SCC-15 Gene Set

Dataset GDSC Cell Line Gene Expression Profiles
Category transcriptomics
Type cell line
Description Human tongue squamous cell carcinoma cell line. (BRENDA Tissue and Enzyme Source Ontology, BTO_0005102)
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Genes

225 genes with high or low expression in SCC-15 relative to other cell lines from the GDSC Cell Line Gene Expression Profiles dataset.

high expression

Symbol Name Standardized Value
CCT6A chaperonin containing TCP1, subunit 6A (zeta 1) 2.1977
DUSP11 dual specificity phosphatase 11 (RNA/RNP complex 1-interacting) 2.13346
TUBB6 tubulin, beta 6 class V 2.10708
TCOF1 Treacher Collins-Franceschetti syndrome 1 2.05858
RALA v-ral simian leukemia viral oncogene homolog A (ras related) 2.04735
PSMD2 proteasome (prosome, macropain) 26S subunit, non-ATPase, 2 2.02692
RCE1 Ras converting CAAX endopeptidase 1 2.00724
CRYGB crystallin, gamma B 1.97928
DRAP1 DR1-associated protein 1 (negative cofactor 2 alpha) 1.91587
MMP9 matrix metallopeptidase 9 1.91462
SART1 squamous cell carcinoma antigen recognized by T cells 1.91029
BIRC2 baculoviral IAP repeat containing 2 1.90375
MOCS2 molybdenum cofactor synthesis 2 1.89862
SEC61G Sec61 gamma subunit 1.88793
CTTN cortactin 1.88787
TIMM23 translocase of inner mitochondrial membrane 23 homolog (yeast) 1.88737
LAMC2 laminin, gamma 2 1.88046
CHCHD2 coiled-coil-helix-coiled-coil-helix domain containing 2 1.87693
KRT6B keratin 6B, type II 1.84425
MYOT myotilin 1.81388
MAP2K1 mitogen-activated protein kinase kinase 1 1.79118
ANXA2 annexin A2 1.7875
SPDL1 spindle apparatus coiled-coil protein 1 1.76233
MRPS17 mitochondrial ribosomal protein S17 1.75582
NDUFS4 NADH dehydrogenase (ubiquinone) Fe-S protein 4, 18kDa (NADH-coenzyme Q reductase) 1.73637
CFAP70 cilia and flagella associated protein 70 1.72992
SEPT7 septin 7 1.72782
ANXA2P2 annexin A2 pseudogene 2 1.71923
LAMA3 laminin, alpha 3 1.71292
PTPRK protein tyrosine phosphatase, receptor type, K 1.69478
FAM120A family with sequence similarity 120A 1.6906
COPS3 COP9 signalosome subunit 3 1.68407
NUDT15 nudix (nucleoside diphosphate linked moiety X)-type motif 15 1.67606
ECHDC1 ethylmalonyl-CoA decarboxylase 1 1.6702
SERPINB2 serpin peptidase inhibitor, clade B (ovalbumin), member 2 1.66561
LANCL2 LanC lantibiotic synthetase component C-like 2 (bacterial) 1.66324
SLC31A2 solute carrier family 31 (copper transporter), member 2 1.66318
BIRC3 baculoviral IAP repeat containing 3 1.65378
GPN1 GPN-loop GTPase 1 1.6529
ITGB1BP1 integrin beta 1 binding protein 1 1.65015
KCNJ15 potassium channel, inwardly rectifying subfamily J, member 15 1.63828
EIF2S1 eukaryotic translation initiation factor 2, subunit 1 alpha, 35kDa 1.61148
PFN1 profilin 1 1.60996
PSMD5 proteasome (prosome, macropain) 26S subunit, non-ATPase, 5 1.59063
BANF1 barrier to autointegration factor 1 1.58862
MT1H metallothionein 1H 1.5822
MAPK6 mitogen-activated protein kinase 6 1.57403
CCNB1 cyclin B1 1.56393
INHBA inhibin, beta A 1.56236
MRPL22 mitochondrial ribosomal protein L22 1.56195
NEDD4 neural precursor cell expressed, developmentally down-regulated 4, E3 ubiquitin protein ligase 1.55861
ARPP19 cAMP-regulated phosphoprotein, 19kDa 1.54579
FAF2 Fas associated factor family member 2 1.54556
SOX15 SRY (sex determining region Y)-box 15 1.54225
HSF2BP heat shock transcription factor 2 binding protein 1.53892
DERL2 derlin 2 1.52512
CLCF1 cardiotrophin-like cytokine factor 1 1.5196
PELO pelota homolog (Drosophila) 1.51091
SPRR1B small proline-rich protein 1B 1.4984
ACTN1 actinin, alpha 1 1.49548
ABLIM3 actin binding LIM protein family, member 3 1.49386
MAP2K4 mitogen-activated protein kinase kinase 4 1.49056
SSSCA1 Sjogren syndrome/scleroderma autoantigen 1 1.48733
FOSL1 FOS-like antigen 1 1.48632
SAA1 serum amyloid A1 1.4837
TNFAIP3 tumor necrosis factor, alpha-induced protein 3 1.47648
TRIP4 thyroid hormone receptor interactor 4 1.47218
VOPP1 vesicular, overexpressed in cancer, prosurvival protein 1 1.46913
EFCAB2 EF-hand calcium binding domain 2 1.46538
PLCH2 phospholipase C, eta 2 1.45827
BNC1 basonuclin 1 1.45709
MUS81 MUS81 structure-specific endonuclease subunit 1.44795
SERPINB7 serpin peptidase inhibitor, clade B (ovalbumin), member 7 1.43574
TUBB4B tubulin, beta 4B class IVb 1.43198
HERC3 HECT and RLD domain containing E3 ubiquitin protein ligase 3 1.43052
SERPINE1 serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1 1.43018
KRT35 keratin 35, type I 1.42986
BICD2 bicaudal D homolog 2 (Drosophila) 1.4276
KRT3 keratin 3, type II 1.42512
MRPS22 mitochondrial ribosomal protein S22 1.42328
MPHOSPH6 M-phase phosphoprotein 6 1.4204
CTNNAL1 catenin (cadherin-associated protein), alpha-like 1 1.41999
DPF2 D4, zinc and double PHD fingers family 2 1.41899

low expression

Symbol Name Standardized Value
SLC35C2 solute carrier family 35 (GDP-fucose transporter), member C2 -3.53725
THAP9 THAP domain containing 9 -3.06968
NR4A1 nuclear receptor subfamily 4, group A, member 1 -3.0361
ERP29 endoplasmic reticulum protein 29 -2.82625
CTRC chymotrypsin C (caldecrin) -2.76946
SLC29A2 solute carrier family 29 (equilibrative nucleoside transporter), member 2 -2.7471
SULT1A1 sulfotransferase family, cytosolic, 1A, phenol-preferring, member 1 -2.67827
ASPSCR1 alveolar soft part sarcoma chromosome region, candidate 1 -2.63871
DEAF1 DEAF1 transcription factor -2.53497
ENPP4 ectonucleotide pyrophosphatase/phosphodiesterase 4 (putative) -2.43436
PARP11 poly (ADP-ribose) polymerase family, member 11 -2.4088
CCL8 chemokine (C-C motif) ligand 8 -2.39108
SCAPER S-phase cyclin A-associated protein in the ER -2.37014
KLHDC3 kelch domain containing 3 -2.31859
PDE8B phosphodiesterase 8B -2.31849
PMVK phosphomevalonate kinase -2.27095
BIRC7 baculoviral IAP repeat containing 7 -2.26785
APOM apolipoprotein M -2.26306
AFP alpha-fetoprotein -2.25179
PPOX protoporphyrinogen oxidase -2.19737
FRAT1 frequently rearranged in advanced T-cell lymphomas 1 -2.19122
POFUT1 protein O-fucosyltransferase 1 -2.18795
MAGEF1 melanoma antigen family F1 -2.18526
TMEM8A transmembrane protein 8A -2.15749
CA5BP1 carbonic anhydrase VB pseudogene 1 -2.14256
GP5 glycoprotein V (platelet) -2.13453
SLC4A5 solute carrier family 4 (sodium bicarbonate cotransporter), member 5 -2.12277
IGF1 insulin-like growth factor 1 (somatomedin C) -2.11519
FAM135A family with sequence similarity 135, member A -2.11435
TARBP1 TAR (HIV-1) RNA binding protein 1 -2.11223
RASSF1 Ras association (RalGDS/AF-6) domain family member 1 -2.04532
RPS9 ribosomal protein S9 -2.03311
CBFA2T2 core-binding factor, runt domain, alpha subunit 2; translocated to, 2 -2.03168
VASH1 vasohibin 1 -1.98802
GALK1 galactokinase 1 -1.95111
DGCR9 DiGeorge syndrome critical region gene 9 (non-protein coding) -1.93351
CDC37 cell division cycle 37 -1.93206
UCN urocortin -1.92628
CDK5RAP3 CDK5 regulatory subunit associated protein 3 -1.90391
DTNB dystrobrevin, beta -1.90236
PODXL2 podocalyxin-like 2 -1.88822
POPDC2 popeye domain containing 2 -1.8684
DSTYK dual serine/threonine and tyrosine protein kinase -1.86774
LMO2 LIM domain only 2 (rhombotin-like 1) -1.86282
SETD5 SET domain containing 5 -1.84487
IPW imprinted in Prader-Willi syndrome (non-protein coding) -1.84064
MLLT10 myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 10 -1.83692
NPRL2 nitrogen permease regulator-like 2 (S. cerevisiae) -1.83648
SYF2 SYF2 pre-mRNA-splicing factor -1.83592
MFSD7 major facilitator superfamily domain containing 7 -1.82895
CLUL1 clusterin-like 1 (retinal) -1.82635
ZNF665 zinc finger protein 665 -1.82523
DDB1 damage-specific DNA binding protein 1, 127kDa -1.82364
FAM8A1 family with sequence similarity 8, member A1 -1.81895
RHBDL1 rhomboid, veinlet-like 1 (Drosophila) -1.81201
ZNF692 zinc finger protein 692 -1.80824
SYT13 synaptotagmin XIII -1.78798
PLA2G6 phospholipase A2, group VI (cytosolic, calcium-independent) -1.77624
ZNF749 zinc finger protein 749 -1.77488
OXNAD1 oxidoreductase NAD-binding domain containing 1 -1.76931
ADCY6 adenylate cyclase 6 -1.76585
SUV420H1 suppressor of variegation 4-20 homolog 1 (Drosophila) -1.76114
TAF6L TAF6-like RNA polymerase II, p300/CBP-associated factor (PCAF)-associated factor, 65kDa -1.75552
TMEM115 transmembrane protein 115 -1.72922
GAB1 GRB2-associated binding protein 1 -1.72822
LONP1 lon peptidase 1, mitochondrial -1.72678
IDH3G isocitrate dehydrogenase 3 (NAD+) gamma -1.70756
MAN2A2 mannosidase, alpha, class 2A, member 2 -1.69965
GRIN2C glutamate receptor, ionotropic, N-methyl D-aspartate 2C -1.69768
TRAPPC6A trafficking protein particle complex 6A -1.69526
KCNIP2 Kv channel interacting protein 2 -1.69057
TSFM Ts translation elongation factor, mitochondrial -1.68212
SUZ12P1 suppressor of zeste 12 homolog pseudogene 1 -1.67862
SMAP1 small ArfGAP 1 -1.67854
CRAT carnitine O-acetyltransferase -1.67767
SSR4 signal sequence receptor, delta -1.67563
WAS Wiskott-Aldrich syndrome -1.66285
PGD phosphogluconate dehydrogenase -1.65566
CLN3 ceroid-lipofuscinosis, neuronal 3 -1.65359
UGT2A1 UDP glucuronosyltransferase 2 family, polypeptide A1, complex locus -1.65096
MSR1 macrophage scavenger receptor 1 -1.63605
GUCY1A2 guanylate cyclase 1, soluble, alpha 2 -1.63474
FOXL1 forkhead box L1 -1.61532
FIG4 FIG4 phosphoinositide 5-phosphatase -1.61465
KLHL41 kelch-like family member 41 -1.61015
CCDC22 coiled-coil domain containing 22 -1.60047
NCR1 natural cytotoxicity triggering receptor 1 -1.58112
COX7A2L cytochrome c oxidase subunit VIIa polypeptide 2 like -1.57833
ADCK3 aarF domain containing kinase 3 -1.5754
RAB11FIP3 RAB11 family interacting protein 3 (class II) -1.57478
CST8 cystatin 8 (cystatin-related epididymal specific) -1.57262
LOC145678 uncharacterized LOC145678 -1.57253
KIT v-kit Hardy-Zuckerman 4 feline sarcoma viral oncogene homolog -1.57227
POGZ pogo transposable element with ZNF domain -1.56777
FNTB farnesyltransferase, CAAX box, beta -1.56767
EPHA3 EPH receptor A3 -1.56555
EGFL6 EGF-like-domain, multiple 6 -1.56496
AES amino-terminal enhancer of split -1.55732
KCNMB4 potassium channel subfamily M regulatory beta subunit 4 -1.5572
CILP cartilage intermediate layer protein, nucleotide pyrophosphohydrolase -1.55573
TTC13 tetratricopeptide repeat domain 13 -1.55244
UROS uroporphyrinogen III synthase -1.54371
MVD mevalonate (diphospho) decarboxylase -1.53894
N4BP2L2 NEDD4 binding protein 2-like 2 -1.53724
ACVRL1 activin A receptor type II-like 1 -1.53579
ZNF3 zinc finger protein 3 -1.53433
RPL3L ribosomal protein L3-like -1.51895
ILVBL ilvB (bacterial acetolactate synthase)-like -1.51851
IKZF4 IKAROS family zinc finger 4 (Eos) -1.51022
KDR kinase insert domain receptor -1.51012
AKAP8L A kinase (PRKA) anchor protein 8-like -1.50933
NFKBIL1 nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor-like 1 -1.50349
IQGAP2 IQ motif containing GTPase activating protein 2 -1.50285
CAPN11 calpain 11 -1.49551
SLC11A1 solute carrier family 11 (proton-coupled divalent metal ion transporter), member 1 -1.49343
ANGPT2 angiopoietin 2 -1.49133
ICOSLG inducible T-cell co-stimulator ligand -1.48841
LRRTM4 leucine rich repeat transmembrane neuronal 4 -1.48518
YPEL1 yippee-like 1 (Drosophila) -1.48507
DHX38 DEAH (Asp-Glu-Ala-His) box polypeptide 38 -1.48466
CHL1 cell adhesion molecule L1-like -1.48319
ELF2 E74-like factor 2 (ets domain transcription factor) -1.48027
SLC17A2 solute carrier family 17, member 2 -1.47973
MAGEA6 melanoma antigen family A6 -1.47512
CPS1 carbamoyl-phosphate synthase 1, mitochondrial -1.47082
CLK2 CDC-like kinase 2 -1.47073
RANBP9 RAN binding protein 9 -1.46903
GAD2 glutamate decarboxylase 2 (pancreatic islets and brain, 65kDa) -1.46092
AKR7A3 aldo-keto reductase family 7, member A3 (aflatoxin aldehyde reductase) -1.4597
NCR3 natural cytotoxicity triggering receptor 3 -1.44447
DPYSL4 dihydropyrimidinase-like 4 -1.44232
NUDT7 nudix (nucleoside diphosphate linked moiety X)-type motif 7 -1.44117
HAGH hydroxyacylglutathione hydrolase -1.43926
BSG basigin (Ok blood group) -1.4375
SCD stearoyl-CoA desaturase (delta-9-desaturase) -1.43729
HOXD1 homeobox D1 -1.43671
FGF17 fibroblast growth factor 17 -1.43521
QPRT quinolinate phosphoribosyltransferase -1.43323
POLL polymerase (DNA directed), lambda -1.43081
SCAND1 SCAN domain containing 1 -1.42641
ROBO1 roundabout, axon guidance receptor, homolog 1 (Drosophila) -1.42567
APEH acylaminoacyl-peptide hydrolase -1.42517