SC-58125-254 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
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Genes

197 genes differentially expressed following the SC-58125-254 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
ABCB9 ATP-binding cassette, sub-family B (MDR/TAP), member 9
ABCC3 ATP-binding cassette, sub-family C (CFTR/MRP), member 3
ABHD2 abhydrolase domain containing 2
ACADS acyl-CoA dehydrogenase, C-2 to C-3 short chain
ACAN aggrecan
AGFG2 ArfGAP with FG repeats 2
ALPK1 alpha-kinase 1
ANXA10 annexin A10
ARNTL aryl hydrocarbon receptor nuclear translocator-like
ATN1 atrophin 1
AZGP1 alpha-2-glycoprotein 1, zinc-binding
C6ORF15 chromosome 6 open reading frame 15
CASP10 caspase 10, apoptosis-related cysteine peptidase
CCDC28B coiled-coil domain containing 28B
CCHCR1 coiled-coil alpha-helical rod protein 1
CDK10 cyclin-dependent kinase 10
CHAT choline O-acetyltransferase
CHRD chordin
CLDN15 claudin 15
CLTA clathrin, light chain A
CROCCP3 ciliary rootlet coiled-coil, rootletin pseudogene 3
CST7 cystatin F (leukocystatin)
CUBN cubilin (intrinsic factor-cobalamin receptor)
DOK4 docking protein 4
DYNC1LI2 dynein, cytoplasmic 1, light intermediate chain 2
FAM107A family with sequence similarity 107, member A
FAM188A family with sequence similarity 188, member A
FAM65A family with sequence similarity 65, member A
FERMT1 fermitin family member 1
FEZ1 fasciculation and elongation protein zeta 1 (zygin I)
FKBP8 FK506 binding protein 8, 38kDa
FOLR2 folate receptor 2 (fetal)
FOXRED2 FAD-dependent oxidoreductase domain containing 2
FUT2 fucosyltransferase 2 (secretor status included)
GAL3ST4 galactose-3-O-sulfotransferase 4
GAS2L1 growth arrest-specific 2 like 1
GNB1L guanine nucleotide binding protein (G protein), beta polypeptide 1-like
GPR135 G protein-coupled receptor 135
GRM8 glutamate receptor, metabotropic 8
GVINP1 GTPase, very large interferon inducible pseudogene 1
HIST1H2AB histone cluster 1, H2ab
HOXA11 homeobox A11
HOXB2 homeobox B2
HOXD13 homeobox D13
HRASLS2 HRAS-like suppressor 2
ING4 inhibitor of growth family, member 4
LIAS lipoic acid synthetase
LMF2 lipase maturation factor 2
LTK leukocyte receptor tyrosine kinase
MAPK8 mitogen-activated protein kinase 8
MED16 mediator complex subunit 16
MICALL1 MICAL-like 1
MINK1 misshapen-like kinase 1
MMP14 matrix metallopeptidase 14 (membrane-inserted)
NAB2 NGFI-A binding protein 2 (EGR1 binding protein 2)
NFKBIL1 nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor-like 1
NOV nephroblastoma overexpressed
NPHP4 nephronophthisis 4
NUDT2 nudix (nucleoside diphosphate linked moiety X)-type motif 2
NUP214 nucleoporin 214kDa
NYNRIN NYN domain and retroviral integrase containing
PAX5 paired box 5
PCBP3 poly(rC) binding protein 3
PCYT1B phosphate cytidylyltransferase 1, choline, beta
PDXK pyridoxal (pyridoxine, vitamin B6) kinase
PKD1 polycystic kidney disease 1 (autosomal dominant)
PLAC4 placenta-specific 4
PMEL premelanosome protein
PPIL2 peptidylprolyl isomerase (cyclophilin)-like 2
PPP1R10 protein phosphatase 1, regulatory subunit 10
PRKG1 protein kinase, cGMP-dependent, type I
RAB3A RAB3A, member RAS oncogene family
RAPGEF3 Rap guanine nucleotide exchange factor (GEF) 3
RASA3 RAS p21 protein activator 3
RGS14 regulator of G-protein signaling 14
RNF41 ring finger protein 41, E3 ubiquitin protein ligase
SAG S-antigen; retina and pineal gland (arrestin)
SCAND2P SCAN domain containing 2 pseudogene
SCUBE3 signal peptide, CUB domain, EGF-like 3
SGSH N-sulfoglucosamine sulfohydrolase
SLC30A5 solute carrier family 30 (zinc transporter), member 5
SST somatostatin
TCEB2 transcription elongation factor B (SIII), polypeptide 2 (18kDa, elongin B)
TFCP2 transcription factor CP2
TICAM1 toll-like receptor adaptor molecule 1
TMEM140 transmembrane protein 140
TMEM70 transmembrane protein 70
TRAPPC12 trafficking protein particle complex 12
TRIM38 tripartite motif containing 38
TRMT2A tRNA methyltransferase 2 homolog A (S. cerevisiae)
TSPAN32 tetraspanin 32
TTR transthyretin
TXNL4A thioredoxin-like 4A
UBE2O ubiquitin-conjugating enzyme E2O
ULBP2 UL16 binding protein 2
UTY ubiquitously transcribed tetratricopeptide repeat containing, Y-linked
WIPF1 WAS/WASL interacting protein family, member 1
WNT10B wingless-type MMTV integration site family, member 10B
ZHX3 zinc fingers and homeoboxes 3

decreased expression

Symbol Name
ACBD4 acyl-CoA binding domain containing 4
ACSL5 acyl-CoA synthetase long-chain family member 5
ADPRM ADP-ribose/CDP-alcohol diphosphatase, manganese-dependent
ART3 ADP-ribosyltransferase 3
ATP6V1G2 ATPase, H+ transporting, lysosomal 13kDa, V1 subunit G2
ATP8B2 ATPase, aminophospholipid transporter, class I, type 8B, member 2
BCO1 beta-carotene oxygenase 1
BTF3P12 basic transcription factor 3 pseudogene 12
CAV3 caveolin 3
CCDC71 coiled-coil domain containing 71
CDK5RAP2 CDK5 regulatory subunit associated protein 2
CEP97 centrosomal protein 97kDa
CETN1 centrin, EF-hand protein, 1
CLDN14 claudin 14
CLEC2B C-type lectin domain family 2, member B
CTSC cathepsin C
CXADR coxsackie virus and adenovirus receptor
CYP26A1 cytochrome P450, family 26, subfamily A, polypeptide 1
CYP2J2 cytochrome P450, family 2, subfamily J, polypeptide 2
CYSLTR2 cysteinyl leukotriene receptor 2
DAGLA diacylglycerol lipase, alpha
DBR1 debranching RNA lariats 1
DCP1A decapping mRNA 1A
DFNA5 deafness, autosomal dominant 5
DNAJC24 DnaJ (Hsp40) homolog, subfamily C, member 24
DNASE1L2 deoxyribonuclease I-like 2
ECE2 endothelin converting enzyme 2
ERI3 ERI1 exoribonuclease family member 3
ETS1 v-ets avian erythroblastosis virus E26 oncogene homolog 1
FAM110D family with sequence similarity 110, member D
FARP2 FERM, RhoGEF and pleckstrin domain protein 2
FGF6 fibroblast growth factor 6
FHL3 four and a half LIM domains 3
FIP1L1 factor interacting with PAPOLA and CPSF1
FOXC1 forkhead box C1
GABRG2 gamma-aminobutyric acid (GABA) A receptor, gamma 2
GABRP gamma-aminobutyric acid (GABA) A receptor, pi
GDF2 growth differentiation factor 2
GJB1 gap junction protein, beta 1, 32kDa
GLMN glomulin, FKBP associated protein
GMPPB GDP-mannose pyrophosphorylase B
GRHL2 grainyhead-like 2 (Drosophila)
GUCA2A guanylate cyclase activator 2A (guanylin)
HERC3 HECT and RLD domain containing E3 ubiquitin protein ligase 3
IGFALS insulin-like growth factor binding protein, acid labile subunit
IL7R interleukin 7 receptor
JMJD1C jumonji domain containing 1C
KBTBD4 kelch repeat and BTB (POZ) domain containing 4
KCNC1 potassium channel, voltage gated Shaw related subfamily C, member 1
KIAA0509 uncharacterized LOC57242
KIFAP3 kinesin-associated protein 3
KIR2DS1 killer cell immunoglobulin-like receptor, two domains, short cytoplasmic tail, 1
KIR3DS1 killer cell immunoglobulin-like receptor, three domains, short cytoplasmic tail, 1
KLRK1 killer cell lectin-like receptor subfamily K, member 1
LHX6 LIM homeobox 6
LSM1 LSM1, U6 small nuclear RNA associated
LY6G6D lymphocyte antigen 6 complex, locus G6D
MEIS2 Meis homeobox 2
MFGE8 milk fat globule-EGF factor 8 protein
MICU2 mitochondrial calcium uptake 2
MIR600HG MIR600 host gene
MMP3 matrix metallopeptidase 3
MTERF4 mitochondrial transcription termination factor 4
MTL5 metallothionein-like 5, testis-specific (tesmin)
NDN necdin, melanoma antigen (MAGE) family member
OGFRL1 opioid growth factor receptor-like 1
PARG poly (ADP-ribose) glycohydrolase
PCDHA5 protocadherin alpha 5
PISD phosphatidylserine decarboxylase
PODNL1 podocan-like 1
PRDM14 PR domain containing 14
PRG3 proteoglycan 3
PRRG2 proline rich Gla (G-carboxyglutamic acid) 2
PSAT1 phosphoserine aminotransferase 1
PZP pregnancy-zone protein
RAB33B RAB33B, member RAS oncogene family
RAPGEFL1 Rap guanine nucleotide exchange factor (GEF)-like 1
RBM41 RNA binding motif protein 41
RDH5 retinol dehydrogenase 5 (11-cis/9-cis)
RDH8 retinol dehydrogenase 8 (all-trans)
RHBDF2 rhomboid 5 homolog 2 (Drosophila)
SAA4 serum amyloid A4, constitutive
SERPINB10 serpin peptidase inhibitor, clade B (ovalbumin), member 10
SLC8B1 solute carrier family 8 (sodium/lithium/calcium exchanger), member B1
SNORA21 small nucleolar RNA, H/ACA box 21
SPAG4 sperm associated antigen 4
SPP1 secreted phosphoprotein 1
TANC2 tetratricopeptide repeat, ankyrin repeat and coiled-coil containing 2
TMEM176A transmembrane protein 176A
TMSB4Y thymosin beta 4, Y-linked
TRAC T cell receptor alpha constant
TSPAN7 tetraspanin 7
TUBGCP5 tubulin, gamma complex associated protein 5
VCPIP1 valosin containing protein (p97)/p47 complex interacting protein 1
WNT2 wingless-type MMTV integration site family member 2
ZBTB10 zinc finger and BTB domain containing 10
ZBTB44 zinc finger and BTB domain containing 44
ZNF267 zinc finger protein 267