| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | SBI-0640756 perturbation in NCI-H661 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the SBI-0640756_NCI-H661 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| DST | dystonin | 0.0647066 |
| STC1 | stanniocalcin 1 | 0.0552777 |
| CCDC88A | coiled-coil domain containing 88A | 0.0526412 |
| LRRFIP1 | leucine rich repeat (in FLII) interacting protein 1 | 0.0493747 |
| SPTBN1 | spectrin, beta, non-erythrocytic 1 | 0.0488462 |
| PRRC2C | proline-rich coiled-coil 2C | 0.0469457 |
| MMAB | methylmalonic aciduria (cobalamin deficiency) cblB type | 0.0404082 |
| ANKRD11 | ankyrin repeat domain 11 | 0.0390172 |
| PDE4D | phosphodiesterase 4D, cAMP-specific | 0.038795 |
| AKAP9 | A kinase (PRKA) anchor protein 9 | 0.038498 |
| RPS12 | ribosomal protein S12 | 0.0364405 |
| EGFR | epidermal growth factor receptor | 0.0362439 |
| HIVEP2 | human immunodeficiency virus type I enhancer binding protein 2 | 0.0326527 |
| SREBF2 | sterol regulatory element binding transcription factor 2 | 0.032016 |
| ANKRD12 | ankyrin repeat domain 12 | 0.0311919 |
| SMG1 | SMG1 phosphatidylinositol 3-kinase-related kinase | 0.0306459 |
| EZR | ezrin | 0.0302272 |
| PSD3 | pleckstrin and Sec7 domain containing 3 | 0.0284386 |
| MYO10 | myosin X | 0.0284163 |
| HDAC9 | histone deacetylase 9 | 0.0283407 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | 0.027553 |
| OSBPL8 | oxysterol binding protein-like 8 | 0.0274609 |
| NR3C1 | nuclear receptor subfamily 3, group C, member 1 (glucocorticoid receptor) | 0.0267773 |
| NALF1 | NALCN channel auxiliary factor 1 | 0.0266036 |
| BAZ1B | bromodomain adjacent to zinc finger domain, 1B | 0.0265203 |
| ATXN1 | ataxin 1 | 0.0260906 |
| RSF1 | remodeling and spacing factor 1 | 0.0260262 |
| PSME4 | proteasome (prosome, macropain) activator subunit 4 | 0.025784 |
| SMYD3 | SET and MYND domain containing 3 | 0.0255777 |
| HLA-A | major histocompatibility complex, class I, A | 0.0253503 |
| MYH9 | myosin, heavy chain 9, non-muscle | 0.0248596 |
| RNF24 | ring finger protein 24 | 0.0247183 |
| NCOR2 | nuclear receptor corepressor 2 | 0.0242107 |
| ZNF292 | zinc finger protein 292 | 0.0240353 |
| ITGA2 | integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor) | 0.0238085 |
| BRD2 | bromodomain containing 2 | 0.0236108 |
| KMT2C | lysine (K)-specific methyltransferase 2C | 0.0236 |
| PDE8A | phosphodiesterase 8A | 0.02344 |
| GOLGB1 | golgin B1 | 0.0233764 |
| ZNF638 | zinc finger protein 638 | 0.02337 |
| MBOAT2 | membrane bound O-acyltransferase domain containing 2 | 0.0233496 |
| JARID2 | jumonji, AT rich interactive domain 2 | 0.0229773 |
| SLC16A3 | solute carrier family 16 (monocarboxylate transporter), member 3 | 0.0229564 |
| PCMTD1 | protein-L-isoaspartate (D-aspartate) O-methyltransferase domain containing 1 | 0.0229237 |
| GIGYF2 | GRB10 interacting GYF protein 2 | 0.0227616 |
| MYO6 | myosin VI | 0.0227541 |
| KYNU | kynureninase | 0.0226818 |
| PCM1 | pericentriolar material 1 | 0.022675 |
| KDM7A | lysine (K)-specific demethylase 7A | 0.0224281 |
| AKAP12 | A kinase (PRKA) anchor protein 12 | 0.0220352 |
| RALA | v-ral simian leukemia viral oncogene homolog A (ras related) | 0.021114 |
| DOCK9 | dedicator of cytokinesis 9 | 0.0210091 |
| ENO1 | enolase 1, (alpha) | 0.0208205 |
| DGKD | diacylglycerol kinase, delta 130kDa | 0.0206918 |
| CXCL8 | chemokine (C-X-C motif) ligand 8 | 0.0206472 |
| PRRC2A | proline-rich coiled-coil 2A | 0.0206373 |
| KIF1B | kinesin family member 1B | 0.0206214 |
| SMAP1 | small ArfGAP 1 | 0.020576 |
| RPL26 | ribosomal protein L26 | 0.0204997 |
| BNIP3 | BCL2/adenovirus E1B 19kDa interacting protein 3 | 0.0202516 |
| AKAP13 | A kinase (PRKA) anchor protein 13 | 0.0201644 |
| BCCIP | BRCA2 and CDKN1A interacting protein | 0.0200164 |
| PLCB4 | phospholipase C, beta 4 | 0.0199969 |
| RSRC2 | arginine/serine-rich coiled-coil 2 | 0.0199288 |
| JMJD1C | jumonji domain containing 1C | 0.0198732 |
| AARS1 | alanyl-tRNA synthetase 1 | 0.0197179 |
| ATAD2B | ATPase family, AAA domain containing 2B | 0.0196855 |
| DSPP | dentin sialophosphoprotein | 0.0196136 |
| ATF6 | activating transcription factor 6 | 0.0196067 |
| QSOX1 | quiescin Q6 sulfhydryl oxidase 1 | 0.0195998 |
| DENND5A | DENN/MADD domain containing 5A | 0.0194302 |
| ARHGAP5 | Rho GTPase activating protein 5 | 0.0194296 |
| SH3KBP1 | SH3-domain kinase binding protein 1 | 0.0193847 |
| DIXDC1 | DIX domain containing 1 | 0.0193238 |
| DYNC1LI2 | dynein, cytoplasmic 1, light intermediate chain 2 | 0.0192455 |
| GPBP1 | GC-rich promoter binding protein 1 | 0.0192383 |
| FOXN3 | forkhead box N3 | 0.0191053 |
| CTNNA1 | catenin (cadherin-associated protein), alpha 1, 102kDa | 0.0190596 |
| PLEKHM3 | pleckstrin homology domain containing, family M, member 3 | 0.0189653 |
| SYNE2 | spectrin repeat containing, nuclear envelope 2 | 0.0188556 |
| CDK6 | cyclin-dependent kinase 6 | 0.0186503 |
| CHMP2B | charged multivesicular body protein 2B | 0.0185884 |
| NUP107 | nucleoporin 107kDa | 0.018521 |
| HLA-B | major histocompatibility complex, class I, B | 0.0184836 |
| SBF2 | SET binding factor 2 | 0.0183671 |
| BACE2 | beta-site APP-cleaving enzyme 2 | 0.018174 |
| SMAD3 | SMAD family member 3 | 0.0181299 |
| NAV1 | neuron navigator 1 | 0.0181216 |
| ANKFY1 | ankyrin repeat and FYVE domain containing 1 | 0.0181131 |
| MAGI3 | membrane associated guanylate kinase, WW and PDZ domain containing 3 | 0.018097 |
| SULF2 | sulfatase 2 | 0.0180854 |
| ABTB2 | ankyrin repeat and BTB (POZ) domain containing 2 | 0.0180424 |
| UBN1 | ubinuclein 1 | 0.0179775 |
| ATF3 | activating transcription factor 3 | 0.0179153 |
| PDE7A | phosphodiesterase 7A | 0.0178192 |
| IQSEC1 | IQ motif and Sec7 domain 1 | 0.0176545 |
| AFF1 | AF4/FMR2 family, member 1 | 0.0176507 |
| KLF10 | Kruppel-like factor 10 | 0.0175984 |
| CRTC3 | CREB regulated transcription coactivator 3 | 0.0175889 |
| RABGEF1 | RAB guanine nucleotide exchange factor (GEF) 1 | 0.0175392 |
| Symbol | Name | Standardized Value |
|---|---|---|
| COL11A1 | collagen, type XI, alpha 1 | -0.134013 |
| IMMP2L | IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) | -0.129856 |
| VIM | vimentin | -0.121418 |
| RPS16 | ribosomal protein S16 | -0.109988 |
| CADM2 | cell adhesion molecule 2 | -0.0984307 |
| PTMA | prothymosin, alpha | -0.0861299 |
| CDH6 | cadherin 6, type 2, K-cadherin (fetal kidney) | -0.082875 |
| COL3A1 | collagen, type III, alpha 1 | -0.0800701 |
| TMSB10 | thymosin beta 10 | -0.0789488 |
| ADGRL2 | adhesion G protein-coupled receptor L2 | -0.078945 |
| ERBB4 | erb-b2 receptor tyrosine kinase 4 | -0.0782313 |
| HSPD1 | heat shock 60kDa protein 1 (chaperonin) | -0.0768589 |
| COL5A2 | collagen, type V, alpha 2 | -0.0732026 |
| HNRNPU | heterogeneous nuclear ribonucleoprotein U (scaffold attachment factor A) | -0.0698371 |
| COL1A2 | collagen, type I, alpha 2 | -0.0689615 |
| PCDH9 | protocadherin 9 | -0.0672841 |
| ZFAND3 | zinc finger, AN1-type domain 3 | -0.0666448 |
| GPC3 | glypican 3 | -0.0653657 |
| PEG10 | paternally expressed 10 | -0.0650109 |
| CDH10 | cadherin 10, type 2 (T2-cadherin) | -0.0647359 |
| THBS1 | thrombospondin 1 | -0.0623269 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | -0.0620707 |
| RBMS3 | RNA binding motif, single stranded interacting protein 3 | -0.0619879 |
| TMSB4X | thymosin beta 4, X-linked | -0.0584869 |
| POTEF | POTE ankyrin domain family, member F | -0.0551062 |
| ACTG1 | actin gamma 1 | -0.0537752 |
| NUCKS1 | nuclear casein kinase and cyclin-dependent kinase substrate 1 | -0.0518359 |
| MYL12B | myosin, light chain 12B, regulatory | -0.050995 |
| GNAS | GNAS complex locus | -0.0503859 |
| RPL11 | ribosomal protein L11 | -0.0503858 |
| MDK | midkine (neurite growth-promoting factor 2) | -0.0484964 |
| SLC5A3 | solute carrier family 5 (sodium/myo-inositol cotransporter), member 3 | -0.0472995 |
| MKI67 | marker of proliferation Ki-67 | -0.0445712 |
| CALR | calreticulin | -0.0442365 |
| MEIS2 | Meis homeobox 2 | -0.044076 |
| ITGAV | integrin, alpha V | -0.0423788 |
| GALNTL6 | polypeptide N-acetylgalactosaminyltransferase-like 6 | -0.0412463 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.0411024 |
| PDIA3 | protein disulfide isomerase family A, member 3 | -0.0404716 |
| YWHAZ | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta | -0.0401765 |
| CENPF | centromere protein F, 350/400kDa | -0.0398788 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | -0.0392842 |
| HCN1 | hyperpolarization activated cyclic nucleotide gated potassium channel 1 | -0.0392109 |
| TOP2A | topoisomerase (DNA) II alpha 170kDa | -0.0386207 |
| RAPGEF2 | Rap guanine nucleotide exchange factor (GEF) 2 | -0.037473 |
| ISG15 | ISG15 ubiquitin-like modifier | -0.0371041 |
| PBX3 | pre-B-cell leukemia homeobox 3 | -0.0367822 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | -0.0365131 |
| ZC3HAV1 | zinc finger CCCH-type, antiviral 1 | -0.0363902 |
| RPLP1 | ribosomal protein, large, P1 | -0.0361334 |
| STRN3 | striatin, calmodulin binding protein 3 | -0.0359037 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.0357104 |
| SEMA3D | sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3D | -0.0356397 |
| CDH19 | cadherin 19, type 2 | -0.0351984 |
| TSC22D2 | TSC22 domain family, member 2 | -0.0351158 |
| TENM3 | teneurin transmembrane protein 3 | -0.0347665 |
| RFPL4B | ret finger protein-like 4B | -0.0345109 |
| RSL1D1 | ribosomal L1 domain containing 1 | -0.0342815 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.0339119 |
| MRPS30 | mitochondrial ribosomal protein S30 | -0.033759 |
| GULP1 | GULP, engulfment adaptor PTB domain containing 1 | -0.0337187 |
| SRPK2 | SRSF protein kinase 2 | -0.0330506 |
| TRPS1 | trichorhinophalangeal syndrome I | -0.0330008 |
| RAI1 | retinoic acid induced 1 | -0.0330006 |
| MAP1LC3B | microtubule-associated protein 1 light chain 3 beta | -0.0329139 |
| RPS21 | ribosomal protein S21 | -0.0325241 |
| PUM1 | pumilio RNA-binding family member 1 | -0.0325062 |
| IGF1R | insulin-like growth factor 1 receptor | -0.0319296 |
| SFRP4 | secreted frizzled-related protein 4 | -0.0317835 |
| RPS8 | ribosomal protein S8 | -0.031342 |
| CTNNA2 | catenin (cadherin-associated protein), alpha 2 | -0.0313371 |
| MED12L | mediator complex subunit 12-like | -0.0311558 |
| STAG2 | stromal antigen 2 | -0.0305012 |
| RPL37 | ribosomal protein L37 | -0.0304348 |
| RPS27A | ribosomal protein S27a | -0.030199 |
| FOXP2 | forkhead box P2 | -0.0301916 |
| PARD3B | par-3 family cell polarity regulator beta | -0.0301633 |
| HACD3 | 3-hydroxyacyl-CoA dehydratase 3 | -0.0300547 |
| PSMA7 | proteasome (prosome, macropain) subunit, alpha type, 7 | -0.0297265 |
| METAP2 | methionyl aminopeptidase 2 | -0.0297146 |
| HNRNPR | heterogeneous nuclear ribonucleoprotein R | -0.0295928 |
| FBL | fibrillarin | -0.0291708 |
| RPL23 | ribosomal protein L23 | -0.0291002 |
| ADAM9 | ADAM metallopeptidase domain 9 | -0.0290596 |
| RPL35A | ribosomal protein L35a | -0.0289446 |
| DEK | DEK proto-oncogene | -0.0288459 |
| ENAH | enabled homolog (Drosophila) | -0.0286524 |
| CNRIP1 | cannabinoid receptor interacting protein 1 | -0.0278976 |
| MPG | N-methylpurine-DNA glycosylase | -0.0278612 |
| HDAC2 | histone deacetylase 2 | -0.0277488 |
| RPL12 | ribosomal protein L12 | -0.0276589 |
| FAM171B | family with sequence similarity 171, member B | -0.0274075 |
| EMP1 | epithelial membrane protein 1 | -0.027378 |
| PTGES3 | prostaglandin E synthase 3 (cytosolic) | -0.0269034 |
| NEBL | nebulette | -0.0266204 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | -0.026605 |
| CTNNA3 | catenin (cadherin-associated protein), alpha 3 | -0.0265735 |
| ANK2 | ankyrin 2, neuronal | -0.0261305 |
| ATP5F1B | ATP synthase F1 subunit beta | -0.0261185 |
| CCT8 | chaperonin containing TCP1, subunit 8 (theta) | -0.0261062 |
