SCF-dependent proteasomal ubiquitin-dependent protein catabolic process Gene Set

Dataset GO Biological Process Annotations 2025
Category structural or functional annotations
Type biological process
Description The chemical reactions and pathways resulting in the breakdown of a protein or peptide by hydrolysis of its peptide bonds, initiated by the covalent attachment of ubiquitin, with ubiquitin-protein ligation catalyzed by an SCF (Skp1/Cul1/F-box protein) complex, and mediated by the proteasome. (Gene Ontology, GO_0031146)
External Link http://amigo.geneontology.org/amigo/term/GO:0031146
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Genes

40 genes participating in the SCF-dependent proteasomal ubiquitin-dependent protein catabolic process biological process from the curated GO Biological Process Annotations 2025 dataset.

Symbol Name
AMN1 antagonist of mitotic exit network 1 homolog (S. cerevisiae)
BTRC beta-transducin repeat containing E3 ubiquitin protein ligase
CCNF cyclin F
CUL1 cullin 1
CUL2 cullin 2
CUL5 cullin 5
DMAC2 distal membrane arm assembly component 2
FBXL13 F-box and leucine-rich repeat protein 13
FBXL14 F-box and leucine-rich repeat protein 14
FBXL15 F-box and leucine-rich repeat protein 15
FBXL16 F-box and leucine-rich repeat protein 16
FBXL17 F-box and leucine-rich repeat protein 17
FBXL2 F-box and leucine-rich repeat protein 2
FBXL20 F-box and leucine-rich repeat protein 20
FBXL3 F-box and leucine-rich repeat protein 3
FBXL4 F-box and leucine-rich repeat protein 4
FBXL5 F-box and leucine-rich repeat protein 5
FBXL6 F-box and leucine-rich repeat protein 6
FBXL7 F-box and leucine-rich repeat protein 7
FBXO17 F-box protein 17
FBXO2 F-box protein 2
FBXO27 F-box protein 27
FBXO3 F-box protein 3
FBXO31 F-box protein 31
FBXO38 F-box protein 38
FBXO39 F-box protein 39
FBXO4 F-box protein 4
FBXO44 F-box protein 44
FBXO48 F-box protein 48
FBXO6 F-box protein 6
FBXO9 F-box protein 9
FBXW11 F-box and WD repeat domain containing 11
FBXW4 F-box and WD repeat domain containing 4
FBXW5 F-box and WD repeat domain containing 5
FBXW7 F-box and WD repeat domain containing 7, E3 ubiquitin protein ligase
KIF14 kinesin family member 14
NCCRP1 non-specific cytotoxic cell receptor protein 1 homolog (zebrafish)
RBX1 ring-box 1, E3 ubiquitin protein ligase
SKP1 S-phase kinase-associated protein 1
UXT ubiquitously-expressed, prefoldin-like chaperone