| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | SBI-0640756 perturbation in SW 900 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the SBI-0640756_SW 900 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| STC2 | stanniocalcin 2 | 0.0908168 |
| PLIN2 | perilipin 2 | 0.0880124 |
| PTGS2 | prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase) | 0.0678595 |
| NPAS2 | neuronal PAS domain protein 2 | 0.0590021 |
| SLC5A3 | solute carrier family 5 (sodium/myo-inositol cotransporter), member 3 | 0.0573391 |
| RAI14 | retinoic acid induced 14 | 0.0553345 |
| AKAP12 | A kinase (PRKA) anchor protein 12 | 0.0548132 |
| DST | dystonin | 0.0492572 |
| HIVEP2 | human immunodeficiency virus type I enhancer binding protein 2 | 0.0469824 |
| HMGA2 | high mobility group AT-hook 2 | 0.0462781 |
| ZMIZ1 | zinc finger, MIZ-type containing 1 | 0.0456808 |
| RABGEF1 | RAB guanine nucleotide exchange factor (GEF) 1 | 0.0451134 |
| HLA-B | major histocompatibility complex, class I, B | 0.0435362 |
| ASPH | aspartate beta-hydroxylase | 0.0426828 |
| FAT1 | FAT atypical cadherin 1 | 0.040042 |
| ENO1 | enolase 1, (alpha) | 0.0393472 |
| DUSP6 | dual specificity phosphatase 6 | 0.0387944 |
| EFNA5 | ephrin-A5 | 0.0375764 |
| RAB31 | RAB31, member RAS oncogene family | 0.0372381 |
| ENO2 | enolase 2 (gamma, neuronal) | 0.0347557 |
| CLIP2 | CAP-GLY domain containing linker protein 2 | 0.0346895 |
| HIPK2 | homeodomain interacting protein kinase 2 | 0.0341489 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | 0.0339054 |
| APBB2 | amyloid beta (A4) precursor protein-binding, family B, member 2 | 0.0332598 |
| CDH11 | cadherin 11, type 2, OB-cadherin (osteoblast) | 0.0328692 |
| ERRFI1 | ERBB receptor feedback inhibitor 1 | 0.0324861 |
| SLC20A1 | solute carrier family 20 (phosphate transporter), member 1 | 0.0321609 |
| ATP2B1 | ATPase, Ca++ transporting, plasma membrane 1 | 0.0315039 |
| TPI1 | triosephosphate isomerase 1 | 0.0309391 |
| PDE4D | phosphodiesterase 4D, cAMP-specific | 0.0308793 |
| KCNMA1 | potassium channel, calcium activated large conductance subfamily M alpha, member 1 | 0.0306443 |
| CYP1B1 | cytochrome P450, family 1, subfamily B, polypeptide 1 | 0.0303723 |
| KAZN | kazrin, periplakin interacting protein | 0.0301454 |
| IFI6 | interferon, alpha-inducible protein 6 | 0.0295746 |
| CALB2 | calbindin 2 | 0.029488 |
| ARFGEF1 | ADP-ribosylation factor guanine nucleotide-exchange factor 1 (brefeldin A-inhibited) | 0.0289067 |
| RASSF8 | Ras association (RalGDS/AF-6) domain family (N-terminal) member 8 | 0.0284587 |
| ATXN1 | ataxin 1 | 0.0281635 |
| AEBP2 | AE binding protein 2 | 0.0280932 |
| ANGPTL4 | angiopoietin-like 4 | 0.0279332 |
| NRG1 | neuregulin 1 | 0.0276734 |
| INTS6 | integrator complex subunit 6 | 0.0274151 |
| PCF11 | PCF11 cleavage and polyadenylation factor subunit | 0.02728 |
| VPS53 | vacuolar protein sorting 53 homolog (S. cerevisiae) | 0.0267272 |
| MYO1E | myosin IE | 0.0265232 |
| RNASE12 | ribonuclease, RNase A family, 12 (non-active) | 0.0263452 |
| KRT19 | keratin 19, type I | 0.0261657 |
| RPL37A | ribosomal protein L37a | 0.0258104 |
| MRPS6 | mitochondrial ribosomal protein S6 | 0.0256514 |
| PTPRK | protein tyrosine phosphatase, receptor type, K | 0.0254165 |
| PIK3R3 | phosphoinositide-3-kinase, regulatory subunit 3 (gamma) | 0.0252633 |
| KDM4C | lysine (K)-specific demethylase 4C | 0.0250196 |
| STC1 | stanniocalcin 1 | 0.0243905 |
| GOLGA3 | golgin A3 | 0.023721 |
| HLA-A | major histocompatibility complex, class I, A | 0.0236549 |
| SRP72 | signal recognition particle 72kDa | 0.0235949 |
| KCNK1 | potassium channel, two pore domain subfamily K, member 1 | 0.023285 |
| CAPN2 | calpain 2, (m/II) large subunit | 0.0232279 |
| ERGIC1 | endoplasmic reticulum-golgi intermediate compartment (ERGIC) 1 | 0.0232073 |
| MAML3 | mastermind-like 3 (Drosophila) | 0.0230997 |
| PCNX2 | pecanex 2 | 0.0229953 |
| TLN1 | talin 1 | 0.0226427 |
| SPIRE1 | spire-type actin nucleation factor 1 | 0.0225627 |
| ITPR1 | inositol 1,4,5-trisphosphate receptor, type 1 | 0.0225379 |
| BICD1 | bicaudal D homolog 1 (Drosophila) | 0.0224658 |
| LOXL2 | lysyl oxidase-like 2 | 0.0222798 |
| DCBLD2 | discoidin, CUB and LCCL domain containing 2 | 0.022227 |
| ITGA2 | integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor) | 0.0221928 |
| LDHA | lactate dehydrogenase A | 0.0221707 |
| WARS1 | tryptophanyl-tRNA synthetase 1 | 0.0221284 |
| ANKRD1 | ankyrin repeat domain 1 (cardiac muscle) | 0.0220865 |
| KDM6B | lysine (K)-specific demethylase 6B | 0.0219623 |
| RECQL | RecQ helicase-like | 0.0218148 |
| ANKIB1 | ankyrin repeat and IBR domain containing 1 | 0.02163 |
| RSU1 | Ras suppressor protein 1 | 0.0213761 |
| SCFD2 | sec1 family domain containing 2 | 0.0212477 |
| FBXW7 | F-box and WD repeat domain containing 7, E3 ubiquitin protein ligase | 0.0210177 |
| PON2 | paraoxonase 2 | 0.0209632 |
| GPC6 | glypican 6 | 0.0208971 |
| NSD3 | nuclear receptor binding SET domain protein 3 | 0.0208502 |
| BOD1L1 | biorientation of chromosomes in cell division 1-like 1 | 0.0207189 |
| GRB10 | growth factor receptor-bound protein 10 | 0.0206881 |
| CUX1 | cut-like homeobox 1 | 0.0205477 |
| THRB | thyroid hormone receptor, beta | 0.0203581 |
| OXR1 | oxidation resistance 1 | 0.0202992 |
| MKNK2 | MAP kinase interacting serine/threonine kinase 2 | 0.0202868 |
| EREG | epiregulin | 0.0200609 |
| CALM1 | calmodulin 1 (phosphorylase kinase, delta) | 0.020003 |
| BZW1 | basic leucine zipper and W2 domains 1 | 0.0197662 |
| LYST | lysosomal trafficking regulator | 0.0196859 |
| ZFHX3 | zinc finger homeobox 3 | 0.0193759 |
| RBPMS | RNA binding protein with multiple splicing | 0.0192528 |
| ANKRD36C | ankyrin repeat domain 36C | 0.0191796 |
| TBC1D32 | TBC1 domain family, member 32 | 0.0191204 |
| NCOR2 | nuclear receptor corepressor 2 | 0.0190315 |
| SDK1 | sidekick cell adhesion molecule 1 | 0.01902 |
| SLC30A1 | solute carrier family 30 (zinc transporter), member 1 | 0.0187832 |
| ARHGEF12 | Rho guanine nucleotide exchange factor (GEF) 12 | 0.0186773 |
| MACF1 | microtubule-actin crosslinking factor 1 | 0.0185807 |
| LOC102724023 | ES1 protein homolog, mitochondrial | 0.0184101 |
| Symbol | Name | Standardized Value |
|---|---|---|
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.441688 |
| NAMPT | nicotinamide phosphoribosyltransferase | -0.123779 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.0800958 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | -0.076421 |
| RBPJ | recombination signal binding protein for immunoglobulin kappa J region | -0.0743277 |
| CXCL8 | chemokine (C-X-C motif) ligand 8 | -0.073887 |
| CANX | calnexin | -0.0706873 |
| MT2A | metallothionein 2A | -0.0694093 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | -0.0638342 |
| PTMA | prothymosin, alpha | -0.0611235 |
| NPM1 | nucleophosmin (nucleolar phosphoprotein B23, numatrin) | -0.0565505 |
| ELL2 | elongation factor, RNA polymerase II, 2 | -0.0564705 |
| HIF1A | hypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor) | -0.0550805 |
| NDRG1 | N-myc downstream regulated 1 | -0.0549485 |
| NEK7 | NIMA-related kinase 7 | -0.0537808 |
| FN1 | fibronectin 1 | -0.0530148 |
| RAB1A | RAB1A, member RAS oncogene family | -0.0500415 |
| CDC73 | cell division cycle 73 | -0.0486774 |
| CTNNB1 | catenin (cadherin-associated protein), beta 1, 88kDa | -0.0471961 |
| RICTOR | RPTOR independent companion of MTOR, complex 2 | -0.0471233 |
| MBNL1 | muscleblind-like splicing regulator 1 | -0.0462788 |
| WAC | WW domain containing adaptor with coiled-coil | -0.0460362 |
| S100A6 | S100 calcium binding protein A6 | -0.0453615 |
| RPS19 | ribosomal protein S19 | -0.0442632 |
| RHEB | Ras homolog enriched in brain | -0.0429781 |
| COPA | coatomer protein complex, subunit alpha | -0.0428171 |
| ZNF292 | zinc finger protein 292 | -0.0416446 |
| RAD21 | RAD21 homolog (S. pombe) | -0.0409917 |
| OGA | O-GlcNAcase | -0.0407789 |
| RNF145 | ring finger protein 145 | -0.0405688 |
| PTK2 | protein tyrosine kinase 2 | -0.0398865 |
| PCBP2 | poly(rC) binding protein 2 | -0.0396667 |
| SOD2 | superoxide dismutase 2, mitochondrial | -0.0395402 |
| CENPF | centromere protein F, 350/400kDa | -0.0394979 |
| YWHAZ | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta | -0.0391572 |
| CD44 | CD44 molecule (Indian blood group) | -0.0390686 |
| TXNRD1 | thioredoxin reductase 1 | -0.0380897 |
| PLOD2 | procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2 | -0.0380479 |
| TFG | TRK-fused gene | -0.0375762 |
| KMT2C | lysine (K)-specific methyltransferase 2C | -0.037389 |
| EPS8 | epidermal growth factor receptor pathway substrate 8 | -0.0373561 |
| UBC | ubiquitin C | -0.0372317 |
| GFPT1 | glutamine--fructose-6-phosphate transaminase 1 | -0.0364544 |
| JMJD1C | jumonji domain containing 1C | -0.0361645 |
| USP3 | ubiquitin specific peptidase 3 | -0.0361162 |
| UBR5 | ubiquitin protein ligase E3 component n-recognin 5 | -0.0360195 |
| CALU | calumenin | -0.0359559 |
| AHR | aryl hydrocarbon receptor | -0.035758 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.0348928 |
| UGCG | UDP-glucose ceramide glucosyltransferase | -0.0347945 |
| TM9SF3 | transmembrane 9 superfamily member 3 | -0.0343748 |
| KDM3A | lysine (K)-specific demethylase 3A | -0.0340746 |
| NUCKS1 | nuclear casein kinase and cyclin-dependent kinase substrate 1 | -0.0336538 |
| PELO | pelota homolog (Drosophila) | -0.0331849 |
| RPS6 | ribosomal protein S6 | -0.0330828 |
| RPS23 | ribosomal protein S23 | -0.0326791 |
| P4HB | prolyl 4-hydroxylase, beta polypeptide | -0.0326161 |
| ARL6IP1 | ADP-ribosylation factor-like 6 interacting protein 1 | -0.0326048 |
| UBE2D3 | ubiquitin-conjugating enzyme E2D 3 | -0.0324554 |
| PDIA6 | protein disulfide isomerase family A, member 6 | -0.0324398 |
| TENT2 | terminal nucleotidyltransferase 2 | -0.0318931 |
| ACBD3 | acyl-CoA binding domain containing 3 | -0.0311731 |
| PLEKHB2 | pleckstrin homology domain containing, family B (evectins) member 2 | -0.0306902 |
| SETD5 | SET domain containing 5 | -0.0305613 |
| RBM39 | RNA binding motif protein 39 | -0.030476 |
| FTH1 | ferritin, heavy polypeptide 1 | -0.0303345 |
| LIFR | leukemia inhibitory factor receptor alpha | -0.0300523 |
| ZFR | zinc finger RNA binding protein | -0.029903 |
| RPL28 | ribosomal protein L28 | -0.0299022 |
| CAPZA2 | capping protein (actin filament) muscle Z-line, alpha 2 | -0.0298769 |
| RHOA | ras homolog family member A | -0.0295299 |
| DNAJC1 | DnaJ (Hsp40) homolog, subfamily C, member 1 | -0.0295129 |
| PNISR | PNN-interacting serine/arginine-rich protein | -0.0295041 |
| PAFAH1B1 | platelet-activating factor acetylhydrolase 1b, regulatory subunit 1 (45kDa) | -0.0294794 |
| FNDC3B | fibronectin type III domain containing 3B | -0.0294517 |
| PHLDA1 | pleckstrin homology-like domain, family A, member 1 | -0.0293352 |
| FAM13A | family with sequence similarity 13, member A | -0.0293215 |
| TBL1XR1 | transducin (beta)-like 1 X-linked receptor 1 | -0.0293011 |
| MYH9 | myosin, heavy chain 9, non-muscle | -0.0291755 |
| UBE2H | ubiquitin-conjugating enzyme E2H | -0.0291693 |
| BTAF1 | BTAF1 RNA polymerase II, B-TFIID transcription factor-associated, 170kDa | -0.02907 |
| VEZT | vezatin, adherens junctions transmembrane protein | -0.0289319 |
| S100A10 | S100 calcium binding protein A10 | -0.0288581 |
| RPL23 | ribosomal protein L23 | -0.0287281 |
| NAP1L1 | nucleosome assembly protein 1-like 1 | -0.0287 |
| HELZ | helicase with zinc finger | -0.0286368 |
| ADAM9 | ADAM metallopeptidase domain 9 | -0.0281404 |
| GPRC5A | G protein-coupled receptor, class C, group 5, member A | -0.0281034 |
| HILPDA | hypoxia inducible lipid droplet-associated | -0.0279574 |
| RPS20 | ribosomal protein S20 | -0.0279212 |
| AP3B1 | adaptor-related protein complex 3, beta 1 subunit | -0.0279209 |
| MKLN1 | muskelin 1, intracellular mediator containing kelch motifs | -0.0277946 |
| RPS25 | ribosomal protein S25 | -0.0277714 |
| DHX9 | DEAH (Asp-Glu-Ala-His) box helicase 9 | -0.0274616 |
| STAT1 | signal transducer and activator of transcription 1, 91kDa | -0.02737 |
| RPS11 | ribosomal protein S11 | -0.0271935 |
| ARIH1 | ariadne RBR E3 ubiquitin protein ligase 1 | -0.0271768 |
| NPEPPS | aminopeptidase puromycin sensitive | -0.0271529 |
| TOP2A | topoisomerase (DNA) II alpha 170kDa | -0.0270555 |
| PELI1 | pellino E3 ubiquitin protein ligase 1 | -0.0270329 |
