| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | SBI-0640756 perturbation in NCI-H2122 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the SBI-0640756_NCI-H2122 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| PDE4D | phosphodiesterase 4D, cAMP-specific | 0.0928706 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | 0.060434 |
| ATP1B1 | ATPase, Na+/K+ transporting, beta 1 polypeptide | 0.0543158 |
| SEMA3C | sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3C | 0.0533629 |
| KRT17 | keratin 17, type I | 0.0519126 |
| PITPNC1 | phosphatidylinositol transfer protein, cytoplasmic 1 | 0.0473222 |
| KYNU | kynureninase | 0.0455294 |
| SBF2 | SET binding factor 2 | 0.0429587 |
| ELL2 | elongation factor, RNA polymerase II, 2 | 0.042915 |
| ITGA2 | integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor) | 0.0428138 |
| CATSPERB | catsper channel auxiliary subunit beta | 0.0376742 |
| PDE10A | phosphodiesterase 10A | 0.0370097 |
| CA12 | carbonic anhydrase XII | 0.0368052 |
| PDE3A | phosphodiesterase 3A, cGMP-inhibited | 0.0365775 |
| MYO1E | myosin IE | 0.036543 |
| GPBP1 | GC-rich promoter binding protein 1 | 0.0342773 |
| BCAR3 | breast cancer anti-estrogen resistance 3 | 0.0338337 |
| EGR1 | early growth response 1 | 0.0334618 |
| PATJ | PATJ crumbs cell polarity complex component | 0.0332481 |
| ATRX | alpha thalassemia/mental retardation syndrome X-linked | 0.0321202 |
| FMNL2 | formin-like 2 | 0.0320438 |
| FHIT | fragile histidine triad | 0.0315978 |
| SNX9 | sorting nexin 9 | 0.0312939 |
| PNISR | PNN-interacting serine/arginine-rich protein | 0.0310447 |
| RPL12 | ribosomal protein L12 | 0.0310447 |
| ATF6 | activating transcription factor 6 | 0.0308672 |
| DSPP | dentin sialophosphoprotein | 0.0302828 |
| TJP1 | tight junction protein 1 | 0.0302185 |
| SREK1 | splicing regulatory glutamine/lysine-rich protein 1 | 0.0301996 |
| SLC6A14 | solute carrier family 6 (amino acid transporter), member 14 | 0.0301677 |
| DDX60 | DEAD (Asp-Glu-Ala-Asp) box polypeptide 60 | 0.0301653 |
| KIF5B | kinesin family member 5B | 0.0301431 |
| CLIP1 | CAP-GLY domain containing linker protein 1 | 0.029814 |
| PHLDB2 | pleckstrin homology-like domain, family B, member 2 | 0.0298048 |
| CD55 | CD55 molecule, decay accelerating factor for complement (Cromer blood group) | 0.029551 |
| GON4L | gon-4-like (C. elegans) | 0.0292679 |
| PPP2R2C | protein phosphatase 2, regulatory subunit B, gamma | 0.0289376 |
| GTF2IRD1 | GTF2I repeat domain containing 1 | 0.0287407 |
| ABI1 | abl-interactor 1 | 0.0285488 |
| CCDC6 | coiled-coil domain containing 6 | 0.0285481 |
| CAPZB | capping protein (actin filament) muscle Z-line, beta | 0.028214 |
| PAFAH1B1 | platelet-activating factor acetylhydrolase 1b, regulatory subunit 1 (45kDa) | 0.0281936 |
| PALM2AKAP2 | PALM2 and AKAP2 fusion | 0.0277217 |
| RPS27A | ribosomal protein S27a | 0.0275502 |
| HOOK3 | hook microtubule-tethering protein 3 | 0.0271512 |
| LRBA | LPS-responsive vesicle trafficking, beach and anchor containing | 0.0270586 |
| FEZ2 | fasciculation and elongation protein zeta 2 (zygin II) | 0.0266444 |
| IFI6 | interferon, alpha-inducible protein 6 | 0.0264686 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.0263141 |
| ZFYVE16 | zinc finger, FYVE domain containing 16 | 0.0263103 |
| LDHA | lactate dehydrogenase A | 0.0262713 |
| RPS27L | ribosomal protein S27-like | 0.0261172 |
| CXCL8 | chemokine (C-X-C motif) ligand 8 | 0.0259422 |
| SOS1 | son of sevenless homolog 1 (Drosophila) | 0.0259168 |
| CPEB4 | cytoplasmic polyadenylation element binding protein 4 | 0.0259126 |
| CSNK2A2 | casein kinase 2, alpha prime polypeptide | 0.025753 |
| MAGI2 | membrane associated guanylate kinase, WW and PDZ domain containing 2 | 0.025644 |
| TRAPPC9 | trafficking protein particle complex 9 | 0.02541 |
| XPO1 | exportin 1 | 0.0254075 |
| RSRC2 | arginine/serine-rich coiled-coil 2 | 0.025407 |
| TAX1BP1 | Tax1 (human T-cell leukemia virus type I) binding protein 1 | 0.0253264 |
| HMGA2 | high mobility group AT-hook 2 | 0.0252258 |
| VMP1 | vacuole membrane protein 1 | 0.0244923 |
| PARD3 | par-3 family cell polarity regulator | 0.0244296 |
| BLTP1 | bridge-like lipid transfer protein family member 1 | 0.0243735 |
| BRIP1 | BRCA1 interacting protein C-terminal helicase 1 | 0.0243412 |
| UBXN4 | UBX domain protein 4 | 0.0241605 |
| RPS6 | ribosomal protein S6 | 0.0239727 |
| STC1 | stanniocalcin 1 | 0.0238399 |
| RPL4 | ribosomal protein L4 | 0.0236706 |
| USP8 | ubiquitin specific peptidase 8 | 0.0236405 |
| CEACAM6 | carcinoembryonic antigen-related cell adhesion molecule 6 (non-specific cross reacting antigen) | 0.0236315 |
| SLC5A3 | solute carrier family 5 (sodium/myo-inositol cotransporter), member 3 | 0.023303 |
| MTAP | methylthioadenosine phosphorylase | 0.0228081 |
| PRPF4B | pre-mRNA processing factor 4B | 0.0226197 |
| ZKSCAN1 | zinc finger with KRAB and SCAN domains 1 | 0.0225993 |
| ACTN4 | actinin, alpha 4 | 0.022553 |
| ATOSA | atos homolog A | 0.0223731 |
| NLGN1 | neuroligin 1 | 0.0222899 |
| MAP3K20 | mitogen-activated protein kinase kinase kinase 20 | 0.0222267 |
| ARPC5 | actin related protein 2/3 complex, subunit 5, 16kDa | 0.02193 |
| SPG11 | spastic paraplegia 11 (autosomal recessive) | 0.021921 |
| RPL28 | ribosomal protein L28 | 0.0219143 |
| GPHN | gephyrin | 0.0219011 |
| BNIP3L | BCL2/adenovirus E1B 19kDa interacting protein 3-like | 0.02182 |
| RSL24D1 | ribosomal L24 domain containing 1 | 0.0217632 |
| PTPRG | protein tyrosine phosphatase, receptor type, G | 0.0217585 |
| SET | SET nuclear proto-oncogene | 0.0217415 |
| RPTOR | regulatory associated protein of MTOR, complex 1 | 0.0215959 |
| SUPT6H | suppressor of Ty 6 homolog (S. cerevisiae) | 0.0215616 |
| AUTS2 | autism susceptibility candidate 2 | 0.0213769 |
| ATP2C2 | ATPase, Ca++ transporting, type 2C, member 2 | 0.021355 |
| TLN1 | talin 1 | 0.021218 |
| VPS13B | vacuolar protein sorting 13 homolog B (yeast) | 0.0212114 |
| VCL | vinculin | 0.0211477 |
| PCNX4 | pecanex 4 | 0.0210428 |
| DDIT4 | DNA-damage-inducible transcript 4 | 0.0210344 |
| FBXO32 | F-box protein 32 | 0.0210043 |
| OXSR1 | oxidative stress responsive 1 | 0.0209911 |
| HNRNPA1 | heterogeneous nuclear ribonucleoprotein A1 | 0.0208803 |
| Symbol | Name | Standardized Value |
|---|---|---|
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.0884754 |
| NDRG1 | N-myc downstream regulated 1 | -0.082765 |
| MT2A | metallothionein 2A | -0.0575976 |
| PRKCA | protein kinase C, alpha | -0.0550301 |
| FNDC3B | fibronectin type III domain containing 3B | -0.050854 |
| ESYT2 | extended synaptotagmin-like protein 2 | -0.0504642 |
| VIM | vimentin | -0.0495429 |
| JMJD1C | jumonji domain containing 1C | -0.0479208 |
| P4HA1 | prolyl 4-hydroxylase, alpha polypeptide I | -0.0465695 |
| ZC3HAV1 | zinc finger CCCH-type, antiviral 1 | -0.0459413 |
| MARCHF6 | membrane associated ring-CH-type finger 6 | -0.0450698 |
| SEC31A | SEC31 homolog A (S. cerevisiae) | -0.044684 |
| TMSB10 | thymosin beta 10 | -0.0446707 |
| B2M | beta-2-microglobulin | -0.0407369 |
| PTMA | prothymosin, alpha | -0.040158 |
| ZNF638 | zinc finger protein 638 | -0.0386449 |
| S100A10 | S100 calcium binding protein A10 | -0.0368513 |
| TAF15 | TAF15 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 68kDa | -0.0348868 |
| AK1 | adenylate kinase 1 | -0.034675 |
| NAMPT | nicotinamide phosphoribosyltransferase | -0.0344089 |
| KRT19 | keratin 19, type I | -0.0336717 |
| PLOD2 | procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2 | -0.0333135 |
| RTN4 | reticulon 4 | -0.0324348 |
| RBPJ | recombination signal binding protein for immunoglobulin kappa J region | -0.0321555 |
| GRB10 | growth factor receptor-bound protein 10 | -0.0320248 |
| SMYD3 | SET and MYND domain containing 3 | -0.0317522 |
| CALU | calumenin | -0.0316758 |
| SND1 | staphylococcal nuclease and tudor domain containing 1 | -0.0316301 |
| RPS21 | ribosomal protein S21 | -0.0315489 |
| TENT5A | terminal nucleotidyltransferase 5A | -0.0312532 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | -0.0310767 |
| RIGI | RNA sensor RIG-I | -0.030498 |
| RPS19 | ribosomal protein S19 | -0.0301712 |
| LIMA1 | LIM domain and actin binding 1 | -0.0301657 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.0298804 |
| HNRNPU | heterogeneous nuclear ribonucleoprotein U (scaffold attachment factor A) | -0.0293057 |
| STAT1 | signal transducer and activator of transcription 1, 91kDa | -0.0292726 |
| RPL35A | ribosomal protein L35a | -0.0289368 |
| RAB7A | RAB7A, member RAS oncogene family | -0.0278996 |
| TM4SF1 | transmembrane 4 L six family member 1 | -0.0275078 |
| APP | amyloid beta (A4) precursor protein | -0.0273249 |
| PAN3 | PAN3 poly(A) specific ribonuclease subunit | -0.0271937 |
| ZMYND8 | zinc finger, MYND-type containing 8 | -0.0267591 |
| STAU1 | staufen double-stranded RNA binding protein 1 | -0.0266749 |
| CNNM2 | cyclin and CBS domain divalent metal cation transport mediator 2 | -0.0266556 |
| ARHGAP12 | Rho GTPase activating protein 12 | -0.0264818 |
| TMEM165 | transmembrane protein 165 | -0.0264763 |
| GPRC5A | G protein-coupled receptor, class C, group 5, member A | -0.0264629 |
| UBC | ubiquitin C | -0.0263713 |
| ADAM17 | ADAM metallopeptidase domain 17 | -0.0263367 |
| SFTPA2 | surfactant protein A2 | -0.0263155 |
| RPL11 | ribosomal protein L11 | -0.0263018 |
| SMURF2 | SMAD specific E3 ubiquitin protein ligase 2 | -0.0261694 |
| ANKRD12 | ankyrin repeat domain 12 | -0.0258894 |
| ZNFX1 | zinc finger, NFX1-type containing 1 | -0.0258095 |
| RPS3 | ribosomal protein S3 | -0.0257348 |
| ARHGAP21 | Rho GTPase activating protein 21 | -0.0256721 |
| RAB22A | RAB22A, member RAS oncogene family | -0.025408 |
| KANSL1 | KAT8 regulatory NSL complex subunit 1 | -0.0251317 |
| IBTK | inhibitor of Bruton agammaglobulinemia tyrosine kinase | -0.0250655 |
| KMT2A | lysine (K)-specific methyltransferase 2A | -0.0247297 |
| BNIP3 | BCL2/adenovirus E1B 19kDa interacting protein 3 | -0.0246647 |
| NUMB | numb homolog (Drosophila) | -0.0245756 |
| PPP2R5E | protein phosphatase 2, regulatory subunit B', epsilon isoform | -0.0245635 |
| RPLP1 | ribosomal protein, large, P1 | -0.0245612 |
| PTEN | phosphatase and tensin homolog | -0.0244348 |
| CD44 | CD44 molecule (Indian blood group) | -0.0243583 |
| PHF3 | PHD finger protein 3 | -0.0241946 |
| NAP1L1 | nucleosome assembly protein 1-like 1 | -0.0239714 |
| ENO1 | enolase 1, (alpha) | -0.0238124 |
| KMT2C | lysine (K)-specific methyltransferase 2C | -0.023739 |
| SEC23A | Sec23 homolog A (S. cerevisiae) | -0.0235091 |
| KPNA4 | karyopherin alpha 4 (importin alpha 3) | -0.0231877 |
| TBC1D22A | TBC1 domain family, member 22A | -0.0231389 |
| YTHDC1 | YTH domain containing 1 | -0.0229903 |
| RASA2 | RAS p21 protein activator 2 | -0.0226767 |
| BBX | bobby sox homolog (Drosophila) | -0.0225221 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | -0.0225131 |
| UBE2H | ubiquitin-conjugating enzyme E2H | -0.0223354 |
| MAP3K2 | mitogen-activated protein kinase kinase kinase 2 | -0.0221049 |
| RNF149 | ring finger protein 149 | -0.0221019 |
| MPZL1 | myelin protein zero-like 1 | -0.0219275 |
| METTL15 | methyltransferase like 15 | -0.021866 |
| TMSB4X | thymosin beta 4, X-linked | -0.0217378 |
| RPS11 | ribosomal protein S11 | -0.0215663 |
| MNAT1 | MNAT CDK-activating kinase assembly factor 1 | -0.0215591 |
| UBE3C | ubiquitin protein ligase E3C | -0.021405 |
| ZBTB43 | zinc finger and BTB domain containing 43 | -0.0212845 |
| OGA | O-GlcNAcase | -0.0209101 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | -0.0209006 |
| FOXJ3 | forkhead box J3 | -0.0207309 |
| DSCAM | Down syndrome cell adhesion molecule | -0.0205824 |
| SRPK2 | SRSF protein kinase 2 | -0.020421 |
| UMAD1 | UBAP1-MVB12-associated (UMA) domain containing 1 | -0.0203541 |
| ITCH | itchy E3 ubiquitin protein ligase | -0.0202373 |
| KIF13A | kinesin family member 13A | -0.0201741 |
| PKM | pyruvate kinase, muscle | -0.0201735 |
| PFKFB3 | 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 3 | -0.0201435 |
| UBE2O | ubiquitin-conjugating enzyme E2O | -0.019801 |
| RPRD2 | regulation of nuclear pre-mRNA domain containing 2 | -0.0194886 |
