| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | SBI-0640756 perturbation in SNU-423 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the SBI-0640756_SNU-423 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.142859 |
| STC1 | stanniocalcin 1 | 0.126413 |
| RPS12 | ribosomal protein S12 | 0.109322 |
| GPC6 | glypican 6 | 0.101037 |
| FTL | ferritin, light polypeptide | 0.0900329 |
| VIM | vimentin | 0.0852128 |
| OGA | O-GlcNAcase | 0.0798333 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | 0.0735212 |
| PLIN2 | perilipin 2 | 0.071789 |
| LDHA | lactate dehydrogenase A | 0.0599081 |
| DDIT4 | DNA-damage-inducible transcript 4 | 0.05884 |
| MXI1 | MAX interactor 1, dimerization protein | 0.0559077 |
| SPTBN1 | spectrin, beta, non-erythrocytic 1 | 0.0552941 |
| ANKRD1 | ankyrin repeat domain 1 (cardiac muscle) | 0.0552693 |
| BRD2 | bromodomain containing 2 | 0.0550944 |
| RPS3 | ribosomal protein S3 | 0.0543345 |
| PGK1 | phosphoglycerate kinase 1 | 0.0534839 |
| NDRG1 | N-myc downstream regulated 1 | 0.051603 |
| ENO1 | enolase 1, (alpha) | 0.0510353 |
| AKAP12 | A kinase (PRKA) anchor protein 12 | 0.0508288 |
| IGFBP3 | insulin-like growth factor binding protein 3 | 0.049564 |
| RPL37A | ribosomal protein L37a | 0.0481567 |
| ZNF292 | zinc finger protein 292 | 0.0455967 |
| PTMA | prothymosin, alpha | 0.0445222 |
| ANKRD11 | ankyrin repeat domain 11 | 0.0418328 |
| GOLGA4 | golgin A4 | 0.04089 |
| HLA-A | major histocompatibility complex, class I, A | 0.0407885 |
| SRRM2 | serine/arginine repetitive matrix 2 | 0.0407877 |
| AKAP9 | A kinase (PRKA) anchor protein 9 | 0.0406069 |
| CTNNA1 | catenin (cadherin-associated protein), alpha 1, 102kDa | 0.0404545 |
| MAP1B | microtubule-associated protein 1B | 0.0401863 |
| IGF2R | insulin-like growth factor 2 receptor | 0.0396584 |
| G0S2 | G0/G1 switch 2 | 0.0391305 |
| STC2 | stanniocalcin 2 | 0.038307 |
| ENO2 | enolase 2 (gamma, neuronal) | 0.0382414 |
| GARS1 | glycyl-tRNA synthetase 1 | 0.0380143 |
| SH3KBP1 | SH3-domain kinase binding protein 1 | 0.0377152 |
| PFKFB3 | 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 3 | 0.0376269 |
| BNIP3 | BCL2/adenovirus E1B 19kDa interacting protein 3 | 0.0370307 |
| APLP2 | amyloid beta (A4) precursor-like protein 2 | 0.0364433 |
| PHF21A | PHD finger protein 21A | 0.0361115 |
| WSB1 | WD repeat and SOCS box containing 1 | 0.0351257 |
| PPP1R15A | protein phosphatase 1, regulatory subunit 15A | 0.0348302 |
| PRRC2C | proline-rich coiled-coil 2C | 0.0348157 |
| TLN1 | talin 1 | 0.0345908 |
| EIF1 | eukaryotic translation initiation factor 1 | 0.0345644 |
| IFI16 | interferon, gamma-inducible protein 16 | 0.0342652 |
| RPL4 | ribosomal protein L4 | 0.0338427 |
| RAI1 | retinoic acid induced 1 | 0.0338359 |
| HGS | hepatocyte growth factor-regulated tyrosine kinase substrate | 0.0330993 |
| ELL2 | elongation factor, RNA polymerase II, 2 | 0.0325733 |
| TOP1 | topoisomerase (DNA) I | 0.0320404 |
| EZR | ezrin | 0.0320132 |
| GNAS | GNAS complex locus | 0.0313756 |
| RBPJ | recombination signal binding protein for immunoglobulin kappa J region | 0.0310082 |
| NAP1L1 | nucleosome assembly protein 1-like 1 | 0.0301086 |
| IGFN1 | immunoglobulin-like and fibronectin type III domain containing 1 | 0.029641 |
| ERRFI1 | ERBB receptor feedback inhibitor 1 | 0.0296395 |
| ARFGEF3 | ARFGEF family member 3 | 0.0294902 |
| DEPP1 | DEPP autophagy regulator 1 | 0.0289397 |
| SPAG9 | sperm associated antigen 9 | 0.0287538 |
| PTPRF | protein tyrosine phosphatase, receptor type, F | 0.0287238 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | 0.0282621 |
| KTN1 | kinectin 1 (kinesin receptor) | 0.0281444 |
| RPL13A | ribosomal protein L13a | 0.0280314 |
| CLIP1 | CAP-GLY domain containing linker protein 1 | 0.0278732 |
| ZFP36L1 | ZFP36 ring finger protein-like 1 | 0.0277516 |
| CDCP1 | CUB domain containing protein 1 | 0.0276666 |
| ASPH | aspartate beta-hydroxylase | 0.0274032 |
| EIF3A | eukaryotic translation initiation factor 3, subunit A | 0.0273262 |
| RBM25 | RNA binding motif protein 25 | 0.0271716 |
| ANKRD12 | ankyrin repeat domain 12 | 0.0270683 |
| NFE2L1 | nuclear factor, erythroid 2-like 1 | 0.0269655 |
| ATF4 | activating transcription factor 4 | 0.0268303 |
| ERC2 | ELKS/RAB6-interacting/CAST family member 2 | 0.0266901 |
| ITGA2 | integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor) | 0.0266023 |
| SET | SET nuclear proto-oncogene | 0.0261935 |
| ARID5B | AT rich interactive domain 5B (MRF1-like) | 0.0257581 |
| DTNA | dystrobrevin, alpha | 0.0255558 |
| TPM3 | tropomyosin 3 | 0.0252159 |
| SMAP1 | small ArfGAP 1 | 0.0251859 |
| PCLO | piccolo presynaptic cytomatrix protein | 0.0251298 |
| SEPTIN7 | septin 7 | 0.0250962 |
| SYNJ2 | synaptojanin 2 | 0.0248646 |
| NEDD4L | neural precursor cell expressed, developmentally down-regulated 4-like, E3 ubiquitin protein ligase | 0.0247165 |
| OSBPL8 | oxysterol binding protein-like 8 | 0.0246919 |
| HMGN2 | high mobility group nucleosomal binding domain 2 | 0.024655 |
| RAB7A | RAB7A, member RAS oncogene family | 0.0246206 |
| MARCHF1 | membrane associated ring-CH-type finger 1 | 0.0245337 |
| INSIG1 | insulin induced gene 1 | 0.0244844 |
| RPL12 | ribosomal protein L12 | 0.024148 |
| SESN2 | sestrin 2 | 0.023899 |
| AFDN | afadin, adherens junction formation factor | 0.0234963 |
| DDIT3 | DNA-damage-inducible transcript 3 | 0.0234693 |
| RPL5 | ribosomal protein L5 | 0.0231496 |
| FRMPD4 | FERM and PDZ domain containing 4 | 0.0228768 |
| RACK1 | receptor for activated C kinase 1 | 0.0228703 |
| MATR3 | matrin 3 | 0.0228317 |
| KMT2C | lysine (K)-specific methyltransferase 2C | 0.0226278 |
| SON | SON DNA binding protein | 0.0222911 |
| Symbol | Name | Standardized Value |
|---|---|---|
| FN1 | fibronectin 1 | -0.182478 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.179491 |
| SOD2 | superoxide dismutase 2, mitochondrial | -0.169181 |
| FRMD4A | FERM domain containing 4A | -0.165419 |
| VCL | vinculin | -0.115822 |
| SMAD3 | SMAD family member 3 | -0.0897865 |
| BICC1 | BicC family RNA binding protein 1 | -0.0852867 |
| FNDC3B | fibronectin type III domain containing 3B | -0.0766905 |
| GLIS3 | GLIS family zinc finger 3 | -0.0755177 |
| GRIN2A | glutamate receptor, ionotropic, N-methyl D-aspartate 2A | -0.0744443 |
| EDIL3 | EGF-like repeats and discoidin I-like domains 3 | -0.0664902 |
| COL6A3 | collagen, type VI, alpha 3 | -0.0627847 |
| TNS3 | tensin 3 | -0.060653 |
| EXT1 | exostosin glycosyltransferase 1 | -0.059898 |
| AGAP1 | ArfGAP with GTPase domain, ankyrin repeat and PH domain 1 | -0.0577026 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.0537106 |
| AHNAK | AHNAK nucleoprotein | -0.0528892 |
| SERPINE1 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1 | -0.0514273 |
| DCBLD2 | discoidin, CUB and LCCL domain containing 2 | -0.0509284 |
| RPS24 | ribosomal protein S24 | -0.0500942 |
| VEGFA | vascular endothelial growth factor A | -0.0495515 |
| TMSB10 | thymosin beta 10 | -0.0483436 |
| MAML2 | mastermind-like 2 (Drosophila) | -0.0478059 |
| PLOD2 | procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2 | -0.0466849 |
| UBC | ubiquitin C | -0.0456002 |
| IL1RAPL1 | interleukin 1 receptor accessory protein-like 1 | -0.0451075 |
| CADM1 | cell adhesion molecule 1 | -0.0448868 |
| HMGA2 | high mobility group AT-hook 2 | -0.0441242 |
| ACTG1 | actin gamma 1 | -0.0439951 |
| COL1A2 | collagen, type I, alpha 2 | -0.0436503 |
| RPS23 | ribosomal protein S23 | -0.0434447 |
| IMMP2L | IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) | -0.0427034 |
| PTPRK | protein tyrosine phosphatase, receptor type, K | -0.0408299 |
| VMP1 | vacuole membrane protein 1 | -0.0397198 |
| KYNU | kynureninase | -0.0394985 |
| PHLDA1 | pleckstrin homology-like domain, family A, member 1 | -0.0394539 |
| DPYD | dihydropyrimidine dehydrogenase | -0.0392043 |
| THBS1 | thrombospondin 1 | -0.0389442 |
| ATXN1 | ataxin 1 | -0.0384706 |
| PRR16 | proline rich 16 | -0.0377212 |
| EEF1A1 | eukaryotic translation elongation factor 1 alpha 1 | -0.03702 |
| ADAM12 | ADAM metallopeptidase domain 12 | -0.0365397 |
| EGFR | epidermal growth factor receptor | -0.0362483 |
| RPL36A | ribosomal protein L36a | -0.0357796 |
| CASK | calcium/calmodulin-dependent serine protein kinase (MAGUK family) | -0.0356341 |
| NAV2 | neuron navigator 2 | -0.0355323 |
| ZBTB38 | zinc finger and BTB domain containing 38 | -0.0349529 |
| IQCJ-SCHIP1 | IQCJ-SCHIP1 readthrough | -0.0345191 |
| NAV1 | neuron navigator 1 | -0.0343003 |
| RPLP0 | ribosomal protein, large, P0 | -0.0338452 |
| TFPI | tissue factor pathway inhibitor (lipoprotein-associated coagulation inhibitor) | -0.0336681 |
| ABCA1 | ATP-binding cassette, sub-family A (ABC1), member 1 | -0.0335581 |
| PTPN14 | protein tyrosine phosphatase, non-receptor type 14 | -0.03346 |
| UBE2H | ubiquitin-conjugating enzyme E2H | -0.0324049 |
| MACF1 | microtubule-actin crosslinking factor 1 | -0.0322905 |
| SRGN | serglycin | -0.0320802 |
| TENT5A | terminal nucleotidyltransferase 5A | -0.0313578 |
| PARD3 | par-3 family cell polarity regulator | -0.03117 |
| FOXP1 | forkhead box P1 | -0.0310165 |
| IL6 | interleukin 6 | -0.0308968 |
| CITED2 | Cbp/p300-interacting transactivator, with Glu/Asp-rich carboxy-terminal domain, 2 | -0.0304979 |
| ZFAND3 | zinc finger, AN1-type domain 3 | -0.0298026 |
| MBNL1 | muscleblind-like splicing regulator 1 | -0.0296946 |
| RPL23 | ribosomal protein L23 | -0.0294437 |
| COL1A1 | collagen, type I, alpha 1 | -0.0292676 |
| FAM20C | family with sequence similarity 20, member C | -0.0288748 |
| UGCG | UDP-glucose ceramide glucosyltransferase | -0.0287598 |
| GNB1 | guanine nucleotide binding protein (G protein), beta polypeptide 1 | -0.0277935 |
| CTSD | cathepsin D | -0.0277452 |
| MYOF | myoferlin | -0.0273956 |
| MKLN1 | muskelin 1, intracellular mediator containing kelch motifs | -0.0273476 |
| TANC2 | tetratricopeptide repeat, ankyrin repeat and coiled-coil containing 2 | -0.0273058 |
| EXOC4 | exocyst complex component 4 | -0.0272304 |
| SLC4A7 | solute carrier family 4, sodium bicarbonate cotransporter, member 7 | -0.0270383 |
| DIAPH2 | diaphanous-related formin 2 | -0.0267941 |
| HLA-E | major histocompatibility complex, class I, E | -0.0265705 |
| LOXL2 | lysyl oxidase-like 2 | -0.0265323 |
| PTK2 | protein tyrosine kinase 2 | -0.0262989 |
| AKT3 | v-akt murine thymoma viral oncogene homolog 3 | -0.0259369 |
| EEF2 | eukaryotic translation elongation factor 2 | -0.0258862 |
| IGF2BP3 | insulin-like growth factor 2 mRNA binding protein 3 | -0.0258346 |
| TAPBP | TAP binding protein (tapasin) | -0.0256466 |
| SLC35F3 | solute carrier family 35, member F3 | -0.0256316 |
| BIRC3 | baculoviral IAP repeat containing 3 | -0.0251624 |
| QKI | QKI, KH domain containing, RNA binding | -0.0246522 |
| P4HB | prolyl 4-hydroxylase, beta polypeptide | -0.0246484 |
| TNIP1 | TNFAIP3 interacting protein 1 | -0.0245499 |
| CNOT1 | CCR4-NOT transcription complex, subunit 1 | -0.0245279 |
| RPS10 | ribosomal protein S10 | -0.0245215 |
| ARRDC3 | arrestin domain containing 3 | -0.0244959 |
| PAPPA | pregnancy-associated plasma protein A, pappalysin 1 | -0.0244709 |
| TUBB | tubulin, beta class I | -0.024161 |
| ITCH | itchy E3 ubiquitin protein ligase | -0.024052 |
| ASTN2 | astrotactin 2 | -0.0239917 |
| AFF4 | AF4/FMR2 family, member 4 | -0.0237754 |
| MSN | moesin | -0.0237388 |
| FMNL2 | formin-like 2 | -0.0236707 |
| ZMYND8 | zinc finger, MYND-type containing 8 | -0.0235844 |
| UTRN | utrophin | -0.0234793 |
| WTAP | Wilms tumor 1 associated protein | -0.0234647 |
