SCC-25 Gene Set

Dataset COSMIC Cell Line Gene CNV Profiles
Category genomics
Type cell line
Description Human squamous cell carcinoma cell line; established from the biopsy of a squamous cell carcinoma of the tongue of a 70-year-old man. (BRENDA Tissue and Enzyme Source Ontology, BTO_0003774)
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Genes

121 genes with high or low copy number in SCC-25 relative to other cell lines from the COSMIC Cell Line Gene CNV Profiles dataset.

high copy number

Symbol Name Standardized Value
COA4 cytochrome c oxidase assembly factor 4 homolog (S. cerevisiae) 2.49065
PLEKHB1 pleckstrin homology domain containing, family B (evectins) member 1 2.49065
MRPL48 mitochondrial ribosomal protein L48 2.49065
RAB6A RAB6A, member RAS oncogene family 2.49065
PAAF1 proteasomal ATPase-associated factor 1 2.49065
DNAJB13 DnaJ (Hsp40) homolog, subfamily B, member 13 2.44392
UCP2 uncoupling protein 2 (mitochondrial, proton carrier) 2.44392
RELT RELT tumor necrosis factor receptor 2.44392
FAM168A family with sequence similarity 168, member A 2.44392
UCP3 uncoupling protein 3 (mitochondrial, proton carrier) 2.44392
MIR4692 microRNA 4692 2.41451
STARD10 StAR-related lipid transfer (START) domain containing 10 2.41451
ARHGEF17 Rho guanine nucleotide exchange factor (GEF) 17 2.41451
P2RY2 purinergic receptor P2Y, G-protein coupled, 2 2.41451
ATG16L2 autophagy related 16-like 2 (S. cerevisiae) 2.41451
P2RY6 pyrimidinergic receptor P2Y, G-protein coupled, 6 2.41451
PDE2A phosphodiesterase 2A, cGMP-stimulated 2.41451
ARAP1 ArfGAP with RhoGAP domain, ankyrin repeat and PH domain 1 2.41451
MIR139 microRNA 139 2.41451
PHOX2A paired-like homeobox 2a 2.39327
FCHSD2 FCH and double SH3 domains 2 2.39327
INPPL1 inositol polyphosphate phosphatase-like 1 2.39327
CLPB ClpB homolog, mitochondrial AAA ATPase chaperonin 2.36889
FOLR2 folate receptor 2 (fetal) 2.36889
FOLR3 folate receptor 3 (gamma) 2.36889
ALG1L9P asparagine-linked glycosylation 1-like 9, pseudogene 2.36889
FOLR1 folate receptor 1 (adult) 2.36889
DEFB108B defensin, beta 108B 2.36889
FAM86C1 family with sequence similarity 86, member C1 2.36889
LAMTOR1 late endosomal/lysosomal adaptor, MAPK and MTOR activator 1 2.35236
ANAPC15 anaphase promoting complex subunit 15 2.35236
LRTOMT leucine rich transmembrane and O-methyltransferase domain containing 2.3178
LOC100133315 transient receptor potential cation channel, subfamily C, member 2-like 2.3178
RNF121 ring finger protein 121 2.3178
IL18BP interleukin 18 binding protein 2.3178
NUMA1 nuclear mitotic apparatus protein 1 2.3178
MIR3165 microRNA 3165 2.3178
LOC100129216 beta-defensin 131-like 2.3178
KRTAP5-9 keratin associated protein 5-9 2.26395
KRTAP5-8 keratin associated protein 5-8 2.26395
KRTAP5-7 keratin associated protein 5-7 2.26395
KRTAP5-11 keratin associated protein 5-11 2.26395
KRTAP5-10 keratin associated protein 5-10 2.25904
NADSYN1 NAD synthetase 1 2.25904
FLJ42102 uncharacterized LOC399923 2.24845
DHCR7 7-dehydrocholesterol reductase 2.24845
MRGPRD MAS-related GPR, member D 2.22783
MRGPRF MAS-related GPR, member F 2.22633
MIR3664 microRNA 3664 2.22291
SHANK2-AS3 SHANK2 antisense RNA 3 2.22291
TPCN2 two pore segment channel 2 2.21258
FADD Fas (TNFRSF6)-associated via death domain 2.16564
MIR548K microRNA 548k 2.16564
PPFIA1 protein tyrosine phosphatase, receptor type, f polypeptide (PTPRF), interacting protein (liprin), alpha 1 2.16459
MYEOV myeloma overexpressed 2.16459
ANO1 anoctamin 1, calcium activated chloride channel 2.16307
FGF3 fibroblast growth factor 3 2.16307
CTTN cortactin 2.16307
FGF4 fibroblast growth factor 4 2.16176
CCND1 cyclin D1 2.1605
FGF19 fibroblast growth factor 19 2.1605
ORAOV1 oral cancer overexpressed 1 2.16017
OR11H2 olfactory receptor, family 11, subfamily H, member 2 2.09073
C2CD3 C2 calcium-dependent domain containing 3 2.08712
OR4M1 olfactory receptor, family 4, subfamily M, member 1 2.06989
OR4Q3 olfactory receptor, family 4, subfamily Q, member 3 2.06989
OR4K2 olfactory receptor, family 4, subfamily K, member 2 2.06626
OR4K5 olfactory receptor, family 4, subfamily K, member 5 2.06626
OR4K1 olfactory receptor, family 4, subfamily K, member 1 2.06626
OR4N2 olfactory receptor, family 4, subfamily N, member 2 2.06626
SHANK2-AS1 SHANK2 antisense RNA 1 2.05422
SHANK2 SH3 and multiple ankyrin repeat domains 2 2.04969

low copy number

Symbol Name Standardized Value
SORBS2 sorbin and SH3 domain containing 2 -3.83684
FAM71C family with sequence similarity 71, member C -3.83684
FRG1 FSHD region gene 1 -3.83684
FLJ38576 uncharacterized LOC651430 -3.83684
KLKB1 kallikrein B, plasma (Fletcher factor) 1 -3.83684
TLR3 toll-like receptor 3 -3.83684
CYP4V2 cytochrome P450, family 4, subfamily V, polypeptide 2 -3.83684
FAM149A family with sequence similarity 149, member A -3.83684
DUX4L6 double homeobox 4 like 6 -3.83684
DUX4L4 double homeobox 4 like 4 -3.83684
DUX4L5 double homeobox 4 like 5 -3.83684
TFF3 trefoil factor 3 (intestinal) -3.7119
FAM3B family with sequence similarity 3, member B -3.7119
F11 coagulation factor XI -3.7119
MX2 MX dynamin-like GTPase 2 -3.7119
TMPRSS2 transmembrane protease, serine 2 -3.61078
RIPK4 receptor-interacting serine-threonine kinase 4 -3.61078
LINC00112 long intergenic non-protein coding RNA 112 -3.61078
LINC00111 long intergenic non-protein coding RNA 111 -3.61078
UMODL1-AS1 UMODL1 antisense RNA 1 -3.61078
ZNF295-AS1 ZNF295 antisense RNA 1 -3.61078
ZBTB21 zinc finger and BTB domain containing 21 -3.61078
C2CD2 C2 calcium-dependent domain containing 2 -3.61078
ABCG1 ATP-binding cassette, sub-family G (WHITE), member 1 -3.61078
MX1 MX dynamin-like GTPase 1 -3.61078
TRIML2 tripartite motif family-like 2 -3.61078
PRDM15 PR domain containing 15 -3.61078
UMODL1 uromodulin-like 1 -3.61078
TRIML1 tripartite motif family-like 1 -3.61078
LOC339975 uncharacterized LOC339975 -3.61078
ZFP42 ZFP42 zinc finger protein -3.61078
LINC00479 long intergenic non-protein coding RNA 479 -3.61078
MTNR1A melatonin receptor 1A -3.57558
FAT1 FAT atypical cadherin 1 -3.53061
DUX4 double homeobox 4 -3.17697
FHIT fragile histidine triad -3.12964
MIR4760 microRNA 4760 -3.11641
DSCAM-AS1 DSCAM antisense RNA 1 -3.11641
DSCAM Down syndrome cell adhesion molecule -3.11641
MIR3197 microRNA 3197 -3.11641
DSCAM-IT1 DSCAM intronic transcript 1 -3.11641
PLAC4 placenta-specific 4 -3.11641
LINC00323 long intergenic non-protein coding RNA 323 -3.11641
BACE2 beta-site APP-cleaving enzyme 2 -3.05196
FAM90A25P family with sequence similarity 90, member A7 pseudogene -3.03592
DEFB109P1 defensin, beta 109, pseudogene 1 -2.93929
ZNF705A zinc finger protein 705A -2.84373
FAM66A family with sequence similarity 66, member A -2.82872
LOC649352 ubiquitin carboxyl-terminal hydrolase 17-like protein 2-like -2.80262