| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | SBI-0640756 perturbation in hTERT-HPNE cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the SBI-0640756_hTERT-HPNE drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| STC1 | stanniocalcin 1 | 0.294503 |
| HLA-B | major histocompatibility complex, class I, B | 0.0971364 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | 0.0813692 |
| TNFAIP3 | tumor necrosis factor, alpha-induced protein 3 | 0.0804191 |
| FTL | ferritin, light polypeptide | 0.0685694 |
| RPS12 | ribosomal protein S12 | 0.0620656 |
| ITGB1 | integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) | 0.0617449 |
| PRRC2C | proline-rich coiled-coil 2C | 0.0566397 |
| DSCAM | Down syndrome cell adhesion molecule | 0.0541478 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.0521688 |
| COL8A1 | collagen, type VIII, alpha 1 | 0.0514808 |
| EIF1 | eukaryotic translation initiation factor 1 | 0.0501216 |
| TFPI | tissue factor pathway inhibitor (lipoprotein-associated coagulation inhibitor) | 0.0488993 |
| WSB1 | WD repeat and SOCS box containing 1 | 0.0485898 |
| B2M | beta-2-microglobulin | 0.0469385 |
| HLA-A | major histocompatibility complex, class I, A | 0.0403269 |
| AKAP12 | A kinase (PRKA) anchor protein 12 | 0.0400817 |
| ETS1 | v-ets avian erythroblastosis virus E26 oncogene homolog 1 | 0.0400738 |
| NFKBIA | nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha | 0.037411 |
| ITPR1 | inositol 1,4,5-trisphosphate receptor, type 1 | 0.037132 |
| ENO2 | enolase 2 (gamma, neuronal) | 0.0364646 |
| RPL4 | ribosomal protein L4 | 0.0349615 |
| ASPH | aspartate beta-hydroxylase | 0.0340191 |
| SRRM2 | serine/arginine repetitive matrix 2 | 0.0338587 |
| KDM3A | lysine (K)-specific demethylase 3A | 0.0335691 |
| RPS3 | ribosomal protein S3 | 0.0335345 |
| KMT2E | lysine (K)-specific methyltransferase 2E | 0.0329082 |
| TLN1 | talin 1 | 0.0325855 |
| COPA | coatomer protein complex, subunit alpha | 0.0319272 |
| TGFBI | transforming growth factor, beta-induced, 68kDa | 0.0318656 |
| RPS8 | ribosomal protein S8 | 0.0317598 |
| C1D | C1D nuclear receptor corepressor | 0.0314801 |
| MMP2 | matrix metallopeptidase 2 | 0.0313578 |
| HDLBP | high density lipoprotein binding protein | 0.0310612 |
| SPTBN1 | spectrin, beta, non-erythrocytic 1 | 0.0303126 |
| RAB13 | RAB13, member RAS oncogene family | 0.0297056 |
| ALCAM | activated leukocyte cell adhesion molecule | 0.0292915 |
| NR4A3 | nuclear receptor subfamily 4, group A, member 3 | 0.0286862 |
| RPL30 | ribosomal protein L30 | 0.0281957 |
| CALM2 | calmodulin 2 (phosphorylase kinase, delta) | 0.0279214 |
| ANGPTL4 | angiopoietin-like 4 | 0.0278674 |
| GOLGA4 | golgin A4 | 0.0277535 |
| COL4A1 | collagen, type IV, alpha 1 | 0.0276849 |
| CTNND1 | catenin (cadherin-associated protein), delta 1 | 0.0273404 |
| POMP | proteasome maturation protein | 0.0272501 |
| INTS6 | integrator complex subunit 6 | 0.0271034 |
| SCFD1 | sec1 family domain containing 1 | 0.0270315 |
| OPTN | optineurin | 0.0265014 |
| RBM25 | RNA binding motif protein 25 | 0.0263462 |
| PMAIP1 | phorbol-12-myristate-13-acetate-induced protein 1 | 0.0260115 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | 0.0253139 |
| SKP1 | S-phase kinase-associated protein 1 | 0.025206 |
| VCL | vinculin | 0.0251924 |
| TLE4 | transducin-like enhancer of split 4 | 0.0249828 |
| GYS1 | glycogen synthase 1 (muscle) | 0.0248873 |
| PPP1R15A | protein phosphatase 1, regulatory subunit 15A | 0.0243245 |
| KCNMA1 | potassium channel, calcium activated large conductance subfamily M alpha, member 1 | 0.0241102 |
| COL4A2 | collagen, type IV, alpha 2 | 0.0240504 |
| AKAP9 | A kinase (PRKA) anchor protein 9 | 0.0239397 |
| ATP2B1 | ATPase, Ca++ transporting, plasma membrane 1 | 0.0239355 |
| ANKRD11 | ankyrin repeat domain 11 | 0.0238355 |
| NAMPT | nicotinamide phosphoribosyltransferase | 0.0237844 |
| COG6 | component of oligomeric golgi complex 6 | 0.0234828 |
| SP100 | SP100 nuclear antigen | 0.0232557 |
| SON | SON DNA binding protein | 0.022995 |
| BRD2 | bromodomain containing 2 | 0.0229374 |
| GPHN | gephyrin | 0.0227126 |
| GPBP1 | GC-rich promoter binding protein 1 | 0.0226071 |
| ARRDC3 | arrestin domain containing 3 | 0.0223737 |
| SEC22A | SEC22 vesicle trafficking protein homolog A (S. cerevisiae) | 0.0223427 |
| IFI6 | interferon, alpha-inducible protein 6 | 0.0223034 |
| TMF1 | TATA element modulatory factor 1 | 0.02217 |
| SRSF11 | serine/arginine-rich splicing factor 11 | 0.0217874 |
| SF3B1 | splicing factor 3b, subunit 1, 155kDa | 0.0216384 |
| TPM1 | tropomyosin 1 (alpha) | 0.0213832 |
| GABBR1 | gamma-aminobutyric acid (GABA) B receptor, 1 | 0.0212928 |
| OGA | O-GlcNAcase | 0.0212428 |
| RPS27 | ribosomal protein S27 | 0.0210961 |
| RRBP1 | ribosome binding protein 1 | 0.0210841 |
| AMPD3 | adenosine monophosphate deaminase 3 | 0.0210664 |
| P4HA1 | prolyl 4-hydroxylase, alpha polypeptide I | 0.0209925 |
| GCC2 | GRIP and coiled-coil domain containing 2 | 0.0208251 |
| AHI1 | Abelson helper integration site 1 | 0.0208247 |
| RBM15 | RNA binding motif protein 15 | 0.0206487 |
| PLAUR | plasminogen activator, urokinase receptor | 0.0205679 |
| APLP2 | amyloid beta (A4) precursor-like protein 2 | 0.0205639 |
| CNKSR3 | CNKSR family member 3 | 0.0203622 |
| SET | SET nuclear proto-oncogene | 0.020254 |
| PALM2AKAP2 | PALM2 and AKAP2 fusion | 0.0198622 |
| SAMD8 | sterile alpha motif domain containing 8 | 0.0198601 |
| MBD5 | methyl-CpG binding domain protein 5 | 0.0198369 |
| ADM | adrenomedullin | 0.0197999 |
| PAPSS2 | 3'-phosphoadenosine 5'-phosphosulfate synthase 2 | 0.0197558 |
| EPAS1 | endothelial PAS domain protein 1 | 0.0197307 |
| FGFR1 | fibroblast growth factor receptor 1 | 0.0196966 |
| MINDY2 | MINDY lysine 48 deubiquitinase 2 | 0.0196501 |
| PLIN2 | perilipin 2 | 0.0194605 |
| MAGED1 | melanoma antigen family D1 | 0.0193016 |
| MARCHF6 | membrane associated ring-CH-type finger 6 | 0.0190715 |
| LOX | lysyl oxidase | 0.0189765 |
| Symbol | Name | Standardized Value |
|---|---|---|
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.252897 |
| COL1A1 | collagen, type I, alpha 1 | -0.158194 |
| SERPINE1 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1 | -0.124223 |
| FN1 | fibronectin 1 | -0.123377 |
| ADAMTS6 | ADAM metallopeptidase with thrombospondin type 1 motif, 6 | -0.106725 |
| MMP1 | matrix metallopeptidase 1 | -0.105443 |
| HMGA2 | high mobility group AT-hook 2 | -0.0991348 |
| COL6A3 | collagen, type VI, alpha 3 | -0.0879263 |
| LIMS1 | LIM and senescent cell antigen-like domains 1 | -0.081089 |
| PDE3A | phosphodiesterase 3A, cGMP-inhibited | -0.0810257 |
| PITPNC1 | phosphatidylinositol transfer protein, cytoplasmic 1 | -0.0809713 |
| COL6A1 | collagen, type VI, alpha 1 | -0.0806253 |
| ACTG1 | actin gamma 1 | -0.0792385 |
| NALF1 | NALCN channel auxiliary factor 1 | -0.0740697 |
| CD44 | CD44 molecule (Indian blood group) | -0.0736998 |
| AHNAK | AHNAK nucleoprotein | -0.0628606 |
| ADGRB3 | adhesion G protein-coupled receptor B3 | -0.0618725 |
| COL1A2 | collagen, type I, alpha 2 | -0.0616945 |
| PRKG1 | protein kinase, cGMP-dependent, type I | -0.0616488 |
| EGFR | epidermal growth factor receptor | -0.0602832 |
| FBN1 | fibrillin 1 | -0.0544481 |
| SGIP1 | SH3-domain GRB2-like (endophilin) interacting protein 1 | -0.0537688 |
| CDH13 | cadherin 13 | -0.0527396 |
| UACA | uveal autoantigen with coiled-coil domains and ankyrin repeats | -0.0522572 |
| OXR1 | oxidation resistance 1 | -0.0507223 |
| PHLDA1 | pleckstrin homology-like domain, family A, member 1 | -0.0500534 |
| MYO10 | myosin X | -0.0499757 |
| CXCL8 | chemokine (C-X-C motif) ligand 8 | -0.0492283 |
| EMP1 | epithelial membrane protein 1 | -0.0491168 |
| CEMIP | cell migration inducing protein, hyaluronan binding | -0.0486867 |
| POTEF | POTE ankyrin domain family, member F | -0.0486767 |
| PDE8A | phosphodiesterase 8A | -0.0480561 |
| TIMP2 | TIMP metallopeptidase inhibitor 2 | -0.0457414 |
| LOXL2 | lysyl oxidase-like 2 | -0.0455432 |
| CCND1 | cyclin D1 | -0.0437027 |
| MCL1 | myeloid cell leukemia 1 | -0.0419243 |
| ATP13A3 | ATPase type 13A3 | -0.0418693 |
| ATP1B3 | ATPase, Na+/K+ transporting, beta 3 polypeptide | -0.0410088 |
| MICAL2 | microtubule associated monooxygenase, calponin and LIM domain containing 2 | -0.0403966 |
| ADAMTS12 | ADAM metallopeptidase with thrombospondin type 1 motif, 12 | -0.0383539 |
| FRMD4A | FERM domain containing 4A | -0.0375714 |
| MAP4K4 | mitogen-activated protein kinase kinase kinase kinase 4 | -0.0373479 |
| IMMP2L | IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) | -0.0364272 |
| PTK2 | protein tyrosine kinase 2 | -0.0361723 |
| LRRFIP1 | leucine rich repeat (in FLII) interacting protein 1 | -0.0355065 |
| PDE4D | phosphodiesterase 4D, cAMP-specific | -0.0355019 |
| PDIA3 | protein disulfide isomerase family A, member 3 | -0.0349563 |
| ABCA1 | ATP-binding cassette, sub-family A (ABC1), member 1 | -0.0345781 |
| GLIS3 | GLIS family zinc finger 3 | -0.034543 |
| RPS16 | ribosomal protein S16 | -0.0341851 |
| AFF3 | AF4/FMR2 family, member 3 | -0.0338968 |
| ARHGAP22 | Rho GTPase activating protein 22 | -0.0338615 |
| RPS23 | ribosomal protein S23 | -0.0336658 |
| LAMC1 | laminin, gamma 1 (formerly LAMB2) | -0.0336612 |
| WAC | WW domain containing adaptor with coiled-coil | -0.0336565 |
| NAV1 | neuron navigator 1 | -0.0334691 |
| EXT1 | exostosin glycosyltransferase 1 | -0.0334375 |
| CD59 | CD59 molecule, complement regulatory protein | -0.0327608 |
| SIPA1L3 | signal-induced proliferation-associated 1 like 3 | -0.0327093 |
| SASH1 | SAM and SH3 domain containing 1 | -0.0324086 |
| SLC8A1 | solute carrier family 8 (sodium/calcium exchanger), member 1 | -0.0318612 |
| SAMD4A | sterile alpha motif domain containing 4A | -0.0314424 |
| NPTX1 | neuronal pentraxin I | -0.0314083 |
| JARID2 | jumonji, AT rich interactive domain 2 | -0.0311677 |
| DCBLD2 | discoidin, CUB and LCCL domain containing 2 | -0.0310162 |
| SEC31A | SEC31 homolog A (S. cerevisiae) | -0.0308447 |
| GNB1 | guanine nucleotide binding protein (G protein), beta polypeptide 1 | -0.0301663 |
| WNT5A | wingless-type MMTV integration site family, member 5A | -0.0298863 |
| TPM4 | tropomyosin 4 | -0.0297582 |
| RPS24 | ribosomal protein S24 | -0.0293798 |
| RPL35A | ribosomal protein L35a | -0.0289219 |
| P4HB | prolyl 4-hydroxylase, beta polypeptide | -0.0288191 |
| PRSS23 | protease, serine, 23 | -0.028697 |
| PLOD2 | procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2 | -0.0286887 |
| PPIB | peptidylprolyl isomerase B (cyclophilin B) | -0.0285171 |
| ERRFI1 | ERBB receptor feedback inhibitor 1 | -0.0285007 |
| LGALS1 | lectin, galactoside-binding, soluble, 1 | -0.0284975 |
| MKLN1 | muskelin 1, intracellular mediator containing kelch motifs | -0.0278795 |
| DOCK1 | dedicator of cytokinesis 1 | -0.0276155 |
| RABGEF1 | RAB guanine nucleotide exchange factor (GEF) 1 | -0.0274527 |
| SNX9 | sorting nexin 9 | -0.0273453 |
| ADAMTS16 | ADAM metallopeptidase with thrombospondin type 1 motif, 16 | -0.0273144 |
| PRKAR1A | protein kinase, cAMP-dependent, regulatory, type I, alpha | -0.0268946 |
| TMEM158 | transmembrane protein 158 (gene/pseudogene) | -0.026789 |
| DIAPH2 | diaphanous-related formin 2 | -0.0267754 |
| ZFAND3 | zinc finger, AN1-type domain 3 | -0.0267394 |
| RPS29 | ribosomal protein S29 | -0.02656 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.0265595 |
| SMURF2 | SMAD specific E3 ubiquitin protein ligase 2 | -0.0264889 |
| TEAD1 | TEA domain family member 1 (SV40 transcriptional enhancer factor) | -0.0264756 |
| NCKAP5 | NCK-associated protein 5 | -0.0261724 |
| S100A6 | S100 calcium binding protein A6 | -0.0259877 |
| AGAP1 | ArfGAP with GTPase domain, ankyrin repeat and PH domain 1 | -0.0258262 |
| CLMP | CXADR-like membrane protein | -0.0257679 |
| PTPRK | protein tyrosine phosphatase, receptor type, K | -0.0255196 |
| SLIT2 | slit homolog 2 (Drosophila) | -0.0254894 |
| MAP4 | microtubule-associated protein 4 | -0.025447 |
| ARIH1 | ariadne RBR E3 ubiquitin protein ligase 1 | -0.0253149 |
| RPLP2 | ribosomal protein, large, P2 | -0.0249931 |
| MBNL1 | muscleblind-like splicing regulator 1 | -0.0249465 |
