| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | SBI-0640756 perturbation in NCI-H2030 cell line (Tahoe Therapeutics) |
| Similar Terms | |
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200 genes differentially expressed following the SBI-0640756_NCI-H2030 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| AKAP12 | A kinase (PRKA) anchor protein 12 | 0.178775 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.118656 |
| RPS27A | ribosomal protein S27a | 0.0591323 |
| RPL4 | ribosomal protein L4 | 0.05842 |
| TPM3 | tropomyosin 3 | 0.0562291 |
| PM20D1 | peptidase M20 domain containing 1 | 0.0545536 |
| VIM | vimentin | 0.0501441 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | 0.0493219 |
| SAMD4A | sterile alpha motif domain containing 4A | 0.0476 |
| STC1 | stanniocalcin 1 | 0.0456857 |
| SMOC1 | SPARC related modular calcium binding 1 | 0.0420271 |
| BRD2 | bromodomain containing 2 | 0.0418635 |
| RPS3 | ribosomal protein S3 | 0.0406088 |
| TFPI | tissue factor pathway inhibitor (lipoprotein-associated coagulation inhibitor) | 0.0389232 |
| HLA-B | major histocompatibility complex, class I, B | 0.03788 |
| FAM107B | family with sequence similarity 107, member B | 0.0367054 |
| TM4SF1 | transmembrane 4 L six family member 1 | 0.0365122 |
| TLN1 | talin 1 | 0.0363711 |
| SPTBN1 | spectrin, beta, non-erythrocytic 1 | 0.0363075 |
| CALM1 | calmodulin 1 (phosphorylase kinase, delta) | 0.0359446 |
| ENO1 | enolase 1, (alpha) | 0.0358315 |
| HLA-A | major histocompatibility complex, class I, A | 0.0351436 |
| RPL37A | ribosomal protein L37a | 0.0346332 |
| EEF2 | eukaryotic translation elongation factor 2 | 0.0339972 |
| RPS12 | ribosomal protein S12 | 0.0336921 |
| PRRC2C | proline-rich coiled-coil 2C | 0.0335869 |
| KTN1 | kinectin 1 (kinesin receptor) | 0.0316942 |
| RABGEF1 | RAB guanine nucleotide exchange factor (GEF) 1 | 0.031621 |
| RPS17 | ribosomal protein S17 | 0.0309997 |
| PKM | pyruvate kinase, muscle | 0.0307043 |
| NR4A2 | nuclear receptor subfamily 4, group A, member 2 | 0.0306745 |
| GOLGA4 | golgin A4 | 0.0306447 |
| DHRS7 | dehydrogenase/reductase (SDR family) member 7 | 0.0294401 |
| SRRM2 | serine/arginine repetitive matrix 2 | 0.0289838 |
| ERRFI1 | ERBB receptor feedback inhibitor 1 | 0.0288533 |
| ACTR2 | ARP2 actin-related protein 2 homolog (yeast) | 0.0287669 |
| DOCK5 | dedicator of cytokinesis 5 | 0.0287108 |
| IGFBP3 | insulin-like growth factor binding protein 3 | 0.0286402 |
| UBC | ubiquitin C | 0.0286368 |
| APLP2 | amyloid beta (A4) precursor-like protein 2 | 0.028589 |
| EIF5B | eukaryotic translation initiation factor 5B | 0.0283657 |
| DYNC1H1 | dynein, cytoplasmic 1, heavy chain 1 | 0.0283331 |
| ZSWIM6 | zinc finger, SWIM-type containing 6 | 0.0282322 |
| PPP1R15A | protein phosphatase 1, regulatory subunit 15A | 0.0280951 |
| MYH9 | myosin, heavy chain 9, non-muscle | 0.0280573 |
| EIF2S2 | eukaryotic translation initiation factor 2, subunit 2 beta, 38kDa | 0.027272 |
| EPAS1 | endothelial PAS domain protein 1 | 0.0269641 |
| HGS | hepatocyte growth factor-regulated tyrosine kinase substrate | 0.026433 |
| GDI2 | GDP dissociation inhibitor 2 | 0.026366 |
| HNRNPH1 | heterogeneous nuclear ribonucleoprotein H1 (H) | 0.0262493 |
| ATXN1 | ataxin 1 | 0.0256994 |
| GOLGB1 | golgin B1 | 0.0256274 |
| ATF4 | activating transcription factor 4 | 0.0248005 |
| LOC102724023 | ES1 protein homolog, mitochondrial | 0.0242585 |
| GPATCH2L | G patch domain containing 2-like | 0.024002 |
| PFKFB3 | 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 3 | 0.0236052 |
| EGR1 | early growth response 1 | 0.0233591 |
| BIRC6 | baculoviral IAP repeat containing 6 | 0.0231348 |
| INTS6 | integrator complex subunit 6 | 0.0228015 |
| ANGPTL4 | angiopoietin-like 4 | 0.0227482 |
| RPS8 | ribosomal protein S8 | 0.0227377 |
| STAT3 | signal transducer and activator of transcription 3 (acute-phase response factor) | 0.0226321 |
| NDRG1 | N-myc downstream regulated 1 | 0.0225838 |
| DSE | dermatan sulfate epimerase | 0.0222655 |
| ELL2 | elongation factor, RNA polymerase II, 2 | 0.0221157 |
| EIF3A | eukaryotic translation initiation factor 3, subunit A | 0.0216681 |
| NEDD4 | neural precursor cell expressed, developmentally down-regulated 4, E3 ubiquitin protein ligase | 0.0214791 |
| NFE2L1 | nuclear factor, erythroid 2-like 1 | 0.0213787 |
| MYO1E | myosin IE | 0.0212422 |
| ACTN1 | actinin, alpha 1 | 0.0210737 |
| DNAJC5 | DnaJ (Hsp40) homolog, subfamily C, member 5 | 0.0209151 |
| KIF5B | kinesin family member 5B | 0.0208816 |
| CTNND1 | catenin (cadherin-associated protein), delta 1 | 0.020812 |
| RPL31 | ribosomal protein L31 | 0.0204126 |
| BMP6 | bone morphogenetic protein 6 | 0.0200866 |
| P4HB | prolyl 4-hydroxylase, beta polypeptide | 0.0200487 |
| ABTB2 | ankyrin repeat and BTB (POZ) domain containing 2 | 0.0199399 |
| HLA-E | major histocompatibility complex, class I, E | 0.0198155 |
| MCFD2 | multiple coagulation factor deficiency 2 | 0.0198037 |
| S100A11 | S100 calcium binding protein A11 | 0.0194511 |
| GIGYF2 | GRB10 interacting GYF protein 2 | 0.0193267 |
| GFPT1 | glutamine--fructose-6-phosphate transaminase 1 | 0.0192435 |
| TPI1 | triosephosphate isomerase 1 | 0.0191879 |
| STC2 | stanniocalcin 2 | 0.0189553 |
| SRP54 | signal recognition particle 54kDa | 0.0186608 |
| LAMA5 | laminin, alpha 5 | 0.0185428 |
| ABCF1 | ATP-binding cassette, sub-family F (GCN20), member 1 | 0.0182441 |
| RPS18 | ribosomal protein S18 | 0.0179687 |
| DGKD | diacylglycerol kinase, delta 130kDa | 0.0178528 |
| TMF1 | TATA element modulatory factor 1 | 0.017788 |
| TTC3 | tetratricopeptide repeat domain 3 | 0.0177659 |
| RCOR1 | REST corepressor 1 | 0.0177014 |
| PLAUR | plasminogen activator, urokinase receptor | 0.0176875 |
| SUPT6H | suppressor of Ty 6 homolog (S. cerevisiae) | 0.0174931 |
| TJP1 | tight junction protein 1 | 0.0169189 |
| CAP1 | CAP, adenylate cyclase-associated protein 1 (yeast) | 0.0166406 |
| ANKRD11 | ankyrin repeat domain 11 | 0.0165649 |
| DSPP | dentin sialophosphoprotein | 0.0164229 |
| CHD4 | chromodomain helicase DNA binding protein 4 | 0.0163115 |
| NFE2L2 | nuclear factor, erythroid 2-like 2 | 0.016116 |
| Symbol | Name | Standardized Value |
|---|---|---|
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.387215 |
| ROBO2 | roundabout, axon guidance receptor, homolog 2 (Drosophila) | -0.177686 |
| FTL | ferritin, light polypeptide | -0.157921 |
| TFPI2 | tissue factor pathway inhibitor 2 | -0.12163 |
| TMSB10 | thymosin beta 10 | -0.120916 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.115572 |
| TXNRD1 | thioredoxin reductase 1 | -0.0991109 |
| ACTG1 | actin gamma 1 | -0.079209 |
| PTK2 | protein tyrosine kinase 2 | -0.0720648 |
| RPS21 | ribosomal protein S21 | -0.06328 |
| RPS4Y1 | ribosomal protein S4, Y-linked 1 | -0.057171 |
| MKLN1 | muskelin 1, intracellular mediator containing kelch motifs | -0.0566139 |
| TPD52 | tumor protein D52 | -0.0541022 |
| USP3 | ubiquitin specific peptidase 3 | -0.0540886 |
| RAD21 | RAD21 homolog (S. pombe) | -0.0481515 |
| FTH1 | ferritin, heavy polypeptide 1 | -0.0463976 |
| ZFAND3 | zinc finger, AN1-type domain 3 | -0.0457695 |
| THSD4 | thrombospondin, type I, domain containing 4 | -0.0456001 |
| POTEF | POTE ankyrin domain family, member F | -0.0454944 |
| FGB | fibrinogen beta chain | -0.0454564 |
| YWHAZ | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta | -0.0449819 |
| CYRIB | CYFIP related Rac1 interactor B | -0.0448009 |
| RHOA | ras homolog family member A | -0.0441914 |
| RPL8 | ribosomal protein L8 | -0.0430751 |
| S100A10 | S100 calcium binding protein A10 | -0.042654 |
| PPP2R2A | protein phosphatase 2, regulatory subunit B, alpha | -0.0423572 |
| PDE4D | phosphodiesterase 4D, cAMP-specific | -0.0416043 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | -0.0415613 |
| CAVIN1 | caveolae associated protein 1 | -0.0407061 |
| RPL19 | ribosomal protein L19 | -0.040553 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.0404823 |
| IGF2 | insulin-like growth factor 2 | -0.0397394 |
| GRAMD1B | GRAM domain containing 1B | -0.0390071 |
| SLC38A1 | solute carrier family 38, member 1 | -0.0386913 |
| RTN4 | reticulon 4 | -0.0384209 |
| WDR43 | WD repeat domain 43 | -0.0381731 |
| S100A6 | S100 calcium binding protein A6 | -0.0376957 |
| CSGALNACT1 | chondroitin sulfate N-acetylgalactosaminyltransferase 1 | -0.037536 |
| SLC2A3 | solute carrier family 2 (facilitated glucose transporter), member 3 | -0.036019 |
| RPLP0 | ribosomal protein, large, P0 | -0.0360091 |
| DENND4A | DENN/MADD domain containing 4A | -0.0359434 |
| NQO1 | NAD(P)H dehydrogenase, quinone 1 | -0.0352153 |
| CXCL8 | chemokine (C-X-C motif) ligand 8 | -0.0346075 |
| RPL7 | ribosomal protein L7 | -0.0345743 |
| TMEM123 | transmembrane protein 123 | -0.0340426 |
| CYP1B1 | cytochrome P450, family 1, subfamily B, polypeptide 1 | -0.0337846 |
| ERBIN | erbb2 interacting protein | -0.033481 |
| GPRC5A | G protein-coupled receptor, class C, group 5, member A | -0.0333312 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | -0.0332296 |
| PARD3 | par-3 family cell polarity regulator | -0.0331414 |
| RPLP1 | ribosomal protein, large, P1 | -0.0330498 |
| NEGR1 | neuronal growth regulator 1 | -0.0329264 |
| RHEB | Ras homolog enriched in brain | -0.032307 |
| UTRN | utrophin | -0.0322428 |
| BHLHE40 | basic helix-loop-helix family, member e40 | -0.0322324 |
| ECT2 | epithelial cell transforming 2 | -0.0318607 |
| KLF6 | Kruppel-like factor 6 | -0.0317413 |
| LGALS1 | lectin, galactoside-binding, soluble, 1 | -0.0315182 |
| FAM168A | family with sequence similarity 168, member A | -0.0314727 |
| RPS25 | ribosomal protein S25 | -0.0311453 |
| ZNF292 | zinc finger protein 292 | -0.0310192 |
| OSBPL9 | oxysterol binding protein-like 9 | -0.0308549 |
| YBX3 | Y box binding protein 3 | -0.030114 |
| NAMPT | nicotinamide phosphoribosyltransferase | -0.0300307 |
| MRTFA | myocardin related transcription factor A | -0.0298792 |
| S100A9 | S100 calcium binding protein A9 | -0.0295163 |
| TFG | TRK-fused gene | -0.0294757 |
| CITED2 | Cbp/p300-interacting transactivator, with Glu/Asp-rich carboxy-terminal domain, 2 | -0.0294422 |
| RPS15 | ribosomal protein S15 | -0.0292091 |
| TBL1XR1 | transducin (beta)-like 1 X-linked receptor 1 | -0.0290533 |
| HDAC9 | histone deacetylase 9 | -0.0290279 |
| CHN1 | chimerin 1 | -0.0288239 |
| PFN1 | profilin 1 | -0.0287252 |
| HNRNPU | heterogeneous nuclear ribonucleoprotein U (scaffold attachment factor A) | -0.0286123 |
| BMPR1B | bone morphogenetic protein receptor, type IB | -0.0285693 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | -0.0284617 |
| RNF145 | ring finger protein 145 | -0.0283995 |
| NEDD4L | neural precursor cell expressed, developmentally down-regulated 4-like, E3 ubiquitin protein ligase | -0.0281018 |
| FNDC3B | fibronectin type III domain containing 3B | -0.0280831 |
| EIF3E | eukaryotic translation initiation factor 3, subunit E | -0.0277956 |
| RAB1A | RAB1A, member RAS oncogene family | -0.0276555 |
| KMT2E | lysine (K)-specific methyltransferase 2E | -0.0276327 |
| SERF2 | small EDRK-rich factor 2 | -0.027632 |
| CTNNB1 | catenin (cadherin-associated protein), beta 1, 88kDa | -0.0276199 |
| ANXA2 | annexin A2 | -0.0273603 |
| FNBP1L | formin binding protein 1-like | -0.027344 |
| MORF4L1 | mortality factor 4 like 1 | -0.0269268 |
| YBX1 | Y box binding protein 1 | -0.0267734 |
| AK1 | adenylate kinase 1 | -0.0265084 |
| MBNL1 | muscleblind-like splicing regulator 1 | -0.0263597 |
| BABAM2 | BRISC and BRCA1 A complex member 2 | -0.0263473 |
| PSMC6 | proteasome (prosome, macropain) 26S subunit, ATPase, 6 | -0.026222 |
| TUBB | tubulin, beta class I | -0.0261595 |
| MAP4K5 | mitogen-activated protein kinase kinase kinase kinase 5 | -0.0257671 |
| RPL32 | ribosomal protein L32 | -0.0256597 |
| MYL12B | myosin, light chain 12B, regulatory | -0.025618 |
| PLOD2 | procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2 | -0.0255531 |
| BIRC2 | baculoviral IAP repeat containing 2 | -0.0251651 |
| GNAS | GNAS complex locus | -0.0251603 |
| EFNA5 | ephrin-A5 | -0.0251551 |
