SCC-4 Gene Set

Dataset COSMIC Cell Line Gene Mutation Profiles
Category genomics
Type cell line
Description Human squamous cell carcinoma cell line; established from the squamous cell carcinoma of the tongue from a 55-year-old man after radio- and chemotherapy in 1980. (BRENDA Tissue and Enzyme Source Ontology, BTO_0003775)
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Genes

341 genes mutated in the SCC-4 cell line from the COSMIC Cell Line Gene Mutation Profiles dataset.

Symbol Name
AARSD1 alanyl-tRNA synthetase domain containing 1
ABCA12 ATP-binding cassette, sub-family A (ABC1), member 12
ABCA2 ATP-binding cassette, sub-family A (ABC1), member 2
ABHD12 abhydrolase domain containing 12
ABHD17C abhydrolase domain containing 17C
ABI3BP ABI family, member 3 (NESH) binding protein
ACAP2 ArfGAP with coiled-coil, ankyrin repeat and PH domains 2
ACOT13 acyl-CoA thioesterase 13
ACSS3 acyl-CoA synthetase short-chain family member 3
ADAMTS17 ADAM metallopeptidase with thrombospondin type 1 motif, 17
ADAMTSL4 ADAMTS-like 4
ADGRL1 adhesion G protein-coupled receptor L1
AHNAK2 AHNAK nucleoprotein 2
AHR aryl hydrocarbon receptor
AIF1 allograft inflammatory factor 1
ALS2CL ALS2 C-terminal like
AMPD1 adenosine monophosphate deaminase 1
AMPD2 adenosine monophosphate deaminase 2
ANAPC1 anaphase promoting complex subunit 1
ANGPTL5 angiopoietin-like 5
ANKRD36 ankyrin repeat domain 36
ANKRD6 ankyrin repeat domain 6
ANKS1A ankyrin repeat and sterile alpha motif domain containing 1A
ANO6 anoctamin 6
ARHGAP4 Rho GTPase activating protein 4
ARHGAP8 Rho GTPase activating protein 8
ARHGEF11 Rho guanine nucleotide exchange factor (GEF) 11
ARHGEF38 Rho guanine nucleotide exchange factor (GEF) 38
ARNTL2 aryl hydrocarbon receptor nuclear translocator-like 2
ARSI arylsulfatase family, member I
ASPM asp (abnormal spindle) homolog, microcephaly associated (Drosophila)
ATP2C1 ATPase, Ca++ transporting, type 2C, member 1
ATP6V0A2 ATPase, H+ transporting, lysosomal V0 subunit a2
ATXN7 ataxin 7
B3GNT7 UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 7
BAG5 BCL2-associated athanogene 5
BCLAF1 BCL2-associated transcription factor 1
BEND5 BEN domain containing 5
BIRC6 baculoviral IAP repeat containing 6
BZRAP1 benzodiazepine receptor (peripheral) associated protein 1
C6 complement component 6
CABYR calcium binding tyrosine-(Y)-phosphorylation regulated
CALCRL calcitonin receptor-like
CARD6 caspase recruitment domain family, member 6
CASC5 cancer susceptibility candidate 5
CCDC114 coiled-coil domain containing 114
CCDC13 coiled-coil domain containing 13
CCR10 chemokine (C-C motif) receptor 10
CD226 CD226 molecule
CD320 CD320 molecule
CD40LG CD40 ligand
CDAN1 codanin 1
CDC123 cell division cycle 123
CDH19 cadherin 19, type 2
CDH20 cadherin 20, type 2
CDHR2 cadherin-related family member 2
CDK14 cyclin-dependent kinase 14
CDKN2A cyclin-dependent kinase inhibitor 2A
CDON cell adhesion associated, oncogene regulated
CENPF centromere protein F, 350/400kDa
CGN cingulin
CHD4 chromodomain helicase DNA binding protein 4
CHRAC1 chromatin accessibility complex 1
CHRNA9 cholinergic receptor, nicotinic, alpha 9 (neuronal)
CLCA4 chloride channel accessory 4
CLSPN claspin
CLSTN2 calsyntenin 2
CNTF ciliary neurotrophic factor
CORO7 coronin 7
CPT1A carnitine palmitoyltransferase 1A (liver)
CR2 complement component (3d/Epstein Barr virus) receptor 2
CSMD2 CUB and Sushi multiple domains 2
CSRP2BP CSRP2 binding protein
CTSW cathepsin W
CYP4F8 cytochrome P450, family 4, subfamily F, polypeptide 8
DCAF12L1 DDB1 and CUL4 associated factor 12-like 1
DCC DCC netrin 1 receptor
DDX28 DEAD (Asp-Glu-Ala-Asp) box polypeptide 28
DNAH11 dynein, axonemal, heavy chain 11
DNAH14 dynein, axonemal, heavy chain 14
DNAH7 dynein, axonemal, heavy chain 7
DNAJB5 DnaJ (Hsp40) homolog, subfamily B, member 5
DNHD1 dynein heavy chain domain 1
DNTTIP2 deoxynucleotidyltransferase, terminal, interacting protein 2
EIF2D eukaryotic translation initiation factor 2D
EPG5 ectopic P-granules autophagy protein 5 homolog (C. elegans)
EPHA2 EPH receptor A2
EPHB3 EPH receptor B3
EPO erythropoietin
ESRP2 epithelial splicing regulatory protein 2
ESYT1 extended synaptotagmin-like protein 1
F11 coagulation factor XI
FAM214A family with sequence similarity 214, member A
FAM92A1 family with sequence similarity 92, member A1
FARP2 FERM, RhoGEF and pleckstrin domain protein 2
FASLG Fas ligand (TNF superfamily, member 6)
FBXO18 F-box protein, helicase, 18
FBXO30 F-box protein 30
FCGBP Fc fragment of IgG binding protein
FLG filaggrin
FMN2 formin 2
FMOD fibromodulin
FOXB2 forkhead box B2
FRG2C FSHD region gene 2 family, member C
FSCB fibrous sheath CABYR binding protein
FTH1P19 ferritin, heavy polypeptide 1 pseudogene 19
FUT6 fucosyltransferase 6 (alpha (1,3) fucosyltransferase)
GATA6 GATA binding protein 6
GEMIN4 gem (nuclear organelle) associated protein 4
GJB6 gap junction protein, beta 6, 30kDa
GMPPA GDP-mannose pyrophosphorylase A
GPATCH4 G patch domain containing 4
GRB7 growth factor receptor-bound protein 7
GRK5 G protein-coupled receptor kinase 5
GRM5 glutamate receptor, metabotropic 5
GYLTL1B glycosyltransferase-like 1B
HECW2 HECT, C2 and WW domain containing E3 ubiquitin protein ligase 2
HEPACAM2 HEPACAM family member 2
HHLA2 HERV-H LTR-associating 2
HLA-B major histocompatibility complex, class I, B
HLA-C major histocompatibility complex, class I, C
HMCN1 hemicentin 1
HNRNPM heterogeneous nuclear ribonucleoprotein M
HOXD4 homeobox D4
HPSE2 heparanase 2 (inactive)
HSPA14 heat shock 70kDa protein 14
HTR3E 5-hydroxytryptamine (serotonin) receptor 3E, ionotropic
IDE insulin-degrading enzyme
IGSF3 immunoglobulin superfamily, member 3
IL36A interleukin 36, alpha
INO80 INO80 complex subunit
INPP5J inositol polyphosphate-5-phosphatase J
INPPL1 inositol polyphosphate phosphatase-like 1
IQGAP1 IQ motif containing GTPase activating protein 1
IQGAP3 IQ motif containing GTPase activating protein 3
ITGB1 integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12)
JAKMIP1 janus kinase and microtubule interacting protein 1
KAT6B K(lysine) acetyltransferase 6B
KDM3A lysine (K)-specific demethylase 3A
KHNYN KH and NYN domain containing
KIAA1109 KIAA1109
KIAA1549 KIAA1549
KIF1A kinesin family member 1A
KIF6 kinesin family member 6
KIR2DL1 killer cell immunoglobulin-like receptor, two domains, long cytoplasmic tail, 1
KIR2DL3 killer cell immunoglobulin-like receptor, two domains, long cytoplasmic tail, 3
KLHL1 kelch-like family member 1
KLHL2 kelch-like family member 2
KLRC3 killer cell lectin-like receptor subfamily C, member 3
KMT2D lysine (K)-specific methyltransferase 2D
KRTAP10-12 keratin associated protein 10-12
KRTAP4-3 keratin associated protein 4-3
KRTAP5-7 keratin associated protein 5-7
LAMC1 laminin, gamma 1 (formerly LAMB2)
LCN12 lipocalin 12
LILRA2 leukocyte immunoglobulin-like receptor, subfamily A (with TM domain), member 2
LMNA lamin A/C
LNPEP leucyl/cystinyl aminopeptidase
LOC390956 peptidyl-prolyl cis-trans isomerase A pseudogene
LONP1 lon peptidase 1, mitochondrial
LRIT3 leucine-rich repeat, immunoglobulin-like and transmembrane domains 3
LRP1B low density lipoprotein receptor-related protein 1B
LRRK2 leucine-rich repeat kinase 2
LY75 lymphocyte antigen 75
LYST lysosomal trafficking regulator
LYZL1 lysozyme-like 1
MAGEB16 melanoma antigen family B16
MAN2B2 mannosidase, alpha, class 2B, member 2
MAP7D3 MAP7 domain containing 3
MAPK15 mitogen-activated protein kinase 15
MCM5 minichromosome maintenance complex component 5
MDGA2 MAM domain containing glycosylphosphatidylinositol anchor 2
MEIS1 Meis homeobox 1
METTL11B methyltransferase like 11B
MICALCL MICAL C-terminal like
MPP4 membrane protein, palmitoylated 4 (MAGUK p55 subfamily member 4)
MRPL54 mitochondrial ribosomal protein L54
MUC16 mucin 16, cell surface associated
MUC17 mucin 17, cell surface associated
MUC20 mucin 20, cell surface associated
MUC4 mucin 4, cell surface associated
MYF5 myogenic factor 5
MYH7 myosin, heavy chain 7, cardiac muscle, beta
MYLK myosin light chain kinase
MYO7A myosin VIIA
MYO7B myosin VIIB
MYPN myopalladin
NAP1L4 nucleosome assembly protein 1-like 4
NCAPH non-SMC condensin I complex, subunit H
NF1 neurofibromin 1
NFIB nuclear factor I/B
NIF3L1 NIF3 NGG1 interacting factor 3-like 1 (S. cerevisiae)
NINL ninein-like
NLRP4 NLR family, pyrin domain containing 4
NPAS4 neuronal PAS domain protein 4
NPSR1 neuropeptide S receptor 1
NSD1 nuclear receptor binding SET domain protein 1
OIT3 oncoprotein induced transcript 3
OMA1 OMA1 zinc metallopeptidase
OR10G4 olfactory receptor, family 10, subfamily G, member 4
OR51A2 olfactory receptor, family 51, subfamily A, member 2
OR51A7 olfactory receptor, family 51, subfamily A, member 7
OR51I1 olfactory receptor, family 51, subfamily I, member 1
OR52A1 olfactory receptor, family 52, subfamily A, member 1
OR5AK2 olfactory receptor, family 5, subfamily AK, member 2
OR6C6 olfactory receptor, family 6, subfamily C, member 6
OTOF otoferlin
OTOP1 otopetrin 1
P4HA1 prolyl 4-hydroxylase, alpha polypeptide I
PAQR9 progestin and adipoQ receptor family member IX
PARP12 poly (ADP-ribose) polymerase family, member 12
PARP6 poly (ADP-ribose) polymerase family, member 6
PCDH12 protocadherin 12
PCDHA13 protocadherin alpha 13
PCM1 pericentriolar material 1
PCYT2 phosphate cytidylyltransferase 2, ethanolamine
PDE1C phosphodiesterase 1C, calmodulin-dependent 70kDa
PDE4DIP phosphodiesterase 4D interacting protein
PDGFRL platelet-derived growth factor receptor-like
PDHA2 pyruvate dehydrogenase (lipoamide) alpha 2
PER3 period circadian clock 3
PEX11B peroxisomal biogenesis factor 11 beta
PHRF1 PHD and ring finger domains 1
PICK1 protein interacting with PRKCA 1
PIEZO1 piezo-type mechanosensitive ion channel component 1
PIEZO2 piezo-type mechanosensitive ion channel component 2
PIK3C2A phosphatidylinositol-4-phosphate 3-kinase, catalytic subunit type 2 alpha
PLA2G4F phospholipase A2, group IVF
PLD1 phospholipase D1, phosphatidylcholine-specific
PNMA2 paraneoplastic Ma antigen 2
PNMAL2 paraneoplastic Ma antigen family-like 2
PNN pinin, desmosome associated protein
POLI polymerase (DNA directed) iota
POM121L12 POM121 transmembrane nucleoporin-like 12
POTEF POTE ankyrin domain family, member F
POTEJ POTE ankyrin domain family, member J
PPP4R1 protein phosphatase 4, regulatory subunit 1
PRKAA1 protein kinase, AMP-activated, alpha 1 catalytic subunit
PRR5-ARHGAP8 PRR5-ARHGAP8 readthrough
PTCHD2 patched domain containing 2
PTCHD4 patched domain containing 4
PTGES3L-AARSD1 PTGES3L-AARSD1 readthrough
PTPN12 protein tyrosine phosphatase, non-receptor type 12
RABEP1 rabaptin, RAB GTPase binding effector protein 1
RABL6 RAB, member RAS oncogene family-like 6
RALB v-ral simian leukemia viral oncogene homolog B
RALGDS ral guanine nucleotide dissociation stimulator
RANBP6 RAN binding protein 6
RBCK1 RanBP-type and C3HC4-type zinc finger containing 1
RBM28 RNA binding motif protein 28
RBMXL3 RNA binding motif protein, X-linked-like 3
RC3H1 ring finger and CCCH-type domains 1
RCC2 regulator of chromosome condensation 2
RFC4 replication factor C (activator 1) 4, 37kDa
RHOT2 ras homolog family member T2
RPIA ribose 5-phosphate isomerase A
RPS3 ribosomal protein S3
RUFY4 RUN and FYVE domain containing 4
RYR1 ryanodine receptor 1 (skeletal)
RYR3 ryanodine receptor 3
SACK1G scaffolding CK1 anchoring protein G
SCN2A sodium channel, voltage gated, type II alpha subunit
SCUBE1 signal peptide, CUB domain, EGF-like 1
SEC24C SEC24 family member C
SEMG1 semenogelin I
SETD6 SET domain containing 6
SFTPD surfactant protein D
SGPL1 sphingosine-1-phosphate lyase 1
SIRT1 sirtuin 1
SLC17A7 solute carrier family 17 (vesicular glutamate transporter), member 7
SLC17A9 solute carrier family 17 (vesicular nucleotide transporter), member 9
SLC22A16 solute carrier family 22 (organic cation/carnitine transporter), member 16
SLC28A1 solute carrier family 28 (concentrative nucleoside transporter), member 1
SLC7A8 solute carrier family 7 (amino acid transporter light chain, L system), member 8
SLCO1C1 solute carrier organic anion transporter family, member 1C1
SLITRK3 SLIT and NTRK-like family, member 3
SMARCA5 SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 5
SMG5 SMG5 nonsense mediated mRNA decay factor
SNTG2 syntrophin, gamma 2
SPANXD SPANX family, member D
SPARCL1 SPARC-like 1 (hevin)
SPTBN2 spectrin, beta, non-erythrocytic 2
SSTR3 somatostatin receptor 3
STAG2 stromal antigen 2
STAT2 signal transducer and activator of transcription 2, 113kDa
STK17B serine/threonine kinase 17b
SVEP1 sushi, von Willebrand factor type A, EGF and pentraxin domain containing 1
SYTL4 synaptotagmin-like 4
TAS2R16 taste receptor, type 2, member 16
TBCE tubulin folding cofactor E
TBX15 T-box 15
TEKT3 tektin 3
THNSL2 threonine synthase-like 2 (S. cerevisiae)
TLR3 toll-like receptor 3
TMC4 transmembrane channel-like 4
TMEM150A transmembrane protein 150A
TMEM177 transmembrane protein 177
TMEM95 transmembrane protein 95
TMPRSS11A transmembrane protease, serine 11A
TMPRSS7 transmembrane protease, serine 7
TNNI3K TNNI3 interacting kinase
TOLLIP toll interacting protein
TP53 tumor protein p53
TRIP11 thyroid hormone receptor interactor 11
TRRAP transformation/transcription domain-associated protein
TRUB1 TruB pseudouridine (psi) synthase family member 1
TSPAN3 tetraspanin 3
TTC21B tetratricopeptide repeat domain 21B
TTN titin
U2AF2 U2 small nuclear RNA auxiliary factor 2
UAP1 UDP-N-acetylglucosamine pyrophosphorylase 1
UBE3A ubiquitin protein ligase E3A
UNC45B unc-45 homolog B (C. elegans)
USP7 ubiquitin specific peptidase 7 (herpes virus-associated)
VCAN versican
VN1R1 vomeronasal 1 receptor 1
VPS45 vacuolar protein sorting 45 homolog (S. cerevisiae)
VWDE von Willebrand factor D and EGF domains
WDR12 WD repeat domain 12
WDR87 WD repeat domain 87
WFS1 Wolfram syndrome 1 (wolframin)
WIPF1 WAS/WASL interacting protein family, member 1
XIRP2 xin actin binding repeat containing 2
YBX1 Y box binding protein 1
YEATS2 YEATS domain containing 2
YIPF7 Yip1 domain family, member 7
YTHDC2 YTH domain containing 2
ZDHHC7 zinc finger, DHHC-type containing 7
ZIC4 Zic family member 4
ZMYND10 zinc finger, MYND-type containing 10
ZNF283 zinc finger protein 283
ZNF335 zinc finger protein 335
ZNF483 zinc finger protein 483
ZNF516 zinc finger protein 516
ZNF622 zinc finger protein 622
ZNF646 zinc finger protein 646
ZNF689 zinc finger protein 689
ZNF766 zinc finger protein 766
ZNF878 zinc finger protein 878
ZSCAN1 zinc finger and SCAN domain containing 1
ZSCAN5B zinc finger and SCAN domain containing 5B