| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | SBI-0640756 perturbation in SNU-1 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the SBI-0640756_SNU-1 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| ENO2 | enolase 2 (gamma, neuronal) | 0.0676605 |
| GOLGA4 | golgin A4 | 0.0588282 |
| RPS12 | ribosomal protein S12 | 0.0465483 |
| ANKRD12 | ankyrin repeat domain 12 | 0.0448369 |
| FTL | ferritin, light polypeptide | 0.0418507 |
| RPS3 | ribosomal protein S3 | 0.0388016 |
| PRRC2C | proline-rich coiled-coil 2C | 0.0371249 |
| AKAP9 | A kinase (PRKA) anchor protein 9 | 0.0353513 |
| SDK1 | sidekick cell adhesion molecule 1 | 0.0336416 |
| ANK2 | ankyrin 2, neuronal | 0.0333052 |
| HIVEP2 | human immunodeficiency virus type I enhancer binding protein 2 | 0.0314461 |
| FAF1 | Fas (TNFRSF6) associated factor 1 | 0.029069 |
| APLP2 | amyloid beta (A4) precursor-like protein 2 | 0.0282672 |
| MBD5 | methyl-CpG binding domain protein 5 | 0.0273155 |
| BACH2 | BTB and CNC homology 1, basic leucine zipper transcription factor 2 | 0.0266013 |
| GARS1 | glycyl-tRNA synthetase 1 | 0.0259494 |
| RPL13A | ribosomal protein L13a | 0.0254906 |
| RBPJ | recombination signal binding protein for immunoglobulin kappa J region | 0.0251032 |
| EIF2S2 | eukaryotic translation initiation factor 2, subunit 2 beta, 38kDa | 0.0246701 |
| CTNND1 | catenin (cadherin-associated protein), delta 1 | 0.024474 |
| GYS1 | glycogen synthase 1 (muscle) | 0.0231316 |
| SP100 | SP100 nuclear antigen | 0.0226973 |
| RPL4 | ribosomal protein L4 | 0.0226154 |
| RPL37A | ribosomal protein L37a | 0.022405 |
| ANKRD11 | ankyrin repeat domain 11 | 0.0222861 |
| HDAC9 | histone deacetylase 9 | 0.0222758 |
| GCC2 | GRIP and coiled-coil domain containing 2 | 0.0218552 |
| TTC3 | tetratricopeptide repeat domain 3 | 0.0214614 |
| MED13L | mediator complex subunit 13-like | 0.021393 |
| ID3 | inhibitor of DNA binding 3, dominant negative helix-loop-helix protein | 0.0208269 |
| PSAT1 | phosphoserine aminotransferase 1 | 0.0208248 |
| WNK1 | WNK lysine deficient protein kinase 1 | 0.0201337 |
| ANKHD1 | ankyrin repeat and KH domain containing 1 | 0.0199284 |
| RAB6A | RAB6A, member RAS oncogene family | 0.0197621 |
| ERC1 | ELKS/RAB6-interacting/CAST family member 1 | 0.0197313 |
| PITPNC1 | phosphatidylinositol transfer protein, cytoplasmic 1 | 0.0193204 |
| AHI1 | Abelson helper integration site 1 | 0.0192666 |
| HNRNPA1 | heterogeneous nuclear ribonucleoprotein A1 | 0.019192 |
| THOC2 | THO complex 2 | 0.0191531 |
| RALGAPA2 | Ral GTPase activating protein, alpha subunit 2 (catalytic) | 0.0190169 |
| TCF12 | transcription factor 12 | 0.0189674 |
| UBXN4 | UBX domain protein 4 | 0.0188474 |
| AKAP12 | A kinase (PRKA) anchor protein 12 | 0.0188343 |
| EPB41 | erythrocyte membrane protein band 4.1 | 0.0185057 |
| RPL36 | ribosomal protein L36 | 0.0183294 |
| BOD1L1 | biorientation of chromosomes in cell division 1-like 1 | 0.0182172 |
| ALMS1 | Alstrom syndrome protein 1 | 0.0181237 |
| LUC7L3 | LUC7-like 3 (S. cerevisiae) | 0.0180524 |
| RIC1 | RAB6A GEF complex partner 1 | 0.0178388 |
| NUP58 | nucleoporin 58 | 0.0177372 |
| WSB1 | WD repeat and SOCS box containing 1 | 0.0177341 |
| HNRNPH1 | heterogeneous nuclear ribonucleoprotein H1 (H) | 0.0175776 |
| TET2 | tet methylcytosine dioxygenase 2 | 0.0171755 |
| PDE7A | phosphodiesterase 7A | 0.0170906 |
| FAM162A | family with sequence similarity 162, member A | 0.0170884 |
| NAMPT | nicotinamide phosphoribosyltransferase | 0.0170602 |
| MEF2A | myocyte enhancer factor 2A | 0.0170362 |
| AP2B1 | adaptor-related protein complex 2, beta 1 subunit | 0.0170327 |
| UIMC1 | ubiquitin interaction motif containing 1 | 0.0170126 |
| NACA | nascent polypeptide-associated complex alpha subunit | 0.0169936 |
| ADGRA3 | adhesion G protein-coupled receptor A3 | 0.0169754 |
| METTL15 | methyltransferase like 15 | 0.0169411 |
| PER1 | period circadian clock 1 | 0.0167606 |
| KDELR1 | KDEL (Lys-Asp-Glu-Leu) endoplasmic reticulum protein retention receptor 1 | 0.0165773 |
| SOS1 | son of sevenless homolog 1 (Drosophila) | 0.0164684 |
| TMF1 | TATA element modulatory factor 1 | 0.0163961 |
| GOSR2 | golgi SNAP receptor complex member 2 | 0.0163683 |
| PELP1 | proline, glutamate and leucine rich protein 1 | 0.0163061 |
| DOCK4 | dedicator of cytokinesis 4 | 0.0162113 |
| MYO19 | myosin XIX | 0.0161103 |
| MGAT5 | mannosyl (alpha-1,6-)-glycoprotein beta-1,6-N-acetyl-glucosaminyltransferase | 0.0160579 |
| CMIP | c-Maf inducing protein | 0.01602 |
| SYF2 | SYF2 pre-mRNA-splicing factor | 0.0159957 |
| PATJ | PATJ crumbs cell polarity complex component | 0.015995 |
| MAP2K1 | mitogen-activated protein kinase kinase 1 | 0.0159188 |
| RPL17-C18ORF32 | RPL17-C18orf32 readthrough | 0.0158148 |
| DDIT4 | DNA-damage-inducible transcript 4 | 0.0156874 |
| SET | SET nuclear proto-oncogene | 0.0156838 |
| JMJD1C | jumonji domain containing 1C | 0.0155832 |
| ERBIN | erbb2 interacting protein | 0.0155108 |
| PTK2 | protein tyrosine kinase 2 | 0.0154902 |
| RYBP | RING1 and YY1 binding protein | 0.0154593 |
| IGF2R | insulin-like growth factor 2 receptor | 0.0153744 |
| NFE2L1 | nuclear factor, erythroid 2-like 1 | 0.0152719 |
| GIGYF2 | GRB10 interacting GYF protein 2 | 0.0152262 |
| OTUD7B | OTU deubiquitinase 7B | 0.0151742 |
| UBA6 | ubiquitin-like modifier activating enzyme 6 | 0.0151061 |
| GPT2 | glutamic pyruvate transaminase (alanine aminotransferase) 2 | 0.0150128 |
| PALS2 | protein associated with LIN7 2, MAGUK p55 family member | 0.014994 |
| CXCL8 | chemokine (C-X-C motif) ligand 8 | 0.0149852 |
| PTEN | phosphatase and tensin homolog | 0.0149627 |
| UBE2E1 | ubiquitin-conjugating enzyme E2E 1 | 0.0149558 |
| TAX1BP1 | Tax1 (human T-cell leukemia virus type I) binding protein 1 | 0.0148898 |
| MTREX | Mtr4 exosome RNA helicase | 0.0148497 |
| RPS18 | ribosomal protein S18 | 0.0147127 |
| SLC7A11 | solute carrier family 7 (anionic amino acid transporter light chain, xc- system), member 11 | 0.0146931 |
| KCNMA1 | potassium channel, calcium activated large conductance subfamily M alpha, member 1 | 0.0146454 |
| INSIG1 | insulin induced gene 1 | 0.0145866 |
| CRYBG3 | beta-gamma crystallin domain containing 3 | 0.0145315 |
| EIF5B | eukaryotic translation initiation factor 5B | 0.0144901 |
| Symbol | Name | Standardized Value |
|---|---|---|
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.324145 |
| AHNAK | AHNAK nucleoprotein | -0.189622 |
| VCL | vinculin | -0.123677 |
| CPED1 | cadherin-like and PC-esterase domain containing 1 | -0.118156 |
| PTMA | prothymosin, alpha | -0.11417 |
| NFAT5 | nuclear factor of activated T-cells 5, tonicity-responsive | -0.104442 |
| ADAM10 | ADAM metallopeptidase domain 10 | -0.102894 |
| B3GALT1 | UDP-Gal:betaGlcNAc beta 1,3-galactosyltransferase, polypeptide 1 | -0.0967391 |
| PDE4B | phosphodiesterase 4B, cAMP-specific | -0.0967346 |
| EGFR | epidermal growth factor receptor | -0.0934801 |
| INPP4B | inositol polyphosphate-4-phosphatase, type II, 105kDa | -0.0904183 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.0880024 |
| TMSB4X | thymosin beta 4, X-linked | -0.0875042 |
| BMP10 | bone morphogenetic protein 10 | -0.0834515 |
| ZEB1 | zinc finger E-box binding homeobox 1 | -0.0814044 |
| TNFRSF11B | tumor necrosis factor receptor superfamily, member 11b | -0.077193 |
| DLG1 | discs, large homolog 1 (Drosophila) | -0.0754161 |
| EML4 | echinoderm microtubule associated protein like 4 | -0.0728505 |
| TJP1 | tight junction protein 1 | -0.0727217 |
| GLI3 | GLI family zinc finger 3 | -0.0725625 |
| PKM | pyruvate kinase, muscle | -0.0704085 |
| PDE4D | phosphodiesterase 4D, cAMP-specific | -0.0641547 |
| ACTG1 | actin gamma 1 | -0.0627962 |
| GLI2 | GLI family zinc finger 2 | -0.0625235 |
| ECT2 | epithelial cell transforming 2 | -0.0625038 |
| NPAS2 | neuronal PAS domain protein 2 | -0.0619454 |
| ANXA1 | annexin A1 | -0.0617903 |
| SLC38A2 | solute carrier family 38, member 2 | -0.0610758 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.0608161 |
| MYO5C | myosin VC | -0.0601414 |
| CYB5B | cytochrome b5 type B (outer mitochondrial membrane) | -0.0578442 |
| FLNB | filamin B, beta | -0.0575429 |
| CITED2 | Cbp/p300-interacting transactivator, with Glu/Asp-rich carboxy-terminal domain, 2 | -0.0560418 |
| DPYD | dihydropyrimidine dehydrogenase | -0.0555328 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.0553954 |
| NCEH1 | neutral cholesterol ester hydrolase 1 | -0.0551859 |
| NBEA | neurobeachin | -0.0545051 |
| RHOA | ras homolog family member A | -0.0532952 |
| MKI67 | marker of proliferation Ki-67 | -0.0526941 |
| LPP | LIM domain containing preferred translocation partner in lipoma | -0.0514332 |
| EZR | ezrin | -0.0491035 |
| RPL34 | ribosomal protein L34 | -0.0486855 |
| ARL4C | ADP-ribosylation factor-like 4C | -0.0475181 |
| RPL7A | ribosomal protein L7a | -0.0464754 |
| HSPD1 | heat shock 60kDa protein 1 (chaperonin) | -0.0464738 |
| CACNB4 | calcium channel, voltage-dependent, beta 4 subunit | -0.0454798 |
| EBNA1BP2 | EBNA1 binding protein 2 | -0.0450067 |
| S100A10 | S100 calcium binding protein A10 | -0.0434619 |
| TEAD1 | TEA domain family member 1 (SV40 transcriptional enhancer factor) | -0.0422346 |
| FOXP1 | forkhead box P1 | -0.0416226 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | -0.0416222 |
| TRERF1 | transcriptional regulating factor 1 | -0.0408606 |
| ANLN | anillin, actin binding protein | -0.0408282 |
| EEF2 | eukaryotic translation elongation factor 2 | -0.0404841 |
| CENPE | centromere protein E, 312kDa | -0.0401857 |
| TOP2A | topoisomerase (DNA) II alpha 170kDa | -0.0400688 |
| AGAP1 | ArfGAP with GTPase domain, ankyrin repeat and PH domain 1 | -0.0399398 |
| EEF1A1 | eukaryotic translation elongation factor 1 alpha 1 | -0.0398688 |
| MICAL2 | microtubule associated monooxygenase, calponin and LIM domain containing 2 | -0.0394346 |
| MYOF | myoferlin | -0.0391924 |
| MTHFD1L | methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 1-like | -0.0386556 |
| CCND1 | cyclin D1 | -0.0376461 |
| CENPF | centromere protein F, 350/400kDa | -0.0369681 |
| BMP2K | BMP2 inducible kinase | -0.036364 |
| RBMS3 | RNA binding motif, single stranded interacting protein 3 | -0.0358357 |
| EFNA5 | ephrin-A5 | -0.0356633 |
| ARL6IP1 | ADP-ribosylation factor-like 6 interacting protein 1 | -0.0354524 |
| TTC28 | tetratricopeptide repeat domain 28 | -0.035271 |
| SMNDC1 | survival motor neuron domain containing 1 | -0.0351657 |
| HSPB1 | heat shock 27kDa protein 1 | -0.0349597 |
| SMC4 | structural maintenance of chromosomes 4 | -0.0347523 |
| LDHA | lactate dehydrogenase A | -0.0347455 |
| HSPH1 | heat shock 105kDa/110kDa protein 1 | -0.0347323 |
| HNRNPU | heterogeneous nuclear ribonucleoprotein U (scaffold attachment factor A) | -0.0346679 |
| ALDH3A2 | aldehyde dehydrogenase 3 family, member A2 | -0.0345511 |
| EVI5 | ecotropic viral integration site 5 | -0.03434 |
| GALNT5 | polypeptide N-acetylgalactosaminyltransferase 5 | -0.0343113 |
| HSPA8 | heat shock 70kDa protein 8 | -0.0338889 |
| MINDY2 | MINDY lysine 48 deubiquitinase 2 | -0.0335767 |
| PDE7B | phosphodiesterase 7B | -0.0331827 |
| EIF4G2 | eukaryotic translation initiation factor 4 gamma, 2 | -0.0325899 |
| YWHAZ | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta | -0.0324781 |
| POTEF | POTE ankyrin domain family, member F | -0.0322256 |
| TPX2 | TPX2, microtubule-associated | -0.0319135 |
| RPS25 | ribosomal protein S25 | -0.0318698 |
| HJURP | Holliday junction recognition protein | -0.0316663 |
| GNB1 | guanine nucleotide binding protein (G protein), beta polypeptide 1 | -0.0316017 |
| PPM1L | protein phosphatase, Mg2+/Mn2+ dependent, 1L | -0.0314798 |
| RPS8 | ribosomal protein S8 | -0.0314116 |
| CALM2 | calmodulin 2 (phosphorylase kinase, delta) | -0.0313607 |
| SERPINB1 | serpin peptidase inhibitor, clade B (ovalbumin), member 1 | -0.0313422 |
| RTN4 | reticulon 4 | -0.0310906 |
| DIAPH3 | diaphanous-related formin 3 | -0.0309092 |
| SLC1A3 | solute carrier family 1 (glial high affinity glutamate transporter), member 3 | -0.030897 |
| ASPM | asp (abnormal spindle) homolog, microcephaly associated (Drosophila) | -0.0307643 |
| MBNL1 | muscleblind-like splicing regulator 1 | -0.0307294 |
| IRF2BP2 | interferon regulatory factor 2 binding protein 2 | -0.0297762 |
| SPTAN1 | spectrin, alpha, non-erythrocytic 1 | -0.029588 |
| PRELID2 | PRELI domain containing 2 | -0.029543 |
| S100A9 | S100 calcium binding protein A9 | -0.0294307 |
