SCML4 Gene Set

Dataset CM4AI KOLF21J CRISPRi Gene Perturbation Atlas
Category transcriptomics
Type gene perturbation
Description Scm polycomb group protein like 4 (NCBI Entrez Gene Database, 256380)
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Genes

326 genes differentially expressed following the SCML4 gene perturbation from the CM4AI KOLF21J CRISPRi Gene Perturbation Atlas.

increased expression

Symbol Name Standardized Value
GJA9 gap junction protein, alpha 9, 59kDa 3.56068
MYOM3 myomesin 3 3.56068
NCKAP1L NCK-associated protein 1-like 3.56068
PCDH8 protocadherin 8 3.56068
GNAT2 guanine nucleotide binding protein (G protein), alpha transducing activity polypeptide 2 3.56068
SPNS2 spinster homolog 2 (Drosophila) 3.56068
PLK5 polo-like kinase 5 3.56068
LRRIQ4 leucine-rich repeats and IQ motif containing 4 3.56068
S100A1 S100 calcium binding protein A1 3.56068
COL15A1 collagen, type XV, alpha 1 3.56068
TAL2 T-cell acute lymphocytic leukemia 2 3.56068
SSTR5 somatostatin receptor 5 3.56068
HLF hepatic leukemia factor 3.56068
ELF5 E74-like factor 5 (ets domain transcription factor) 3.56068
SLC6A19 solute carrier family 6 (neutral amino acid transporter), member 19 3.56068
ZNF503 zinc finger protein 503 3.56068
USP26 ubiquitin specific peptidase 26 3.56068
CD1C CD1c molecule 3.56068
NDST4 N-deacetylase/N-sulfotransferase (heparan glucosaminyl) 4 3.56068
PDYN prodynorphin 3.56068
OR10A2 olfactory receptor, family 10, subfamily A, member 2 3.56068
SPINK14 serine peptidase inhibitor, Kazal type 14 (putative) 3.56068
LGALS4 lectin, galactoside-binding, soluble, 4 3.56068
NMUR1 neuromedin U receptor 1 3.56068
ZC2HC1B zinc finger, C2HC-type containing 1B 3.56068
OR6B1 olfactory receptor, family 6, subfamily B, member 1 3.56068
IRX1 iroquois homeobox 1 3.56068
PASD1 PAS domain containing 1 3.56068
TMEM88 transmembrane protein 88 3.56068
KCNK15 potassium channel, two pore domain subfamily K, member 15 3.56068
MSANTD1 Myb/SANT-like DNA-binding domain containing 1 3.56068
PPP1R3A protein phosphatase 1, regulatory subunit 3A 3.56068
TGM1 transglutaminase 1 3.56068
WFDC13 WAP four-disulfide core domain 13 3.56068
IGFN1 immunoglobulin-like and fibronectin type III domain containing 1 3.56068
HIC1 hypermethylated in cancer 1 3.56068
TP53INP2 tumor protein p53 inducible nuclear protein 2 3.56068
FGF7 fibroblast growth factor 7 3.56068
PCDHGA11 protocadherin gamma subfamily A, 11 3.56068
CD180 CD180 molecule 3.56068
SCIN scinderin 3.56068
NPR3 natriuretic peptide receptor 3 3.56068
DSPP dentin sialophosphoprotein 3.56068
RBP4 retinol binding protein 4, plasma 3.56068
IFNK interferon, kappa 3.56068
LOX lysyl oxidase 3.56068
SPMIP11 sperm microtubule inner protein 11 3.56068
HAO2 hydroxyacid oxidase 2 (long chain) 3.56068
PTH1R parathyroid hormone 1 receptor 3.56068
PROP1 PROP paired-like homeobox 1 3.56068
VN1R1 vomeronasal 1 receptor 1 3.56068
RD3 retinal degeneration 3 3.56068
IFIT1B interferon-induced protein with tetratricopeptide repeats 1B 3.56068
ASB4 ankyrin repeat and SOCS box containing 4 3.56068
GRAP GRB2-related adaptor protein 3.56068
TSPAN1 tetraspanin 1 3.56068
SELP selectin P (granule membrane protein 140kDa, antigen CD62) 3.56068
PLPP4 phospholipid phosphatase 4 3.56068
FAM240C family with sequence similarity 240 member C 3.56068
IRF2-DT IRF2 divergent transcript 3.56068
RPS21-DT RPS21 divergent transcript 3.56068
LOC122526780 uncharacterized LOC122526780 3.56068
TMEM238L transmembrane protein 238 like 3.56068
SMIM31 small integral membrane protein 31 3.56068
DUSP29 dual specificity phosphatase 29 3.56068
BRME1 break repair meiotic recombinase recruitment factor 1 3.56068
CABCOCO1 ciliary associated calcium binding coiled-coil 1 3.56068
MAGIX MAGI family member, X-linked 3.56068
CNTN6 contactin 6 3.56068
DLK1 delta-like 1 homolog (Drosophila) 3.56068
TUBA3D tubulin, alpha 3d 3.56068
KLHL31 kelch-like family member 31 3.56068
PCDHA2 protocadherin alpha 2 3.56068
ZNF436 zinc finger protein 436 3.56068
TMEM229A transmembrane protein 229A 3.56068
TBX22 T-box 22 3.56068
HBA2 hemoglobin, alpha 2 3.56068
KBTBD13 kelch repeat and BTB (POZ) domain containing 13 3.56068
SYCP2 synaptonemal complex protein 2 3.56068
IRF5 interferon regulatory factor 5 3.56068
SH3TC1 SH3 domain and tetratricopeptide repeats 1 3.56068
FOXD4L3 forkhead box D4-like 3 3.56068
GPR85 G protein-coupled receptor 85 3.56068
OOSP1 oocyte secreted protein 1, pseudogene 3.56068
MTMR11 myotubularin related protein 11 3.56068
CNTFR ciliary neurotrophic factor receptor 3.56068
CELA2A chymotrypsin-like elastase family, member 2A 3.56068
ATP2B3 ATPase, Ca++ transporting, plasma membrane 3 3.56068
NPFF neuropeptide FF-amide peptide precursor 3.56068
SPDYC speedy/RINGO cell cycle regulator family member C 3.56068
PLVAP plasmalemma vesicle associated protein 3.56068
LCN1 lipocalin 1 3.56068
PPP1R14C protein phosphatase 1, regulatory (inhibitor) subunit 14C 3.56068
ZCCHC12 zinc finger, CCHC domain containing 12 3.56068
BRDT bromodomain, testis-specific 3.56068
FBXO40 F-box protein 40 3.56068
FAM135B family with sequence similarity 135, member B 3.56068
KCNK7 potassium channel, two pore domain subfamily K, member 7 3.56068
BCL2A1 BCL2-related protein A1 3.56068
PCDHGB1 protocadherin gamma subfamily B, 1 3.56068
SVOP SV2 related protein homolog (rat) 3.56068
ZNF365 zinc finger protein 365 3.56068
APOH apolipoprotein H (beta-2-glycoprotein I) 3.56068
STAB1 stabilin 1 3.56068
SMIM22 small integral membrane protein 22 3.56068
SAMD5 sterile alpha motif domain containing 5 3.56068
ERICH3 glutamate-rich 3 3.56068
DHH desert hedgehog 3.56068
TEKT1 tektin 1 3.56068
GOLGA6B golgin A6 family, member B 3.56068
CALHM1 calcium homeostasis modulator 1 3.56068
SULT2A1 sulfotransferase family, cytosolic, 2A, dehydroepiandrosterone (DHEA)-preferring, member 1 3.56068
CLEC4D C-type lectin domain family 4, member D 3.56068
DPRX divergent-paired related homeobox 3.56068
NUTM1 NUT midline carcinoma, family member 1 3.56068
FIBIN fin bud initiation factor homolog (zebrafish) 3.56068
DRD2 dopamine receptor D2 3.56068
KLHL1 kelch-like family member 1 3.56068
CLDN34 claudin 34 3.56068
LMOD2 leiomodin 2 (cardiac) 3.56068
RRH retinal pigment epithelium-derived rhodopsin homolog 3.56068
GP2 glycoprotein 2 (zymogen granule membrane) 3.56068
EDN3 endothelin 3 3.56068
GBA3 glucosidase, beta, acid 3 (gene/pseudogene) 3.56068
TH tyrosine hydroxylase 3.56068
TRPM5 transient receptor potential cation channel, subfamily M, member 5 3.56068
CD80 CD80 molecule 3.56068
ZBED6 zinc finger, BED-type containing 6 3.56068
CD8A CD8a molecule 3.56068
EPPIN epididymal peptidase inhibitor 3.56068
DUOXA1 dual oxidase maturation factor 1 3.56068
ADCY4 adenylate cyclase 4 3.56068
ADAM12 ADAM metallopeptidase domain 12 3.56068
GBX1 gastrulation brain homeobox 1 3.56068
FKBP1C FK506 binding protein 1C 3.56068
LRRC31 leucine rich repeat containing 31 3.56068
SLC17A2 solute carrier family 17, member 2 3.56068
TEX38 testis expressed 38 3.56068
GOLGA8M golgin A8 family, member M 3.56068
GCM1 glial cells missing homolog 1 (Drosophila) 3.56068
MTFR2 mitochondrial fission regulator 2 3.56068
LRRC74B leucine rich repeat containing 74B 3.56068
SOSTDC1 sclerostin domain containing 1 3.56068
KRT16 keratin 16, type I 3.56068
CMTM5 CKLF-like MARVEL transmembrane domain containing 5 3.56068
DND1 DND microRNA-mediated repression inhibitor 1 3.56068
HSPB9 heat shock protein, alpha-crystallin-related, B9 3.56068
TRIM7 tripartite motif containing 7 3.56068
RIBC1 RIB43A domain with coiled-coils 1 3.56068
SERPINB3 serpin peptidase inhibitor, clade B (ovalbumin), member 3 3.56068
SERPINB8 serpin peptidase inhibitor, clade B (ovalbumin), member 8 3.56068
ERP27 endoplasmic reticulum protein 27 3.56068
NUTM2G NUT family member 2G 3.56068
NUTM2B NUT family member 2B 3.56068
POU3F2 POU class 3 homeobox 2 3.56068
PSORS1C1 psoriasis susceptibility 1 candidate 1 3.56068
SIDT1 SID1 transmembrane family, member 1 3.56068
NOB1 NIN1/RPN12 binding protein 1 homolog (S. cerevisiae) 3.51462
CYP46A1 cytochrome P450, family 46, subfamily A, polypeptide 1 3.44158
MMAA methylmalonic aciduria (cobalamin deficiency) cblA type 3.44158
C5AR1 complement component 5a receptor 1 3.44158
MRPL41 mitochondrial ribosomal protein L41 3.42405
CPA6 carboxypeptidase A6 3.27508
WDR93 WD repeat domain 93 3.24637
DZANK1 double zinc ribbon and ankyrin repeat domains 1 3.10897
C3 complement component 3 3.05541
UTP4 UTP4 small subunit processome component 2.95608
BEGAIN brain-enriched guanylate kinase-associated 2.92815
PDE1B phosphodiesterase 1B, calmodulin-dependent 2.89234
ZNF577 zinc finger protein 577 2.82407
VANGL1 VANGL planar cell polarity protein 1 2.82158
SHISAL2A shisa like 2A 2.79248
DKC1 dyskeratosis congenita 1, dyskerin 2.75751
MLLT6 myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 6 2.73351
CYP2R1 cytochrome P450, family 2, subfamily R, polypeptide 1 2.57918
CLP1 cleavage and polyadenylation factor I subunit 1 2.56975
RNF13 ring finger protein 13 2.55062
ARHGAP18 Rho GTPase activating protein 18 2.51565
YIPF1 Yip1 domain family, member 1 2.50196
RAI14 retinoic acid induced 14 2.44926
NOS3 nitric oxide synthase 3 (endothelial cell) 2.43779
ZFP69 ZFP69 zinc finger protein 2.43779
PGBD4 piggyBac transposable element derived 4 2.43779
CRACDL CRACD like 2.43779
TOMM40L translocase of outer mitochondrial membrane 40 homolog (yeast)-like 2.43779
CLNK cytokine-dependent hematopoietic cell linker 2.43779
NPIPA6 nuclear pore complex interacting protein family, member A6 2.43779
SGMS2 sphingomyelin synthase 2 2.43779
OAZ2 ornithine decarboxylase antizyme 2 2.43422
HEXD hexosaminidase D 2.42937
CARD14 caspase recruitment domain family, member 14 2.42778
CGRRF1 cell growth regulator with ring finger domain 1 2.42365
TCAIM T cell activation inhibitor, mitochondrial 2.41712
CCDC78 coiled-coil domain containing 78 2.41638
AP4M1 adaptor-related protein complex 4, mu 1 subunit 2.41122
SHISA4 shisa family member 4 2.40415
STEEP1 STING1 ER exit protein 1 2.39266
TBC1D17 TBC1 domain family, member 17 2.39023
PDK3 pyruvate dehydrogenase kinase, isozyme 3 2.36934
RNF175 ring finger protein 175 2.35287
FKBP6 FK506 binding protein 6, 36kDa 2.34682
KCNIP4 Kv channel interacting protein 4 2.33195
FCGRT Fc fragment of IgG, receptor, transporter, alpha 2.33193
SLC25A15 solute carrier family 25 (mitochondrial carrier; ornithine transporter) member 15 2.32273
ARL4A ADP-ribosylation factor-like 4A 2.32222
ST14 suppression of tumorigenicity 14 (colon carcinoma) 2.30356
SPATA1 spermatogenesis associated 1 2.26658
CD2AP CD2-associated protein 2.23066
APLF aprataxin and PNKP like factor 2.22382
OSBPL5 oxysterol binding protein-like 5 2.21493
ZNF316 zinc finger protein 316 2.21429
ZNF776 zinc finger protein 776 2.19064
C6ORF136 chromosome 6 open reading frame 136 2.1853
PTPN9 protein tyrosine phosphatase, non-receptor type 9 2.16896
KLF8 Kruppel-like factor 8 2.12718
KCNH2 potassium channel, voltage gated eag related subfamily H, member 2 2.0849
GPATCH4 G patch domain containing 4 2.0676
CHEK1 checkpoint kinase 1 2.05838
BANF1 barrier to autointegration factor 1 2.03301
MICOS10 mitochondrial contact site and cristae organizing system subunit 10 2.01951

decreased expression

Symbol Name Standardized Value
RPA4 replication protein A4, 30kDa -3.56068
SEMA6C sema domain, transmembrane domain (TM), and cytoplasmic domain, (semaphorin) 6C -3.56068
UNC13C unc-13 homolog C (C. elegans) -3.56068
EFCAB3 EF-hand calcium binding domain 3 -3.56068
NLRC4 NLR family, CARD domain containing 4 -3.56068
IL31RA interleukin 31 receptor A -3.56068
KCNJ11 potassium channel, inwardly rectifying subfamily J, member 11 -3.56068
FXYD2 FXYD domain containing ion transport regulator 2 -3.56068
FER1L6 fer-1-like family member 6 -3.56068
PSTPIP1 proline-serine-threonine phosphatase interacting protein 1 -3.56068
PTGDS prostaglandin D2 synthase 21kDa (brain) -3.56068
ANKRD37 ankyrin repeat domain 37 -3.56068
SPOCK2 sparc/osteonectin, cwcv and kazal-like domains proteoglycan (testican) 2 -3.56068
CYP4Z1 cytochrome P450, family 4, subfamily Z, polypeptide 1 -3.56068
PODNL1 podocan-like 1 -3.56068
CYP3A43 cytochrome P450, family 3, subfamily A, polypeptide 43 -3.56068
TRPM1 transient receptor potential cation channel, subfamily M, member 1 -3.56068
MFNG MFNG O-fucosylpeptide 3-beta-N-acetylglucosaminyltransferase -3.56068
SCT secretin -3.56068
CDH15 cadherin 15, type 1, M-cadherin (myotubule) -3.56068
SPMIP8 sperm microtubule inner protein 8 -3.56068
ETFBKMT electron transfer flavoprotein subunit beta lysine methyltransferase -3.56068
DEGS2 delta(4)-desaturase, sphingolipid 2 -3.56068
PARVG parvin, gamma -3.56068
XCL1 chemokine (C motif) ligand 1 -3.56068
TMEM151A transmembrane protein 151A -3.56068
MOG myelin oligodendrocyte glycoprotein -3.56068
GPR68 G protein-coupled receptor 68 -3.56068
PRRT1 proline-rich transmembrane protein 1 -3.56068
AMH anti-Mullerian hormone -3.56068
TM4SF1 transmembrane 4 L six family member 1 -3.56068
CRYGN crystallin, gamma N -3.56068
SLC31A2 solute carrier family 31 (copper transporter), member 2 -3.56068
ALOX15 arachidonate 15-lipoxygenase -3.56068
GRIN3B glutamate receptor, ionotropic, N-methyl-D-aspartate 3B -3.56068
RPL39L ribosomal protein L39-like -3.55082
CTHRC1 collagen triple helix repeat containing 1 -3.46562
TCERG1 transcription elongation regulator 1 -3.40521
DRG2 developmentally regulated GTP binding protein 2 -3.365
RAB11FIP3 RAB11 family interacting protein 3 (class II) -3.24637
FGF2 fibroblast growth factor 2 (basic) -3.16867
POP5 processing of precursor 5, ribonuclease P/MRP subunit (S. cerevisiae) -3.10941
ALG11 ALG11, alpha-1,2-mannosyltransferase -2.95608
PPP1R12C protein phosphatase 1, regulatory subunit 12C -2.92815
KLRB1 killer cell lectin-like receptor subfamily B, member 1 -2.89859
RXRB retinoid X receptor, beta -2.89859
CCR10 chemokine (C-C motif) receptor 10 -2.82158
SMG7 SMG7 nonsense mediated mRNA decay factor -2.80853
ADA adenosine deaminase -2.77041
TSC22D2 TSC22 domain family, member 2 -2.74579
ZNF385C zinc finger protein 385C -2.57356
LTV1 LTV1 ribosome biogenesis factor -2.5705
ARRB2 arrestin, beta 2 -2.56217
SLC16A13 solute carrier family 16, member 13 -2.55753
HOMER3 homer scaffolding protein 3 -2.53799
HNRNPH3 heterogeneous nuclear ribonucleoprotein H3 (2H9) -2.53209
GPR3 G protein-coupled receptor 3 -2.52296
SPOPL speckle-type POZ protein-like -2.52296
OTX1 orthodenticle homeobox 1 -2.52176
TPM4 tropomyosin 4 -2.50255
VSTM5 V-set and transmembrane domain containing 5 -2.43779
NTNG2 netrin G2 -2.43779
ZC3H12A zinc finger CCCH-type containing 12A -2.43779
CDH26 cadherin 26 -2.43779
CARMIL3 capping protein regulator and myosin 1 linker 3 -2.43779
HSPB6 heat shock protein, alpha-crystallin-related, B6 -2.43779
ZNF732 zinc finger protein 732 -2.41622
TNS1-AS1 TNS1 antisense RNA 1 -2.41217
GBA1 glucosylceramidase beta 1 -2.40494
ADH6 alcohol dehydrogenase 6 (class V) -2.38345
JSRP1 junctional sarcoplasmic reticulum protein 1 -2.38345
FCRL5 Fc receptor-like 5 -2.38345
KATNB1 katanin p80 (WD repeat containing) subunit B 1 -2.38229
COL8A1 collagen, type VIII, alpha 1 -2.38065
CCNYL1 cyclin Y-like 1 -2.37927
RHBG Rh family, B glycoprotein (gene/pseudogene) -2.34902
NGF nerve growth factor (beta polypeptide) -2.34902
ANKRA2 ankyrin repeat, family A (RFXANK-like), 2 -2.34682
MATN3 matrilin 3 -2.33748
GRHL1 grainyhead-like 1 (Drosophila) -2.33086
MAP1LC3B2 microtubule-associated protein 1 light chain 3 beta 2 -2.33086
VAMP5 vesicle-associated membrane protein 5 -2.29522
RABGAP1L RAB GTPase activating protein 1-like -2.27121
KLHDC4 kelch domain containing 4 -2.25257
PTH2R parathyroid hormone 2 receptor -2.24614
EFNB1 ephrin-B1 -2.24614
FSIP2 fibrous sheath interacting protein 2 -2.23924
GPATCH11 G patch domain containing 11 -2.22382
USP25 ubiquitin specific peptidase 25 -2.22382
ZNF18 zinc finger protein 18 -2.21429
TMEM276 transmembrane protein 276 -2.19711
RSAD1 radical S-adenosyl methionine domain containing 1 -2.18645
PCBD2 pterin-4 alpha-carbinolamine dehydratase/dimerization cofactor of hepatocyte nuclear factor 1 alpha (TCF1) 2 -2.16896
UBXN2B UBX domain protein 2B -2.16896
ZFAND4 zinc finger, AN1-type domain 4 -2.14766
CLDND2 claudin domain containing 2 -2.13153
RNF126 ring finger protein 126 -2.13153
RABL2A RAB, member of RAS oncogene family-like 2A -2.12932
SMPD4 sphingomyelin phosphodiesterase 4, neutral membrane (neutral sphingomyelinase-3) -2.10033
SIPA1L2 signal-induced proliferation-associated 1 like 2 -2.07995
SEM1 SEM1 26S proteasome subunit -2.05178
RER1 retention in endoplasmic reticulum sorting receptor 1 -2.04391
PRDM15 PR domain containing 15 -2.04204
EPM2AIP1 EPM2A (laforin) interacting protein 1 -2.04204
LTN1 listerin E3 ubiquitin protein ligase 1 -2.03245
ALG8 ALG8, alpha-1,3-glucosyltransferase -2.01608