SC-1 Gene Set

Dataset COSMIC Cell Line Gene Mutation Profiles
Category genomics
Type cell line
Description A immortal mouse embryo-derived cell line cell that has the characteristics: Embryonal cell line derived from wild mouse. Sensitive to leukemia viruses. (Cell Line Ontology, CLO_0050606)
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Genes

262 genes mutated in the SC-1 cell line from the COSMIC Cell Line Gene Mutation Profiles dataset.

Symbol Name
ABCA6 ATP-binding cassette, sub-family A (ABC1), member 6
ABCG4 ATP-binding cassette, sub-family G (WHITE), member 4
ADAMTS13 ADAM metallopeptidase with thrombospondin type 1 motif, 13
ADAMTS17 ADAM metallopeptidase with thrombospondin type 1 motif, 17
ADAMTS18 ADAM metallopeptidase with thrombospondin type 1 motif, 18
ADAMTSL2 ADAMTS-like 2
ADGRL2 adhesion G protein-coupled receptor L2
ADGRL3 adhesion G protein-coupled receptor L3
AGER advanced glycosylation end product-specific receptor
AKR7A2 aldo-keto reductase family 7, member A2 (aflatoxin aldehyde reductase)
ALKBH5 AlkB family member 5, RNA demethylase
ALS2CR11 amyotrophic lateral sclerosis 2 (juvenile) chromosome region, candidate 11
ANK2 ankyrin 2, neuronal
ANKRD35 ankyrin repeat domain 35
ANKRD36C ankyrin repeat domain 36C
AQP7 aquaporin 7
ARHGAP42 Rho GTPase activating protein 42
ASB18 ankyrin repeat and SOCS box containing 18
ASB3 ankyrin repeat and SOCS box containing 3
ASH1L ash1 (absent, small, or homeotic)-like (Drosophila)
ATP13A3 ATPase type 13A3
ATP6V1B2 ATPase, H+ transporting, lysosomal 56/58kDa, V1 subunit B2
BCL2 B-cell CLL/lymphoma 2
BIRC2 baculoviral IAP repeat containing 2
BUD13 BUD13 homolog (S. cerevisiae)
CACNA1H calcium channel, voltage-dependent, T type, alpha 1H subunit
CACNA1S calcium channel, voltage-dependent, L type, alpha 1S subunit
CALR3 calreticulin 3
CAPN1 calpain 1, (mu/I) large subunit
CAPSL calcyphosine-like
CC2D1A coiled-coil and C2 domain containing 1A
CCND3 cyclin D3
CELSR1 cadherin, EGF LAG seven-pass G-type receptor 1
CES3 carboxylesterase 3
CHD7 chromodomain helicase DNA binding protein 7
CHD8 chromodomain helicase DNA binding protein 8
CHRNG cholinergic receptor, nicotinic, gamma (muscle)
CKAP5 cytoskeleton associated protein 5
CKM creatine kinase, muscle
CLIP2 CAP-GLY domain containing linker protein 2
CNR2 cannabinoid receptor 2 (macrophage)
COL19A1 collagen, type XIX, alpha 1
COPZ2 coatomer protein complex, subunit zeta 2
CPEB2 cytoplasmic polyadenylation element binding protein 2
CPT1B carnitine palmitoyltransferase 1B (muscle)
CREBBP CREB binding protein
CREBL2 cAMP responsive element binding protein-like 2
CRYZ crystallin, zeta (quinone reductase)
CSRP3 cysteine and glycine-rich protein 3 (cardiac LIM protein)
CTNNA3 catenin (cadherin-associated protein), alpha 3
CTSG cathepsin G
DCUN1D4 DCN1, defective in cullin neddylation 1, domain containing 4
DDX60L DEAD (Asp-Glu-Ala-Asp) box polypeptide 60-like
DEK DEK proto-oncogene
DGKI diacylglycerol kinase, iota
DISP1 dispatched homolog 1 (Drosophila)
DMBT1 deleted in malignant brain tumors 1
DPP9 dipeptidyl-peptidase 9
DTHD1 death domain containing 1
DUSP13 dual specificity phosphatase 13
DUSP27 dual specificity phosphatase 27 (putative)
DYX1C1 dyslexia susceptibility 1 candidate 1
EEF1DP1 eukaryotic translation elongation factor 1 delta pseudogene 1
ENKUR enkurin, TRPC channel interacting protein
ENPP3 ectonucleotide pyrophosphatase/phosphodiesterase 3
EPB41L4A erythrocyte membrane protein band 4.1 like 4A
EPC1 enhancer of polycomb homolog 1 (Drosophila)
EPPK1 epiplakin 1
EPYC epiphycan
F12 coagulation factor XII (Hageman factor)
FABP12 fatty acid binding protein 12
FAM179A family with sequence similarity 179, member A
FAM193A family with sequence similarity 193, member A
FGF6 fibroblast growth factor 6
FLOT2 flotillin 2
FMN2 formin 2
FPR3 formyl peptide receptor 3
GPATCH2 G patch domain containing 2
GRAMD1C GRAM domain containing 1C
GRID2 glutamate receptor, ionotropic, delta 2
GRIK1 glutamate receptor, ionotropic, kainate 1
GSTCD glutathione S-transferase, C-terminal domain containing
GTF2F1 general transcription factor IIF, polypeptide 1, 74kDa
HGSNAT heparan-alpha-glucosaminide N-acetyltransferase
HIST1H2AL histone cluster 1, H2al
HIST1H2BK histone cluster 1, H2bk
HLA-B major histocompatibility complex, class I, B
HLTF helicase-like transcription factor
HMGCR 3-hydroxy-3-methylglutaryl-CoA reductase
HSPB2 heat shock 27kDa protein 2
HTR2C 5-hydroxytryptamine (serotonin) receptor 2C, G protein-coupled
HYDIN HYDIN, axonemal central pair apparatus protein
IARS2 isoleucyl-tRNA synthetase 2, mitochondrial
IBSP integrin-binding sialoprotein
IFT172 intraflagellar transport 172
IFT88 intraflagellar transport 88
IGF1R insulin-like growth factor 1 receptor
IL1RAP interleukin 1 receptor accessory protein
IL1RAPL2 interleukin 1 receptor accessory protein-like 2
IL34 interleukin 34
INF2 inverted formin, FH2 and WH2 domain containing
INTS1 integrator complex subunit 1
IQCA1 IQ motif containing with AAA domain 1
IQUB IQ motif and ubiquitin domain containing
ITGAX integrin, alpha X (complement component 3 receptor 4 subunit)
ITSN1 intersectin 1 (SH3 domain protein)
JAKMIP1 janus kinase and microtubule interacting protein 1
KAZN kazrin, periplakin interacting protein
KCNH8 potassium channel, voltage gated eag related subfamily H, member 8
KIAA0556 KIAA0556
KIAA1467 KIAA1467
KIAA1671 KIAA1671
KIF26B kinesin family member 26B
KLC4 kinesin light chain 4
KMT2D lysine (K)-specific methyltransferase 2D
KRT72 keratin 72, type II
LIG1 ligase I, DNA, ATP-dependent
LOC390956 peptidyl-prolyl cis-trans isomerase A pseudogene
LRCH3 leucine-rich repeats and calponin homology (CH) domain containing 3
LRP5 low density lipoprotein receptor-related protein 5
LRRIQ1 leucine-rich repeats and IQ motif containing 1
MAGI3 membrane associated guanylate kinase, WW and PDZ domain containing 3
MAPK4 mitogen-activated protein kinase 4
MBTPS1 membrane-bound transcription factor peptidase, site 1
MET MET proto-oncogene, receptor tyrosine kinase
MIA3 melanoma inhibitory activity family, member 3
MICAL2 microtubule associated monooxygenase, calponin and LIM domain containing 2
MMP14 matrix metallopeptidase 14 (membrane-inserted)
MPDZ multiple PDZ domain protein
MPPED2 metallophosphoesterase domain containing 2
MROH7 maestro heat-like repeat family member 7
MTDH metadherin
MUC17 mucin 17, cell surface associated
MUC4 mucin 4, cell surface associated
MUC5AC mucin 5AC, oligomeric mucus/gel-forming
MUC5B mucin 5B, oligomeric mucus/gel-forming
MVD mevalonate (diphospho) decarboxylase
MYC v-myc avian myelocytomatosis viral oncogene homolog
MYH2 myosin, heavy chain 2, skeletal muscle, adult
MYO18A myosin XVIIIA
MYO1E myosin IE
NCF4 neutrophil cytosolic factor 4, 40kDa
NEB nebulin
NEDD8 neural precursor cell expressed, developmentally down-regulated 8
NPPB natriuretic peptide B
NR2E3 nuclear receptor subfamily 2, group E, member 3
NT5C3A 5'-nucleotidase, cytosolic IIIA
NUDT7 nudix (nucleoside diphosphate linked moiety X)-type motif 7
NUP210 nucleoporin 210kDa
NYAP2 neuronal tyrosine-phosphorylated phosphoinositide-3-kinase adaptor 2
OR4K14 olfactory receptor, family 4, subfamily K, member 14
OSBP2 oxysterol binding protein 2
OTOG otogelin
P4HA2 prolyl 4-hydroxylase, alpha polypeptide II
PAIP1 poly(A) binding protein interacting protein 1
PAQR8 progestin and adipoQ receptor family member VIII
PCDH15 protocadherin-related 15
PCDH7 protocadherin 7
PCDHB1 protocadherin beta 1
PCDHB10 protocadherin beta 10
PCDHB14 protocadherin beta 14
PCDHB18P protocadherin beta 18 pseudogene
PCDHGC5 protocadherin gamma subfamily C, 5
PCGF1 polycomb group ring finger 1
PCNT pericentrin
PDE4DIP phosphodiesterase 4D interacting protein
PECR peroxisomal trans-2-enoyl-CoA reductase
PHF13 PHD finger protein 13
PHF7 PHD finger protein 7
PITX2 paired-like homeodomain 2
PLEC plectin
PLSCR5 phospholipid scramblase family, member 5
PLVAP plasmalemma vesicle associated protein
POU2AF1 POU class 2 associating factor 1
PPM1H protein phosphatase, Mg2+/Mn2+ dependent, 1H
PPP1R12B protein phosphatase 1, regulatory subunit 12B
PPP2R2A protein phosphatase 2, regulatory subunit B, alpha
PPWD1 peptidylprolyl isomerase domain and WD repeat containing 1
PRDM12 PR domain containing 12
PRICKLE1 prickle homolog 1 (Drosophila)
PRRC2A proline-rich coiled-coil 2A
PSG1 pregnancy specific beta-1-glycoprotein 1
PWWP2B PWWP domain containing 2B
RAB11FIP1 RAB11 family interacting protein 1 (class I)
RBM11 RNA binding motif protein 11
RBM46 RNA binding motif protein 46
RC3H1 ring finger and CCCH-type domains 1
REST RE1-silencing transcription factor
RGS4 regulator of G-protein signaling 4
RICTOR RPTOR independent companion of MTOR, complex 2
RNASEL ribonuclease L (2',5'-oligoisoadenylate synthetase-dependent)
RNPEP arginyl aminopeptidase (aminopeptidase B)
ROBO3 roundabout, axon guidance receptor, homolog 3 (Drosophila)
RP1 retinitis pigmentosa 1 (autosomal dominant)
RPF1 ribosome production factor 1 homolog (S. cerevisiae)
RRP12 ribosomal RNA processing 12 homolog (S. cerevisiae)
RSPO1 R-spondin 1
RTL1 retrotransposon-like 1
RTN2 reticulon 2
SAXO2 stabilizer of axonemal microtubules 2
SDK1 sidekick cell adhesion molecule 1
SEC24C SEC24 family member C
SENP1 SUMO1/sentrin specific peptidase 1
SERPINA10 serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 10
SERPINB13 serpin peptidase inhibitor, clade B (ovalbumin), member 13
SH2D4A SH2 domain containing 4A
SIGLEC6 sialic acid binding Ig-like lectin 6
SIMC1 SUMO-interacting motifs containing 1
SLC12A7 solute carrier family 12 (potassium/chloride transporter), member 7
SLC22A15 solute carrier family 22, member 15
SLC5A5 solute carrier family 5 (sodium/iodide cotransporter), member 5
SLC6A13 solute carrier family 6 (neurotransmitter transporter), member 13
SLX4 SLX4 structure-specific endonuclease subunit
SMC2 structural maintenance of chromosomes 2
SORL1 sortilin-related receptor, L(DLR class) A repeats containing
SPATA17 spermatogenesis associated 17
SPTBN4 spectrin, beta, non-erythrocytic 4
SRSF12 serine/arginine-rich splicing factor 12
ST8SIA5 ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransferase 5
SYNE1 spectrin repeat containing, nuclear envelope 1
SYT3 synaptotagmin III
TAF8 TAF8 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 43kDa
TCF3 transcription factor 3
TDG thymine-DNA glycosylase
TENM2 teneurin transmembrane protein 2
TENM4 teneurin transmembrane protein 4
TET3 tet methylcytosine dioxygenase 3
TFR2 transferrin receptor 2
TG thyroglobulin
TGM4 transglutaminase 4
TLR2 toll-like receptor 2
TMEM63C transmembrane protein 63C
TMEM8A transmembrane protein 8A
TMTC4 transmembrane and tetratricopeptide repeat containing 4
TNFSF8 tumor necrosis factor (ligand) superfamily, member 8
TP53 tumor protein p53
TRIM46 tripartite motif containing 46
TRIM49C tripartite motif containing 49C
TRIP6 thyroid hormone receptor interactor 6
TRPV5 transient receptor potential cation channel, subfamily V, member 5
TSGA10 testis specific, 10
TSNARE1 t-SNARE domain containing 1
TTC24 tetratricopeptide repeat domain 24
TTN titin
TUBB tubulin, beta class I
URB1 URB1 ribosome biogenesis 1 homolog (S. cerevisiae)
USP14 ubiquitin specific peptidase 14 (tRNA-guanine transglycosylase)
USP43 ubiquitin specific peptidase 43
VAV1 vav 1 guanine nucleotide exchange factor
VRTN vertebrae development associated
VTA1 vesicle (multivesicular body) trafficking 1
WASH4P WAS protein family homolog 4 pseudogene
WDR49 WD repeat domain 49
WDR70 WD repeat domain 70
WWP1 WW domain containing E3 ubiquitin protein ligase 1
ZHX3 zinc fingers and homeoboxes 3
ZMAT1 zinc finger, matrin-type 1
ZNF236 zinc finger protein 236
ZNF385C zinc finger protein 385C
ZNF696 zinc finger protein 696
ZNF862 zinc finger protein 862
ZSCAN23 zinc finger and SCAN domain containing 23