| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | SBI-0640756 perturbation in NCI-H596 cell line (Tahoe Therapeutics) |
| Similar Terms | |
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119 genes differentially expressed following the SBI-0640756_NCI-H596 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| ARHGAP32 | Rho GTPase activating protein 32 | 0.116136 |
| RPS19 | ribosomal protein S19 | 0.108392 |
| SVIL | supervillin | 0.104166 |
| LOC102724023 | ES1 protein homolog, mitochondrial | 0.100237 |
| RPLP1 | ribosomal protein, large, P1 | 0.0999189 |
| RPL13A | ribosomal protein L13a | 0.0974097 |
| N4BP2L2 | NEDD4 binding protein 2-like 2 | 0.0941807 |
| ERRFI1 | ERBB receptor feedback inhibitor 1 | 0.0907717 |
| ACBD3 | acyl-CoA binding domain containing 3 | 0.089368 |
| RPS13 | ribosomal protein S13 | 0.0891879 |
| CALM2 | calmodulin 2 (phosphorylase kinase, delta) | 0.0887866 |
| ITGB1 | integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) | 0.0868433 |
| RPL31 | ribosomal protein L31 | 0.0834962 |
| MMAB | methylmalonic aciduria (cobalamin deficiency) cblB type | 0.0824354 |
| ENO1 | enolase 1, (alpha) | 0.0808218 |
| PTK2 | protein tyrosine kinase 2 | 0.0753926 |
| ACTG1 | actin gamma 1 | 0.0747652 |
| IGF2 | insulin-like growth factor 2 | 0.0735112 |
| USP34 | ubiquitin specific peptidase 34 | 0.0729298 |
| LDHA | lactate dehydrogenase A | 0.0688517 |
| RPS27A | ribosomal protein S27a | 0.0676342 |
| MACF1 | microtubule-actin crosslinking factor 1 | 0.0673509 |
| ZSWIM6 | zinc finger, SWIM-type containing 6 | 0.0638286 |
| HNRNPA1 | heterogeneous nuclear ribonucleoprotein A1 | 0.0632328 |
| HNRNPC | heterogeneous nuclear ribonucleoprotein C (C1/C2) | 0.0629492 |
| FN1 | fibronectin 1 | 0.0599164 |
| PITPNC1 | phosphatidylinositol transfer protein, cytoplasmic 1 | 0.0589079 |
| MAGI2 | membrane associated guanylate kinase, WW and PDZ domain containing 2 | 0.0581672 |
| RPS16 | ribosomal protein S16 | 0.0567696 |
| EEF2 | eukaryotic translation elongation factor 2 | 0.052039 |
| EXT1 | exostosin glycosyltransferase 1 | 0.0515406 |
| MYO1E | myosin IE | 0.0471288 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | 0.0465686 |
| RPS12 | ribosomal protein S12 | 0.0460856 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.0459152 |
| SQSTM1 | sequestosome 1 | 0.0434889 |
| VCL | vinculin | 0.0404399 |
| AKAP12 | A kinase (PRKA) anchor protein 12 | 0.0358533 |
| VIM | vimentin | 0.0358348 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | 0.0334674 |
| GMDS | GDP-mannose 4,6-dehydratase | 0.0319197 |
| EIF1 | eukaryotic translation initiation factor 1 | 0.0300071 |
| DSCAM | Down syndrome cell adhesion molecule | 0.0286863 |
| RPS8 | ribosomal protein S8 | 0.0253076 |
| KMT2E | lysine (K)-specific methyltransferase 2E | 0.0208295 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | 0.020361 |
| POTEF | POTE ankyrin domain family, member F | 0.0200888 |
| GPC6 | glypican 6 | 0.0172611 |
| AKAP13 | A kinase (PRKA) anchor protein 13 | 0.0165441 |
| FTL | ferritin, light polypeptide | 0.0164234 |
| FTH1 | ferritin, heavy polypeptide 1 | 0.0159755 |
| RPS6 | ribosomal protein S6 | 0.0155236 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | 0.0137854 |
| RPL37A | ribosomal protein L37a | 0.0129727 |
| NAP1L1 | nucleosome assembly protein 1-like 1 | 0.00996499 |
| IMMP2L | IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) | 0.00799 |
| TAS2R14 | taste receptor, type 2, member 14 | 0.00680716 |
| TMSB10 | thymosin beta 10 | 0.00511584 |
| ESYT2 | extended synaptotagmin-like protein 2 | 0.00357819 |
| ALCAM | activated leukocyte cell adhesion molecule | 0.00214767 |
| IGFBP3 | insulin-like growth factor binding protein 3 | 0.00158394 |
| Symbol | Name | Standardized Value |
|---|---|---|
| PDE4D | phosphodiesterase 4D, cAMP-specific | -0.476882 |
| EGFR | epidermal growth factor receptor | -0.120687 |
| PDE3A | phosphodiesterase 3A, cGMP-inhibited | -0.120625 |
| ZC3HAV1 | zinc finger CCCH-type, antiviral 1 | -0.118234 |
| FNDC3B | fibronectin type III domain containing 3B | -0.112541 |
| KMT2C | lysine (K)-specific methyltransferase 2C | -0.101848 |
| SLC2A13 | solute carrier family 2 (facilitated glucose transporter), member 13 | -0.101719 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.0978146 |
| CDH13 | cadherin 13 | -0.0824061 |
| GRB10 | growth factor receptor-bound protein 10 | -0.0795117 |
| PLCB1 | phospholipase C, beta 1 (phosphoinositide-specific) | -0.0759701 |
| THSD4 | thrombospondin, type I, domain containing 4 | -0.074 |
| PDLIM5 | PDZ and LIM domain 5 | -0.0664264 |
| APP | amyloid beta (A4) precursor protein | -0.0647807 |
| PDE10A | phosphodiesterase 10A | -0.0578538 |
| PARD3 | par-3 family cell polarity regulator | -0.0567693 |
| FNDC3A | fibronectin type III domain containing 3A | -0.056739 |
| SHANK2 | SH3 and multiple ankyrin repeat domains 2 | -0.0551302 |
| HNRNPU | heterogeneous nuclear ribonucleoprotein U (scaffold attachment factor A) | -0.0518547 |
| BBX | bobby sox homolog (Drosophila) | -0.0498029 |
| RIGI | RNA sensor RIG-I | -0.0486306 |
| TCF12 | transcription factor 12 | -0.0438179 |
| TAX1BP1 | Tax1 (human T-cell leukemia virus type I) binding protein 1 | -0.0427887 |
| SAMD4A | sterile alpha motif domain containing 4A | -0.0424559 |
| ASPH | aspartate beta-hydroxylase | -0.041093 |
| SRGAP1 | SLIT-ROBO Rho GTPase activating protein 1 | -0.0395615 |
| DOCK4 | dedicator of cytokinesis 4 | -0.039453 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | -0.0392564 |
| PSD3 | pleckstrin and Sec7 domain containing 3 | -0.0382754 |
| SMAD3 | SMAD family member 3 | -0.036815 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.0363619 |
| AGAP1 | ArfGAP with GTPase domain, ankyrin repeat and PH domain 1 | -0.0356994 |
| PRRC2C | proline-rich coiled-coil 2C | -0.0334882 |
| SRPK2 | SRSF protein kinase 2 | -0.0321824 |
| MAP4K4 | mitogen-activated protein kinase kinase kinase kinase 4 | -0.0313029 |
| SETD5 | SET domain containing 5 | -0.0298276 |
| SLTM | SAFB-like, transcription modulator | -0.0287685 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.0281179 |
| HERC4 | HECT and RLD domain containing E3 ubiquitin protein ligase 4 | -0.0280023 |
| CPEB4 | cytoplasmic polyadenylation element binding protein 4 | -0.0269016 |
| RORA | RAR-related orphan receptor A | -0.0267883 |
| TXNRD1 | thioredoxin reductase 1 | -0.026084 |
| TRIO | trio Rho guanine nucleotide exchange factor | -0.0247216 |
| JMJD1C | jumonji domain containing 1C | -0.0243602 |
| TANC2 | tetratricopeptide repeat, ankyrin repeat and coiled-coil containing 2 | -0.0209925 |
| DCBLD2 | discoidin, CUB and LCCL domain containing 2 | -0.0205051 |
| CD55 | CD55 molecule, decay accelerating factor for complement (Cromer blood group) | -0.0192147 |
| PLEKHA5 | pleckstrin homology domain containing, family A member 5 | -0.0183054 |
| NUFIP2 | nuclear fragile X mental retardation protein interacting protein 2 | -0.0172046 |
| PTMA | prothymosin, alpha | -0.0120248 |
| MCL1 | myeloid cell leukemia 1 | -0.0119234 |
| TAF15 | TAF15 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 68kDa | -0.011148 |
| NBEAL1 | neurobeachin-like 1 | -0.0105618 |
| MT2A | metallothionein 2A | -0.0102013 |
| KDM2A | lysine (K)-specific demethylase 2A | -0.0052345 |
| SND1 | staphylococcal nuclease and tudor domain containing 1 | -0.0046479 |
| ITGA2 | integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor) | -0.00240686 |
| RPL35A | ribosomal protein L35a | -0.00215306 |
