SC-19220-7090 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
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Genes

198 genes differentially expressed following the SC-19220-7090 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
AAMDC adipogenesis associated, Mth938 domain containing
ABCD1 ATP-binding cassette, sub-family D (ALD), member 1
ADPRM ADP-ribose/CDP-alcohol diphosphatase, manganese-dependent
ALDH1B1 aldehyde dehydrogenase 1 family, member B1
ANKRD12 ankyrin repeat domain 12
AP2A2 adaptor-related protein complex 2, alpha 2 subunit
AP3B1 adaptor-related protein complex 3, beta 1 subunit
ARNT aryl hydrocarbon receptor nuclear translocator
ATP9A ATPase, class II, type 9A
ATXN2L ataxin 2-like
BHLHE41 basic helix-loop-helix family, member e41
BMP2K BMP2 inducible kinase
BUB1 BUB1 mitotic checkpoint serine/threonine kinase
C5ORF45 chromosome 5 open reading frame 45
CA11 carbonic anhydrase XI
CA12 carbonic anhydrase XII
CACNB2 calcium channel, voltage-dependent, beta 2 subunit
CCDC93 coiled-coil domain containing 93
CDK2 cyclin-dependent kinase 2
CDK3 cyclin-dependent kinase 3
CEP290 centrosomal protein 290kDa
CHST10 carbohydrate sulfotransferase 10
CSTA cystatin A (stefin A)
CXCR4 chemokine (C-X-C motif) receptor 4
DAPP1 dual adaptor of phosphotyrosine and 3-phosphoinositides
DDX17 DEAD (Asp-Glu-Ala-Asp) box helicase 17
DOCK6 dedicator of cytokinesis 6
DUSP7 dual specificity phosphatase 7
DYSF dysferlin
ENGASE endo-beta-N-acetylglucosaminidase
FAXDC2 fatty acid hydroxylase domain containing 2
GALC galactosylceramidase
GATA4 GATA binding protein 4
GPC4 glypican 4
GPR107 G protein-coupled receptor 107
HPS1 Hermansky-Pudlak syndrome 1
HSPG2 heparan sulfate proteoglycan 2
IGHG1 immunoglobulin heavy constant gamma 1 (G1m marker)
ITGA6 integrin, alpha 6
KDM4C lysine (K)-specific demethylase 4C
LIG3 ligase III, DNA, ATP-dependent
LMF2 lipase maturation factor 2
LONP2 lon peptidase 2, peroxisomal
LTB4R leukotriene B4 receptor
MAP3K9 mitogen-activated protein kinase kinase kinase 9
MARK2 MAP/microtubule affinity-regulating kinase 2
MR1 major histocompatibility complex, class I-related
MSI1 musashi RNA-binding protein 1
MST1L macrophage stimulating 1-like
MT1G metallothionein 1G
MTUS1 microtubule associated tumor suppressor 1
MYL6 myosin, light chain 6, alkali, smooth muscle and non-muscle
MZF1 myeloid zinc finger 1
NXT2 nuclear transport factor 2-like export factor 2
OR7E47P olfactory receptor, family 7, subfamily E, member 47 pseudogene
PALM paralemmin
PARD3 par-3 family cell polarity regulator
PARPBP PARP1 binding protein
PCDHB8 protocadherin beta 8
PICALM phosphatidylinositol binding clathrin assembly protein
PIGO phosphatidylinositol glycan anchor biosynthesis, class O
PITPNM1 phosphatidylinositol transfer protein, membrane-associated 1
PLD2 phospholipase D2
POFUT1 protein O-fucosyltransferase 1
POGZ pogo transposable element with ZNF domain
POLR3G polymerase (RNA) III (DNA directed) polypeptide G (32kD)
PPP2R5B protein phosphatase 2, regulatory subunit B', beta
PRPH peripherin
PTPN12 protein tyrosine phosphatase, non-receptor type 12
RAB5A RAB5A, member RAS oncogene family
RBM8A RNA binding motif protein 8A
REPS1 RALBP1 associated Eps domain containing 1
RPS28 ribosomal protein S28
SETD1B SET domain containing 1B
SF3A2 splicing factor 3a, subunit 2, 66kDa
SFI1 Sfi1 homolog, spindle assembly associated (yeast)
SLC39A9 solute carrier family 39, member 9
SMIM8 small integral membrane protein 8
SMURF1 SMAD specific E3 ubiquitin protein ligase 1
SORBS3 sorbin and SH3 domain containing 3
SS18 synovial sarcoma translocation, chromosome 18
STX3 syntaxin 3
STX7 syntaxin 7
SUGP2 SURP and G patch domain containing 2
TDRD3 tudor domain containing 3
TMEM63A transmembrane protein 63A
TRIM23 tripartite motif containing 23
TTC28 tetratricopeptide repeat domain 28
TUBA3C tubulin, alpha 3c
UBXN1 UBX domain protein 1
USP34 ubiquitin specific peptidase 34
WDR1 WD repeat domain 1
ZFAND6 zinc finger, AN1-type domain 6
ZHX3 zinc fingers and homeoboxes 3
ZNF16 zinc finger protein 16
ZNF350 zinc finger protein 350
ZNF767P zinc finger family member 767, pseudogene
ZNF816 zinc finger protein 816
ZSCAN26 zinc finger and SCAN domain containing 26

decreased expression

Symbol Name
ACVR2B activin A receptor, type IIB
APOLD1 apolipoprotein L domain containing 1
ARHGEF3 Rho guanine nucleotide exchange factor (GEF) 3
B3GNT4 UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 4
BBC3 BCL2 binding component 3
BCAS1 breast carcinoma amplified sequence 1
BGLAP bone gamma-carboxyglutamate (gla) protein
BIK BCL2-interacting killer (apoptosis-inducing)
BTF3P11 basic transcription factor 3 pseudogene 11
C17ORF53 chromosome 17 open reading frame 53
C21ORF91 chromosome 21 open reading frame 91
CCDC57 coiled-coil domain containing 57
CCDC68 coiled-coil domain containing 68
CNPY3 canopy FGF signaling regulator 3
CORO1A coronin, actin binding protein, 1A
CRELD1 cysteine-rich with EGF-like domains 1
DNAAF2 dynein, axonemal, assembly factor 2
DSE dermatan sulfate epimerase
DUSP13 dual specificity phosphatase 13
ECHDC3 enoyl CoA hydratase domain containing 3
FAAH fatty acid amide hydrolase
FAM155B family with sequence similarity 155, member B
FAM189A2 family with sequence similarity 189, member A2
FANCC Fanconi anemia, complementation group C
GABPA GA binding protein transcription factor, alpha subunit 60kDa
GPBP1L1 GC-rich promoter binding protein 1-like 1
GPR19 G protein-coupled receptor 19
GRTP1 growth hormone regulated TBC protein 1
HIST1H2AG histone cluster 1, H2ag
HIST1H2AI histone cluster 1, H2ai
IL15RA interleukin 15 receptor, alpha
IRAK4 interleukin-1 receptor-associated kinase 4
IRF6 interferon regulatory factor 6
JMJD4 jumonji domain containing 4
KIAA0894 KIAA0894 protein
LHPP phospholysine phosphohistidine inorganic pyrophosphate phosphatase
LIN7B lin-7 homolog B (C. elegans)
LOC390998 ribosomal protein L10 pseudogene
LRRC42 leucine rich repeat containing 42
MAFB v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog B
MUL1 mitochondrial E3 ubiquitin protein ligase 1
NARFL nuclear prelamin A recognition factor-like
NCAM2 neural cell adhesion molecule 2
NEK11 NIMA-related kinase 11
NUDT18 nudix (nucleoside diphosphate linked moiety X)-type motif 18
NUP62CL nucleoporin 62kDa C-terminal like
PARD6A par-6 family cell polarity regulator alpha
PCSK7 proprotein convertase subtilisin/kexin type 7
PDLIM2 PDZ and LIM domain 2 (mystique)
PEX26 peroxisomal biogenesis factor 26
PIGL phosphatidylinositol glycan anchor biosynthesis, class L
PIK3R2 phosphoinositide-3-kinase, regulatory subunit 2 (beta)
PLD3 phospholipase D family, member 3
PLEKHM2 pleckstrin homology domain containing, family M (with RUN domain) member 2
POLL polymerase (DNA directed), lambda
PPP1R3C protein phosphatase 1, regulatory subunit 3C
PRR3 proline rich 3
RAB11FIP5 RAB11 family interacting protein 5 (class I)
RAB3A RAB3A, member RAS oncogene family
RARS arginyl-tRNA synthetase
RRP9 ribosomal RNA processing 9, small subunit (SSU) processome component, homolog (yeast)
SETD1A SET domain containing 1A
SLC12A8 solute carrier family 12, member 8
SLC35C1 solute carrier family 35 (GDP-fucose transporter), member C1
SLC39A7 solute carrier family 39 (zinc transporter), member 7
SMG1 SMG1 phosphatidylinositol 3-kinase-related kinase
SND1-IT1 SND1 intronic transcript 1
SOX12 SRY (sex determining region Y)-box 12
SOX3 SRY (sex determining region Y)-box 3
SPHK1 sphingosine kinase 1
SPINK5 serine peptidase inhibitor, Kazal type 5
SRPX sushi-repeat containing protein, X-linked
SUN2 Sad1 and UNC84 domain containing 2
SYCP2 synaptonemal complex protein 2
TAF4B TAF4b RNA polymerase II, TATA box binding protein (TBP)-associated factor, 105kDa
TAP1 transporter 1, ATP-binding cassette, sub-family B (MDR/TAP)
TBC1D17 TBC1 domain family, member 17
TEX40 testis expressed 40
TMEM115 transmembrane protein 115
TMSB15A thymosin beta 15a
TP53BP2 tumor protein p53 binding protein 2
TSC22D4 TSC22 domain family, member 4
TTC4 tetratricopeptide repeat domain 4
TTLL1 tubulin tyrosine ligase-like family member 1
TUBG2 tubulin, gamma 2
UBXN6 UBX domain protein 6
UNC119 unc-119 homolog (C. elegans)
URM1 ubiquitin related modifier 1
USB1 U6 snRNA biogenesis 1
USP5 ubiquitin specific peptidase 5 (isopeptidase T)
VPS33A vacuolar protein sorting 33 homolog A (S. cerevisiae)
VSIG10 V-set and immunoglobulin domain containing 10
WNT16 wingless-type MMTV integration site family, member 16
YEATS2 YEATS domain containing 2
ZAK sterile alpha motif and leucine zipper containing kinase AZK
ZBTB39 zinc finger and BTB domain containing 39
ZBTB48 zinc finger and BTB domain containing 48
ZNF204P zinc finger protein 204, pseudogene
ZNF276 zinc finger protein 276