SC-58125-542 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
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Genes

199 genes differentially expressed following the SC-58125-542 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
ACOT11 acyl-CoA thioesterase 11
ACRV1 acrosomal vesicle protein 1
AEN apoptosis enhancing nuclease
AFF2 AF4/FMR2 family, member 2
AKR1C1 aldo-keto reductase family 1, member C1
ALDH2 aldehyde dehydrogenase 2 family (mitochondrial)
AP2A2 adaptor-related protein complex 2, alpha 2 subunit
ARIH2 ariadne RBR E3 ubiquitin protein ligase 2
ARVCF armadillo repeat gene deleted in velocardiofacial syndrome
ASF1A anti-silencing function 1A histone chaperone
ATF6 activating transcription factor 6
ATF6B activating transcription factor 6 beta
ATP2C1 ATPase, Ca++ transporting, type 2C, member 1
C2CD2L C2CD2-like
C4ORF29 chromosome 4 open reading frame 29
CACFD1 calcium channel flower domain containing 1
CCNJ cyclin J
CD44 CD44 molecule (Indian blood group)
CER1 cerberus 1, DAN family BMP antagonist
CETN1 centrin, EF-hand protein, 1
CHD3 chromodomain helicase DNA binding protein 3
CLDN17 claudin 17
CSF1 colony stimulating factor 1 (macrophage)
CTNS cystinosin, lysosomal cystine transporter
CYP2C9 cytochrome P450, family 2, subfamily C, polypeptide 9
EIF4G3 eukaryotic translation initiation factor 4 gamma, 3
ENC1 ectodermal-neural cortex 1 (with BTB domain)
FGF4 fibroblast growth factor 4
FOLR1 folate receptor 1 (adult)
FSCN3 fascin actin-bundling protein 3, testicular
GGA2 golgi-associated, gamma adaptin ear containing, ARF binding protein 2
GOLGA1 golgin A1
GP1BA glycoprotein Ib (platelet), alpha polypeptide
GPR107 G protein-coupled receptor 107
GRIP2 glutamate receptor interacting protein 2
GSK3A glycogen synthase kinase 3 alpha
GSTA4 glutathione S-transferase alpha 4
HDAC7 histone deacetylase 7
HGSNAT heparan-alpha-glucosaminide N-acetyltransferase
IGSF6 immunoglobulin superfamily, member 6
JMJD4 jumonji domain containing 4
KDELR3 KDEL (Lys-Asp-Glu-Leu) endoplasmic reticulum protein retention receptor 3
KIF18A kinesin family member 18A
KIR2DL3 killer cell immunoglobulin-like receptor, two domains, long cytoplasmic tail, 3
KIR2DL5A killer cell immunoglobulin-like receptor, two domains, long cytoplasmic tail, 5A
KLHL21 kelch-like family member 21
KPNB1 karyopherin (importin) beta 1
LECT1 leukocyte cell derived chemotaxin 1
LINC00339 long intergenic non-protein coding RNA 339
MAPK3 mitogen-activated protein kinase 3
MAST2 microtubule associated serine/threonine kinase 2
MBD3 methyl-CpG binding domain protein 3
MBD5 methyl-CpG binding domain protein 5
MED12 mediator complex subunit 12
MFAP2 microfibrillar-associated protein 2
MRC2 mannose receptor, C type 2
MYL10 myosin, light chain 10, regulatory
MYO1B myosin IB
N4BP2L1 NEDD4 binding protein 2-like 1
NCS1 neuronal calcium sensor 1
NDRG2 NDRG family member 2
NFATC4 nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 4
NMT1 N-myristoyltransferase 1
NPAT nuclear protein, ataxia-telangiectasia locus
OSGEPL1 O-sialoglycoprotein endopeptidase-like 1
PIGR polymeric immunoglobulin receptor
PIK3IP1 phosphoinositide-3-kinase interacting protein 1
PLK3 polo-like kinase 3
PPP1R17 protein phosphatase 1, regulatory subunit 17
PPP2R1B protein phosphatase 2, regulatory subunit A, beta
PRDM4 PR domain containing 4
PRIM2 primase, DNA, polypeptide 2 (58kDa)
PRKCQ protein kinase C, theta
PSMD9 proteasome (prosome, macropain) 26S subunit, non-ATPase, 9
PTPN18 protein tyrosine phosphatase, non-receptor type 18 (brain-derived)
PTPRJ protein tyrosine phosphatase, receptor type, J
PTPRT protein tyrosine phosphatase, receptor type, T
RIMS2 regulating synaptic membrane exocytosis 2
RPS28 ribosomal protein S28
RRP12 ribosomal RNA processing 12 homolog (S. cerevisiae)
SETD8 SET domain containing (lysine methyltransferase) 8
SIRPB1 signal-regulatory protein beta 1
SLC23A2 solute carrier family 23 (ascorbic acid transporter), member 2
SLC2A1 solute carrier family 2 (facilitated glucose transporter), member 1
SMG7 SMG7 nonsense mediated mRNA decay factor
SPP2 secreted phosphoprotein 2, 24kDa
ST6GAL1 ST6 beta-galactosamide alpha-2,6-sialyltranferase 1
SYNJ2 synaptojanin 2
TCOF1 Treacher Collins-Franceschetti syndrome 1
THADA thyroid adenoma associated
TMEM184B transmembrane protein 184B
TNFSF9 tumor necrosis factor (ligand) superfamily, member 9
TP63 tumor protein p63
TRAM2 translocation associated membrane protein 2
UBQLN4 ubiquilin 4
USF2 upstream transcription factor 2, c-fos interacting
WRN Werner syndrome, RecQ helicase-like
YKT6 YKT6 v-SNARE homolog (S. cerevisiae)
ZFYVE9 zinc finger, FYVE domain containing 9
ZKSCAN1 zinc finger with KRAB and SCAN domains 1

decreased expression

Symbol Name
ANKRD40 ankyrin repeat domain 40
APOC2 apolipoprotein C-II
ARF5 ADP-ribosylation factor 5
ARG1 arginase 1
AVPR1B arginine vasopressin receptor 1B
BIK BCL2-interacting killer (apoptosis-inducing)
BSCL2 Berardinelli-Seip congenital lipodystrophy 2 (seipin)
C3 complement component 3
C9ORF114 chromosome 9 open reading frame 114
CA5BP1 carbonic anhydrase VB pseudogene 1
CARHSP1 calcium regulated heat stable protein 1, 24kDa
CCDC53 coiled-coil domain containing 53
CCDC71 coiled-coil domain containing 71
CCDC94 coiled-coil domain containing 94
CCL2 chemokine (C-C motif) ligand 2
CHML choroideremia-like (Rab escort protein 2)
CMC2 C-x(9)-C motif containing 2
COG7 component of oligomeric golgi complex 7
CORT cortistatin
CREB3 cAMP responsive element binding protein 3
CTSE cathepsin E
CYB5R3 cytochrome b5 reductase 3
CYBRD1 cytochrome b reductase 1
CYP20A1 cytochrome P450, family 20, subfamily A, polypeptide 1
CYSLTR2 cysteinyl leukotriene receptor 2
DDN dendrin
DERL2 derlin 2
DOC2B double C2-like domains, beta
DOK3 docking protein 3
DYRK4 dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 4
EMC9 ER membrane protein complex subunit 9
ENDOG endonuclease G
EPHA2 EPH receptor A2
FAM222B family with sequence similarity 222, member B
FOXRED2 FAD-dependent oxidoreductase domain containing 2
GBAP1 glucosidase, beta, acid pseudogene 1
GPX2 glutathione peroxidase 2
HDAC5 histone deacetylase 5
HIST1H1C histone cluster 1, H1c
HIST1H4J histone cluster 1, H4j
IFIT2 interferon-induced protein with tetratricopeptide repeats 2
IFITM3 interferon induced transmembrane protein 3
KLF1 Kruppel-like factor 1 (erythroid)
KLHL25 kelch-like family member 25
KRI1 KRI1 homolog (S. cerevisiae)
LGALS1 lectin, galactoside-binding, soluble, 1
LIAS lipoic acid synthetase
LIN7A lin-7 homolog A (C. elegans)
LLGL2 lethal giant larvae homolog 2 (Drosophila)
LMTK1 lemur tail kinase 1
LOC390998 ribosomal protein L10 pseudogene
MAGEC1 melanoma antigen family C1
MAPKBP1 mitogen-activated protein kinase binding protein 1
MICA MHC class I polypeptide-related sequence A
MIP major intrinsic protein of lens fiber
MOCS3 molybdenum cofactor synthesis 3
MPC1 mitochondrial pyruvate carrier 1
MPDU1 mannose-P-dolichol utilization defect 1
MRPL33 mitochondrial ribosomal protein L33
MRPL35 mitochondrial ribosomal protein L35
MT1HL1 metallothionein 1H-like 1
NAT6 N-acetyltransferase 6 (GCN5-related)
NCAPH non-SMC condensin I complex, subunit H
NDUFA3 NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 3, 9kDa
NDUFA4 NDUFA4, mitochondrial complex associated
NFKBIA nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha
NINJ1 ninjurin 1
NUDT1 nudix (nucleoside diphosphate linked moiety X)-type motif 1
OBFC1 oligonucleotide/oligosaccharide-binding fold containing 1
OR2F1 olfactory receptor, family 2, subfamily F, member 1 (gene/pseudogene)
PMPCB peptidase (mitochondrial processing) beta
PMS2P5 postmeiotic segregation increased 2 pseudogene 5
POLD4 polymerase (DNA-directed), delta 4, accessory subunit
PSMC4 proteasome (prosome, macropain) 26S subunit, ATPase, 4
PTCD2 pentatricopeptide repeat domain 2
PUS7L pseudouridylate synthase 7 homolog (S. cerevisiae)-like
RHBDF2 rhomboid 5 homolog 2 (Drosophila)
RPL35 ribosomal protein L35
RPL39L ribosomal protein L39-like
S100A12 S100 calcium binding protein A12
SH3GL1 SH3-domain GRB2-like 1
SLAMF7 SLAM family member 7
SLC10A3 solute carrier family 10, member 3
SMA4 glucuronidase, beta pseudogene
SMO smoothened, frizzled class receptor
SNAP29 synaptosomal-associated protein, 29kDa
SPRR3 small proline-rich protein 3
SSTR4 somatostatin receptor 4
SULT2B1 sulfotransferase family, cytosolic, 2B, member 1
TEX13B testis expressed 13B
THRAP3 thyroid hormone receptor associated protein 3
TIMM22 translocase of inner mitochondrial membrane 22 homolog (yeast)
TINF2 TERF1 (TRF1)-interacting nuclear factor 2
TMED1 transmembrane emp24 protein transport domain containing 1
TMEM209 transmembrane protein 209
TSPYL2 TSPY-like 2
TSSC4 tumor suppressing subtransferable candidate 4
UPK3A uroplakin 3A
ZNF816 zinc finger protein 816