SCC-4 Gene Set

Dataset COSMIC Cell Line Gene CNV Profiles
Category genomics
Type cell line
Description Human squamous cell carcinoma cell line; established from the squamous cell carcinoma of the tongue from a 55-year-old man after radio- and chemotherapy in 1980. (BRENDA Tissue and Enzyme Source Ontology, BTO_0003775)
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Genes

51 genes with high or low copy number in SCC-4 relative to other cell lines from the COSMIC Cell Line Gene CNV Profiles dataset.

high copy number

Symbol Name Standardized Value
TMEM243 transmembrane protein 243, mitochondrial 2.41451
DMTF1 cyclin D binding myb-like transcription factor 1 2.41451
TP53TG1 TP53 target 1 (non-protein coding) 2.41451
ABCB4 ATP-binding cassette, sub-family B (MDR/TAP), member 4 2.39327
CROT carnitine O-octanoyltransferase 2.39327
C7ORF62 chromosome 7 open reading frame 62 2.39327
KIAA1324L KIAA1324-like 2.39327
ZNF804B zinc finger protein 804B 2.39327
DBF4 DBF4 zinc finger 2.36889
RUNDC3B RUN domain containing 3B 2.36889
SLC25A40 solute carrier family 25, member 40 2.36889
GRM3 glutamate receptor, metabotropic 3 2.36889
ABCB1 ATP-binding cassette, sub-family B (MDR/TAP), member 1 2.36889
SRI sorcin 2.35236
STEAP4 STEAP family member 4 2.35236
ADAM22 ADAM metallopeptidase domain 22 2.30944
SNORA67 small nucleolar RNA, H/ACA box 67 2.283
MIR548K microRNA 548k 2.16564
FADD Fas (TNFRSF6)-associated via death domain 2.16564
PPFIA1 protein tyrosine phosphatase, receptor type, f polypeptide (PTPRF), interacting protein (liprin), alpha 1 2.16459
ANO1 anoctamin 1, calcium activated chloride channel 2.16307
FGF3 fibroblast growth factor 3 2.16307
CTTN cortactin 2.16307
FGF4 fibroblast growth factor 4 2.16176
CCND1 cyclin D1 2.1605
FGF19 fibroblast growth factor 19 2.1605
ORAOV1 oral cancer overexpressed 1 2.16017
SEMA3D sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3D 2.08021
SHANK2-AS1 SHANK2 antisense RNA 1 2.05422
SHANK2 SH3 and multiple ankyrin repeat domains 2 2.04969

low copy number

Symbol Name Standardized Value
AASS aminoadipate-semialdehyde synthase -3.39516
GRM8 glutamate receptor, metabotropic 8 -3.38669
AA06 uncharacterized LOC100506677 -3.2703
TMLHE trimethyllysine hydroxylase, epsilon -3.2703
TMLHE-AS1 TMLHE antisense RNA 1 -3.2703
CCL8 chemokine (C-C motif) ligand 8 -3.24687
TMEM98 transmembrane protein 98 -3.24687
CCL11 chemokine (C-C motif) ligand 11 -3.24687
ASIC2 acid sensing (proton gated) ion channel 2 -3.24687
CCL7 chemokine (C-C motif) ligand 7 -3.24687
CCL1 chemokine (C-C motif) ligand 1 -3.24687
CCL13 chemokine (C-C motif) ligand 13 -3.24687
SPACA3 sperm acrosome associated 3 -3.24687
CCL2 chemokine (C-C motif) ligand 2 -3.24687
VAMP7 vesicle-associated membrane protein 7 -3.14331
SPRY3 sprouty homolog 3 (Drosophila) -3.14331
F8A1 coagulation factor VIII-associated 1 -3.12964
MIR1184-3 microRNA 1184-3 -3.12964
H2AFB3 H2A histone family, member B3 -3.12964
ALG1L2 ALG1, chitobiosyldiphosphodolichol beta-mannosyltransferase-like 2 -2.73329
BTNL3 butyrophilin-like 3 -2.72661