SC-560-6870 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
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Genes

199 genes differentially expressed following the SC-560-6870 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
AFAP1 actin filament associated protein 1
AGBL2 ATP/GTP binding protein-like 2
AHI1 Abelson helper integration site 1
AQP3 aquaporin 3 (Gill blood group)
ARL15 ADP-ribosylation factor-like 15
ATHL1 ATH1, acid trehalase-like 1 (yeast)
ATP6V0A2 ATPase, H+ transporting, lysosomal V0 subunit a2
AURKA aurora kinase A
BAZ1B bromodomain adjacent to zinc finger domain, 1B
BBS9 Bardet-Biedl syndrome 9
BIRC7 baculoviral IAP repeat containing 7
BMP1 bone morphogenetic protein 1
BMP5 bone morphogenetic protein 5
BTN2A1 butyrophilin, subfamily 2, member A1
CCDC121 coiled-coil domain containing 121
CHAC1 ChaC glutathione-specific gamma-glutamylcyclotransferase 1
CHRNA6 cholinergic receptor, nicotinic, alpha 6 (neuronal)
CRY2 cryptochrome circadian clock 2
CXCR4 chemokine (C-X-C motif) receptor 4
DGKE diacylglycerol kinase, epsilon 64kDa
EDAR ectodysplasin A receptor
EGLN3 egl-9 family hypoxia-inducible factor 3
ESR1 estrogen receptor 1
FAM212B family with sequence similarity 212, member B
FGD1 FYVE, RhoGEF and PH domain containing 1
FGF4 fibroblast growth factor 4
FLI1 Fli-1 proto-oncogene, ETS transcription factor
GAS7 growth arrest-specific 7
GHRHR growth hormone releasing hormone receptor
GLB1L galactosidase, beta 1-like
GLUD2 glutamate dehydrogenase 2
GOLGA8A golgin A8 family, member A
GPD2 glycerol-3-phosphate dehydrogenase 2 (mitochondrial)
GRINA glutamate receptor, ionotropic, N-methyl D-aspartate-associated protein 1 (glutamate binding)
GSTA3 glutathione S-transferase alpha 3
HDAC7 histone deacetylase 7
HLA-DMA major histocompatibility complex, class II, DM alpha
HSPB3 heat shock 27kDa protein 3
IFT74 intraflagellar transport 74
ITM2C integral membrane protein 2C
LIN7B lin-7 homolog B (C. elegans)
LINC00341 long intergenic non-protein coding RNA 341
LYPD1 LY6/PLAUR domain containing 1
LZTS3 leucine zipper, putative tumor suppressor family member 3
MAP3K1 mitogen-activated protein kinase kinase kinase 1, E3 ubiquitin protein ligase
MPDZ multiple PDZ domain protein
MST1R macrophage stimulating 1 receptor
MTM1 myotubularin 1
MXD4 MAX dimerization protein 4
NBL1 neuroblastoma 1, DAN family BMP antagonist
NEK11 NIMA-related kinase 11
NKX3-2 NK3 homeobox 2
NLRX1 NLR family member X1
NOL10 nucleolar protein 10
NPR3 natriuretic peptide receptor 3
ORAI2 ORAI calcium release-activated calcium modulator 2
PALM paralemmin
PDK2 pyruvate dehydrogenase kinase, isozyme 2
PHLPP1 PH domain and leucine rich repeat protein phosphatase 1
PILRA paired immunoglobin-like type 2 receptor alpha
PLK4 polo-like kinase 4
PLXNA3 plexin A3
PODXL podocalyxin-like
POMT2 protein-O-mannosyltransferase 2
PPP5C protein phosphatase 5, catalytic subunit
PRDM2 PR domain containing 2, with ZNF domain
PRICKLE3 prickle homolog 3 (Drosophila)
QKI QKI, KH domain containing, RNA binding
RAB6B RAB6B, member RAS oncogene family
RANBP3 RAN binding protein 3
RPAP1 RNA polymerase II associated protein 1
RPL23AP32 ribosomal protein L23a pseudogene 32
RPL7 ribosomal protein L7
RTN2 reticulon 2
S100A2 S100 calcium binding protein A2
SECTM1 secreted and transmembrane 1
SH3BP2 SH3-domain binding protein 2
SIX1 SIX homeobox 1
SLC1A4 solute carrier family 1 (glutamate/neutral amino acid transporter), member 4
SLC22A14 solute carrier family 22, member 14
SLC2A11 solute carrier family 2 (facilitated glucose transporter), member 11
SRI sorcin
TCTN2 tectonic family member 2
TFPI tissue factor pathway inhibitor (lipoprotein-associated coagulation inhibitor)
TMEM63A transmembrane protein 63A
TP53I11 tumor protein p53 inducible protein 11
TSC2 tuberous sclerosis 2
TSC22D4 TSC22 domain family, member 4
TULP1 tubby like protein 1
USP5 ubiquitin specific peptidase 5 (isopeptidase T)
UTRN utrophin
VAX2 ventral anterior homeobox 2
VPS9D1 VPS9 domain containing 1
WAS Wiskott-Aldrich syndrome
WDTC1 WD and tetratricopeptide repeats 1
ZCCHC14 zinc finger, CCHC domain containing 14
ZFP36L2 ZFP36 ring finger protein-like 2
ZKSCAN5 zinc finger with KRAB and SCAN domains 5
ZNF444 zinc finger protein 444
ZNF639 zinc finger protein 639

decreased expression

Symbol Name
ABCA7 ATP-binding cassette, sub-family A (ABC1), member 7
ADAM15 ADAM metallopeptidase domain 15
ADCK4 aarF domain containing kinase 4
ADPRM ADP-ribose/CDP-alcohol diphosphatase, manganese-dependent
AMT aminomethyltransferase
ARC activity-regulated cytoskeleton-associated protein
ARMC4 armadillo repeat containing 4
ATG16L1 autophagy related 16-like 1 (S. cerevisiae)
BAGE B melanoma antigen
BGLAP bone gamma-carboxyglutamate (gla) protein
BRAF B-Raf proto-oncogene, serine/threonine kinase
C17ORF53 chromosome 17 open reading frame 53
C2ORF54 chromosome 2 open reading frame 54
CALML5 calmodulin-like 5
CCBL1 cysteine conjugate-beta lyase, cytoplasmic
CCNO cyclin O
CDK3 cyclin-dependent kinase 3
CES3 carboxylesterase 3
CHRNB2 cholinergic receptor, nicotinic, beta 2 (neuronal)
CHST11 carbohydrate (chondroitin 4) sulfotransferase 11
CLDN17 claudin 17
CLGN calmegin
COPZ2 coatomer protein complex, subunit zeta 2
CORT cortistatin
DAPP1 dual adaptor of phosphotyrosine and 3-phosphoinositides
DEPDC5 DEP domain containing 5
DGCR11 DiGeorge syndrome critical region gene 11 (non-protein coding)
DIXDC1 DIX domain containing 1
DLL3 delta-like 3 (Drosophila)
DNMT3A DNA (cytosine-5-)-methyltransferase 3 alpha
DUSP9 dual specificity phosphatase 9
EFNA3 ephrin-A3
EHMT1 euchromatic histone-lysine N-methyltransferase 1
EML4 echinoderm microtubule associated protein like 4
EPB41L5 erythrocyte membrane protein band 4.1 like 5
ERCC4 excision repair cross-complementation group 4
EXOC5 exocyst complex component 5
GAMT guanidinoacetate N-methyltransferase
GNA13 guanine nucleotide binding protein (G protein), alpha 13
GTF2A1 general transcription factor IIA, 1, 19/37kDa
HIST1H2BJ histone cluster 1, H2bj
HIST1H4F histone cluster 1, H4f
HLA-DMB major histocompatibility complex, class II, DM beta
IL17RA interleukin 17 receptor A
JUNB jun B proto-oncogene
KCNN1 potassium channel, calcium activated intermediate/small conductance subfamily N alpha, member 1
KLF2 Kruppel-like factor 2
KLHL21 kelch-like family member 21
LHX6 LIM homeobox 6
LILRA6 leukocyte immunoglobulin-like receptor, subfamily A (with TM domain), member 6
LPCAT3 lysophosphatidylcholine acyltransferase 3
LRRC17 leucine rich repeat containing 17
LTBP2 latent transforming growth factor beta binding protein 2
MBNL3 muscleblind-like splicing regulator 3
MCC mutated in colorectal cancers
MCOLN1 mucolipin 1
MTA2 metastasis associated 1 family, member 2
MUC6 mucin 6, oligomeric mucus/gel-forming
NAT6 N-acetyltransferase 6 (GCN5-related)
NFKBIL1 nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor-like 1
NIPAL2 NIPA-like domain containing 2
NPIPB3 nuclear pore complex interacting protein family, member B3
OLFML2A olfactomedin-like 2A
PCDHB12 protocadherin beta 12
PCDHGB5 protocadherin gamma subfamily B, 5
PGLYRP4 peptidoglycan recognition protein 4
PGP phosphoglycolate phosphatase
PIK3R5 phosphoinositide-3-kinase, regulatory subunit 5
PLCD1 phospholipase C, delta 1
POLR2J2 polymerase (RNA) II (DNA directed) polypeptide J2
R3HCC1L R3H domain and coiled-coil containing 1-like
RAB33A RAB33A, member RAS oncogene family
RASSF2 Ras association (RalGDS/AF-6) domain family member 2
RCAN3 RCAN family member 3
RNF126P1 ring finger protein 126 pseudogene 1
RUNDC3B RUN domain containing 3B
SDS serine dehydratase
SERPINA5 serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 5
SERPINE2 serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 2
SMPDL3B sphingomyelin phosphodiesterase, acid-like 3B
SPAG7 sperm associated antigen 7
ST18 suppression of tumorigenicity 18, zinc finger
STK16 serine/threonine kinase 16
TCHH trichohyalin
TEX14 testis expressed 14
TMEM121 transmembrane protein 121
TMPRSS3 transmembrane protease, serine 3
TRIM25 tripartite motif containing 25
TRPV6 transient receptor potential cation channel, subfamily V, member 6
TTPAL tocopherol (alpha) transfer protein-like
TXLNG taxilin gamma
UNC93B1 unc-93 homolog B1 (C. elegans)
ZFHX2 zinc finger homeobox 2
ZNF37BP zinc finger protein 37B, pseudogene
ZNF510 zinc finger protein 510
ZNF573 zinc finger protein 573
ZNF701 zinc finger protein 701
ZNF747 zinc finger protein 747
ZSCAN26 zinc finger and SCAN domain containing 26