 |
| PLAT | plasminogen activator, tissue | 0.0302871 |
| ZMIZ1 | zinc finger, MIZ-type containing 1 | 0.0302683 |
| PPARD | peroxisome proliferator-activated receptor delta | 0.0300082 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | 0.0299329 |
| ABTB2 | ankyrin repeat and BTB (POZ) domain containing 2 | 0.0294176 |
| RPS12 | ribosomal protein S12 | 0.0285864 |
| ZFP36L1 | ZFP36 ring finger protein-like 1 | 0.0282569 |
| PPP1R13B | protein phosphatase 1, regulatory subunit 13B | 0.0280241 |
| THBD | thrombomodulin | 0.0277501 |
| AKAP9 | A kinase (PRKA) anchor protein 9 | 0.0274433 |
| ENO2 | enolase 2 (gamma, neuronal) | 0.0273141 |
| PTPRF | protein tyrosine phosphatase, receptor type, F | 0.0265991 |
| SEMA7A | semaphorin 7A, GPI membrane anchor (John Milton Hagen blood group) | 0.0262162 |
| CAPRIN2 | caprin family member 2 | 0.0259633 |
| ABL2 | ABL proto-oncogene 2, non-receptor tyrosine kinase | 0.0258441 |
| PKM | pyruvate kinase, muscle | 0.0253829 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.0251828 |
| EGR1 | early growth response 1 | 0.0251746 |
| SRRM2 | serine/arginine repetitive matrix 2 | 0.0249567 |
| SACK1A | scaffolding CK1 anchoring protein A | 0.024483 |
| GPATCH2L | G patch domain containing 2-like | 0.0243318 |
| VIM | vimentin | 0.0242823 |
| RPL37 | ribosomal protein L37 | 0.0241497 |
| ASPH | aspartate beta-hydroxylase | 0.0240866 |
| JUN | jun proto-oncogene | 0.024048 |
| GYS1 | glycogen synthase 1 (muscle) | 0.0235176 |
| MMP14 | matrix metallopeptidase 14 (membrane-inserted) | 0.0230195 |
| ITGB4 | integrin, beta 4 | 0.0228914 |
| NCOR2 | nuclear receptor corepressor 2 | 0.0226774 |
| BAIAP2L1 | BAI1-associated protein 2-like 1 | 0.0224809 |
| RPS27 | ribosomal protein S27 | 0.0224255 |
| ADAM8 | ADAM metallopeptidase domain 8 | 0.0215015 |
| SLCO4A1 | solute carrier organic anion transporter family, member 4A1 | 0.0212498 |
| PTMA | prothymosin, alpha | 0.0212083 |
| RPL31 | ribosomal protein L31 | 0.0210711 |
| RACK1 | receptor for activated C kinase 1 | 0.0208651 |
| CLIP1 | CAP-GLY domain containing linker protein 1 | 0.0206783 |
| BZW1 | basic leucine zipper and W2 domains 1 | 0.0205799 |
| PLXNA3 | plexin A3 | 0.0204536 |
| RPS8 | ribosomal protein S8 | 0.0203112 |
| HSPH1 | heat shock 105kDa/110kDa protein 1 | 0.0201109 |
| TIMP2 | TIMP metallopeptidase inhibitor 2 | 0.0200926 |
| EPAS1 | endothelial PAS domain protein 1 | 0.0200541 |
| SLCO1B3-SLCO1B7 | SLCO1B3-SLCO1B7 readthrough | 0.0199899 |
| OTUD5 | OTU deubiquitinase 5 | 0.0198036 |
| ISG15 | ISG15 ubiquitin-like modifier | 0.0195963 |
| ERRFI1 | ERBB receptor feedback inhibitor 1 | 0.0195258 |
| S100A11 | S100 calcium binding protein A11 | 0.0194536 |
| TMC5 | transmembrane channel-like 5 | 0.0194444 |
| MAP3K13 | mitogen-activated protein kinase kinase kinase 13 | 0.0193429 |
| ZNF638 | zinc finger protein 638 | 0.0192473 |
| ANKRD12 | ankyrin repeat domain 12 | 0.0191275 |
| ZNF511 | zinc finger protein 511 | 0.0191192 |
| HIVEP2 | human immunodeficiency virus type I enhancer binding protein 2 | 0.0191085 |
| SEC24A | SEC24 family member A | 0.019053 |
| HNRNPDL | heterogeneous nuclear ribonucleoprotein D-like | 0.0190281 |
| AFF4 | AF4/FMR2 family, member 4 | 0.0189818 |
| AHNAK2 | AHNAK nucleoprotein 2 | 0.0189549 |
| NEDD4L | neural precursor cell expressed, developmentally down-regulated 4-like, E3 ubiquitin protein ligase | 0.0188274 |
| SPSB1 | splA/ryanodine receptor domain and SOCS box containing 1 | 0.0187182 |
| HAP1 | huntingtin-associated protein 1 | 0.0183105 |
| SERPINE1 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1 | 0.0182779 |
| PPFIA1 | protein tyrosine phosphatase, receptor type, f polypeptide (PTPRF), interacting protein (liprin), alpha 1 | 0.0182761 |
| Symbol | Name | Standardized Value |
|---|---|---|
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.202758 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | -0.148463 |
| FNDC3B | fibronectin type III domain containing 3B | -0.115242 |
| SAMD4A | sterile alpha motif domain containing 4A | -0.0967595 |
| MT1X | metallothionein 1X | -0.0938997 |
| SYNE2 | spectrin repeat containing, nuclear envelope 2 | -0.0895908 |
| ARHGAP26 | Rho GTPase activating protein 26 | -0.0887528 |
| TSC22D2 | TSC22 domain family, member 2 | -0.0875137 |
| HIF1A | hypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor) | -0.0848248 |
| GPRC5A | G protein-coupled receptor, class C, group 5, member A | -0.0775698 |
| FHIP1A | FHF complex subunit HOOK interacting protein 1A | -0.076849 |
| ITGB1 | integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) | -0.0736507 |
| MYOF | myoferlin | -0.0698662 |
| EFNA5 | ephrin-A5 | -0.0671303 |
| UBC | ubiquitin C | -0.0667325 |
| APP | amyloid beta (A4) precursor protein | -0.0645664 |
| NAMPT | nicotinamide phosphoribosyltransferase | -0.0632547 |
| TMSB10 | thymosin beta 10 | -0.0612725 |
| TXNIP | thioredoxin interacting protein | -0.060867 |
| TMSB4X | thymosin beta 4, X-linked | -0.0582144 |
| RAB1A | RAB1A, member RAS oncogene family | -0.0573212 |
| P4HA1 | prolyl 4-hydroxylase, alpha polypeptide I | -0.0573146 |
| INPP4B | inositol polyphosphate-4-phosphatase, type II, 105kDa | -0.0571424 |
| POTEF | POTE ankyrin domain family, member F | -0.0563909 |
| SMAD3 | SMAD family member 3 | -0.0558903 |
| FUT8 | fucosyltransferase 8 (alpha (1,6) fucosyltransferase) | -0.0546831 |
| PTPN14 | protein tyrosine phosphatase, non-receptor type 14 | -0.0542686 |
| CD47 | CD47 molecule | -0.0542031 |
| ADAM9 | ADAM metallopeptidase domain 9 | -0.0540461 |
| TRIO | trio Rho guanine nucleotide exchange factor | -0.0539906 |
| RAD51B | RAD51 paralog B | -0.0530485 |
| TOP2A | topoisomerase (DNA) II alpha 170kDa | -0.0528632 |
| STAT1 | signal transducer and activator of transcription 1, 91kDa | -0.0524409 |
| CCNL1 | cyclin L1 | -0.0517776 |
| EHBP1 | EH domain binding protein 1 | -0.0510784 |
| CCNY | cyclin Y | -0.0506199 |
| MT2A | metallothionein 2A | -0.0500566 |
| SEMA3A | sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3A | -0.0491011 |
| MACC1 | metastasis associated in colon cancer 1 | -0.0481888 |
| MAML2 | mastermind-like 2 (Drosophila) | -0.047457 |
| PDIA3 | protein disulfide isomerase family A, member 3 | -0.0471414 |
| AHNAK | AHNAK nucleoprotein | -0.0466213 |
| NDRG1 | N-myc downstream regulated 1 | -0.0465857 |
| GPCPD1 | glycerophosphocholine phosphodiesterase GDE1 homolog (S. cerevisiae) | -0.0464747 |
| KLF6 | Kruppel-like factor 6 | -0.0444142 |
| YWHAZ | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta | -0.0438831 |
| TBL1XR1 | transducin (beta)-like 1 X-linked receptor 1 | -0.0438637 |
| OSMR | oncostatin M receptor | -0.0435824 |
| BCAT1 | branched chain amino-acid transaminase 1, cytosolic | -0.0414018 |
| ACTG1 | actin gamma 1 | -0.0411524 |
| ARRDC3 | arrestin domain containing 3 | -0.0409897 |
| RBPJ | recombination signal binding protein for immunoglobulin kappa J region | -0.0399531 |
| EPS8 | epidermal growth factor receptor pathway substrate 8 | -0.0396024 |
| NRP1 | neuropilin 1 | -0.0395703 |
| FLNB | filamin B, beta | -0.0395284 |
| CEMIP | cell migration inducing protein, hyaluronan binding | -0.0393603 |
| RTN4 | reticulon 4 | -0.0391696 |
| UGCG | UDP-glucose ceramide glucosyltransferase | -0.0391262 |
| TMEM123 | transmembrane protein 123 | -0.0389688 |
| NHS | Nance-Horan syndrome (congenital cataracts and dental anomalies) | -0.037435 |
| ALDH1A3 | aldehyde dehydrogenase 1 family, member A3 | -0.0373078 |
| FAM3C | family with sequence similarity 3, member C | -0.0370689 |
| ITGA6 | integrin, alpha 6 | -0.0370624 |
| TANC2 | tetratricopeptide repeat, ankyrin repeat and coiled-coil containing 2 | -0.03692 |
| SPTBN1 | spectrin, beta, non-erythrocytic 1 | -0.0367869 |
| KDM5B | lysine (K)-specific demethylase 5B | -0.0367273 |
| SMYD3 | SET and MYND domain containing 3 | -0.0366923 |
| SPATS2L | spermatogenesis associated, serine-rich 2-like | -0.0357012 |
| ANXA2 | annexin A2 | -0.0356012 |
| DSG2 | desmoglein 2 | -0.0347966 |
| HNRNPC | heterogeneous nuclear ribonucleoprotein C (C1/C2) | -0.0347158 |
| NPEPPS | aminopeptidase puromycin sensitive | -0.0346729 |
| TMBIM6 | transmembrane BAX inhibitor motif containing 6 | -0.0346284 |
| PARD3 | par-3 family cell polarity regulator | -0.0340733 |
| LAMA4 | laminin, alpha 4 | -0.0339172 |
| WAC | WW domain containing adaptor with coiled-coil | -0.0337022 |
| SFTPA2 | surfactant protein A2 | -0.0334113 |
| FAT1 | FAT atypical cadherin 1 | -0.0334047 |
| DHX15 | DEAH (Asp-Glu-Ala-His) box helicase 15 | -0.0332953 |
| ITGA2 | integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor) | -0.0332384 |
| NT5C2 | 5'-nucleotidase, cytosolic II | -0.033196 |
| PICALM | phosphatidylinositol binding clathrin assembly protein | -0.0331231 |
| GSK3B | glycogen synthase kinase 3 beta | -0.0330813 |
| LGALS3 | lectin, galactoside-binding, soluble, 3 | -0.0325525 |
| ANXA11 | annexin A11 | -0.0323395 |
| NRIP1 | nuclear receptor interacting protein 1 | -0.0321879 |
| KANSL1 | KAT8 regulatory NSL complex subunit 1 | -0.0321775 |
| CD2AP | CD2-associated protein | -0.0320641 |
| FAM13A | family with sequence similarity 13, member A | -0.0319714 |
| SLC12A2 | solute carrier family 12 (sodium/potassium/chloride transporter), member 2 | -0.0318927 |
| RPS23 | ribosomal protein S23 | -0.0316449 |
| NFKBIZ | nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, zeta | -0.0315962 |
| FXR1 | fragile X mental retardation, autosomal homolog 1 | -0.0315794 |
| PFKP | phosphofructokinase, platelet | -0.030966 |
| QKI | QKI, KH domain containing, RNA binding | -0.030709 |
| MYO1E | myosin IE | -0.0306308 |
| EREG | epiregulin | -0.0306051 |
| RPLP0 | ribosomal protein, large, P0 | -0.0300197 |
| CXCL8 | chemokine (C-X-C motif) ligand 8 | -0.0299439 |
| CDK6 | cyclin-dependent kinase 6 | -0.0297881 |
