| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | SBI-0640756 perturbation in NCI-H1792 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the SBI-0640756_NCI-H1792 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| AKAP12 | A kinase (PRKA) anchor protein 12 | 0.0935897 |
| MT2A | metallothionein 2A | 0.0777386 |
| FTL | ferritin, light polypeptide | 0.0580698 |
| PTPN12 | protein tyrosine phosphatase, non-receptor type 12 | 0.0472779 |
| TIMP1 | TIMP metallopeptidase inhibitor 1 | 0.0429769 |
| SERPINE1 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1 | 0.0404846 |
| B2M | beta-2-microglobulin | 0.0398054 |
| NTN4 | netrin 4 | 0.0397475 |
| EIF1 | eukaryotic translation initiation factor 1 | 0.0382739 |
| CD44 | CD44 molecule (Indian blood group) | 0.0350869 |
| STC1 | stanniocalcin 1 | 0.0349142 |
| PITPNC1 | phosphatidylinositol transfer protein, cytoplasmic 1 | 0.0344615 |
| RPL4 | ribosomal protein L4 | 0.0337129 |
| ANGPTL4 | angiopoietin-like 4 | 0.0336489 |
| TMSB10 | thymosin beta 10 | 0.033626 |
| PRRC2C | proline-rich coiled-coil 2C | 0.0306606 |
| MAP4K4 | mitogen-activated protein kinase kinase kinase kinase 4 | 0.0304885 |
| TGM2 | transglutaminase 2 | 0.0299338 |
| RPS6KA3 | ribosomal protein S6 kinase, 90kDa, polypeptide 3 | 0.0278591 |
| EGR1 | early growth response 1 | 0.0272326 |
| VIM | vimentin | 0.0269769 |
| HLA-B | major histocompatibility complex, class I, B | 0.0258008 |
| ZFP36L1 | ZFP36 ring finger protein-like 1 | 0.0247287 |
| RPS3 | ribosomal protein S3 | 0.024266 |
| WSB1 | WD repeat and SOCS box containing 1 | 0.0242479 |
| PLAUR | plasminogen activator, urokinase receptor | 0.0240191 |
| ARHGAP5 | Rho GTPase activating protein 5 | 0.0235719 |
| RPL37A | ribosomal protein L37a | 0.023509 |
| BASP1 | brain abundant, membrane attached signal protein 1 | 0.0234062 |
| RPL36 | ribosomal protein L36 | 0.0227531 |
| YBX3 | Y box binding protein 3 | 0.0224066 |
| RAB27B | RAB27B, member RAS oncogene family | 0.0215241 |
| RPS12 | ribosomal protein S12 | 0.0214915 |
| ADM | adrenomedullin | 0.021336 |
| IFI6 | interferon, alpha-inducible protein 6 | 0.021125 |
| RFFL | ring finger and FYVE-like domain containing E3 ubiquitin protein ligase | 0.0210431 |
| SPRED2 | sprouty-related, EVH1 domain containing 2 | 0.0209877 |
| POLD4 | polymerase (DNA-directed), delta 4, accessory subunit | 0.019902 |
| FTH1 | ferritin, heavy polypeptide 1 | 0.0197785 |
| ENO2 | enolase 2 (gamma, neuronal) | 0.0195342 |
| SIK3 | SIK family kinase 3 | 0.0193865 |
| USP47 | ubiquitin specific peptidase 47 | 0.0184636 |
| THBD | thrombomodulin | 0.0184541 |
| ICAM1 | intercellular adhesion molecule 1 | 0.0182366 |
| DCBLD2 | discoidin, CUB and LCCL domain containing 2 | 0.0181791 |
| HLA-A | major histocompatibility complex, class I, A | 0.0178163 |
| RPS18 | ribosomal protein S18 | 0.0177862 |
| AMPD3 | adenosine monophosphate deaminase 3 | 0.0177437 |
| RPS19 | ribosomal protein S19 | 0.0174793 |
| PLAT | plasminogen activator, tissue | 0.0174775 |
| HAS2 | hyaluronan synthase 2 | 0.0173154 |
| ARID3B | AT rich interactive domain 3B (BRIGHT-like) | 0.0171713 |
| GLCCI1 | glucocorticoid induced 1 | 0.01712 |
| RASSF8 | Ras association (RalGDS/AF-6) domain family (N-terminal) member 8 | 0.0168742 |
| LUZP1 | leucine zipper protein 1 | 0.016743 |
| DAB2 | Dab, mitogen-responsive phosphoprotein, homolog 2 (Drosophila) | 0.0165998 |
| AKAP13 | A kinase (PRKA) anchor protein 13 | 0.0164218 |
| PPP1R15A | protein phosphatase 1, regulatory subunit 15A | 0.0162014 |
| IFITM3 | interferon induced transmembrane protein 3 | 0.0159863 |
| MAST4 | microtubule associated serine/threonine kinase family member 4 | 0.0158595 |
| RPL35 | ribosomal protein L35 | 0.0158183 |
| PTBP3 | polypyrimidine tract binding protein 3 | 0.0156342 |
| RNF24 | ring finger protein 24 | 0.0152638 |
| PALM2AKAP2 | PALM2 and AKAP2 fusion | 0.01518 |
| RPS6 | ribosomal protein S6 | 0.0149377 |
| ALCAM | activated leukocyte cell adhesion molecule | 0.01483 |
| RPS2 | ribosomal protein S2 | 0.0146304 |
| G0S2 | G0/G1 switch 2 | 0.0145842 |
| PDGFA | platelet-derived growth factor alpha polypeptide | 0.0143035 |
| MT1X | metallothionein 1X | 0.0142802 |
| EZR | ezrin | 0.0142714 |
| LOC102724023 | ES1 protein homolog, mitochondrial | 0.0140763 |
| FHL2 | four and a half LIM domains 2 | 0.0140195 |
| SOX9 | SRY (sex determining region Y)-box 9 | 0.0136762 |
| KIF5B | kinesin family member 5B | 0.013608 |
| PPP1R12A | protein phosphatase 1, regulatory subunit 12A | 0.0135812 |
| RPL18 | ribosomal protein L18 | 0.0135802 |
| TOP1 | topoisomerase (DNA) I | 0.0134544 |
| DUSP6 | dual specificity phosphatase 6 | 0.0132161 |
| ATP2B1 | ATPase, Ca++ transporting, plasma membrane 1 | 0.0131559 |
| ZFAND6 | zinc finger, AN1-type domain 6 | 0.0128771 |
| IFI44L | interferon-induced protein 44-like | 0.0127851 |
| ISG15 | ISG15 ubiquitin-like modifier | 0.0125367 |
| EIF5B | eukaryotic translation initiation factor 5B | 0.0123104 |
| BIRC3 | baculoviral IAP repeat containing 3 | 0.0122504 |
| CTNNB1 | catenin (cadherin-associated protein), beta 1, 88kDa | 0.0122108 |
| TMC7 | transmembrane channel-like 7 | 0.0122048 |
| RBMS1 | RNA binding motif, single stranded interacting protein 1 | 0.0121247 |
| RNF149 | ring finger protein 149 | 0.0121237 |
| UQCRB | ubiquinol-cytochrome c reductase binding protein | 0.0120853 |
| TNNC1 | troponin C type 1 (slow) | 0.012064 |
| IL1R1 | interleukin 1 receptor, type I | 0.0120302 |
| OASL | 2'-5'-oligoadenylate synthetase-like | 0.0120193 |
| UBE2E3 | ubiquitin-conjugating enzyme E2E 3 | 0.0118029 |
| IFITM1 | interferon induced transmembrane protein 1 | 0.0116847 |
| ARHGAP21 | Rho GTPase activating protein 21 | 0.0116534 |
| KCNK1 | potassium channel, two pore domain subfamily K, member 1 | 0.0116165 |
| GPCPD1 | glycerophosphocholine phosphodiesterase GDE1 homolog (S. cerevisiae) | 0.0115826 |
| RB1CC1 | RB1-inducible coiled-coil 1 | 0.0115386 |
| SET | SET nuclear proto-oncogene | 0.0114428 |
| Symbol | Name | Standardized Value |
|---|---|---|
| FN1 | fibronectin 1 | -0.229536 |
| PDE4D | phosphodiesterase 4D, cAMP-specific | -0.157598 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.139988 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.130936 |
| SDK1 | sidekick cell adhesion molecule 1 | -0.123743 |
| CDH13 | cadherin 13 | -0.116619 |
| AGAP1 | ArfGAP with GTPase domain, ankyrin repeat and PH domain 1 | -0.106526 |
| ITPR1 | inositol 1,4,5-trisphosphate receptor, type 1 | -0.104429 |
| FNDC3B | fibronectin type III domain containing 3B | -0.0928724 |
| TRIO | trio Rho guanine nucleotide exchange factor | -0.0927662 |
| CAMK1D | calcium/calmodulin-dependent protein kinase ID | -0.0909636 |
| CXCL8 | chemokine (C-X-C motif) ligand 8 | -0.0862656 |
| GPC6 | glypican 6 | -0.0762898 |
| PRELID2 | PRELI domain containing 2 | -0.0732752 |
| PSD3 | pleckstrin and Sec7 domain containing 3 | -0.0725302 |
| TAS2R14 | taste receptor, type 2, member 14 | -0.0715416 |
| USP34 | ubiquitin specific peptidase 34 | -0.0703409 |
| CANX | calnexin | -0.0697835 |
| SOD2 | superoxide dismutase 2, mitochondrial | -0.069753 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.067144 |
| DST | dystonin | -0.066647 |
| DPYD | dihydropyrimidine dehydrogenase | -0.0658325 |
| FAM20C | family with sequence similarity 20, member C | -0.0656546 |
| RAB1A | RAB1A, member RAS oncogene family | -0.0631584 |
| AHNAK | AHNAK nucleoprotein | -0.0631065 |
| LOX | lysyl oxidase | -0.0612047 |
| HMGA2 | high mobility group AT-hook 2 | -0.0611863 |
| MEF2A | myocyte enhancer factor 2A | -0.0598487 |
| NHS | Nance-Horan syndrome (congenital cataracts and dental anomalies) | -0.0586246 |
| SLC5A3 | solute carrier family 5 (sodium/myo-inositol cotransporter), member 3 | -0.0572126 |
| NRG1 | neuregulin 1 | -0.055309 |
| UBR5 | ubiquitin protein ligase E3 component n-recognin 5 | -0.0538521 |
| RAI14 | retinoic acid induced 14 | -0.0529895 |
| SCD | stearoyl-CoA desaturase (delta-9-desaturase) | -0.0523966 |
| KDM2A | lysine (K)-specific demethylase 2A | -0.050542 |
| RBMS3 | RNA binding motif, single stranded interacting protein 3 | -0.0504083 |
| MAML3 | mastermind-like 3 (Drosophila) | -0.0501026 |
| OXR1 | oxidation resistance 1 | -0.0489439 |
| SEC31A | SEC31 homolog A (S. cerevisiae) | -0.0477566 |
| MTSS1 | metastasis suppressor 1 | -0.0470837 |
| PTGS2 | prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase) | -0.0469738 |
| CD55 | CD55 molecule, decay accelerating factor for complement (Cromer blood group) | -0.0469523 |
| DLG1 | discs, large homolog 1 (Drosophila) | -0.0468651 |
| FBN1 | fibrillin 1 | -0.0463915 |
| HDLBP | high density lipoprotein binding protein | -0.0461499 |
| MECOM | MDS1 and EVI1 complex locus | -0.0457359 |
| P4HB | prolyl 4-hydroxylase, beta polypeptide | -0.0446875 |
| MAGI2 | membrane associated guanylate kinase, WW and PDZ domain containing 2 | -0.0443452 |
| KCNMA1 | potassium channel, calcium activated large conductance subfamily M alpha, member 1 | -0.0419921 |
| PDIA3 | protein disulfide isomerase family A, member 3 | -0.0413837 |
| SYT1 | synaptotagmin I | -0.0413298 |
| RAD51B | RAD51 paralog B | -0.0409002 |
| LRMDA | leucine rich melanocyte differentiation associated | -0.0408557 |
| EFNA5 | ephrin-A5 | -0.0403554 |
| GALNT18 | polypeptide N-acetylgalactosaminyltransferase 18 | -0.0395212 |
| ASPH | aspartate beta-hydroxylase | -0.0389067 |
| GFPT1 | glutamine--fructose-6-phosphate transaminase 1 | -0.0386361 |
| CUX1 | cut-like homeobox 1 | -0.0380578 |
| CACNA2D3 | calcium channel, voltage-dependent, alpha 2/delta subunit 3 | -0.0375968 |
| ATXN1 | ataxin 1 | -0.0374411 |
| TTC3 | tetratricopeptide repeat domain 3 | -0.0368789 |
| MAML2 | mastermind-like 2 (Drosophila) | -0.03671 |
| PGK1 | phosphoglycerate kinase 1 | -0.0364361 |
| LPP | LIM domain containing preferred translocation partner in lipoma | -0.036414 |
| PAPPA | pregnancy-associated plasma protein A, pappalysin 1 | -0.0361765 |
| PRKCA | protein kinase C, alpha | -0.0360676 |
| LMAN1 | lectin, mannose-binding, 1 | -0.0360375 |
| ASCC3 | activating signal cointegrator 1 complex subunit 3 | -0.035803 |
| EGFR | epidermal growth factor receptor | -0.0356917 |
| KANSL1 | KAT8 regulatory NSL complex subunit 1 | -0.0353651 |
| NCOA7 | nuclear receptor coactivator 7 | -0.0349447 |
| TMTC1 | transmembrane and tetratricopeptide repeat containing 1 | -0.0345573 |
| GOLGA4 | golgin A4 | -0.0342273 |
| INPP4B | inositol polyphosphate-4-phosphatase, type II, 105kDa | -0.0340435 |
| VCL | vinculin | -0.0339298 |
| DYNC1H1 | dynein, cytoplasmic 1, heavy chain 1 | -0.0338441 |
| ASH1L | ash1 (absent, small, or homeotic)-like (Drosophila) | -0.0336692 |
| HERC4 | HECT and RLD domain containing E3 ubiquitin protein ligase 4 | -0.0336006 |
| IGFBP3 | insulin-like growth factor binding protein 3 | -0.0333902 |
| SUPT3H | suppressor of Ty 3 homolog (S. cerevisiae) | -0.0326077 |
| KCTD16 | potassium channel tetramerization domain containing 16 | -0.0324889 |
| TMEM165 | transmembrane protein 165 | -0.0317013 |
| ZNF804A | zinc finger protein 804A | -0.0315079 |
| IMMP2L | IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) | -0.0310533 |
| CDH2 | cadherin 2, type 1, N-cadherin (neuronal) | -0.0308063 |
| SUMF1 | sulfatase modifying factor 1 | -0.0305676 |
| KYNU | kynureninase | -0.0301395 |
| GREB1L | growth regulation by estrogen in breast cancer-like | -0.0300313 |
| LIMCH1 | LIM and calponin homology domains 1 | -0.0300277 |
| GRB10 | growth factor receptor-bound protein 10 | -0.0299661 |
| SEL1L | sel-1 suppressor of lin-12-like (C. elegans) | -0.0298333 |
| ZBTB1 | zinc finger and BTB domain containing 1 | -0.0297222 |
| EXT1 | exostosin glycosyltransferase 1 | -0.0293154 |
| SETD5 | SET domain containing 5 | -0.0288773 |
| CA12 | carbonic anhydrase XII | -0.0288129 |
| MAP4 | microtubule-associated protein 4 | -0.0287941 |
| HDAC4 | histone deacetylase 4 | -0.0283977 |
| PRH1 | proline-rich protein HaeIII subfamily 1 | -0.0280788 |
| HM13 | histocompatibility (minor) 13 | -0.0280279 |
| PLOD2 | procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2 | -0.0274053 |
