SCN2A Gene Set

Dataset LINCS L1000 CMAP CRISPR Knockout Consensus Signatures
Category transcriptomics
Type gene perturbation
Description sodium channel, voltage gated, type II alpha subunit|Voltage-gated sodium channels are transmembrane glycoprotein complexes composed of a large alpha subunit with 24 transmembrane domains and one or more regulatory beta subunits. They are responsible for the generation and propagation of action potentials in neurons and muscle. This gene encodes one member of the sodium channel alpha subunit gene family. It is heterogeneously expressed in the brain, and mutations in this gene have been linked to several seizure disorders. Several alternatively spliced transcript variants of this gene have been described, but the full-length nature of some of these variants has not been determined. [provided by RefSeq, Jul 2008] (NCBI Entrez Gene Database, 6326)
External Link https://ncbi.nlm.nih.gov/gene/6326
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Genes

499 genes differentially expressed following the SCN2A gene perturbation from the LINCS L1000 CMAP CRISPR Knockout Consensus Signatures dataset.

increased expression

Symbol Name Standardized Value
RPS4Y1 ribosomal protein S4, Y-linked 1 0.0276608
EIF1AY eukaryotic translation initiation factor 1A, Y-linked 0.0230737
KDM5D lysine (K)-specific demethylase 5D 0.0223769
SEPP1 selenoprotein P, plasma, 1 0.0143557
SERPINF1 serpin peptidase inhibitor, clade F (alpha-2 antiplasmin, pigment epithelium derived factor), member 1 0.0132348
RNASE1 ribonuclease, RNase A family, 1 (pancreatic) 0.0128565
EMP3 epithelial membrane protein 3 0.0126365
COL3A1 collagen, type III, alpha 1 0.0125804
DDX3Y DEAD (Asp-Glu-Ala-Asp) box helicase 3, Y-linked 0.012566
COLEC12 collectin sub-family member 12 0.0123495
IGFBP5 insulin-like growth factor binding protein 5 0.0121535
IGFBP2 insulin-like growth factor binding protein 2, 36kDa 0.0120568
CD320 CD320 molecule 0.0116582
PRKAR2B protein kinase, cAMP-dependent, regulatory, type II, beta 0.0109497
ANPEP alanyl (membrane) aminopeptidase 0.0106499
DCXR dicarbonyl/L-xylulose reductase 0.0105611
TNC tenascin C 0.0105587
FCGBP Fc fragment of IgG binding protein 0.0102296
LGALS1 lectin, galactoside-binding, soluble, 1 0.0101753
IQGAP2 IQ motif containing GTPase activating protein 2 0.0100475
TFF3 trefoil factor 3 (intestinal) 0.00983993
ECI2 enoyl-CoA delta isomerase 2 0.00972757
NTS neurotensin 0.00970604
PDGFRA platelet-derived growth factor receptor, alpha polypeptide 0.00964375
RAMP1 receptor (G protein-coupled) activity modifying protein 1 0.00956213
CD209 CD209 molecule 0.00937251
SDC2 syndecan 2 0.0093417
CP ceruloplasmin (ferroxidase) 0.00917392
NPM3 nucleophosmin/nucleoplasmin 3 0.00917342
BCHE butyrylcholinesterase 0.00912183
METTL7A methyltransferase like 7A 0.00905736
GNA11 guanine nucleotide binding protein (G protein), alpha 11 (Gq class) 0.00890723
CPVL carboxypeptidase, vitellogenic-like 0.00886418
COL1A2 collagen, type I, alpha 2 0.00884193
WWTR1 WW domain containing transcription regulator 1 0.00882516
POLE2 polymerase (DNA directed), epsilon 2, accessory subunit 0.00882424
CD99 CD99 molecule 0.00881633
PMP22 peripheral myelin protein 22 0.00879453
A2M alpha-2-macroglobulin 0.00871761
IGF1 insulin-like growth factor 1 (somatomedin C) 0.00870518
IMPA2 inositol(myo)-1(or 4)-monophosphatase 2 0.00858734
VKORC1 vitamin K epoxide reductase complex, subunit 1 0.00854502
PCOLCE procollagen C-endopeptidase enhancer 0.00851435
STAT3 signal transducer and activator of transcription 3 (acute-phase response factor) 0.00848505
SPON2 spondin 2, extracellular matrix protein 0.00845984
AKR7A3 aldo-keto reductase family 7, member A3 (aflatoxin aldehyde reductase) 0.00845229
HOXC6 homeobox C6 0.00842498
HOXB2 homeobox B2 0.00840835
BATF3 basic leucine zipper transcription factor, ATF-like 3 0.00838318
SPRY1 sprouty homolog 1, antagonist of FGF signaling (Drosophila) 0.00825043
F13A1 coagulation factor XIII, A1 polypeptide 0.00822963
NUSAP1 nucleolar and spindle associated protein 1 0.00820662
MGP matrix Gla protein 0.00820282
NIPSNAP2 nipsnap homolog 2 0.00819635
TUBB2A tubulin, beta 2A class IIa 0.0081733
CPM carboxypeptidase M 0.00813928
GAS1 growth arrest-specific 1 0.00813305
SUB1 SUB1 homolog (S. cerevisiae) 0.00812849
KANK2 KN motif and ankyrin repeat domains 2 0.00802912
OLFM1 olfactomedin 1 0.00801568
MAOA monoamine oxidase A 0.00800063
PTGER3 prostaglandin E receptor 3 (subtype EP3) 0.00794653
PLAT plasminogen activator, tissue 0.00793742
GATM glycine amidinotransferase (L-arginine:glycine amidinotransferase) 0.00792058
LSM7 LSM7 homolog, U6 small nuclear RNA associated (S. cerevisiae) 0.00791753
HMG20B high mobility group 20B 0.00790066
COL6A2 collagen, type VI, alpha 2 0.00790059
ARID4A AT rich interactive domain 4A (RBP1-like) 0.00789918
C1R complement component 1, r subcomponent 0.00789573
LRIG1 leucine-rich repeats and immunoglobulin-like domains 1 0.00787826
SRGN serglycin 0.00782027
CAMK1 calcium/calmodulin-dependent protein kinase I 0.00780308
SFRP1 secreted frizzled-related protein 1 0.00778602
NID1 nidogen 1 0.00776762
AKR7A2 aldo-keto reductase family 7, member A2 (aflatoxin aldehyde reductase) 0.00773309
ANXA6 annexin A6 0.00769838
RAPSN receptor-associated protein of the synapse 0.00768099
COL5A1 collagen, type V, alpha 1 0.007663
TMSB15A thymosin beta 15a 0.00761184
HNMT histamine N-methyltransferase 0.0076091
HMGB3 high mobility group box 3 0.00757789
CRLF1 cytokine receptor-like factor 1 0.00755828
RNF167 ring finger protein 167 0.00754186
FIS1 fission 1 (mitochondrial outer membrane) homolog (S. cerevisiae) 0.00753611
PTPRN2 protein tyrosine phosphatase, receptor type, N polypeptide 2 0.00751888
AKT1 v-akt murine thymoma viral oncogene homolog 1 0.00749676
GOLM1 golgi membrane protein 1 0.00749131
GSTA4 glutathione S-transferase alpha 4 0.0074685
PCGF2 polycomb group ring finger 2 0.007419
DEGS1 delta(4)-desaturase, sphingolipid 1 0.00741569
SUCLG2 succinate-CoA ligase, GDP-forming, beta subunit 0.0074095
MS4A4A membrane-spanning 4-domains, subfamily A, member 4A 0.00738462
SEPTIN10 septin 10 0.00738036
CFH complement factor H 0.00736719
RTN2 reticulon 2 0.00734991
DPYD dihydropyrimidine dehydrogenase 0.00733259
MS4A6A membrane-spanning 4-domains, subfamily A, member 6A 0.00728223
SLC25A11 solute carrier family 25 (mitochondrial carrier; oxoglutarate carrier), member 11 0.00722757
ZCCHC24 zinc finger, CCHC domain containing 24 0.00718098
SPON1 spondin 1, extracellular matrix protein 0.00717805
BST2 bone marrow stromal cell antigen 2 0.00716411
FLNC filamin C, gamma 0.00715718
ALDH1A2 aldehyde dehydrogenase 1 family, member A2 0.00714002
DNASE1L3 deoxyribonuclease I-like 3 0.00709945
CPS1 carbamoyl-phosphate synthase 1, mitochondrial 0.00707836
LAMA4 laminin, alpha 4 0.007072
CLEC11A C-type lectin domain family 11, member A 0.00700909
GPR183 G protein-coupled receptor 183 0.00700593
MRPL12 mitochondrial ribosomal protein L12 0.00696081
C1ORF115 chromosome 1 open reading frame 115 0.00693554
CD302 CD302 molecule 0.00689608
TFPI tissue factor pathway inhibitor (lipoprotein-associated coagulation inhibitor) 0.00688241
FXYD6 FXYD domain containing ion transport regulator 6 0.00685639
EPHB2 EPH receptor B2 0.00685535
KCND3 potassium channel, voltage gated Shal related subfamily D, member 3 0.00684726
CD300A CD300a molecule 0.00683977
CFI complement factor I 0.00682235
SLC2A4RG SLC2A4 regulator 0.00681566
CENPX centromere protein X 0.00679866
LYVE1 lymphatic vessel endothelial hyaluronan receptor 1 0.00679571
PDGFRL platelet-derived growth factor receptor-like 0.00679161
CDC25B cell division cycle 25B 0.00673797
IDH2 isocitrate dehydrogenase 2 (NADP+), mitochondrial 0.00672826
BNIP3 BCL2/adenovirus E1B 19kDa interacting protein 3 0.0067265
FADS1 fatty acid desaturase 1 0.00671301
ETFB electron-transfer-flavoprotein, beta polypeptide 0.00668197
FCGR2B Fc fragment of IgG, low affinity IIb, receptor (CD32) 0.00666193
PCLAF PCNA clamp associated factor 0.00665374
UBE2S ubiquitin-conjugating enzyme E2S 0.00663078
RNH1 ribonuclease/angiogenin inhibitor 1 0.00662977
PLA2G2A phospholipase A2, group IIA (platelets, synovial fluid) 0.00662446
DIXDC1 DIX domain containing 1 0.0066207
PLOD2 procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2 0.0065863
SLC43A3 solute carrier family 43, member 3 0.00657934
ALDH1A3 aldehyde dehydrogenase 1 family, member A3 0.00657419
P4HB prolyl 4-hydroxylase, beta polypeptide 0.00657318
NES nestin 0.00657048
DCHS1 dachsous cadherin-related 1 0.0065651
LMNB2 lamin B2 0.00656301
PSRC1 proline/serine-rich coiled-coil 1 0.00655173
NREP neuronal regeneration related protein 0.00654875
IFITM2 interferon induced transmembrane protein 2 0.00653878
RPA3 replication protein A3, 14kDa 0.0065293
TMEM14A transmembrane protein 14A 0.00652294
PLTP phospholipid transfer protein 0.00651727
CXCL14 chemokine (C-X-C motif) ligand 14 0.00649358
PEG3 paternally expressed 3 0.00648973
NCAPD3 non-SMC condensin II complex, subunit D3 0.00648152
GAMT guanidinoacetate N-methyltransferase 0.00646169
CDC42EP4 CDC42 effector protein (Rho GTPase binding) 4 0.00645613
SRPX sushi-repeat containing protein, X-linked 0.0064488
RAB40B RAB40B, member RAS oncogene family 0.00644495
BIRC5 baculoviral IAP repeat containing 5 0.00643136
GPX1 glutathione peroxidase 1 0.00641898
LST1 leukocyte specific transcript 1 0.00640494
APLNR apelin receptor 0.00639148
LIG1 ligase I, DNA, ATP-dependent 0.00638521
NAT1 N-acetyltransferase 1 (arylamine N-acetyltransferase) 0.00637862
DENND2B DENN domain containing 2B 0.0063755
SLIT2 slit homolog 2 (Drosophila) 0.00636141
CD93 CD93 molecule 0.00635532
SIVA1 SIVA1, apoptosis-inducing factor 0.00634809
CHODL chondrolectin 0.00634403
TMEM106C transmembrane protein 106C 0.00634043
MXRA8 matrix-remodelling associated 8 0.00633512
FCGR2A Fc fragment of IgG, low affinity IIa, receptor (CD32) 0.006319
CHN2 chimerin 2 0.00631407
TTC38 tetratricopeptide repeat domain 38 0.00630739
SPARCL1 SPARC-like 1 (hevin) 0.00627176
HLTF helicase-like transcription factor 0.00626815
ATP5F1D ATP synthase F1 subunit delta 0.00626149
CDC45 cell division cycle 45 0.00625901
TNNT1 troponin T type 1 (skeletal, slow) 0.00625239
METRN meteorin, glial cell differentiation regulator 0.00624597
PLXDC1 plexin domain containing 1 0.00624254
NCAM1 neural cell adhesion molecule 1 0.00623302
CCL13 chemokine (C-C motif) ligand 13 0.00622717
SELENOW selenoprotein W 0.00622518
ACACA acetyl-CoA carboxylase alpha 0.00622328
MDFIC MyoD family inhibitor domain containing 0.00620048
SCARA3 scavenger receptor class A, member 3 0.00619563
NQO2 NAD(P)H dehydrogenase, quinone 2 0.00619026
CDCA4 cell division cycle associated 4 0.00616371
ANP32E acidic (leucine-rich) nuclear phosphoprotein 32 family, member E 0.00615184
BCL7C B-cell CLL/lymphoma 7C 0.00614778
GSTT1 glutathione S-transferase theta 1 0.00613492
OGFOD3 2-oxoglutarate and iron-dependent oxygenase domain containing 3 0.00613095
PTP4A3 protein tyrosine phosphatase type IVA, member 3 0.00611385
LRRC17 leucine rich repeat containing 17 0.00609688
HLA-DPA1 major histocompatibility complex, class II, DP alpha 1 0.00609688
CPQ carboxypeptidase Q 0.00609361
LCP2 lymphocyte cytosolic protein 2 (SH2 domain containing leukocyte protein of 76kDa) 0.0060875
STMN1 stathmin 1 0.00607812
CDKN2C cyclin-dependent kinase inhibitor 2C (p18, inhibits CDK4) 0.00606595
PDLIM3 PDZ and LIM domain 3 0.00605103
PIP4K2B phosphatidylinositol-5-phosphate 4-kinase, type II, beta 0.00604442
TMEM109 transmembrane protein 109 0.00604085
ZBTB18 zinc finger and BTB domain containing 18 0.00603257
USP9Y ubiquitin specific peptidase 9, Y-linked 0.00603225
EML3 echinoderm microtubule associated protein like 3 0.00603162
EVL Enah/Vasp-like 0.00601477
COX7A1 cytochrome c oxidase subunit VIIa polypeptide 1 (muscle) 0.00600147
PPA2 pyrophosphatase (inorganic) 2 0.00597965
DDR2 discoidin domain receptor tyrosine kinase 2 0.00597828
APOC2 apolipoprotein C-II 0.00597807
FKBP1B FK506 binding protein 1B, 12.6 kDa 0.00597793
B3GNT1 0.00597493
SDHD succinate dehydrogenase complex, subunit D, integral membrane protein 0.00594462
ITM2A integral membrane protein 2A 0.0059358
SKP2 S-phase kinase-associated protein 2, E3 ubiquitin protein ligase 0.00593285
PIMREG PICALM interacting mitotic regulator 0.00591892
FAM3C family with sequence similarity 3, member C 0.0059164
CLCA1 chloride channel accessory 1 0.00591593
TMEM45A transmembrane protein 45A 0.00590361
SDHAF3 succinate dehydrogenase complex assembly factor 3 0.00590335
POLR2L polymerase (RNA) II (DNA directed) polypeptide L, 7.6kDa 0.00590256
TOP2A topoisomerase (DNA) II alpha 170kDa 0.00589819
RNF144A ring finger protein 144A 0.0058826
PPP1R1A protein phosphatase 1, regulatory (inhibitor) subunit 1A 0.00588109
KIF1B kinesin family member 1B 0.00587234
ATP5G1 ATP synthase, H+ transporting, mitochondrial Fo complex, subunit C1 (subunit 9) 0.00586579
SSBP2 single-stranded DNA binding protein 2 0.00585391
LOXL1 lysyl oxidase-like 1 0.00585255
ATXN1 ataxin 1 0.00585183
ITGB3BP integrin beta 3 binding protein (beta3-endonexin) 0.0058439
BIN2 bridging integrator 2 0.00583876
PIR pirin (iron-binding nuclear protein) 0.0058351
RACGAP1 Rac GTPase activating protein 1 0.00582762
ADGRA2 adhesion G protein-coupled receptor A2 0.0058233
EMILIN1 elastin microfibril interfacer 1 0.00582024
TWIST1 twist family bHLH transcription factor 1 0.00579741
CISH cytokine inducible SH2-containing protein 0.00579537
LY86 lymphocyte antigen 86 0.00578724
HSD17B8 hydroxysteroid (17-beta) dehydrogenase 8 0.0057863
F2R coagulation factor II (thrombin) receptor 0.00577687
DCTN3 dynactin 3 (p22) 0.0057739
NSMF NMDA receptor synaptonuclear signaling and neuronal migration factor 0.0057737
COL5A2 collagen, type V, alpha 2 0.00576334
RUVBL1 RuvB-like AAA ATPase 1 0.00575226
CYBRD1 cytochrome b reductase 1 0.00574748
MT1E metallothionein 1E 0.00574433
NME3 NME/NM23 nucleoside diphosphate kinase 3 0.00573389
NR2F1 nuclear receptor subfamily 2, group F, member 1 0.00573272
PRKDC protein kinase, DNA-activated, catalytic polypeptide 0.00573048
PDGFRB platelet-derived growth factor receptor, beta polypeptide 0.00572883
STEAP1 six transmembrane epithelial antigen of the prostate 1 0.00571706
EPHX1 epoxide hydrolase 1, microsomal (xenobiotic) 0.00571673
MTMR11 myotubularin related protein 11 0.00570878
MSN moesin 0.00567991
BACE1 beta-site APP-cleaving enzyme 1 0.0056371

decreased expression

Symbol Name Standardized Value
XIC X chromosome inactivation center -0.0209328
CHAC1 ChaC glutathione-specific gamma-glutamylcyclotransferase 1 -0.0198091
GNAS GNAS complex locus -0.0158294
ATF3 activating transcription factor 3 -0.0155779
MAP7 microtubule-associated protein 7 -0.0153027
HSPA1A heat shock 70kDa protein 1A -0.0150503
TFPI2 tissue factor pathway inhibitor 2 -0.0150311
CDKN1A cyclin-dependent kinase inhibitor 1A (p21, Cip1) -0.0144657
GPRC5A G protein-coupled receptor, class C, group 5, member A -0.0128693
ANXA1 annexin A1 -0.0127838
AMIGO2 adhesion molecule with Ig-like domain 2 -0.0120444
S100A10 S100 calcium binding protein A10 -0.0118095
HSPH1 heat shock 105kDa/110kDa protein 1 -0.0118028
S100A8 S100 calcium binding protein A8 -0.0113576
CCNA2 cyclin A2 -0.0112193
RGS13 regulator of G-protein signaling 13 -0.0111162
SMC1A structural maintenance of chromosomes 1A -0.0108915
SPRR3 small proline-rich protein 3 -0.0107498
CSTA cystatin A (stefin A) -0.0106937
HIST1H2BD histone cluster 1, H2bd -0.0106177
KRT13 keratin 13, type I -0.0105797
DKK1 dickkopf WNT signaling pathway inhibitor 1 -0.0105397
PERP PERP, TP53 apoptosis effector -0.0105201
CRISP3 cysteine-rich secretory protein 3 -0.0104898
ISG20 interferon stimulated exonuclease gene 20kDa -0.0102051
ZNF165 zinc finger protein 165 -0.010182
ASNS asparagine synthetase (glutamine-hydrolyzing) -0.01004
CXCL2 chemokine (C-X-C motif) ligand 2 -0.00999142
IFI27 interferon, alpha-inducible protein 27 -0.00997051
S100P S100 calcium binding protein P -0.00988453
KRT19 keratin 19, type I -0.00987107
TACSTD2 tumor-associated calcium signal transducer 2 -0.00980811
SLC38A2 solute carrier family 38, member 2 -0.00977596
TRIM29 tripartite motif containing 29 -0.00971255
MICAL2 microtubule associated monooxygenase, calponin and LIM domain containing 2 -0.00970437
NEBL nebulette -0.00950143
KRT7 keratin 7, type II -0.00942861
ANXA3 annexin A3 -0.0094272
HIST1H2AC histone cluster 1, H2ac -0.00935264
EGR1 early growth response 1 -0.00933264
ALDH5A1 aldehyde dehydrogenase 5 family, member A1 -0.00927059
KRT15 keratin 15, type I -0.00924846
SLC6A14 solute carrier family 6 (amino acid transporter), member 14 -0.00923408
HSP90AA1 heat shock protein 90kDa alpha (cytosolic), class A member 1 -0.0092296
RELB v-rel avian reticuloendotheliosis viral oncogene homolog B -0.00922333
GALNT3 polypeptide N-acetylgalactosaminyltransferase 3 -0.00919408
ADIRF adipogenesis regulatory factor -0.00919358
EPHA2 EPH receptor A2 -0.00913449
DDIT3 DNA-damage-inducible transcript 3 -0.00909083
KRT14 keratin 14, type I -0.00905713
RND3 Rho family GTPase 3 -0.00903012
DDX3X DEAD (Asp-Glu-Ala-Asp) box helicase 3, X-linked -0.00899576
PEG10 paternally expressed 10 -0.00897101
DHRS2 dehydrogenase/reductase (SDR family) member 2 -0.00896462
ALCAM activated leukocyte cell adhesion molecule -0.00896134
FLRT3 fibronectin leucine rich transmembrane protein 3 -0.00890363
MPO myeloperoxidase -0.00885337
CEMIP cell migration inducing protein, hyaluronan binding -0.00885336
GALNT14 polypeptide N-acetylgalactosaminyltransferase 14 -0.0088194
ZBED2 zinc finger, BED-type containing 2 -0.00876636
CXADR coxsackie virus and adenovirus receptor -0.0087217
LAMC2 laminin, gamma 2 -0.0086924
CEACAM6 carcinoembryonic antigen-related cell adhesion molecule 6 (non-specific cross reacting antigen) -0.00865743
SLC38A1 solute carrier family 38, member 1 -0.00865285
SIK1 salt-inducible kinase 1 -0.00863984
TUFT1 tuftelin 1 -0.00860801
MS4A1 membrane-spanning 4-domains, subfamily A, member 1 -0.00860306
KRT5 keratin 5, type II -0.00853633
CYP4B1 cytochrome P450, family 4, subfamily B, polypeptide 1 -0.00852539
PLEKHM1 pleckstrin homology domain containing, family M (with RUN domain) member 1 -0.00851163
SERPINB5 serpin peptidase inhibitor, clade B (ovalbumin), member 5 -0.00848962
KLF5 Kruppel-like factor 5 (intestinal) -0.00846167
MAP1LC3B microtubule-associated protein 1 light chain 3 beta -0.00845963
RFTN1 raftlin, lipid raft linker 1 -0.00842578
PPP1R15A protein phosphatase 1, regulatory subunit 15A -0.00840699
CTSD cathepsin D -0.0083826
WARS1 tryptophanyl-tRNA synthetase 1 -0.00828057
EHD3 EH-domain containing 3 -0.00826983
PAX5 paired box 5 -0.0081977
DKK3 dickkopf WNT signaling pathway inhibitor 3 -0.00819028
EIF2S3 eukaryotic translation initiation factor 2, subunit 3 gamma, 52kDa -0.00812405
SLPI secretory leukocyte peptidase inhibitor -0.00806793
SCEL sciellin -0.00805331
GADD45A growth arrest and DNA-damage-inducible, alpha -0.00792303
INPP4B inositol polyphosphate-4-phosphatase, type II, 105kDa -0.0079117
CCN2 cellular communication network factor 2 -0.00787196
HSPA5 heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) -0.007858
S100A12 S100 calcium binding protein A12 -0.00778796
PPBP pro-platelet basic protein (chemokine (C-X-C motif) ligand 7) -0.00774229
CDV3 CDV3 homolog (mouse) -0.00773509
IL33R interleukin 33 receptor -0.00772578
KRT6A keratin 6A, type II -0.00771481
KRT81 keratin 81, type II -0.00766123
MET MET proto-oncogene, receptor tyrosine kinase -0.00765121
BHLHE41 basic helix-loop-helix family, member e41 -0.00764791
TRIB3 tribbles pseudokinase 3 -0.0076086
EPCAM epithelial cell adhesion molecule -0.00754333
BMP2 bone morphogenetic protein 2 -0.00754225
CYB5R2 cytochrome b5 reductase 2 -0.00753183
KDM6A lysine (K)-specific demethylase 6A -0.00750362
AUTS2 autism susceptibility candidate 2 -0.00749362
RBM34 RNA binding motif protein 34 -0.00748019
TPD52L1 tumor protein D52-like 1 -0.00743414
KLK10 kallikrein-related peptidase 10 -0.00742507
TFRC transferrin receptor -0.0074194
GRN granulin -0.00740946
SP100 SP100 nuclear antigen -0.00738746
MFAP3L microfibrillar-associated protein 3-like -0.00736928
RTCA RNA 3'-terminal phosphate cyclase -0.00736721
BMP7 bone morphogenetic protein 7 -0.0073066
CLIC5 chloride intracellular channel 5 -0.00727688
OSBPL10 oxysterol binding protein-like 10 -0.00726443
VAMP8 vesicle-associated membrane protein 8 -0.0072497
STC2 stanniocalcin 2 -0.00724572
SLC1A1 solute carrier family 1 (neuronal/epithelial high affinity glutamate transporter, system Xag), member 1 -0.00722599
GABRP gamma-aminobutyric acid (GABA) A receptor, pi -0.00722214
CRCT1 cysteine-rich C-terminal 1 -0.00720618
ELF5 E74-like factor 5 (ets domain transcription factor) -0.00711109
L1CAM L1 cell adhesion molecule -0.00709983
NCOA3 nuclear receptor coactivator 3 -0.0070965
BTG2 BTG family, member 2 -0.00708495
SPINT1 serine peptidase inhibitor, Kunitz type 1 -0.00705171
ADGRG6 adhesion G protein-coupled receptor G6 -0.00705037
TNNC1 troponin C type 1 (slow) -0.00704555
TNFAIP3 tumor necrosis factor, alpha-induced protein 3 -0.00704314
DDX21 DEAD (Asp-Glu-Ala-Asp) box helicase 21 -0.00703717
ABLIM1 actin binding LIM protein 1 -0.00703108
NEU1 sialidase 1 (lysosomal sialidase) -0.00700193
ATP6V1D ATPase, H+ transporting, lysosomal 34kDa, V1 subunit D -0.00697957
MCL1 myeloid cell leukemia 1 -0.00697204
HBD hemoglobin, delta -0.00694636
ZFAND5 zinc finger, AN1-type domain 5 -0.00692117
TGFA transforming growth factor, alpha -0.00689901
EGFL6 EGF-like-domain, multiple 6 -0.00687273
IER5 immediate early response 5 -0.00686428
INAVA innate immunity activator -0.0068216
ITGA3 integrin, alpha 3 (antigen CD49C, alpha 3 subunit of VLA-3 receptor) -0.00678219
KLHL24 kelch-like family member 24 -0.00676594
CXCL13 chemokine (C-X-C motif) ligand 13 -0.00675138
SLC2A1 solute carrier family 2 (facilitated glucose transporter), member 1 -0.00674548
TSC22D1 TSC22 domain family, member 1 -0.00674209
CD9 CD9 molecule -0.00674193
DYNLL1 dynein, light chain, LC8-type 1 -0.0067365
DNAJA1 DnaJ (Hsp40) homolog, subfamily A, member 1 -0.00673075
AMOTL2 angiomotin like 2 -0.00672983
SLC7A5 solute carrier family 7 (amino acid transporter light chain, L system), member 5 -0.00672476
FERMT1 fermitin family member 1 -0.00669507
TAP1 transporter 1, ATP-binding cassette, sub-family B (MDR/TAP) -0.00668677
TPP1 tripeptidyl peptidase I -0.00668534
PAWR PRKC, apoptosis, WT1, regulator -0.00668473
NEDD9 neural precursor cell expressed, developmentally down-regulated 9 -0.00668436
COBLL1 cordon-bleu WH2 repeat protein-like 1 -0.00667965
SUPV3L1 suppressor of var1, 3-like 1 (S. cerevisiae) -0.00667948
MAP4K4 mitogen-activated protein kinase kinase kinase kinase 4 -0.00664942
MSLN mesothelin -0.00664849
CST1 cystatin SN -0.0066433
INHBA inhibin, beta A -0.00662541
RAB21 RAB21, member RAS oncogene family -0.00662456
POU2AF1 POU class 2 associating factor 1 -0.00662236
CXCL5 chemokine (C-X-C motif) ligand 5 -0.00661871
TNFRSF12A tumor necrosis factor receptor superfamily, member 12A -0.00661827
STX7 syntaxin 7 -0.00661612
TARP TCR gamma alternate reading frame protein -0.00661286
ESRP1 epithelial splicing regulatory protein 1 -0.00661016
CAB39 calcium binding protein 39 -0.00659026
OPTN optineurin -0.00658217
TIPARP TCDD-inducible poly(ADP-ribose) polymerase -0.00656109
TP63 tumor protein p63 -0.00655502
OFD1 oral-facial-digital syndrome 1 -0.00652568
KPNA4 karyopherin alpha 4 (importin alpha 3) -0.00648852
ASS1 argininosuccinate synthase 1 -0.00647993
RAB11FIP1 RAB11 family interacting protein 1 (class I) -0.00647327
CNTN1 contactin 1 -0.00647111
WAC WW domain containing adaptor with coiled-coil -0.00646343
SWAP70 SWAP switching B-cell complex 70kDa subunit -0.00643285
ADAM10 ADAM metallopeptidase domain 10 -0.00642749
GDF15 growth differentiation factor 15 -0.00639046
SPINT2 serine peptidase inhibitor, Kunitz type, 2 -0.00638004
SLC31A2 solute carrier family 31 (copper transporter), member 2 -0.0063755
PIK3IP1 phosphoinositide-3-kinase interacting protein 1 -0.00635017
CXCL11 chemokine (C-X-C motif) ligand 11 -0.00634532
HACD1 3-hydroxyacyl-CoA dehydratase 1 -0.00632586
GPNMB glycoprotein (transmembrane) nmb -0.00632401
SPRR1B small proline-rich protein 1B -0.00632387
GPR87 G protein-coupled receptor 87 -0.00631866
PKP1 plakophilin 1 -0.00631599
CLDN1 claudin 1 -0.00631577
BTF3P11 basic transcription factor 3 pseudogene 11 -0.00631343
TM4SF1 transmembrane 4 L six family member 1 -0.00630846
AQP3 aquaporin 3 (Gill blood group) -0.00629911
MYO6 myosin VI -0.00629729
EPS8L2 EPS8-like 2 -0.00629374
RGCC regulator of cell cycle -0.00628851
BANK1 B-cell scaffold protein with ankyrin repeats 1 -0.00628626
ZNF750 zinc finger protein 750 -0.00628516
CD55 CD55 molecule, decay accelerating factor for complement (Cromer blood group) -0.00628399
FABP4 fatty acid binding protein 4, adipocyte -0.00628273
HSPA6 heat shock 70kDa protein 6 (HSP70B') -0.00626776
ZFP36L2 ZFP36 ring finger protein-like 2 -0.00625637
SH3GLB1 SH3-domain GRB2-like endophilin B1 -0.00624152
FCN3 ficolin (collagen/fibrinogen domain containing) 3 -0.00623463
RNF128 ring finger protein 128, E3 ubiquitin protein ligase -0.00622782
SMAD3 SMAD family member 3 -0.00620855
IDI1 isopentenyl-diphosphate delta isomerase 1 -0.00620669
WDR26 WD repeat domain 26 -0.006199
PTHLH parathyroid hormone-like hormone -0.00617891
CMAHP cytidine monophospho-N-acetylneuraminic acid hydroxylase, pseudogene -0.00617398
SARS1 seryl-tRNA synthetase 1 -0.0061587
SGK1 serum/glucocorticoid regulated kinase 1 -0.00615064
HECA headcase homolog (Drosophila) -0.00614556
GARS1 glycyl-tRNA synthetase 1 -0.00613983
CPA3 carboxypeptidase A3 (mast cell) -0.00613134
GDI2 GDP dissociation inhibitor 2 -0.00613014
LPIN1 lipin 1 -0.00612184
ATP1B3 ATPase, Na+/K+ transporting, beta 3 polypeptide -0.00611738
YPEL5 yippee-like 5 (Drosophila) -0.00611069
UNC45A unc-45 homolog A (C. elegans) -0.00609304
MAGEA4 melanoma antigen family A4 -0.00607498
SPIB Spi-B transcription factor (Spi-1/PU.1 related) -0.0060698
ZNF804A zinc finger protein 804A -0.00603901
HSPD1 heat shock 60kDa protein 1 (chaperonin) -0.00602393
HSPB8 heat shock 22kDa protein 8 -0.0060238
PHLDA1 pleckstrin homology-like domain, family A, member 1 -0.0060209
PLK2 polo-like kinase 2 -0.00601894
SLCO3A1 solute carrier organic anion transporter family, member 3A1 -0.00601877
ARNT2 aryl-hydrocarbon receptor nuclear translocator 2 -0.00600243
SDC4 syndecan 4 -0.00599681
MKNK2 MAP kinase interacting serine/threonine kinase 2 -0.00599604
CLEC2D C-type lectin domain family 2, member D -0.00599487
FOS FBJ murine osteosarcoma viral oncogene homolog -0.00599326
MTF2 metal response element binding transcription factor 2 -0.00599235
YME1L1 YME1-like 1 ATPase -0.00598994
NPC1 Niemann-Pick disease, type C1 -0.00595893
CORO1C coronin, actin binding protein, 1C -0.00594161
SLC14A1 solute carrier family 14 (urea transporter), member 1 (Kidd blood group) -0.0059378
SCGB2A1 secretoglobin, family 2A, member 1 -0.00590932
APOLD1 apolipoprotein L domain containing 1 -0.00590251
ERP44 endoplasmic reticulum protein 44 -0.00590123
TNS3 tensin 3 -0.00590067
RASAL2 RAS protein activator like 2 -0.0058989
NEAT1 nuclear paraspeckle assembly transcript 1 (non-protein coding) -0.00588274
PTPRK protein tyrosine phosphatase, receptor type, K -0.00588091
WWC1 WW and C2 domain containing 1 -0.00587867
DEPTOR DEP domain containing MTOR-interacting protein -0.00587417
SLC2A5 solute carrier family 2 (facilitated glucose/fructose transporter), member 5 -0.00586852
CXCL8 chemokine (C-X-C motif) ligand 8 -0.00585747
WIPI1 WD repeat domain, phosphoinositide interacting 1 -0.00583744
AREG amphiregulin -0.00583151
C1ORF116 chromosome 1 open reading frame 116 -0.00583062