| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | SBI-0640756 perturbation in RPMI-7951 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the SBI-0640756_RPMI-7951 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| EGR1 | early growth response 1 | 0.148239 |
| STC1 | stanniocalcin 1 | 0.145369 |
| FTL | ferritin, light polypeptide | 0.12594 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | 0.119861 |
| B2M | beta-2-microglobulin | 0.118602 |
| HLA-B | major histocompatibility complex, class I, B | 0.113807 |
| SPARC | secreted protein, acidic, cysteine-rich (osteonectin) | 0.110586 |
| PPP1R15A | protein phosphatase 1, regulatory subunit 15A | 0.103531 |
| IGFBP3 | insulin-like growth factor binding protein 3 | 0.0901984 |
| LOC102724023 | ES1 protein homolog, mitochondrial | 0.0760703 |
| ANGPTL4 | angiopoietin-like 4 | 0.0719668 |
| SQSTM1 | sequestosome 1 | 0.0704578 |
| ENO1 | enolase 1, (alpha) | 0.0701418 |
| FTH1 | ferritin, heavy polypeptide 1 | 0.0623405 |
| RND3 | Rho family GTPase 3 | 0.0608173 |
| CDH13 | cadherin 13 | 0.0606841 |
| IFI6 | interferon, alpha-inducible protein 6 | 0.0592681 |
| LRRFIP1 | leucine rich repeat (in FLII) interacting protein 1 | 0.0566757 |
| ARL4C | ADP-ribosylation factor-like 4C | 0.0551456 |
| CEMIP | cell migration inducing protein, hyaluronan binding | 0.0543354 |
| AKAP12 | A kinase (PRKA) anchor protein 12 | 0.0523969 |
| BHLHE40 | basic helix-loop-helix family, member e40 | 0.0500686 |
| IL6 | interleukin 6 | 0.048246 |
| MMP2 | matrix metallopeptidase 2 | 0.0468498 |
| HLA-A | major histocompatibility complex, class I, A | 0.0458572 |
| HDAC9 | histone deacetylase 9 | 0.0411933 |
| SP100 | SP100 nuclear antigen | 0.0406096 |
| ABL2 | ABL proto-oncogene 2, non-receptor tyrosine kinase | 0.0352517 |
| IFI44L | interferon-induced protein 44-like | 0.0352227 |
| ADM | adrenomedullin | 0.0340336 |
| ITPR1 | inositol 1,4,5-trisphosphate receptor, type 1 | 0.0338058 |
| SRRM2 | serine/arginine repetitive matrix 2 | 0.0336435 |
| CADM1 | cell adhesion molecule 1 | 0.0329958 |
| RPS12 | ribosomal protein S12 | 0.0325143 |
| HLA-C | major histocompatibility complex, class I, C | 0.0321937 |
| ETS1 | v-ets avian erythroblastosis virus E26 oncogene homolog 1 | 0.0321263 |
| RPL37A | ribosomal protein L37a | 0.0317675 |
| KCNMA1 | potassium channel, calcium activated large conductance subfamily M alpha, member 1 | 0.0312914 |
| RPS3 | ribosomal protein S3 | 0.0311241 |
| NR1D1 | nuclear receptor subfamily 1, group D, member 1 | 0.0305795 |
| TPT1 | tumor protein, translationally-controlled 1 | 0.0305762 |
| RPL26 | ribosomal protein L26 | 0.0301537 |
| FOSL1 | FOS-like antigen 1 | 0.0286299 |
| INTS6 | integrator complex subunit 6 | 0.0282426 |
| PER1 | period circadian clock 1 | 0.0282229 |
| JUN | jun proto-oncogene | 0.0280662 |
| RPL4 | ribosomal protein L4 | 0.0279917 |
| IFITM3 | interferon induced transmembrane protein 3 | 0.0277226 |
| MMP14 | matrix metallopeptidase 14 (membrane-inserted) | 0.0275405 |
| PRRC2C | proline-rich coiled-coil 2C | 0.0274456 |
| SPTBN1 | spectrin, beta, non-erythrocytic 1 | 0.0267556 |
| IER2 | immediate early response 2 | 0.0265945 |
| KLF10 | Kruppel-like factor 10 | 0.0260306 |
| KTN1 | kinectin 1 (kinesin receptor) | 0.0260097 |
| ENO2 | enolase 2 (gamma, neuronal) | 0.0255905 |
| TLN1 | talin 1 | 0.0252336 |
| OSBPL8 | oxysterol binding protein-like 8 | 0.0251073 |
| GREM1 | gremlin 1, DAN family BMP antagonist | 0.025083 |
| HIVEP2 | human immunodeficiency virus type I enhancer binding protein 2 | 0.0249708 |
| C1S | complement component 1, s subcomponent | 0.0249204 |
| SMARCC1 | SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily c, member 1 | 0.0243711 |
| YWHAB | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, beta | 0.0239852 |
| TMSB10 | thymosin beta 10 | 0.0239831 |
| TRIO | trio Rho guanine nucleotide exchange factor | 0.0232925 |
| FBXO32 | F-box protein 32 | 0.0229392 |
| ZSWIM6 | zinc finger, SWIM-type containing 6 | 0.0226764 |
| PRPF4B | pre-mRNA processing factor 4B | 0.0225909 |
| RPL36 | ribosomal protein L36 | 0.0224459 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | 0.0223776 |
| VEGFA | vascular endothelial growth factor A | 0.0223157 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | 0.0219909 |
| EIF4G3 | eukaryotic translation initiation factor 4 gamma, 3 | 0.0218979 |
| HIVEP1 | human immunodeficiency virus type I enhancer binding protein 1 | 0.0217174 |
| PLIN2 | perilipin 2 | 0.0212973 |
| DDIT4 | DNA-damage-inducible transcript 4 | 0.0212792 |
| IRF2BP2 | interferon regulatory factor 2 binding protein 2 | 0.0212618 |
| EIF2S2 | eukaryotic translation initiation factor 2, subunit 2 beta, 38kDa | 0.0212305 |
| RPL31 | ribosomal protein L31 | 0.0210374 |
| RPS6 | ribosomal protein S6 | 0.0210206 |
| RPS17 | ribosomal protein S17 | 0.0210085 |
| MTHFD1L | methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 1-like | 0.0209278 |
| SCD | stearoyl-CoA desaturase (delta-9-desaturase) | 0.0209011 |
| SPOCK1 | sparc/osteonectin, cwcv and kazal-like domains proteoglycan (testican) 1 | 0.0205123 |
| LPCAT2 | lysophosphatidylcholine acyltransferase 2 | 0.0204622 |
| GADD45B | growth arrest and DNA-damage-inducible, beta | 0.0203761 |
| KAZN | kazrin, periplakin interacting protein | 0.0203727 |
| ITPR2 | inositol 1,4,5-trisphosphate receptor, type 2 | 0.0200957 |
| IQCB1 | IQ motif containing B1 | 0.0200845 |
| TGFBI | transforming growth factor, beta-induced, 68kDa | 0.019906 |
| ZFP36L1 | ZFP36 ring finger protein-like 1 | 0.0198145 |
| SLC38A2 | solute carrier family 38, member 2 | 0.0198001 |
| MTDH | metadherin | 0.0197896 |
| CLIP2 | CAP-GLY domain containing linker protein 2 | 0.0197029 |
| CLIP1 | CAP-GLY domain containing linker protein 1 | 0.0196497 |
| CNN3 | calponin 3, acidic | 0.0195494 |
| CAPN2 | calpain 2, (m/II) large subunit | 0.0191046 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.0190829 |
| ST3GAL6 | ST3 beta-galactoside alpha-2,3-sialyltransferase 6 | 0.0189457 |
| LYST | lysosomal trafficking regulator | 0.0187157 |
| TAX1BP1 | Tax1 (human T-cell leukemia virus type I) binding protein 1 | 0.0186382 |
| Symbol | Name | Standardized Value |
|---|---|---|
| FN1 | fibronectin 1 | -0.328854 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.16147 |
| CD44 | CD44 molecule (Indian blood group) | -0.126035 |
| FRMD4A | FERM domain containing 4A | -0.103414 |
| PGK1 | phosphoglycerate kinase 1 | -0.095588 |
| NRP1 | neuropilin 1 | -0.0841983 |
| FNDC3B | fibronectin type III domain containing 3B | -0.069486 |
| PSD3 | pleckstrin and Sec7 domain containing 3 | -0.0684331 |
| ZEB1 | zinc finger E-box binding homeobox 1 | -0.0619599 |
| PTPN14 | protein tyrosine phosphatase, non-receptor type 14 | -0.0562899 |
| CENPF | centromere protein F, 350/400kDa | -0.0550721 |
| TIMP3 | TIMP metallopeptidase inhibitor 3 | -0.0515234 |
| DCBLD2 | discoidin, CUB and LCCL domain containing 2 | -0.0496044 |
| ITGB1 | integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) | -0.0471067 |
| CTNNB1 | catenin (cadherin-associated protein), beta 1, 88kDa | -0.0447822 |
| ZNF292 | zinc finger protein 292 | -0.0436943 |
| DLG1 | discs, large homolog 1 (Drosophila) | -0.0430739 |
| SMC4 | structural maintenance of chromosomes 4 | -0.042652 |
| UBR5 | ubiquitin protein ligase E3 component n-recognin 5 | -0.0426463 |
| AFAP1 | actin filament associated protein 1 | -0.0424034 |
| TMEM178B | transmembrane protein 178B | -0.0421967 |
| SNAP25 | synaptosomal-associated protein, 25kDa | -0.0420202 |
| BRWD3 | bromodomain and WD repeat domain containing 3 | -0.041711 |
| MEF2A | myocyte enhancer factor 2A | -0.0414947 |
| NF1 | neurofibromin 1 | -0.0414413 |
| SMAD3 | SMAD family member 3 | -0.0410358 |
| MBD5 | methyl-CpG binding domain protein 5 | -0.0409569 |
| VCL | vinculin | -0.0403448 |
| ZMYND8 | zinc finger, MYND-type containing 8 | -0.0396765 |
| PALM2AKAP2 | PALM2 and AKAP2 fusion | -0.0395201 |
| WWTR1 | WW domain containing transcription regulator 1 | -0.0390655 |
| VIM | vimentin | -0.0390614 |
| DNAAF9 | dynein axonemal assembly factor 9 | -0.0382816 |
| MSN | moesin | -0.0371974 |
| STAT1 | signal transducer and activator of transcription 1, 91kDa | -0.0364224 |
| TOP2A | topoisomerase (DNA) II alpha 170kDa | -0.0364203 |
| MKI67 | marker of proliferation Ki-67 | -0.0361099 |
| MBNL1 | muscleblind-like splicing regulator 1 | -0.0358567 |
| RBPJ | recombination signal binding protein for immunoglobulin kappa J region | -0.035534 |
| TFG | TRK-fused gene | -0.0355154 |
| DSCAM | Down syndrome cell adhesion molecule | -0.0352491 |
| TPX2 | TPX2, microtubule-associated | -0.0349672 |
| MON2 | MON2 homolog (S. cerevisiae) | -0.0345896 |
| NBAS | neuroblastoma amplified sequence | -0.0345616 |
| YWHAZ | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta | -0.033849 |
| FLNB | filamin B, beta | -0.033498 |
| RNF24 | ring finger protein 24 | -0.0333631 |
| NFATC2 | nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 2 | -0.0330023 |
| SEPTIN7 | septin 7 | -0.0328482 |
| LDHA | lactate dehydrogenase A | -0.0324799 |
| MYH9 | myosin, heavy chain 9, non-muscle | -0.0321109 |
| TNS3 | tensin 3 | -0.0320931 |
| LRRFIP2 | leucine rich repeat (in FLII) interacting protein 2 | -0.0316652 |
| SCLT1 | sodium channel and clathrin linker 1 | -0.0313933 |
| ELL2 | elongation factor, RNA polymerase II, 2 | -0.0309358 |
| COPA | coatomer protein complex, subunit alpha | -0.0305299 |
| HMGA2 | high mobility group AT-hook 2 | -0.0303615 |
| PITPNC1 | phosphatidylinositol transfer protein, cytoplasmic 1 | -0.0302754 |
| ANLN | anillin, actin binding protein | -0.0302529 |
| ANKRD11 | ankyrin repeat domain 11 | -0.0299261 |
| ADNP | activity-dependent neuroprotector homeobox | -0.0296421 |
| COL6A1 | collagen, type VI, alpha 1 | -0.0296402 |
| DIAPH3 | diaphanous-related formin 3 | -0.0293207 |
| ANKRD17 | ankyrin repeat domain 17 | -0.0291548 |
| ZFAND6 | zinc finger, AN1-type domain 6 | -0.0290448 |
| TFPI2 | tissue factor pathway inhibitor 2 | -0.0289674 |
| TGM2 | transglutaminase 2 | -0.0289566 |
| PEAK1 | pseudopodium-enriched atypical kinase 1 | -0.0289484 |
| NPAS2 | neuronal PAS domain protein 2 | -0.0286258 |
| UACA | uveal autoantigen with coiled-coil domains and ankyrin repeats | -0.028613 |
| COL4A2 | collagen, type IV, alpha 2 | -0.0285831 |
| TNNC1 | troponin C type 1 (slow) | -0.0284801 |
| ESYT2 | extended synaptotagmin-like protein 2 | -0.0281701 |
| ASPM | asp (abnormal spindle) homolog, microcephaly associated (Drosophila) | -0.0278504 |
| SBF2 | SET binding factor 2 | -0.02782 |
| KLF7 | Kruppel-like factor 7 (ubiquitous) | -0.0276757 |
| ICAM1 | intercellular adhesion molecule 1 | -0.0274253 |
| MINDY2 | MINDY lysine 48 deubiquitinase 2 | -0.0272126 |
| MX2 | MX dynamin-like GTPase 2 | -0.0270527 |
| RBM39 | RNA binding motif protein 39 | -0.0270022 |
| TPM1 | tropomyosin 1 (alpha) | -0.026994 |
| KDM4C | lysine (K)-specific demethylase 4C | -0.0268762 |
| CALU | calumenin | -0.0268405 |
| ANKRD28 | ankyrin repeat domain 28 | -0.0267776 |
| FKBP1A | FK506 binding protein 1A, 12kDa | -0.0266065 |
| CAV1 | caveolin 1, caveolae protein, 22kDa | -0.0264864 |
| HMBOX1 | homeobox containing 1 | -0.0264154 |
| MED13L | mediator complex subunit 13-like | -0.0263572 |
| MKLN1 | muskelin 1, intracellular mediator containing kelch motifs | -0.0262491 |
| CHSY1 | chondroitin sulfate synthase 1 | -0.0261515 |
| SSH1 | slingshot protein phosphatase 1 | -0.0260924 |
| ANXA2 | annexin A2 | -0.0260252 |
| SH3RF3 | SH3 domain containing ring finger 3 | -0.0260126 |
| SYNCRIP | synaptotagmin binding, cytoplasmic RNA interacting protein | -0.0259897 |
| ACTN4 | actinin, alpha 4 | -0.0259385 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | -0.0259293 |
| SEC31A | SEC31 homolog A (S. cerevisiae) | -0.0256651 |
| PCBP3 | poly(rC) binding protein 3 | -0.0253445 |
| CAPZB | capping protein (actin filament) muscle Z-line, beta | -0.0252061 |
| FMNL2 | formin-like 2 | -0.0251998 |
