SCC-15 Gene Set

Dataset COSMIC Cell Line Gene Mutation Profiles
Category genomics
Type cell line
Description Human tongue squamous cell carcinoma cell line. (BRENDA Tissue and Enzyme Source Ontology, BTO_0005102)
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Genes

309 genes mutated in the SCC-15 cell line from the COSMIC Cell Line Gene Mutation Profiles dataset.

Symbol Name
ABCA2 ATP-binding cassette, sub-family A (ABC1), member 2
ADAMTS8 ADAM metallopeptidase with thrombospondin type 1 motif, 8
ADAMTSL2 ADAMTS-like 2
AHSG alpha-2-HS-glycoprotein
AMBN ameloblastin (enamel matrix protein)
AMDHD1 amidohydrolase domain containing 1
ANKRD30A ankyrin repeat domain 30A
ANKRD30B ankyrin repeat domain 30B
ARAP1 ArfGAP with RhoGAP domain, ankyrin repeat and PH domain 1
ARHGAP15 Rho GTPase activating protein 15
ARHGAP27 Rho GTPase activating protein 27
ARID1A AT rich interactive domain 1A (SWI-like)
ARID5A AT rich interactive domain 5A (MRF1-like)
ARPP19 cAMP-regulated phosphoprotein, 19kDa
ASCL3 achaete-scute family bHLH transcription factor 3
ATP7A ATPase, Cu++ transporting, alpha polypeptide
ATR ATR serine/threonine kinase
B4GALT7 xylosylprotein beta 1,4-galactosyltransferase, polypeptide 7
BCL11B B-cell CLL/lymphoma 11B (zinc finger protein)
BCR breakpoint cluster region
BRINP2 bone morphogenetic protein/retinoic acid inducible neural-specific 2
BRPF3 bromodomain and PHD finger containing, 3
BUB1B BUB1 mitotic checkpoint serine/threonine kinase B
C1S complement component 1, s subcomponent
CACNA1F calcium channel, voltage-dependent, L type, alpha 1F subunit
CAGE1 cancer antigen 1
CCDC60 coiled-coil domain containing 60
CD276 CD276 molecule
CD300LB CD300 molecule-like family member b
CD33 CD33 molecule
CD86 CD86 molecule
CDC50A cell division cycle 50 P4-ATPase accessory subunit A
CDH1 cadherin 1, type 1, E-cadherin (epithelial)
CDH2 cadherin 2, type 1, N-cadherin (neuronal)
CDKN2A cyclin-dependent kinase inhibitor 2A
CEP72 centrosomal protein 72kDa
CEP83 centrosomal protein 83kDa
CHAT choline O-acetyltransferase
CHD9 chromodomain helicase DNA binding protein 9
CLCNKB chloride channel, voltage-sensitive Kb
CLK1 CDC-like kinase 1
CLUH clustered mitochondria (cluA/CLU1) homolog
CNNM2 cyclin and CBS domain divalent metal cation transport mediator 2
CNTFR ciliary neurotrophic factor receptor
COL11A1 collagen, type XI, alpha 1
COL27A1 collagen, type XXVII, alpha 1
CSMD1 CUB and Sushi multiple domains 1
CSMD2 CUB and Sushi multiple domains 2
CTBP2 C-terminal binding protein 2
CTU2 cytosolic thiouridylase subunit 2 homolog (S. pombe)
CUBN cubilin (intrinsic factor-cobalamin receptor)
CYLD cylindromatosis (turban tumor syndrome)
DBNL drebrin-like
DCBLD2 discoidin, CUB and LCCL domain containing 2
DCLK1 doublecortin-like kinase 1
DCST2 DC-STAMP domain containing 2
DDN dendrin
DDOST dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit (non-catalytic)
DDX11 DEAD/H (Asp-Glu-Ala-Asp/His) box helicase 11
DEFB115 defensin, beta 115
DENND4A DENN/MADD domain containing 4A
DHRS12 dehydrogenase/reductase (SDR family) member 12
DHX35 DEAH (Asp-Glu-Ala-His) box polypeptide 35
DIAPH2 diaphanous-related formin 2
DLL4 delta-like 4 (Drosophila)
DNAH11 dynein, axonemal, heavy chain 11
DPYSL5 dihydropyrimidinase-like 5
DTNB dystrobrevin, beta
DUOX2 dual oxidase 2
EARS2 glutamyl-tRNA synthetase 2, mitochondrial
EGFL7 EGF-like-domain, multiple 7
EIF3A eukaryotic translation initiation factor 3, subunit A
EIF4G1 eukaryotic translation initiation factor 4 gamma, 1
EP400 E1A binding protein p400
EPB42 erythrocyte membrane protein band 4.2
EPHB2 EPH receptor B2
EPM2AIP1 EPM2A (laforin) interacting protein 1
ERCC6 excision repair cross-complementation group 6
ERG v-ets avian erythroblastosis virus E26 oncogene homolog
ESPL1 extra spindle pole bodies homolog 1 (S. cerevisiae)
ESPN espin
EXOC4 exocyst complex component 4
FAM214A family with sequence similarity 214, member A
FAT1 FAT atypical cadherin 1
FAT4 FAT atypical cadherin 4
FCGR1B Fc fragment of IgG, high affinity Ib, receptor (CD64)
FEN1 flap structure-specific endonuclease 1
FGF9 fibroblast growth factor 9
FLG filaggrin
FLNA filamin A, alpha
FOSL1 FOS-like antigen 1
FPR1 formyl peptide receptor 1
FREM1 FRAS1 related extracellular matrix 1
FREM3 FRAS1 related extracellular matrix 3
FRG2C FSHD region gene 2 family, member C
FSTL5 follistatin-like 5
GABRB2 gamma-aminobutyric acid (GABA) A receptor, beta 2
GLUD2 glutamate dehydrogenase 2
GOLGA2 golgin A2
GOLGA8IP golgin A8 family, member I, pseudogene
GPR78 G protein-coupled receptor 78
GTF2I general transcription factor IIi
HCAR2 hydroxycarboxylic acid receptor 2
HCLS1 hematopoietic cell-specific Lyn substrate 1
HELZ2 helicase with zinc finger 2, transcriptional coactivator
HLA-DQB1 major histocompatibility complex, class II, DQ beta 1
HTR3D 5-hydroxytryptamine (serotonin) receptor 3D, ionotropic
IFT88 intraflagellar transport 88
IL13 interleukin 13
IL7R interleukin 7 receptor
IMP4 IMP4, U3 small nucleolar ribonucleoprotein
IPO4 importin 4
IRX5 iroquois homeobox 5
ITGA10 integrin, alpha 10
ITPR3 inositol 1,4,5-trisphosphate receptor, type 3
IVD isovaleryl-CoA dehydrogenase
KAT6B K(lysine) acetyltransferase 6B
KCNH5 potassium channel, voltage gated eag related subfamily H, member 5
KCNK5 potassium channel, two pore domain subfamily K, member 5
KDM8 lysine (K)-specific demethylase 8
KIAA0430 KIAA0430
KIF21A kinesin family member 21A
KIR2DL4 killer cell immunoglobulin-like receptor, two domains, long cytoplasmic tail, 4
KLHL42 kelch-like family member 42
KMT2D lysine (K)-specific methyltransferase 2D
KPRP keratinocyte proline-rich protein
KRT79 keratin 79, type II
LAMB4 laminin, beta 4
LANCL1 LanC lantibiotic synthetase component C-like 1 (bacterial)
LCN2 lipocalin 2
LCT lactase
LDB3 LIM domain binding 3
LILRA2 leukocyte immunoglobulin-like receptor, subfamily A (with TM domain), member 2
LRFN2 leucine rich repeat and fibronectin type III domain containing 2
LRRC37A2 leucine rich repeat containing 37, member A2
LRRIQ1 leucine-rich repeats and IQ motif containing 1
LTBP1 latent transforming growth factor beta binding protein 1
LYZ lysozyme
LYZL1 lysozyme-like 1
M6PR mannose-6-phosphate receptor (cation dependent)
MACROD2 MACRO domain containing 2
MAP1S microtubule-associated protein 1S
MAP3K6 mitogen-activated protein kinase kinase kinase 6
MED13 mediator complex subunit 13
MFSD9 major facilitator superfamily domain containing 9
MPP5 membrane protein, palmitoylated 5 (MAGUK p55 subfamily member 5)
MRM1 mitochondrial rRNA methyltransferase 1 homolog (S. cerevisiae)
MRPL40 mitochondrial ribosomal protein L40
MTHFD1 methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 1, methenyltetrahydrofolate cyclohydrolase, formyltetrahydrofolate synthetase
MTMR4 myotubularin related protein 4
MTRR 5-methyltetrahydrofolate-homocysteine methyltransferase reductase
MUC12 mucin 12, cell surface associated
MUC21 mucin 21, cell surface associated
MUC4 mucin 4, cell surface associated
MUC5AC mucin 5AC, oligomeric mucus/gel-forming
MUC5B mucin 5B, oligomeric mucus/gel-forming
MYBBP1A MYB binding protein (P160) 1a
MYH1 myosin, heavy chain 1, skeletal muscle, adult
MYH4 myosin, heavy chain 4, skeletal muscle
MYO1F myosin IF
MYO3B myosin IIIB
MYO5C myosin VC
MYO7B myosin VIIB
MYOM3 myomesin 3
NBPF10 neuroblastoma breakpoint family, member 10
NCAPD2 non-SMC condensin I complex, subunit D2
NCAPD3 non-SMC condensin II complex, subunit D3
NCAPG2 non-SMC condensin II complex, subunit G2
NDFIP1 Nedd4 family interacting protein 1
NEDD4 neural precursor cell expressed, developmentally down-regulated 4, E3 ubiquitin protein ligase
NFAT5 nuclear factor of activated T-cells 5, tonicity-responsive
NLRP2 NLR family, pyrin domain containing 2
NOP14 NOP14 nucleolar protein
NOTCH3 notch 3
NR4A1 nuclear receptor subfamily 4, group A, member 1
NRXN3 neurexin 3
NUP155 nucleoporin 155kDa
OLFM3 olfactomedin 3
OR10A6 olfactory receptor, family 10, subfamily A, member 6 (gene/pseudogene)
OR1L6 olfactory receptor, family 1, subfamily L, member 6
OR51E1 olfactory receptor, family 51, subfamily E, member 1
OR5M8 olfactory receptor, family 5, subfamily M, member 8
OR7G1 olfactory receptor, family 7, subfamily G, member 1
OR8A1 olfactory receptor, family 8, subfamily A, member 1
OTOG otogelin
OTOGL otogelin-like
PAH phenylalanine hydroxylase
PC pyruvate carboxylase
PCCA propionyl CoA carboxylase, alpha polypeptide
PCDH17 protocadherin 17
PCDHB16 protocadherin beta 16
PCDHG@ protocadherin gamma cluster
PCDHGA1 protocadherin gamma subfamily A, 1
PCDHGA10 protocadherin gamma subfamily A, 10
PCDHGA11 protocadherin gamma subfamily A, 11
PCDHGA12 protocadherin gamma subfamily A, 12
PCDHGA3 protocadherin gamma subfamily A, 3
PCDHGA4 protocadherin gamma subfamily A, 4
PCDHGA5 protocadherin gamma subfamily A, 5
PCDHGA6 protocadherin gamma subfamily A, 6
PCDHGA7 protocadherin gamma subfamily A, 7
PCDHGA8 protocadherin gamma subfamily A, 8
PCDHGA9 protocadherin gamma subfamily A, 9
PCDHGB1 protocadherin gamma subfamily B, 1
PCDHGB2 protocadherin gamma subfamily B, 2
PCDHGB3 protocadherin gamma subfamily B, 3
PCDHGB4 protocadherin gamma subfamily B, 4
PCDHGB6 protocadherin gamma subfamily B, 6
PCDHGB7 protocadherin gamma subfamily B, 7
PCDHGC3 protocadherin gamma subfamily C, 3
PCDHGC4 protocadherin gamma subfamily C, 4
PCDHGC5 protocadherin gamma subfamily C, 5
PCLO piccolo presynaptic cytomatrix protein
PCSK6 proprotein convertase subtilisin/kexin type 6
PDE4D phosphodiesterase 4D, cAMP-specific
PDIA4 protein disulfide isomerase family A, member 4
PFKP phosphofructokinase, platelet
PGLS 6-phosphogluconolactonase
PIEZO1 piezo-type mechanosensitive ion channel component 1
PIGS phosphatidylinositol glycan anchor biosynthesis, class S
PIK3R3 phosphoinositide-3-kinase, regulatory subunit 3 (gamma)
PLCB1 phospholipase C, beta 1 (phosphoinositide-specific)
PLCE1 phospholipase C, epsilon 1
PLCL1 phospholipase C-like 1
PLCZ1 phospholipase C, zeta 1
PLEKHA6 pleckstrin homology domain containing, family A member 6
PLK4 polo-like kinase 4
PNPLA7 patatin-like phospholipase domain containing 7
POTED POTE ankyrin domain family, member D
PPL periplakin
PPP1R9A protein phosphatase 1, regulatory subunit 9A
PRR23A proline rich 23A
PTGIS prostaglandin I2 (prostacyclin) synthase
PTPRC protein tyrosine phosphatase, receptor type, C
PTPRF protein tyrosine phosphatase, receptor type, F
RALGPS2 Ral GEF with PH domain and SH3 binding motif 2
RB1CC1 RB1-inducible coiled-coil 1
RBMXL2 RNA binding motif protein, X-linked-like 2
RCAN2 regulator of calcineurin 2
REC8 REC8 meiotic recombination protein
RFNG RFNG O-fucosylpeptide 3-beta-N-acetylglucosaminyltransferase
RHOBTB3 Rho-related BTB domain containing 3
RMND1 required for meiotic nuclear division 1 homolog (S. cerevisiae)
ROCK1 Rho-associated, coiled-coil containing protein kinase 1
RRP12 ribosomal RNA processing 12 homolog (S. cerevisiae)
RUNX2 runt-related transcription factor 2
SACK1H scaffolding CK1 anchoring protein H
SAMD4B sterile alpha motif domain containing 4B
SASH1 SAM and SH3 domain containing 1
SCN9A sodium channel, voltage gated, type IX alpha subunit
SECISBP2 SECIS binding protein 2
SERPINA2 serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 2 (gene/pseudogene)
SH3TC2 SH3 domain and tetratricopeptide repeats 2
SI sucrase-isomaltase (alpha-glucosidase)
SLA2 Src-like-adaptor 2
SLC22A10 solute carrier family 22, member 10
SLC24A2 solute carrier family 24 (sodium/potassium/calcium exchanger), member 2
SLC39A3 solute carrier family 39 (zinc transporter), member 3
SLC4A4 solute carrier family 4 (sodium bicarbonate cotransporter), member 4
SLC7A2 solute carrier family 7 (cationic amino acid transporter, y+ system), member 2
SLC8A1 solute carrier family 8 (sodium/calcium exchanger), member 1
SLC9A8 solute carrier family 9, subfamily A (NHE8, cation proton antiporter 8), member 8
SLITRK1 SLIT and NTRK-like family, member 1
SMAD2 SMAD family member 2
SMARCC1 SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily c, member 1
SMOC1 SPARC related modular calcium binding 1
SNX4 sorting nexin 4
SORBS3 sorbin and SH3 domain containing 3
SOX7 SRY (sex determining region Y)-box 7
SPOCD1 SPOC domain containing 1
SPTB spectrin, beta, erythrocytic
SPTBN4 spectrin, beta, non-erythrocytic 4
STAT4 signal transducer and activator of transcription 4
SYCP2L synaptonemal complex protein 2-like
TCF23 transcription factor 23
TDG thymine-DNA glycosylase
TEX2 testis expressed 2
TIGD5 tigger transposable element derived 5
TMC5 transmembrane channel-like 5
TP53 tumor protein p53
TRIM41 tripartite motif containing 41
TRIO trio Rho guanine nucleotide exchange factor
TRPM4 transient receptor potential cation channel, subfamily M, member 4
TRRAP transformation/transcription domain-associated protein
TSHZ2 teashirt zinc finger homeobox 2
TSPAN2 tetraspanin 2
TTC9C tetratricopeptide repeat domain 9C
USP38 ubiquitin specific peptidase 38
USP47 ubiquitin specific peptidase 47
UTRN utrophin
VPS8 vacuolar protein sorting 8 homolog (S. cerevisiae)
VRTN vertebrae development associated
WDR31 WD repeat domain 31
WFS1 Wolfram syndrome 1 (wolframin)
XAB2 XPA binding protein 2
XIRP2 xin actin binding repeat containing 2
YARS2 tyrosyl-tRNA synthetase 2, mitochondrial
YBX1 Y box binding protein 1
ZAK sterile alpha motif and leucine zipper containing kinase AZK
ZDHHC11 zinc finger, DHHC-type containing 11
ZFP64 ZFP64 zinc finger protein
ZNF256 zinc finger protein 256
ZNF462 zinc finger protein 462
ZNF48 zinc finger protein 48
ZNF493 zinc finger protein 493
ZNF737 zinc finger protein 737
ZNF90 zinc finger protein 90
ZPBP zona pellucida binding protein
ZSWIM6 zinc finger, SWIM-type containing 6