| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | SBI-0640756 perturbation in LOX-IMVI cell line (Tahoe Therapeutics) |
| Similar Terms | |
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200 genes differentially expressed following the SBI-0640756_LOX-IMVI drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| HDAC9 | histone deacetylase 9 | 0.10017 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.0737825 |
| RPS12 | ribosomal protein S12 | 0.0660407 |
| PPP1R15A | protein phosphatase 1, regulatory subunit 15A | 0.0659805 |
| DTNA | dystrobrevin, alpha | 0.0624602 |
| RPS3 | ribosomal protein S3 | 0.0609552 |
| FTL | ferritin, light polypeptide | 0.0608313 |
| MCTP1 | multiple C2 domains, transmembrane 1 | 0.0603517 |
| ENO2 | enolase 2 (gamma, neuronal) | 0.0594341 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | 0.0547256 |
| SLC2A3 | solute carrier family 2 (facilitated glucose transporter), member 3 | 0.0522848 |
| CREB5 | cAMP responsive element binding protein 5 | 0.0505854 |
| GPHN | gephyrin | 0.0488458 |
| INTS6 | integrator complex subunit 6 | 0.0482823 |
| ADAM32 | ADAM metallopeptidase domain 32 | 0.0460198 |
| ABL2 | ABL proto-oncogene 2, non-receptor tyrosine kinase | 0.0456138 |
| RPL4 | ribosomal protein L4 | 0.0413519 |
| ZSWIM6 | zinc finger, SWIM-type containing 6 | 0.0405119 |
| RPS2 | ribosomal protein S2 | 0.0400075 |
| CXCL8 | chemokine (C-X-C motif) ligand 8 | 0.0389514 |
| SP100 | SP100 nuclear antigen | 0.0384794 |
| NEDD4L | neural precursor cell expressed, developmentally down-regulated 4-like, E3 ubiquitin protein ligase | 0.0384028 |
| TLN1 | talin 1 | 0.0357515 |
| EGR1 | early growth response 1 | 0.0357025 |
| SRRM2 | serine/arginine repetitive matrix 2 | 0.0353052 |
| TXNRD1 | thioredoxin reductase 1 | 0.0347914 |
| ITSN2 | intersectin 2 | 0.0337154 |
| PFKFB3 | 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 3 | 0.0327655 |
| ARFGEF3 | ARFGEF family member 3 | 0.0310991 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | 0.0310885 |
| NUP58 | nucleoporin 58 | 0.0303104 |
| FAT1 | FAT atypical cadherin 1 | 0.0301386 |
| HIVEP2 | human immunodeficiency virus type I enhancer binding protein 2 | 0.0297769 |
| DSCAM | Down syndrome cell adhesion molecule | 0.0291033 |
| NGLY1 | N-glycanase 1 | 0.0282329 |
| ASPH | aspartate beta-hydroxylase | 0.0281375 |
| KDM3A | lysine (K)-specific demethylase 3A | 0.0278824 |
| STC1 | stanniocalcin 1 | 0.0275462 |
| BRD2 | bromodomain containing 2 | 0.0266452 |
| GPC5 | glypican 5 | 0.0263748 |
| FAM162A | family with sequence similarity 162, member A | 0.0261571 |
| PRRC2C | proline-rich coiled-coil 2C | 0.0252197 |
| NR4A3 | nuclear receptor subfamily 4, group A, member 3 | 0.0249133 |
| MARCHF4 | membrane associated ring-CH-type finger 4 | 0.0242777 |
| CRIM1 | cysteine rich transmembrane BMP regulator 1 (chordin-like) | 0.0237691 |
| ENO1 | enolase 1, (alpha) | 0.023416 |
| EEF2 | eukaryotic translation elongation factor 2 | 0.023163 |
| CCDC50 | coiled-coil domain containing 50 | 0.0227569 |
| KDM6B | lysine (K)-specific demethylase 6B | 0.0223745 |
| MALT1 | MALT1 paracaspase | 0.0221841 |
| DCBLD2 | discoidin, CUB and LCCL domain containing 2 | 0.0220114 |
| LIMA1 | LIM domain and actin binding 1 | 0.0217121 |
| CD163L1 | CD163 molecule-like 1 | 0.0217054 |
| NEK10 | NIMA-related kinase 10 | 0.0215785 |
| EIF5B | eukaryotic translation initiation factor 5B | 0.0213633 |
| RPL37A | ribosomal protein L37a | 0.0210725 |
| GADD45A | growth arrest and DNA-damage-inducible, alpha | 0.0209925 |
| ANO6 | anoctamin 6 | 0.0208522 |
| LRP6 | low density lipoprotein receptor-related protein 6 | 0.020805 |
| PRRC2A | proline-rich coiled-coil 2A | 0.0206349 |
| SLC25A5 | solute carrier family 25 (mitochondrial carrier; adenine nucleotide translocator), member 5 | 0.020484 |
| EIF1 | eukaryotic translation initiation factor 1 | 0.0204256 |
| CEP350 | centrosomal protein 350kDa | 0.0203602 |
| FOXO3 | forkhead box O3 | 0.020254 |
| ERC1 | ELKS/RAB6-interacting/CAST family member 1 | 0.0201653 |
| RSRC2 | arginine/serine-rich coiled-coil 2 | 0.0201229 |
| STARD13 | StAR-related lipid transfer (START) domain containing 13 | 0.0200592 |
| SON | SON DNA binding protein | 0.0199373 |
| RPL35A | ribosomal protein L35a | 0.0198729 |
| NBEA | neurobeachin | 0.0198177 |
| ETS1 | v-ets avian erythroblastosis virus E26 oncogene homolog 1 | 0.0196125 |
| ATF3 | activating transcription factor 3 | 0.0194255 |
| EIF4A1 | eukaryotic translation initiation factor 4A1 | 0.0190355 |
| TTC3 | tetratricopeptide repeat domain 3 | 0.0189796 |
| BRWD1 | bromodomain and WD repeat domain containing 1 | 0.0189768 |
| RACK1 | receptor for activated C kinase 1 | 0.018887 |
| GOLGB1 | golgin B1 | 0.0187726 |
| IMMT | inner membrane protein, mitochondrial | 0.0187495 |
| WWTR1 | WW domain containing transcription regulator 1 | 0.0187006 |
| DIAPH1 | diaphanous-related formin 1 | 0.0186532 |
| TTC27 | tetratricopeptide repeat domain 27 | 0.0184382 |
| GLS2 | glutaminase 2 (liver, mitochondrial) | 0.018195 |
| DUSP6 | dual specificity phosphatase 6 | 0.0181585 |
| SNX14 | sorting nexin 14 | 0.0180709 |
| BHLHE40 | basic helix-loop-helix family, member e40 | 0.0180306 |
| BIRC3 | baculoviral IAP repeat containing 3 | 0.018005 |
| ANK3 | ankyrin 3, node of Ranvier (ankyrin G) | 0.0179043 |
| KIAA1958 | KIAA1958 | 0.0178902 |
| TEX14 | testis expressed 14 | 0.0178526 |
| WNT2B | wingless-type MMTV integration site family, member 2B | 0.0175155 |
| PTPRM | protein tyrosine phosphatase, receptor type, M | 0.0174877 |
| TMEM14B | transmembrane protein 14B | 0.0172756 |
| GLG1 | golgi glycoprotein 1 | 0.0172002 |
| ACVR1C | activin A receptor, type IC | 0.017094 |
| EIF4B | eukaryotic translation initiation factor 4B | 0.0169619 |
| IRS2 | insulin receptor substrate 2 | 0.0169296 |
| TFRC | transferrin receptor | 0.0169039 |
| BAZ1A | bromodomain adjacent to zinc finger domain, 1A | 0.016884 |
| PSEN1 | presenilin 1 | 0.0168222 |
| UBXN4 | UBX domain protein 4 | 0.0168058 |
| Symbol | Name | Standardized Value |
|---|---|---|
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.389345 |
| AKAP12 | A kinase (PRKA) anchor protein 12 | -0.233933 |
| VIM | vimentin | -0.164249 |
| SLC8A1 | solute carrier family 8 (sodium/calcium exchanger), member 1 | -0.136986 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.133097 |
| PLEKHA5 | pleckstrin homology domain containing, family A member 5 | -0.101242 |
| AHNAK | AHNAK nucleoprotein | -0.100872 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.100315 |
| MMP12 | matrix metallopeptidase 12 | -0.0900671 |
| CDH13 | cadherin 13 | -0.079522 |
| FN1 | fibronectin 1 | -0.077503 |
| PBX3 | pre-B-cell leukemia homeobox 3 | -0.0755673 |
| ANXA2 | annexin A2 | -0.0707425 |
| LIMS1 | LIM and senescent cell antigen-like domains 1 | -0.0677598 |
| NALF1 | NALCN channel auxiliary factor 1 | -0.0644473 |
| PRKG1 | protein kinase, cGMP-dependent, type I | -0.0637466 |
| FNDC3B | fibronectin type III domain containing 3B | -0.0633901 |
| GPC6 | glypican 6 | -0.0618123 |
| KCNQ5 | potassium channel, voltage gated KQT-like subfamily Q, member 5 | -0.0607088 |
| KIAA1549L | KIAA1549-like | -0.0602968 |
| UBR5 | ubiquitin protein ligase E3 component n-recognin 5 | -0.0589746 |
| PHACTR1 | phosphatase and actin regulator 1 | -0.0570461 |
| PTMA | prothymosin, alpha | -0.0540771 |
| RPS6 | ribosomal protein S6 | -0.0516773 |
| SAMD3 | sterile alpha motif domain containing 3 | -0.0499027 |
| IMMP2L | IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) | -0.0498729 |
| PTCHD4 | patched domain containing 4 | -0.0491841 |
| YWHAZ | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta | -0.0486532 |
| TMSB10 | thymosin beta 10 | -0.0482207 |
| NTM | neurotrimin | -0.0478279 |
| CDK6 | cyclin-dependent kinase 6 | -0.0473167 |
| NAV1 | neuron navigator 1 | -0.0472147 |
| TPM4 | tropomyosin 4 | -0.0471102 |
| PTK2 | protein tyrosine kinase 2 | -0.0465915 |
| CD44 | CD44 molecule (Indian blood group) | -0.0464004 |
| APBB2 | amyloid beta (A4) precursor protein-binding, family B, member 2 | -0.0451291 |
| IGF2BP2 | insulin-like growth factor 2 mRNA binding protein 2 | -0.0450874 |
| CD109 | CD109 molecule | -0.0448788 |
| FOXP1 | forkhead box P1 | -0.0448382 |
| MAP4 | microtubule-associated protein 4 | -0.0436551 |
| RPS24 | ribosomal protein S24 | -0.0436151 |
| CTSB | cathepsin B | -0.0429731 |
| VCL | vinculin | -0.0427157 |
| EPB41L2 | erythrocyte membrane protein band 4.1-like 2 | -0.0420556 |
| RPL7 | ribosomal protein L7 | -0.0419694 |
| RPLP1 | ribosomal protein, large, P1 | -0.0414728 |
| ALCAM | activated leukocyte cell adhesion molecule | -0.0404934 |
| SBF2 | SET binding factor 2 | -0.0404407 |
| SERPINE1 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1 | -0.0400462 |
| CANX | calnexin | -0.0400357 |
| SIPA1L3 | signal-induced proliferation-associated 1 like 3 | -0.0393567 |
| RBMS1 | RNA binding motif, single stranded interacting protein 1 | -0.0392584 |
| RPS8 | ribosomal protein S8 | -0.0392045 |
| HMGA1 | high mobility group AT-hook 1 | -0.0380359 |
| MAP3K20 | mitogen-activated protein kinase kinase kinase 20 | -0.0379755 |
| KCNMA1 | potassium channel, calcium activated large conductance subfamily M alpha, member 1 | -0.0374256 |
| RTN4 | reticulon 4 | -0.0374245 |
| RPL8 | ribosomal protein L8 | -0.0369641 |
| GNAQ | guanine nucleotide binding protein (G protein), q polypeptide | -0.0366011 |
| PDE4D | phosphodiesterase 4D, cAMP-specific | -0.0363782 |
| BRIP1 | BRCA1 interacting protein C-terminal helicase 1 | -0.0352692 |
| HAS2 | hyaluronan synthase 2 | -0.0348157 |
| RAB1A | RAB1A, member RAS oncogene family | -0.0348061 |
| RAI14 | retinoic acid induced 14 | -0.0346797 |
| KYNU | kynureninase | -0.0345442 |
| MAML2 | mastermind-like 2 (Drosophila) | -0.0341631 |
| SSH2 | slingshot protein phosphatase 2 | -0.0338105 |
| PTPRG | protein tyrosine phosphatase, receptor type, G | -0.0337432 |
| BMPR2 | bone morphogenetic protein receptor, type II (serine/threonine kinase) | -0.0337327 |
| PGK1 | phosphoglycerate kinase 1 | -0.0331943 |
| CAVIN1 | caveolae associated protein 1 | -0.032758 |
| KLF7 | Kruppel-like factor 7 (ubiquitous) | -0.0321839 |
| NRP2 | neuropilin 2 | -0.0321355 |
| NLGN1 | neuroligin 1 | -0.0317594 |
| ERBIN | erbb2 interacting protein | -0.0316366 |
| CDK17 | cyclin-dependent kinase 17 | -0.0314604 |
| SDCCAG8 | serologically defined colon cancer antigen 8 | -0.0313365 |
| NSD2 | nuclear receptor binding SET domain protein 2 | -0.0311007 |
| ITGB1 | integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) | -0.0308779 |
| MARCKS | myristoylated alanine-rich protein kinase C substrate | -0.0308297 |
| SRGAP1 | SLIT-ROBO Rho GTPase activating protein 1 | -0.0301845 |
| RPS25 | ribosomal protein S25 | -0.0301491 |
| TMEM123 | transmembrane protein 123 | -0.0298185 |
| ADAM19 | ADAM metallopeptidase domain 19 | -0.0294879 |
| MDM2 | MDM2 proto-oncogene, E3 ubiquitin protein ligase | -0.0293341 |
| PICALM | phosphatidylinositol binding clathrin assembly protein | -0.0293028 |
| RPL36A | ribosomal protein L36a | -0.0291797 |
| TBL1XR1 | transducin (beta)-like 1 X-linked receptor 1 | -0.0288919 |
| MBNL1 | muscleblind-like splicing regulator 1 | -0.0284001 |
| ACTR2 | ARP2 actin-related protein 2 homolog (yeast) | -0.0282562 |
| SENP6 | SUMO1/sentrin specific peptidase 6 | -0.0281037 |
| AGAP1 | ArfGAP with GTPase domain, ankyrin repeat and PH domain 1 | -0.0279287 |
| IFI16 | interferon, gamma-inducible protein 16 | -0.0269461 |
| COL6A1 | collagen, type VI, alpha 1 | -0.0269334 |
| DOCK4 | dedicator of cytokinesis 4 | -0.0267678 |
| SCRN1 | secernin 1 | -0.0267231 |
| EMP1 | epithelial membrane protein 1 | -0.0265795 |
| NRP1 | neuropilin 1 | -0.0265443 |
| HSPD1 | heat shock 60kDa protein 1 (chaperonin) | -0.0264517 |
| MSN | moesin | -0.0263728 |
