SC-58125-208 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
Similar Terms
Downloads & Tools

Genes

196 genes differentially expressed following the SC-58125-208 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
ACADS acyl-CoA dehydrogenase, C-2 to C-3 short chain
ACBD4 acyl-CoA binding domain containing 4
AKAP12 A kinase (PRKA) anchor protein 12
ANP32A acidic (leucine-rich) nuclear phosphoprotein 32 family, member A
ARFGEF2 ADP-ribosylation factor guanine nucleotide-exchange factor 2 (brefeldin A-inhibited)
ARHGAP33 Rho GTPase activating protein 33
ASMTL acetylserotonin O-methyltransferase-like
ATG12 autophagy related 12
AVL9 AVL9 homolog (S. cerevisiase)
BLK BLK proto-oncogene, Src family tyrosine kinase
BRAP BRCA1 associated protein
CA5BP1 carbonic anhydrase VB pseudogene 1
CBFA2T2 core-binding factor, runt domain, alpha subunit 2; translocated to, 2
CCDC22 coiled-coil domain containing 22
CDC42BPA CDC42 binding protein kinase alpha (DMPK-like)
CDHR2 cadherin-related family member 2
CLPS colipase, pancreatic
CLTCL1 clathrin, heavy chain-like 1
CREB3L1 cAMP responsive element binding protein 3-like 1
CRYAB crystallin, alpha B
CSH2 chorionic somatomammotropin hormone 2
CSPG5 chondroitin sulfate proteoglycan 5 (neuroglycan C)
CYP4A11 cytochrome P450, family 4, subfamily A, polypeptide 11
DLK2 delta-like 2 homolog (Drosophila)
DNAAF2 dynein, axonemal, assembly factor 2
ENOX2 ecto-NOX disulfide-thiol exchanger 2
FNBP1L formin binding protein 1-like
FOXA2 forkhead box A2
FOXN3 forkhead box N3
FOXRED2 FAD-dependent oxidoreductase domain containing 2
FXR2 fragile X mental retardation, autosomal homolog 2
GABRQ gamma-aminobutyric acid (GABA) A receptor, theta
GNS glucosamine (N-acetyl)-6-sulfatase
GOSR2 golgi SNAP receptor complex member 2
GP1BA glycoprotein Ib (platelet), alpha polypeptide
GRIN1 glutamate receptor, ionotropic, N-methyl D-aspartate 1
GSDMD gasdermin D
GSK3A glycogen synthase kinase 3 alpha
HMX1 H6 family homeobox 1
HPS1 Hermansky-Pudlak syndrome 1
IL13RA1 interleukin 13 receptor, alpha 1
IL6ST interleukin 6 signal transducer
KBTBD4 kelch repeat and BTB (POZ) domain containing 4
KIF2A kinesin heavy chain member 2A
KIR2DS1 killer cell immunoglobulin-like receptor, two domains, short cytoplasmic tail, 1
KMT2A lysine (K)-specific methyltransferase 2A
LARP4B La ribonucleoprotein domain family, member 4B
LIG3 ligase III, DNA, ATP-dependent
LIPE lipase, hormone-sensitive
LOXL3 lysyl oxidase-like 3
LZTS1 leucine zipper, putative tumor suppressor 1
MALT1 MALT1 paracaspase
MAP2K5 mitogen-activated protein kinase kinase 5
MAP3K12 mitogen-activated protein kinase kinase kinase 12
MAPK3 mitogen-activated protein kinase 3
MFGE8 milk fat globule-EGF factor 8 protein
MPPE1 metallophosphoesterase 1
NCOR2 nuclear receptor corepressor 2
NDST1 N-deacetylase/N-sulfotransferase (heparan glucosaminyl) 1
NIPAL2 NIPA-like domain containing 2
NR3C1 nuclear receptor subfamily 3, group C, member 1 (glucocorticoid receptor)
ODF2 outer dense fiber of sperm tails 2
OR2B6 olfactory receptor, family 2, subfamily B, member 6
PARG poly (ADP-ribose) glycohydrolase
PDCD4 programmed cell death 4 (neoplastic transformation inhibitor)
PDHA1 pyruvate dehydrogenase (lipoamide) alpha 1
PKNOX2 PBX/knotted 1 homeobox 2
PLEKHF1 pleckstrin homology domain containing, family F (with FYVE domain) member 1
PLIN2 perilipin 2
PML promyelocytic leukemia
PTPN2 protein tyrosine phosphatase, non-receptor type 2
PUS7L pseudouridylate synthase 7 homolog (S. cerevisiae)-like
RNF121 ring finger protein 121
RRP12 ribosomal RNA processing 12 homolog (S. cerevisiae)
SDC2 syndecan 2
SETD4 SET domain containing 4
SEZ6L seizure related 6 homolog (mouse)-like
SGSM3 small G protein signaling modulator 3
SLC10A1 solute carrier family 10 (sodium/bile acid cotransporter), member 1
SLC1A4 solute carrier family 1 (glutamate/neutral amino acid transporter), member 4
SMYD5 SMYD family member 5
SOCS2 suppressor of cytokine signaling 2
SUN2 Sad1 and UNC84 domain containing 2
SVIL supervillin
TBC1D2B TBC1 domain family, member 2B
TCF7 transcription factor 7 (T-cell specific, HMG-box)
TCN2 transcobalamin II
TGM2 transglutaminase 2
TLE1 transducin-like enhancer of split 1 (E(sp1) homolog, Drosophila)
TOB2 transducer of ERBB2, 2
TRD T cell receptor delta locus
TRPV1 transient receptor potential cation channel, subfamily V, member 1
TTC4 tetratricopeptide repeat domain 4
WDR44 WD repeat domain 44
WWC1 WW and C2 domain containing 1
ZMYM2 zinc finger, MYM-type 2
ZNF277 zinc finger protein 277
ZNF576 zinc finger protein 576

decreased expression

Symbol Name
ACTC1 actin, alpha, cardiac muscle 1
ADAM9 ADAM metallopeptidase domain 9
AEN apoptosis enhancing nuclease
ALDH1A3 aldehyde dehydrogenase 1 family, member A3
APOBEC2 apolipoprotein B mRNA editing enzyme, catalytic polypeptide-like 2
ARHGEF38 Rho guanine nucleotide exchange factor (GEF) 38
ART1 ADP-ribosyltransferase 1
ASIC4 acid sensing (proton gated) ion channel family member 4
ATG10 autophagy related 10
BCORL1 BCL6 corepressor-like 1
C19ORF40 chromosome 19 open reading frame 40
C1QTNF9B-AS1 C1QTNF9B antisense RNA 1
C8ORF60 chromosome 8 open reading frame 60
CA7 carbonic anhydrase VII
CAMK1 calcium/calmodulin-dependent protein kinase I
CAPG capping protein (actin filament), gelsolin-like
CCBL1 cysteine conjugate-beta lyase, cytoplasmic
CCDC25 coiled-coil domain containing 25
CCNJL cyclin J-like
CD83 CD83 molecule
CETN1 centrin, EF-hand protein, 1
CNNM4 cyclin and CBS domain divalent metal cation transport mediator 4
CTSF cathepsin F
CYP26A1 cytochrome P450, family 26, subfamily A, polypeptide 1
DDX51 DEAD (Asp-Glu-Ala-Asp) box polypeptide 51
DENND4C DENN/MADD domain containing 4C
DSCAM Down syndrome cell adhesion molecule
DYNC1I1 dynein, cytoplasmic 1, intermediate chain 1
EFNA3 ephrin-A3
EGFL7 EGF-like-domain, multiple 7
ERCC6L excision repair cross-complementation group 6-like
ERF Ets2 repressor factor
ERN2 endoplasmic reticulum to nucleus signaling 2
FANCF Fanconi anemia, complementation group F
GABRR2 gamma-aminobutyric acid (GABA) A receptor, rho 2
GMIP GEM interacting protein
GNA12 guanine nucleotide binding protein (G protein) alpha 12
GOLGA8B golgin A8 family, member B
GPRC5D G protein-coupled receptor, class C, group 5, member D
HHLA1 HERV-H LTR-associating 1
IFIT2 interferon-induced protein with tetratricopeptide repeats 2
IMPA1 inositol(myo)-1(or 4)-monophosphatase 1
INE1 inactivation escape 1 (non-protein coding)
IRF1 interferon regulatory factor 1
KCNN1 potassium channel, calcium activated intermediate/small conductance subfamily N alpha, member 1
KLHL28 kelch-like family member 28
LETM1 leucine zipper-EF-hand containing transmembrane protein 1
LGMN legumain
LHB luteinizing hormone beta polypeptide
MAL mal, T-cell differentiation protein
MITF microphthalmia-associated transcription factor
MT4 metallothionein 4
MVD mevalonate (diphospho) decarboxylase
NKX2-5 NK2 homeobox 5
NMNAT2 nicotinamide nucleotide adenylyltransferase 2
NT5C 5', 3'-nucleotidase, cytosolic
NUDT18 nudix (nucleoside diphosphate linked moiety X)-type motif 18
NUPL2 nucleoporin like 2
PACS1 phosphofurin acidic cluster sorting protein 1
PARP12 poly (ADP-ribose) polymerase family, member 12
PIPOX pipecolic acid oxidase
PISD phosphatidylserine decarboxylase
POLE polymerase (DNA directed), epsilon, catalytic subunit
POLR3B polymerase (RNA) III (DNA directed) polypeptide B
PRDM5 PR domain containing 5
PRMT3 protein arginine methyltransferase 3
RAB3A RAB3A, member RAS oncogene family
RAD54L RAD54-like (S. cerevisiae)
RAP1GAP2 RAP1 GTPase activating protein 2
RFNG RFNG O-fucosylpeptide 3-beta-N-acetylglucosaminyltransferase
RNF122 ring finger protein 122
RNF39 ring finger protein 39
SFXN1 sideroflexin 1
SLC22A14 solute carrier family 22, member 14
SNX10 sorting nexin 10
STARD8 StAR-related lipid transfer (START) domain containing 8
STIL SCL/TAL1 interrupting locus
SUZ12P1 suppressor of zeste 12 homolog pseudogene 1
TCIRG1 T-cell, immune regulator 1, ATPase, H+ transporting, lysosomal V0 subunit A3
TFAP4 transcription factor AP-4 (activating enhancer binding protein 4)
TIMP2 TIMP metallopeptidase inhibitor 2
TLN1 talin 1
TMEM115 transmembrane protein 115
TMEM184C transmembrane protein 184C
TMEM242 transmembrane protein 242
TMPRSS6 transmembrane protease, serine 6
TOLLIP toll interacting protein
TPSD1 tryptase delta 1
TSPAN15 tetraspanin 15
URGCP upregulator of cell proliferation
USP20 ubiquitin specific peptidase 20
VPS4B vacuolar protein sorting 4 homolog B (S. cerevisiae)
WDR4 WD repeat domain 4
ZNF189 zinc finger protein 189
ZNF586 zinc finger protein 586
ZNF91 zinc finger protein 91
ZNHIT2 zinc finger, HIT-type containing 2
ZXDC ZXD family zinc finger C