| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | SBI-0640756 perturbation in HS-578T cell line (Tahoe Therapeutics) |
| Similar Terms | |
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200 genes differentially expressed following the SBI-0640756_HS-578T drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| IGFBP3 | insulin-like growth factor binding protein 3 | 0.264089 |
| TNFAIP3 | tumor necrosis factor, alpha-induced protein 3 | 0.0833869 |
| HLA-A | major histocompatibility complex, class I, A | 0.059085 |
| EGR1 | early growth response 1 | 0.0541385 |
| PPP1R15A | protein phosphatase 1, regulatory subunit 15A | 0.0481721 |
| GOLGB1 | golgin B1 | 0.0434947 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | 0.0419768 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | 0.0397625 |
| IFI6 | interferon, alpha-inducible protein 6 | 0.0396653 |
| TNFAIP8 | tumor necrosis factor, alpha-induced protein 8 | 0.0391257 |
| TIMP3 | TIMP metallopeptidase inhibitor 3 | 0.0374807 |
| ASPH | aspartate beta-hydroxylase | 0.0363701 |
| HDAC9 | histone deacetylase 9 | 0.0362016 |
| JARID2 | jumonji, AT rich interactive domain 2 | 0.0351221 |
| ENO2 | enolase 2 (gamma, neuronal) | 0.0337327 |
| HIVEP2 | human immunodeficiency virus type I enhancer binding protein 2 | 0.0331104 |
| TGFBI | transforming growth factor, beta-induced, 68kDa | 0.0329442 |
| LOC102724023 | ES1 protein homolog, mitochondrial | 0.0308287 |
| AKAP9 | A kinase (PRKA) anchor protein 9 | 0.0284728 |
| ST3GAL1 | ST3 beta-galactoside alpha-2,3-sialyltransferase 1 | 0.0266186 |
| HLA-B | major histocompatibility complex, class I, B | 0.0264908 |
| MAGI2 | membrane associated guanylate kinase, WW and PDZ domain containing 2 | 0.0249821 |
| NUCB2 | nucleobindin 2 | 0.0231959 |
| RND3 | Rho family GTPase 3 | 0.0230875 |
| PID1 | phosphotyrosine interaction domain containing 1 | 0.0230024 |
| NFE2L1 | nuclear factor, erythroid 2-like 1 | 0.0224066 |
| ATXN1 | ataxin 1 | 0.0219489 |
| IFI16 | interferon, gamma-inducible protein 16 | 0.0217869 |
| STC2 | stanniocalcin 2 | 0.0214066 |
| IFITM3 | interferon induced transmembrane protein 3 | 0.0213534 |
| PLPP3 | phospholipid phosphatase 3 | 0.0211561 |
| TLN1 | talin 1 | 0.0207432 |
| PRRC2C | proline-rich coiled-coil 2C | 0.0205617 |
| NKAIN3 | Na+/K+ transporting ATPase interacting 3 | 0.0203398 |
| BRD2 | bromodomain containing 2 | 0.0202823 |
| SERPINE2 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 2 | 0.0200866 |
| ABI3BP | ABI family, member 3 (NESH) binding protein | 0.0200633 |
| SETX | senataxin | 0.0200503 |
| NEDD4L | neural precursor cell expressed, developmentally down-regulated 4-like, E3 ubiquitin protein ligase | 0.0196456 |
| RBMS3 | RNA binding motif, single stranded interacting protein 3 | 0.0196017 |
| KCNMA1 | potassium channel, calcium activated large conductance subfamily M alpha, member 1 | 0.0195647 |
| EGFR | epidermal growth factor receptor | 0.0194879 |
| LRRC49 | leucine rich repeat containing 49 | 0.0193552 |
| ANGPTL4 | angiopoietin-like 4 | 0.0187769 |
| CDC42BPA | CDC42 binding protein kinase alpha (DMPK-like) | 0.0187125 |
| GYS1 | glycogen synthase 1 (muscle) | 0.018624 |
| STAT1 | signal transducer and activator of transcription 1, 91kDa | 0.0185882 |
| NLRP1 | NLR family, pyrin domain containing 1 | 0.0178703 |
| RPL37A | ribosomal protein L37a | 0.0173998 |
| B2M | beta-2-microglobulin | 0.0168723 |
| AFF3 | AF4/FMR2 family, member 3 | 0.0167527 |
| GBP2 | guanylate binding protein 2, interferon-inducible | 0.0165631 |
| HIVEP3 | human immunodeficiency virus type I enhancer binding protein 3 | 0.016494 |
| HERPUD1 | homocysteine-inducible, endoplasmic reticulum stress-inducible, ubiquitin-like domain member 1 | 0.0163486 |
| IFIH1 | interferon induced with helicase C domain 1 | 0.0163116 |
| TOP1 | topoisomerase (DNA) I | 0.016263 |
| WASL | Wiskott-Aldrich syndrome-like | 0.0157044 |
| ANKRD12 | ankyrin repeat domain 12 | 0.0155577 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | 0.0153942 |
| PARP14 | poly (ADP-ribose) polymerase family, member 14 | 0.0153434 |
| GPATCH8 | G patch domain containing 8 | 0.0153429 |
| PGM3 | phosphoglucomutase 3 | 0.0147777 |
| ZSWIM6 | zinc finger, SWIM-type containing 6 | 0.0145418 |
| ISG15 | ISG15 ubiquitin-like modifier | 0.0144952 |
| CREB5 | cAMP responsive element binding protein 5 | 0.0144332 |
| PDLIM5 | PDZ and LIM domain 5 | 0.0141927 |
| TMEM178B | transmembrane protein 178B | 0.0139561 |
| ABTB2 | ankyrin repeat and BTB (POZ) domain containing 2 | 0.0138468 |
| ATP2B4 | ATPase, Ca++ transporting, plasma membrane 4 | 0.0138139 |
| SLC39A11 | solute carrier family 39, member 11 | 0.0137405 |
| FGFR1 | fibroblast growth factor receptor 1 | 0.0137379 |
| ARID1A | AT rich interactive domain 1A (SWI-like) | 0.0136209 |
| PDE4D | phosphodiesterase 4D, cAMP-specific | 0.0132827 |
| ENO1 | enolase 1, (alpha) | 0.0130795 |
| COL7A1 | collagen, type VII, alpha 1 | 0.0129439 |
| LHFPL2 | lipoma HMGIC fusion partner-like 2 | 0.0128903 |
| FOXO1 | forkhead box O1 | 0.0128365 |
| ZFPM2 | zinc finger protein, FOG family member 2 | 0.0127738 |
| NEK10 | NIMA-related kinase 10 | 0.0127512 |
| PRELID2 | PRELI domain containing 2 | 0.0127433 |
| ALMS1 | Alstrom syndrome protein 1 | 0.0125758 |
| TMF1 | TATA element modulatory factor 1 | 0.012511 |
| AP3D1 | adaptor-related protein complex 3, delta 1 subunit | 0.0124537 |
| RB1CC1 | RB1-inducible coiled-coil 1 | 0.0123966 |
| ZNFX1 | zinc finger, NFX1-type containing 1 | 0.0123791 |
| NRIP1 | nuclear receptor interacting protein 1 | 0.012226 |
| RNF150 | ring finger protein 150 | 0.0120991 |
| SQSTM1 | sequestosome 1 | 0.0119232 |
| USP34 | ubiquitin specific peptidase 34 | 0.0119039 |
| WARS1 | tryptophanyl-tRNA synthetase 1 | 0.0118996 |
| SHISA5 | shisa family member 5 | 0.0118074 |
| SP100 | SP100 nuclear antigen | 0.0117847 |
| ATP2B1 | ATPase, Ca++ transporting, plasma membrane 1 | 0.0117222 |
| OAF | OAF homolog (Drosophila) | 0.011657 |
| HIVEP1 | human immunodeficiency virus type I enhancer binding protein 1 | 0.0114739 |
| IFI44L | interferon-induced protein 44-like | 0.0114406 |
| IRF1 | interferon regulatory factor 1 | 0.0113971 |
| C1R | complement component 1, r subcomponent | 0.0113874 |
| KDM6B | lysine (K)-specific demethylase 6B | 0.0113819 |
| ANO10 | anoctamin 10 | 0.0113751 |
| Symbol | Name | Standardized Value |
|---|---|---|
| FN1 | fibronectin 1 | -0.405734 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.274437 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.260116 |
| COL1A1 | collagen, type I, alpha 1 | -0.132508 |
| TRIO | trio Rho guanine nucleotide exchange factor | -0.130901 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | -0.107608 |
| VIM | vimentin | -0.104599 |
| MT2A | metallothionein 2A | -0.0928157 |
| COL1A2 | collagen, type I, alpha 2 | -0.0906471 |
| COL6A3 | collagen, type VI, alpha 3 | -0.0899266 |
| ATP13A3 | ATPase type 13A3 | -0.088614 |
| SPARC | secreted protein, acidic, cysteine-rich (osteonectin) | -0.0876836 |
| CXCL8 | chemokine (C-X-C motif) ligand 8 | -0.0841119 |
| YWHAZ | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta | -0.0817573 |
| TM4SF1 | transmembrane 4 L six family member 1 | -0.0707259 |
| TMSB10 | thymosin beta 10 | -0.0703982 |
| PTK2 | protein tyrosine kinase 2 | -0.0650707 |
| POSTN | periostin, osteoblast specific factor | -0.0631071 |
| SPOCK1 | sparc/osteonectin, cwcv and kazal-like domains proteoglycan (testican) 1 | -0.0602386 |
| IER3 | immediate early response 3 | -0.0560746 |
| ANXA2 | annexin A2 | -0.0533955 |
| RPL8 | ribosomal protein L8 | -0.0530083 |
| SPAG9 | sperm associated antigen 9 | -0.0526794 |
| CANX | calnexin | -0.0523986 |
| ACTG1 | actin gamma 1 | -0.050923 |
| PDE10A | phosphodiesterase 10A | -0.0502897 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | -0.0485932 |
| AHNAK | AHNAK nucleoprotein | -0.0482443 |
| CD44 | CD44 molecule (Indian blood group) | -0.048007 |
| TPM4 | tropomyosin 4 | -0.0469458 |
| RAB1A | RAB1A, member RAS oncogene family | -0.0465677 |
| LOXL2 | lysyl oxidase-like 2 | -0.0461308 |
| ZNF292 | zinc finger protein 292 | -0.0461148 |
| GNB1 | guanine nucleotide binding protein (G protein), beta polypeptide 1 | -0.0452547 |
| CALU | calumenin | -0.0448964 |
| WASF2 | WAS protein family, member 2 | -0.0446892 |
| MT1X | metallothionein 1X | -0.0430021 |
| LPP | LIM domain containing preferred translocation partner in lipoma | -0.0424608 |
| ZFAND3 | zinc finger, AN1-type domain 3 | -0.0423333 |
| UBC | ubiquitin C | -0.042098 |
| NAMPT | nicotinamide phosphoribosyltransferase | -0.0412634 |
| HMGA2 | high mobility group AT-hook 2 | -0.0401815 |
| CAVIN1 | caveolae associated protein 1 | -0.0400652 |
| RPL35A | ribosomal protein L35a | -0.0390498 |
| S100A9 | S100 calcium binding protein A9 | -0.0379971 |
| LOX | lysyl oxidase | -0.0377728 |
| TFG | TRK-fused gene | -0.0376935 |
| RPL23 | ribosomal protein L23 | -0.0364744 |
| PRRC1 | proline-rich coiled-coil 1 | -0.0363167 |
| RPS8 | ribosomal protein S8 | -0.0362509 |
| SLC5A3 | solute carrier family 5 (sodium/myo-inositol cotransporter), member 3 | -0.0361637 |
| QKI | QKI, KH domain containing, RNA binding | -0.036031 |
| MRTFA | myocardin related transcription factor A | -0.0355724 |
| CDH13 | cadherin 13 | -0.035036 |
| LGALS1 | lectin, galactoside-binding, soluble, 1 | -0.0343122 |
| USP3 | ubiquitin specific peptidase 3 | -0.0342187 |
| COL3A1 | collagen, type III, alpha 1 | -0.0338281 |
| SQLE | squalene epoxidase | -0.0336072 |
| LDHA | lactate dehydrogenase A | -0.0333503 |
| DSTN | destrin (actin depolymerizing factor) | -0.0332614 |
| TMSB4X | thymosin beta 4, X-linked | -0.0330713 |
| CSDE1 | cold shock domain containing E1, RNA-binding | -0.0328007 |
| TFPI | tissue factor pathway inhibitor (lipoprotein-associated coagulation inhibitor) | -0.0327432 |
| RPL11 | ribosomal protein L11 | -0.0325341 |
| UBR5 | ubiquitin protein ligase E3 component n-recognin 5 | -0.0317815 |
| P4HA2 | prolyl 4-hydroxylase, alpha polypeptide II | -0.0317644 |
| MARCHF6 | membrane associated ring-CH-type finger 6 | -0.0313667 |
| MAP4 | microtubule-associated protein 4 | -0.0312641 |
| SMAD3 | SMAD family member 3 | -0.0308616 |
| RHEB | Ras homolog enriched in brain | -0.0308065 |
| RPL28 | ribosomal protein L28 | -0.0307347 |
| ANKRD11 | ankyrin repeat domain 11 | -0.0304864 |
| RAD21 | RAD21 homolog (S. pombe) | -0.0302947 |
| RICTOR | RPTOR independent companion of MTOR, complex 2 | -0.0302111 |
| PRKDC | protein kinase, DNA-activated, catalytic polypeptide | -0.0299672 |
| EEF2 | eukaryotic translation elongation factor 2 | -0.0298928 |
| ELL2 | elongation factor, RNA polymerase II, 2 | -0.0296607 |
| KHDRBS1 | KH domain containing, RNA binding, signal transduction associated 1 | -0.0294893 |
| GNAI3 | guanine nucleotide binding protein (G protein), alpha inhibiting activity polypeptide 3 | -0.0294078 |
| ALCAM | activated leukocyte cell adhesion molecule | -0.0288665 |
| RHOA | ras homolog family member A | -0.02849 |
| TPM2 | tropomyosin 2 (beta) | -0.0284064 |
| FMNL2 | formin-like 2 | -0.0280317 |
| YWHAQ | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, theta | -0.0278776 |
| FXR1 | fragile X mental retardation, autosomal homolog 1 | -0.0276582 |
| GRB10 | growth factor receptor-bound protein 10 | -0.0275871 |
| TUBA1B | tubulin, alpha 1b | -0.0274406 |
| ICAM1 | intercellular adhesion molecule 1 | -0.027371 |
| CTNNA1 | catenin (cadherin-associated protein), alpha 1, 102kDa | -0.0271836 |
| RPL19 | ribosomal protein L19 | -0.0271569 |
| SBF2 | SET binding factor 2 | -0.027144 |
| RPL7 | ribosomal protein L7 | -0.0269611 |
| HILPDA | hypoxia inducible lipid droplet-associated | -0.0269358 |
| NPEPPS | aminopeptidase puromycin sensitive | -0.0268472 |
| PPP2R2A | protein phosphatase 2, regulatory subunit B, alpha | -0.0266698 |
| NPM1 | nucleophosmin (nucleolar phosphoprotein B23, numatrin) | -0.0266549 |
| SEPTIN7 | septin 7 | -0.0266047 |
| ITGA5 | integrin, alpha 5 (fibronectin receptor, alpha polypeptide) | -0.0265721 |
| LOC112694756 | uncharaterized LOC112694756 | -0.0265442 |
| HYCC1 | hyccin PI4KA lipid kinase complex subunit 1 | -0.0264513 |
