| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | SBI-0640756 perturbation in PANC-1 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the SBI-0640756_PANC-1 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| PTMA | prothymosin, alpha | 0.145215 |
| VCL | vinculin | 0.0930553 |
| RPS3 | ribosomal protein S3 | 0.0908867 |
| EGR1 | early growth response 1 | 0.0859262 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.0802669 |
| RPS12 | ribosomal protein S12 | 0.0768426 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | 0.0705714 |
| APLP2 | amyloid beta (A4) precursor-like protein 2 | 0.0695875 |
| KCNMA1 | potassium channel, calcium activated large conductance subfamily M alpha, member 1 | 0.0667687 |
| RPL37A | ribosomal protein L37a | 0.0648519 |
| MT2A | metallothionein 2A | 0.0598169 |
| SERPINE1 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1 | 0.0562713 |
| WSB1 | WD repeat and SOCS box containing 1 | 0.056066 |
| ZSWIM6 | zinc finger, SWIM-type containing 6 | 0.0552673 |
| EIF1 | eukaryotic translation initiation factor 1 | 0.053842 |
| INTS6 | integrator complex subunit 6 | 0.0532763 |
| RPL35A | ribosomal protein L35a | 0.0530193 |
| CALM1 | calmodulin 1 (phosphorylase kinase, delta) | 0.052817 |
| SAMD4B | sterile alpha motif domain containing 4B | 0.0524437 |
| RACK1 | receptor for activated C kinase 1 | 0.0498874 |
| FTL | ferritin, light polypeptide | 0.0496332 |
| GARS1 | glycyl-tRNA synthetase 1 | 0.0493999 |
| AP2B1 | adaptor-related protein complex 2, beta 1 subunit | 0.0488745 |
| ANKRD11 | ankyrin repeat domain 11 | 0.0483473 |
| ELL2 | elongation factor, RNA polymerase II, 2 | 0.0481994 |
| NFKBIA | nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha | 0.0478675 |
| SMG1 | SMG1 phosphatidylinositol 3-kinase-related kinase | 0.0477439 |
| DDIT4 | DNA-damage-inducible transcript 4 | 0.0476856 |
| PLEKHG2 | pleckstrin homology domain containing, family G (with RhoGef domain) member 2 | 0.0471698 |
| BRD2 | bromodomain containing 2 | 0.0465796 |
| SUPT5H | suppressor of Ty 5 homolog (S. cerevisiae) | 0.0461198 |
| SPAG9 | sperm associated antigen 9 | 0.0443794 |
| MYO1E | myosin IE | 0.0433551 |
| TLN1 | talin 1 | 0.0415255 |
| RPS17 | ribosomal protein S17 | 0.0414152 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | 0.0411942 |
| NAP1L1 | nucleosome assembly protein 1-like 1 | 0.0409607 |
| EIF2S2 | eukaryotic translation initiation factor 2, subunit 2 beta, 38kDa | 0.0408364 |
| ICAM1 | intercellular adhesion molecule 1 | 0.0403885 |
| SQSTM1 | sequestosome 1 | 0.0392371 |
| PTP4A2 | protein tyrosine phosphatase type IVA, member 2 | 0.0383006 |
| HIVEP2 | human immunodeficiency virus type I enhancer binding protein 2 | 0.0382279 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | 0.0381751 |
| ADM | adrenomedullin | 0.0381258 |
| RAB7A | RAB7A, member RAS oncogene family | 0.0379701 |
| LRRFIP1 | leucine rich repeat (in FLII) interacting protein 1 | 0.0370072 |
| SRRM2 | serine/arginine repetitive matrix 2 | 0.0361702 |
| GPBP1 | GC-rich promoter binding protein 1 | 0.0359084 |
| ERRFI1 | ERBB receptor feedback inhibitor 1 | 0.0354709 |
| OGA | O-GlcNAcase | 0.0350779 |
| STC2 | stanniocalcin 2 | 0.0332786 |
| RPL4 | ribosomal protein L4 | 0.0328654 |
| PRRC2C | proline-rich coiled-coil 2C | 0.03273 |
| ABTB2 | ankyrin repeat and BTB (POZ) domain containing 2 | 0.0326694 |
| VIM | vimentin | 0.0325649 |
| KTN1 | kinectin 1 (kinesin receptor) | 0.0319755 |
| ANGPTL4 | angiopoietin-like 4 | 0.031088 |
| AKAP12 | A kinase (PRKA) anchor protein 12 | 0.0309217 |
| BIRC3 | baculoviral IAP repeat containing 3 | 0.030324 |
| TAX1BP1 | Tax1 (human T-cell leukemia virus type I) binding protein 1 | 0.0300556 |
| PDGFA | platelet-derived growth factor alpha polypeptide | 0.0295755 |
| RPL11 | ribosomal protein L11 | 0.0292653 |
| EDN1 | endothelin 1 | 0.0289181 |
| SESN2 | sestrin 2 | 0.0286994 |
| P4HB | prolyl 4-hydroxylase, beta polypeptide | 0.0285962 |
| CSNK1A1 | casein kinase 1, alpha 1 | 0.0282778 |
| YBX1 | Y box binding protein 1 | 0.0281684 |
| HLA-A | major histocompatibility complex, class I, A | 0.027983 |
| DSCAM | Down syndrome cell adhesion molecule | 0.0278488 |
| LRRC49 | leucine rich repeat containing 49 | 0.0276382 |
| RABGEF1 | RAB guanine nucleotide exchange factor (GEF) 1 | 0.0276138 |
| PPFIA1 | protein tyrosine phosphatase, receptor type, f polypeptide (PTPRF), interacting protein (liprin), alpha 1 | 0.0274609 |
| MAP1B | microtubule-associated protein 1B | 0.026696 |
| B2M | beta-2-microglobulin | 0.0265366 |
| RPL26 | ribosomal protein L26 | 0.026295 |
| RPS8 | ribosomal protein S8 | 0.0260876 |
| EPRS1 | glutamyl-prolyl-tRNA synthetase 1 | 0.0259775 |
| ARIH1 | ariadne RBR E3 ubiquitin protein ligase 1 | 0.0258985 |
| ENO1 | enolase 1, (alpha) | 0.0257011 |
| LIMA1 | LIM domain and actin binding 1 | 0.0255498 |
| HDAC9 | histone deacetylase 9 | 0.0252487 |
| BLZF1 | basic leucine zipper nuclear factor 1 | 0.0252195 |
| HLA-B | major histocompatibility complex, class I, B | 0.025145 |
| RSU1 | Ras suppressor protein 1 | 0.025069 |
| HDLBP | high density lipoprotein binding protein | 0.0250608 |
| COG5 | component of oligomeric golgi complex 5 | 0.0249712 |
| EIF5B | eukaryotic translation initiation factor 5B | 0.0248811 |
| RPL5 | ribosomal protein L5 | 0.0245203 |
| AKAP9 | A kinase (PRKA) anchor protein 9 | 0.0244135 |
| NFAT5 | nuclear factor of activated T-cells 5, tonicity-responsive | 0.0243792 |
| ARPC2 | actin related protein 2/3 complex, subunit 2, 34kDa | 0.0241886 |
| MCTP1 | multiple C2 domains, transmembrane 1 | 0.0238228 |
| JAK1 | Janus kinase 1 | 0.0237467 |
| ATF4 | activating transcription factor 4 | 0.0237241 |
| SCFD1 | sec1 family domain containing 1 | 0.0235454 |
| TMSB10 | thymosin beta 10 | 0.023464 |
| JUN | jun proto-oncogene | 0.0232535 |
| TAF1D | TATA box binding protein (TBP)-associated factor, RNA polymerase I, D, 41kDa | 0.0230788 |
| CAPZB | capping protein (actin filament) muscle Z-line, beta | 0.0230758 |
| PKM | pyruvate kinase, muscle | 0.0229951 |
| Symbol | Name | Standardized Value |
|---|---|---|
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.134335 |
| AHNAK | AHNAK nucleoprotein | -0.117325 |
| RPS16 | ribosomal protein S16 | -0.102842 |
| CD44 | CD44 molecule (Indian blood group) | -0.084911 |
| SLC35F3 | solute carrier family 35, member F3 | -0.0703903 |
| DST | dystonin | -0.0672384 |
| FBL | fibrillarin | -0.0655077 |
| PTPN14 | protein tyrosine phosphatase, non-receptor type 14 | -0.0612062 |
| ACTN4 | actinin, alpha 4 | -0.0606724 |
| KCNQ5 | potassium channel, voltage gated KQT-like subfamily Q, member 5 | -0.0584296 |
| MYOF | myoferlin | -0.0581691 |
| TBC1D8 | TBC1 domain family, member 8 (with GRAM domain) | -0.0559063 |
| EEPD1 | endonuclease/exonuclease/phosphatase family domain containing 1 | -0.0462605 |
| ASAP1 | ArfGAP with SH3 domain, ankyrin repeat and PH domain 1 | -0.0424951 |
| AFAP1 | actin filament associated protein 1 | -0.0411118 |
| SBF2 | SET binding factor 2 | -0.0405589 |
| EHBP1 | EH domain binding protein 1 | -0.0388771 |
| SDK1 | sidekick cell adhesion molecule 1 | -0.0388295 |
| EGFR | epidermal growth factor receptor | -0.0379353 |
| IGF1R | insulin-like growth factor 1 receptor | -0.0366991 |
| UBASH3B | ubiquitin associated and SH3 domain containing B | -0.0344114 |
| THSD4 | thrombospondin, type I, domain containing 4 | -0.0341485 |
| TANC2 | tetratricopeptide repeat, ankyrin repeat and coiled-coil containing 2 | -0.0341051 |
| TMEM123 | transmembrane protein 123 | -0.0329715 |
| IMMP2L | IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) | -0.0308426 |
| UTRN | utrophin | -0.030106 |
| EIF4G2 | eukaryotic translation initiation factor 4 gamma, 2 | -0.0299847 |
| RNF220 | ring finger protein 220 | -0.0292386 |
| PTK2 | protein tyrosine kinase 2 | -0.0289718 |
| SFTPA2 | surfactant protein A2 | -0.0287553 |
| ANXA2 | annexin A2 | -0.0285206 |
| ZNF780B | zinc finger protein 780B | -0.0267884 |
| SEMA4B | sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4B | -0.0265474 |
| MACF1 | microtubule-actin crosslinking factor 1 | -0.0264414 |
| HMGA2 | high mobility group AT-hook 2 | -0.0257621 |
| TCF12 | transcription factor 12 | -0.025753 |
| CARD18 | caspase recruitment domain family, member 18 | -0.0257002 |
| MYO10 | myosin X | -0.0254751 |
| ARID1B | AT rich interactive domain 1B (SWI1-like) | -0.0254361 |
| NT5E | 5'-nucleotidase, ecto (CD73) | -0.0254105 |
| MEF2A | myocyte enhancer factor 2A | -0.0248363 |
| TNS3 | tensin 3 | -0.0247067 |
| CDK6 | cyclin-dependent kinase 6 | -0.0243387 |
| TBL1XR1 | transducin (beta)-like 1 X-linked receptor 1 | -0.0242027 |
| UACA | uveal autoantigen with coiled-coil domains and ankyrin repeats | -0.0241915 |
| PHLDA1 | pleckstrin homology-like domain, family A, member 1 | -0.0236892 |
| ADGRG6 | adhesion G protein-coupled receptor G6 | -0.0235423 |
| ACTG1 | actin gamma 1 | -0.0230375 |
| EXOC4 | exocyst complex component 4 | -0.0224509 |
| LARP1 | La ribonucleoprotein domain family, member 1 | -0.0220314 |
| EFNA5 | ephrin-A5 | -0.0219604 |
| PITPNC1 | phosphatidylinositol transfer protein, cytoplasmic 1 | -0.0218138 |
| CENPF | centromere protein F, 350/400kDa | -0.021774 |
| HPCAL1 | hippocalcin-like 1 | -0.021304 |
| LPP | LIM domain containing preferred translocation partner in lipoma | -0.0211652 |
| NHSL1 | NHS-like 1 | -0.021099 |
| AGAP1 | ArfGAP with GTPase domain, ankyrin repeat and PH domain 1 | -0.021006 |
| SMYD3 | SET and MYND domain containing 3 | -0.0204602 |
| TUBB | tubulin, beta class I | -0.0203264 |
| DDAH1 | dimethylarginine dimethylaminohydrolase 1 | -0.0202914 |
| KMT2A | lysine (K)-specific methyltransferase 2A | -0.0202439 |
| MED13L | mediator complex subunit 13-like | -0.0201953 |
| BMERB1 | bMERB domain containing 1 | -0.0201487 |
| TXNRD1 | thioredoxin reductase 1 | -0.0200504 |
| ANTXR2 | anthrax toxin receptor 2 | -0.0200149 |
| PHF14 | PHD finger protein 14 | -0.0197001 |
| ATG7 | autophagy related 7 | -0.0194084 |
| ARHGEF28 | Rho guanine nucleotide exchange factor (GEF) 28 | -0.0193527 |
| CTSD | cathepsin D | -0.0191808 |
| TBC1D5 | TBC1 domain family, member 5 | -0.0191543 |
| APP | amyloid beta (A4) precursor protein | -0.018838 |
| NFIA | nuclear factor I/A | -0.018627 |
| RPLP0 | ribosomal protein, large, P0 | -0.0186174 |
| RHPN2 | rhophilin, Rho GTPase binding protein 2 | -0.0185496 |
| ARB2A | ARB2 cotranscriptional regulator A | -0.0184325 |
| CDKAL1 | CDK5 regulatory subunit associated protein 1-like 1 | -0.0182608 |
| PRSS23 | protease, serine, 23 | -0.0182562 |
| NXN | nucleoredoxin | -0.0181482 |
| ZZZ3 | zinc finger, ZZ-type containing 3 | -0.0180795 |
| SYNCRIP | synaptotagmin binding, cytoplasmic RNA interacting protein | -0.018063 |
| TUBA1B | tubulin, alpha 1b | -0.0180627 |
| DIAPH2 | diaphanous-related formin 2 | -0.0179059 |
| CD109 | CD109 molecule | -0.0178229 |
| FAT1 | FAT atypical cadherin 1 | -0.0177885 |
| IGF2R | insulin-like growth factor 2 receptor | -0.0177508 |
| YWHAQ | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, theta | -0.0177311 |
| RPTOR | regulatory associated protein of MTOR, complex 1 | -0.0176737 |
| CDK19 | cyclin-dependent kinase 19 | -0.0175125 |
| TRIO | trio Rho guanine nucleotide exchange factor | -0.0175029 |
| PTPRK | protein tyrosine phosphatase, receptor type, K | -0.0174045 |
| STXBP5 | syntaxin binding protein 5 (tomosyn) | -0.0172763 |
| DOCK5 | dedicator of cytokinesis 5 | -0.0171564 |
| RERE | arginine-glutamic acid dipeptide (RE) repeats | -0.0169847 |
| ANTXR1 | anthrax toxin receptor 1 | -0.0168647 |
| CEP170 | centrosomal protein 170kDa | -0.0168403 |
| MAP3K20 | mitogen-activated protein kinase kinase kinase 20 | -0.0168225 |
| VPS13B | vacuolar protein sorting 13 homolog B (yeast) | -0.0163769 |
| DENND5B | DENN/MADD domain containing 5B | -0.0163365 |
| REV3L | REV3-like, polymerase (DNA directed), zeta, catalytic subunit | -0.0162948 |
| LRPPRC | leucine-rich pentatricopeptide repeat containing | -0.0161863 |
