SCN8A Gene Set

Dataset LINCS L1000 CMAP CRISPR Knockout Consensus Signatures
Category transcriptomics
Type gene perturbation
Description sodium channel, voltage gated, type VIII alpha subunit|This gene encodes a member of the sodium channel alpha subunit gene family. The encoded protein forms the ion pore region of the voltage-gated sodium channel. This protein is essential for the rapid membrane depolarization that occurs during the formation of the action potential in excitable neurons. Mutations in this gene are associated with mental retardation, pancerebellar atrophy and ataxia. Alternate splicing results in multiple transcript variants.[provided by RefSeq, May 2010] (NCBI Entrez Gene Database, 6334)
External Link https://ncbi.nlm.nih.gov/gene/6334
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Genes

497 genes differentially expressed following the SCN8A gene perturbation from the LINCS L1000 CMAP CRISPR Knockout Consensus Signatures dataset.

increased expression

Symbol Name Standardized Value
NTS neurotensin 0.0175902
IKZF1 IKAROS family zinc finger 1 (Ikaros) 0.015885
LYZ lysozyme 0.0158762
S100P S100 calcium binding protein P 0.0149585
PTGS2 prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase) 0.0141401
CXCL9 chemokine (C-X-C motif) ligand 9 0.0136159
MYB v-myb avian myeloblastosis viral oncogene homolog 0.0130404
GPX2 glutathione peroxidase 2 0.012941
XIC X chromosome inactivation center 0.0122218
SORD sorbitol dehydrogenase 0.0121306
GZMB granzyme B (granzyme 2, cytotoxic T-lymphocyte-associated serine esterase 1) 0.0120826
CSF2RB colony stimulating factor 2 receptor, beta, low-affinity (granulocyte-macrophage) 0.011958
CXCL13 chemokine (C-X-C motif) ligand 13 0.0116521
PRF1 perforin 1 (pore forming protein) 0.0115916
CD320 CD320 molecule 0.0113619
SMC1A structural maintenance of chromosomes 1A 0.0112152
IL2RG interleukin 2 receptor, gamma 0.0111948
CHP1 calcineurin-like EF-hand protein 1 0.0111158
MNAT1 MNAT CDK-activating kinase assembly factor 1 0.0109829
TMEM158 transmembrane protein 158 (gene/pseudogene) 0.0109424
LEF1 lymphoid enhancer-binding factor 1 0.0105817
CHST2 carbohydrate (N-acetylglucosamine-6-O) sulfotransferase 2 0.0105694
TXNDC9 thioredoxin domain containing 9 0.0105271
CCP110 centriolar coiled coil protein 110kDa 0.0104039
CST7 cystatin F (leukocystatin) 0.0103789
FCER1G Fc fragment of IgE, high affinity I, receptor for; gamma polypeptide 0.0103189
CPA3 carboxypeptidase A3 (mast cell) 0.0102163
ADI1 acireductone dioxygenase 1 0.0101534
CEACAM6 carcinoembryonic antigen-related cell adhesion molecule 6 (non-specific cross reacting antigen) 0.0101179
CD3D CD3d molecule, delta (CD3-TCR complex) 0.0098876
TSPAN13 tetraspanin 13 0.00984717
RHOB ras homolog family member B 0.00982983
NEBL nebulette 0.00973138
UAP1 UDP-N-acetylglucosamine pyrophosphorylase 1 0.00952728
CELF2 CUGBP, Elav-like family member 2 0.00951153
LTF lactotransferrin 0.00948178
C1QB complement component 1, q subcomponent, B chain 0.00946363
FASN fatty acid synthase 0.00932037
LGR5 leucine-rich repeat containing G protein-coupled receptor 5 0.00931995
PIP5K1B phosphatidylinositol-4-phosphate 5-kinase, type I, beta 0.00929225
CD38 CD38 molecule 0.00927205
TPSAB1 tryptase alpha/beta 1 0.0091666
CEACAM5 carcinoembryonic antigen-related cell adhesion molecule 5 0.00911161
IL7R interleukin 7 receptor 0.0089571
FPR1 formyl peptide receptor 1 0.00893476
MAD2L1 MAD2 mitotic arrest deficient-like 1 (yeast) 0.00893101
PRDX2 peroxiredoxin 2 0.00880295
MAGEA3 melanoma antigen family A3 0.00867298
ITK IL2-inducible T-cell kinase 0.00864693
GCA grancalcin, EF-hand calcium binding protein 0.00859067
PIR pirin (iron-binding nuclear protein) 0.00858741
PCOLCE2 procollagen C-endopeptidase enhancer 2 0.00858343
FCGR3B Fc fragment of IgG, low affinity IIIb, receptor (CD16b) 0.00856484
CD2 CD2 molecule 0.00856164
GLUL glutamate-ammonia ligase 0.00853523
CACNA2D2 calcium channel, voltage-dependent, alpha 2/delta subunit 2 0.0085096
DLGAP5 discs, large (Drosophila) homolog-associated protein 5 0.00850776
MT1X metallothionein 1X 0.00846814
SELENBP1 selenium binding protein 1 0.00846456
CD9 CD9 molecule 0.00845024
TCN1 transcobalamin I (vitamin B12 binding protein, R binder family) 0.00843628
RELB v-rel avian reticuloendotheliosis viral oncogene homolog B 0.00839476
SLC27A2 solute carrier family 27 (fatty acid transporter), member 2 0.00836204
ID1 inhibitor of DNA binding 1, dominant negative helix-loop-helix protein 0.0083608
SPRY2 sprouty homolog 2 (Drosophila) 0.00830707
FYB1 FYN binding protein 1 0.00823118
STK26 serine/threonine protein kinase 26 0.00816693
DCXR dicarbonyl/L-xylulose reductase 0.00807094
HLA-DPA1 major histocompatibility complex, class II, DP alpha 1 0.00794513
COCH cochlin 0.0078827
APIP APAF1 interacting protein 0.00785724
GCLC glutamate-cysteine ligase, catalytic subunit 0.00783969
CST3 cystatin C 0.00783481
GZMA granzyme A (granzyme 1, cytotoxic T-lymphocyte-associated serine esterase 3) 0.0078156
SUB1 SUB1 homolog (S. cerevisiae) 0.00779713
XCL1 chemokine (C motif) ligand 1 0.00778373
FCGR2A Fc fragment of IgG, low affinity IIa, receptor (CD32) 0.00778224
GRSF1 G-rich RNA sequence binding factor 1 0.0077604
PTP4A2 protein tyrosine phosphatase type IVA, member 2 0.00774933
FCER1A Fc fragment of IgE, high affinity I, receptor for; alpha polypeptide 0.00774594
CCL19 chemokine (C-C motif) ligand 19 0.00769043
NAT1 N-acetyltransferase 1 (arylamine N-acetyltransferase) 0.00768851
CLC Charcot-Leyden crystal galectin 0.00768388
IL2RB interleukin 2 receptor, beta 0.00766701
RB1 retinoblastoma 1 0.0076289
COMP cartilage oligomeric matrix protein 0.00759076
NME4 NME/NM23 nucleoside diphosphate kinase 4 0.0075886
FAR2 fatty acyl CoA reductase 2 0.00758134
CD8A CD8a molecule 0.00755383
SMYD2 SET and MYND domain containing 2 0.007532
LTBP1 latent transforming growth factor beta binding protein 1 0.00743254
SERPINA1 serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 1 0.00740101
S100A12 S100 calcium binding protein A12 0.00739486
DUT deoxyuridine triphosphatase 0.00736971
ATP2A3 ATPase, Ca++ transporting, ubiquitous 0.00727376
SLC26A2 solute carrier family 26 (anion exchanger), member 2 0.00725502
JCHAIN joining chain of multimeric IgA and IgM 0.00720505
ROBO1 roundabout, axon guidance receptor, homolog 1 (Drosophila) 0.00720069
CD163 CD163 molecule 0.00715502
CXCL11 chemokine (C-X-C motif) ligand 11 0.00714704
SLC5A6 solute carrier family 5 (sodium/multivitamin and iodide cotransporter), member 6 0.00713814
POLE2 polymerase (DNA directed), epsilon 2, accessory subunit 0.0071232
TYROBP TYRO protein tyrosine kinase binding protein 0.00710984
MAGEA12 melanoma antigen family A12 0.00710686
DHCR24 24-dehydrocholesterol reductase 0.00708267
MNDA myeloid cell nuclear differentiation antigen 0.00707963
SLC25A15 solute carrier family 25 (mitochondrial carrier; ornithine transporter) member 15 0.00706718
GZMK granzyme K (granzyme 3; tryptase II) 0.00705341
STK38L serine/threonine kinase 38 like 0.00700572
CALR calreticulin 0.00697702
SRD5A1 steroid-5-alpha-reductase, alpha polypeptide 1 (3-oxo-5 alpha-steroid delta 4-dehydrogenase alpha 1) 0.00694997
PF4 platelet factor 4 0.00692956
OTULINL OTU deubiquitinase with linear linkage specificity like 0.00692751
PPBP pro-platelet basic protein (chemokine (C-X-C motif) ligand 7) 0.00692749
P2RY13 purinergic receptor P2Y, G-protein coupled, 13 0.00686811
C1QA complement component 1, q subcomponent, A chain 0.00686241
LGALS13 lectin, galactoside-binding, soluble, 13 0.00684418
TGIF1 TGFB-induced factor homeobox 1 0.00684267
NELL2 NEL-like 2 (chicken) 0.00675311
KLRB1 killer cell lectin-like receptor subfamily B, member 1 0.00672052
TMEM14A transmembrane protein 14A 0.00668096
DCK deoxycytidine kinase 0.00667189
QDPR quinoid dihydropteridine reductase 0.00663435
MICAL2 microtubule associated monooxygenase, calponin and LIM domain containing 2 0.00663149
GOLIM4 golgi integral membrane protein 4 0.00662697
SERPINE2 serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 2 0.0066102
RAPSN receptor-associated protein of the synapse 0.00658276
PIP prolactin-induced protein 0.00655909
PTPRN2 protein tyrosine phosphatase, receptor type, N polypeptide 2 0.00654009
FCGBP Fc fragment of IgG binding protein 0.00649516
SKP2 S-phase kinase-associated protein 2, E3 ubiquitin protein ligase 0.00647097
SSX2IP synovial sarcoma, X breakpoint 2 interacting protein 0.00646715
RIMS3 regulating synaptic membrane exocytosis 3 0.00645992
GPD1L glycerol-3-phosphate dehydrogenase 1-like 0.00645384
GSTA4 glutathione S-transferase alpha 4 0.00644097
DLEU1 deleted in lymphocytic leukemia 1 (non-protein coding) 0.00639178
SULF1 sulfatase 1 0.00638708
LRP4 low density lipoprotein receptor-related protein 4 0.00638287
TGFBI transforming growth factor, beta-induced, 68kDa 0.00638124
AGR2 anterior gradient 2 0.00635131
MS4A6A membrane-spanning 4-domains, subfamily A, member 6A 0.00634738
SPOCK1 sparc/osteonectin, cwcv and kazal-like domains proteoglycan (testican) 1 0.00634139
CD177 CD177 molecule 0.00631762
BMI1 BMI1 proto-oncogene, polycomb ring finger 0.00630471
LINC00339 long intergenic non-protein coding RNA 339 0.00627842
HDC histidine decarboxylase 0.00626666
LANCL1 LanC lantibiotic synthetase component C-like 1 (bacterial) 0.00626009
MCTP2 multiple C2 domains, transmembrane 2 0.00625296
IRF2 interferon regulatory factor 2 0.00624897
GOLPH3L golgi phosphoprotein 3-like 0.00624491
SERPINF1 serpin peptidase inhibitor, clade F (alpha-2 antiplasmin, pigment epithelium derived factor), member 1 0.00623411
AKR1C3 aldo-keto reductase family 1, member C3 0.00622415
NEFH neurofilament, heavy polypeptide 0.00621924
KLRK1 killer cell lectin-like receptor subfamily K, member 1 0.00621549
NKG7 natural killer cell granule protein 7 0.00620874
CD3E CD3e molecule, epsilon (CD3-TCR complex) 0.00619342
HSD17B6 hydroxysteroid (17-beta) dehydrogenase 6 0.00618427
IGSF6 immunoglobulin superfamily, member 6 0.00617694
TRPS1 trichorhinophalangeal syndrome I 0.00616793
GALNT1 polypeptide N-acetylgalactosaminyltransferase 1 0.00615196
SDHAF3 succinate dehydrogenase complex assembly factor 3 0.00614652
OIP5 Opa interacting protein 5 0.00613034
LCK LCK proto-oncogene, Src family tyrosine kinase 0.0061294
NID2 nidogen 2 (osteonidogen) 0.00610195
BRIX1 BRX1, biogenesis of ribosomes 0.00609814
VEGFA vascular endothelial growth factor A 0.00608281
GNG10 guanine nucleotide binding protein (G protein), gamma 10 0.00607966
CLEC7A C-type lectin domain family 7, member A 0.00607459
FUT8 fucosyltransferase 8 (alpha (1,6) fucosyltransferase) 0.00607456
ENO2 enolase 2 (gamma, neuronal) 0.00606965
WWOX WW domain containing oxidoreductase 0.00606964
RTN1 reticulon 1 0.00604315
CD46 CD46 molecule, complement regulatory protein 0.00603767
ZAP70 zeta-chain (TCR) associated protein kinase 70kDa 0.00603561
FRAT2 frequently rearranged in advanced T-cell lymphomas 2 0.00600616
CCR1 chemokine (C-C motif) receptor 1 0.00597883
TMEM164 transmembrane protein 164 0.0059782
ALDH3A1 aldehyde dehydrogenase 3 family, member A1 0.00595718
ARPP19 cAMP-regulated phosphoprotein, 19kDa 0.00593364
NSMCE4A non-SMC element 4 homolog A (S. cerevisiae) 0.00588961
MAOA monoamine oxidase A 0.00584638
GNAQ guanine nucleotide binding protein (G protein), q polypeptide 0.00584009
XAF1 XIAP associated factor 1 0.00583055
SERPINI1 serpin peptidase inhibitor, clade I (neuroserpin), member 1 0.00582824
GATA2 GATA binding protein 2 0.0058115
MRPS30 mitochondrial ribosomal protein S30 0.0058085
LCP2 lymphocyte cytosolic protein 2 (SH2 domain containing leukocyte protein of 76kDa) 0.00580551
HS3ST3A1 heparan sulfate (glucosamine) 3-O-sulfotransferase 3A1 0.00580185
MPP1 membrane protein, palmitoylated 1, 55kDa 0.00579939
ACACA acetyl-CoA carboxylase alpha 0.00578372
ANP32E acidic (leucine-rich) nuclear phosphoprotein 32 family, member E 0.00577799
TRIP13 thyroid hormone receptor interactor 13 0.0057685
FXYD3 FXYD domain containing ion transport regulator 3 0.00576141
CXCL14 chemokine (C-X-C motif) ligand 14 0.00575619
SECISBP2L SECIS binding protein 2-like 0.00574955
PRKAR2B protein kinase, cAMP-dependent, regulatory, type II, beta 0.00574303
RBL2 retinoblastoma-like 2 0.00571544
VRK1 vaccinia related kinase 1 0.0057063
PDE4D phosphodiesterase 4D, cAMP-specific 0.00569844
PLS3 plastin 3 0.00569791
ANP32A acidic (leucine-rich) nuclear phosphoprotein 32 family, member A 0.0056924
SLC16A1 solute carrier family 16 (monocarboxylate transporter), member 1 0.00568648
CEMIP cell migration inducing protein, hyaluronan binding 0.00567822
MCM6 minichromosome maintenance complex component 6 0.00567636
DPYD dihydropyrimidine dehydrogenase 0.00566594
PRR5 proline rich 5 (renal) 0.0056643
SPINT2 serine peptidase inhibitor, Kunitz type, 2 0.0056627
SIPA1L1 signal-induced proliferation-associated 1 like 1 0.00565796
CEP170 centrosomal protein 170kDa 0.00565557
HCLS1 hematopoietic cell-specific Lyn substrate 1 0.00562914
CDC20 cell division cycle 20 0.0056236
TCF12 transcription factor 12 0.00560157
HS2ST1 heparan sulfate 2-O-sulfotransferase 1 0.00558775
IL18RAP interleukin 18 receptor accessory protein 0.00558559
AMD1 adenosylmethionine decarboxylase 1 0.00558125
ITM2A integral membrane protein 2A 0.00557682
IDO1 indoleamine 2,3-dioxygenase 1 0.0055691
TSPO translocator protein (18kDa) 0.00556776
RAD51AP1 RAD51 associated protein 1 0.00556062
HLA-DRA major histocompatibility complex, class II, DR alpha 0.00554081
DHDDS dehydrodolichyl diphosphate synthase 0.00553931
PPP3CA protein phosphatase 3, catalytic subunit, alpha isozyme 0.00553241
CD247 CD247 molecule 0.00552573
GALNT10 polypeptide N-acetylgalactosaminyltransferase 10 0.0055218
ANOS1 anosmin 1 0.00550892
ODAM odontogenic, ameloblast asssociated 0.00550593
SCD stearoyl-CoA desaturase (delta-9-desaturase) 0.00550568
GPRC5A G protein-coupled receptor, class C, group 5, member A 0.00550107
PLBD1 phospholipase B domain containing 1 0.00549936
CD96 CD96 molecule 0.00549275
GPATCH8 G patch domain containing 8 0.00548904
G3BP1 GTPase activating protein (SH3 domain) binding protein 1 0.005473
TNFAIP6 tumor necrosis factor, alpha-induced protein 6 0.00547245
BCL11B B-cell CLL/lymphoma 11B (zinc finger protein) 0.00545712
KIT v-kit Hardy-Zuckerman 4 feline sarcoma viral oncogene homolog 0.00544801
CDK19 cyclin-dependent kinase 19 0.00543022
SF3A2 splicing factor 3a, subunit 2, 66kDa 0.00541457
CCR2 chemokine (C-C motif) receptor 2 0.00540456
SLC38A6 solute carrier family 38, member 6 0.00540103
LSM5 LSM5 homolog, U6 small nuclear RNA associated (S. cerevisiae) 0.00539785
NPM3 nucleophosmin/nucleoplasmin 3 0.0053978
SNRNP40 small nuclear ribonucleoprotein 40kDa (U5) 0.00538005
MYL1 myosin, light chain 1, alkali; skeletal, fast 0.00537186
LXN latexin 0.00536696
RPA3 replication protein A3, 14kDa 0.00536098
IRF4 interferon regulatory factor 4 0.00535995
DPM3 dolichyl-phosphate mannosyltransferase polypeptide 3 0.0053511

decreased expression

Symbol Name Standardized Value
RPS4Y1 ribosomal protein S4, Y-linked 1 -0.0220869
TACSTD2 tumor-associated calcium signal transducer 2 -0.0180025
DEFB1 defensin, beta 1 -0.0176288
SCGB1D2 secretoglobin, family 1D, member 2 -0.0175255
SCGB2A1 secretoglobin, family 2A, member 1 -0.0158117
MEF2C myocyte enhancer factor 2C -0.0150575
VNN1 vanin 1 -0.0136635
SPINK1 serine peptidase inhibitor, Kazal type 1 -0.0134246
GNAS GNAS complex locus -0.0132186
KLF6 Kruppel-like factor 6 -0.0128328
PDZK1IP1 PDZK1 interacting protein 1 -0.0127029
HSPA1A heat shock 70kDa protein 1A -0.0126311
WASHC4 WASH complex subunit 4 -0.0124751
CLDN10 claudin 10 -0.0121753
RFTN1 raftlin, lipid raft linker 1 -0.0120925
ASRGL1 asparaginase like 1 -0.0116731
CRABP2 cellular retinoic acid binding protein 2 -0.0115604
NPTX2 neuronal pentraxin II -0.0114749
MUC16 mucin 16, cell surface associated -0.0114194
EIF1AY eukaryotic translation initiation factor 1A, Y-linked -0.0113508
IER5 immediate early response 5 -0.0111836
PEG3 paternally expressed 3 -0.0109443
ATF3 activating transcription factor 3 -0.0107363
L1CAM L1 cell adhesion molecule -0.0104656
SPINK2 serine peptidase inhibitor, Kazal type 2 (acrosin-trypsin inhibitor) -0.010454
KLK10 kallikrein-related peptidase 10 -0.0104263
HOPX HOP homeobox -0.0103392
KDM5D lysine (K)-specific demethylase 5D -0.0100989
SGK1 serum/glucocorticoid regulated kinase 1 -0.0100092
NFKBIE nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, epsilon -0.00995227
PELI1 pellino E3 ubiquitin protein ligase 1 -0.00985412
SST somatostatin -0.00984065
INAVA innate immunity activator -0.00976739
MEIS1 Meis homeobox 1 -0.00975977
FILIP1L filamin A interacting protein 1-like -0.00971926
KLK5 kallikrein-related peptidase 5 -0.00956826
THBS2 thrombospondin 2 -0.00955144
PEG10 paternally expressed 10 -0.00952954
ENPEP glutamyl aminopeptidase (aminopeptidase A) -0.00945113
SERPINB2 serpin peptidase inhibitor, clade B (ovalbumin), member 2 -0.00944175
EEF1A2 eukaryotic translation elongation factor 1 alpha 2 -0.00943705
SCGB2A2 secretoglobin, family 2A, member 2 -0.0091945
MGLL monoglyceride lipase -0.00915183
ANGPT2 angiopoietin 2 -0.00900038
CA2 carbonic anhydrase II -0.00899089
CTSA cathepsin A -0.0089527
STK10 serine/threonine kinase 10 -0.00885892
GRB14 growth factor receptor-bound protein 14 -0.00884459
GULP1 GULP, engulfment adaptor PTB domain containing 1 -0.00871909
PEA15 phosphoprotein enriched in astrocytes 15 -0.00867631
ZFPM2 zinc finger protein, FOG family member 2 -0.00865332
CDKN1A cyclin-dependent kinase inhibitor 1A (p21, Cip1) -0.00863842
TNNT1 troponin T type 1 (skeletal, slow) -0.00855543
TFPI2 tissue factor pathway inhibitor 2 -0.00852078
SPON1 spondin 1, extracellular matrix protein -0.00849708
OGN osteoglycin -0.00839356
KRT23 keratin 23, type I -0.00826448
KLK7 kallikrein-related peptidase 7 -0.00824819
CYB5R2 cytochrome b5 reductase 2 -0.00823342
S100A7 S100 calcium binding protein A7 -0.00815599
MDK midkine (neurite growth-promoting factor 2) -0.00812014
RASGRP3 RAS guanyl releasing protein 3 (calcium and DAG-regulated) -0.00810596
AMOTL2 angiomotin like 2 -0.00795794
SMAD3 SMAD family member 3 -0.00794921
KRT19 keratin 19, type I -0.00794141
CHAC1 ChaC glutathione-specific gamma-glutamylcyclotransferase 1 -0.00794061
AHNAK AHNAK nucleoprotein -0.00792902
GATM glycine amidinotransferase (L-arginine:glycine amidinotransferase) -0.00786141
REEP1 receptor accessory protein 1 -0.00781634
PTN pleiotrophin -0.00781186
MCL1 myeloid cell leukemia 1 -0.00770458
AREG amphiregulin -0.0076935
BAG3 BCL2-associated athanogene 3 -0.00768528
KLK8 kallikrein-related peptidase 8 -0.00762146
EFNA1 ephrin-A1 -0.00760867
LYPD1 LY6/PLAUR domain containing 1 -0.0076077
DDX3Y DEAD (Asp-Glu-Ala-Asp) box helicase 3, Y-linked -0.00759749
VTCN1 V-set domain containing T cell activation inhibitor 1 -0.00759433
ARID4A AT rich interactive domain 4A (RBP1-like) -0.00757
ETFB electron-transfer-flavoprotein, beta polypeptide -0.00756392
CRP C-reactive protein, pentraxin-related -0.00755819
BBOX1 butyrobetaine (gamma), 2-oxoglutarate dioxygenase (gamma-butyrobetaine hydroxylase) 1 -0.00753528
OXA1L oxidase (cytochrome c) assembly 1-like -0.00750645
ARMCX3 armadillo repeat containing, X-linked 3 -0.0074336
KHDRBS3 KH domain containing, RNA binding, signal transduction associated 3 -0.00743186
C14ORF105 chromosome 14 open reading frame 105 -0.00742742
TFAP2C transcription factor AP-2 gamma (activating enhancer binding protein 2 gamma) -0.00732909
F2RL1 coagulation factor II (thrombin) receptor-like 1 -0.007308
JPT1 Jupiter microtubule associated homolog 1 -0.00729311
TUBB2A tubulin, beta 2A class IIa -0.00720563
ANO1 anoctamin 1, calcium activated chloride channel -0.00720519
KCTD12 potassium channel tetramerization domain containing 12 -0.00717155
LMO2 LIM domain only 2 (rhombotin-like 1) -0.00716982
FMO1 flavin containing monooxygenase 1 -0.00716081
DAXX death-domain associated protein -0.00714213
SGCE sarcoglycan, epsilon -0.0071327
GOT1 glutamic-oxaloacetic transaminase 1, soluble -0.00712264
G0S2 G0/G1 switch 2 -0.00708451
PPP1R16B protein phosphatase 1, regulatory subunit 16B -0.00702299
EMX2 empty spiracles homeobox 2 -0.00698683
PAPSS2 3'-phosphoadenosine 5'-phosphosulfate synthase 2 -0.00698679
RAB11FIP1 RAB11 family interacting protein 1 (class I) -0.00697461
GADD45A growth arrest and DNA-damage-inducible, alpha -0.00696976
ALDH3B2 aldehyde dehydrogenase 3 family, member B2 -0.00694316
WT1 Wilms tumor 1 -0.00694179
FXYD2 FXYD domain containing ion transport regulator 2 -0.00693379
WLS wntless Wnt ligand secretion mediator -0.00693068
CHST15 carbohydrate (N-acetylgalactosamine 4-sulfate 6-O) sulfotransferase 15 -0.0069296
RIPK4 receptor-interacting serine-threonine kinase 4 -0.00691556
ISG15 ISG15 ubiquitin-like modifier -0.00691191
LAT2 linker for activation of T cells family, member 2 -0.00690585
S100A2 S100 calcium binding protein A2 -0.00689813
NT5E 5'-nucleotidase, ecto (CD73) -0.00688366
ZMAT3 zinc finger, matrin-type 3 -0.00686705
FOLR1 folate receptor 1 (adult) -0.0068573
PPIF peptidylprolyl isomerase F -0.00685672
MOAP1 modulator of apoptosis 1 -0.00685536
TNFRSF10B tumor necrosis factor receptor superfamily, member 10b -0.00685468
ZNF83 zinc finger protein 83 -0.00683056
USP9Y ubiquitin specific peptidase 9, Y-linked -0.00682049
IFI16 interferon, gamma-inducible protein 16 -0.00681174
IFI44 interferon-induced protein 44 -0.00671013
HOXD1 homeobox D1 -0.00670012
RAI2 retinoic acid induced 2 -0.00668736
KLK11 kallikrein-related peptidase 11 -0.0066499
NEU1 sialidase 1 (lysosomal sialidase) -0.00663372
EEF1D eukaryotic translation elongation factor 1 delta (guanine nucleotide exchange protein) -0.00662216
SLC34A2 solute carrier family 34 (type II sodium/phosphate cotransporter), member 2 -0.00661526
C3 complement component 3 -0.00658716
RGCC regulator of cell cycle -0.00652168
ALDOB aldolase B, fructose-bisphosphate -0.00651924
PAEP progestagen-associated endometrial protein -0.00650264
ARHGAP29 Rho GTPase activating protein 29 -0.0064995
CARD10 caspase recruitment domain family, member 10 -0.00649386
PPP2R3A protein phosphatase 2, regulatory subunit B'', alpha -0.00647373
PDGFD platelet derived growth factor D -0.0064668
DDX21 DEAD (Asp-Glu-Ala-Asp) box helicase 21 -0.0064558
RAMP1 receptor (G protein-coupled) activity modifying protein 1 -0.00642629
RHCG Rh family, C glycoprotein -0.00641439
MRPL18 mitochondrial ribosomal protein L18 -0.00640483
HSPA6 heat shock 70kDa protein 6 (HSP70B') -0.00640236
SERPINA5 serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 5 -0.0063834
GALNT6 polypeptide N-acetylgalactosaminyltransferase 6 -0.00637564
MPZL2 myelin protein zero-like 2 -0.00637033
ELK3 ELK3, ETS-domain protein (SRF accessory protein 2) -0.00635986
YTHDF1 YTH N(6)-methyladenosine RNA binding protein 1 -0.00634594
HSP90AB1 heat shock protein 90kDa alpha (cytosolic), class B member 1 -0.00634455
GRAMD1C GRAM domain containing 1C -0.0063438
GPR137B G protein-coupled receptor 137B -0.00633011
C6ORF48 chromosome 6 open reading frame 48 -0.00633002
WDR91 WD repeat domain 91 -0.00631985
GSTA1 glutathione S-transferase alpha 1 -0.00631093
HTR2B 5-hydroxytryptamine (serotonin) receptor 2B, G protein-coupled -0.00630357
HSPB8 heat shock 22kDa protein 8 -0.00622414
EGR3 early growth response 3 -0.006223
CPE carboxypeptidase E -0.00621159
CD40 CD40 molecule, TNF receptor superfamily member 5 -0.00620544
CRYAB crystallin, alpha B -0.00618406
U2AF1 U2 small nuclear RNA auxiliary factor 1 -0.00617407
CDH16 cadherin 16, KSP-cadherin -0.00617156
EPS8L1 EPS8-like 1 -0.00615452
CLDN7 claudin 7 -0.00615362
TSC22D2 TSC22 domain family, member 2 -0.00615283
GPRC5B G protein-coupled receptor, class C, group 5, member B -0.00613719
CD99 CD99 molecule -0.00612738
DDX11 DEAD/H (Asp-Glu-Ala-Asp/His) box helicase 11 -0.00608684
ALB albumin -0.00607661
GOLM1 golgi membrane protein 1 -0.00606768
CRYBG1 crystallin beta-gamma domain containing 1 -0.00604877
IER2 immediate early response 2 -0.00603551
FBXW7 F-box and WD repeat domain containing 7, E3 ubiquitin protein ligase -0.00601773
NEFM neurofilament, medium polypeptide -0.00600942
SERPINA3 serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 3 -0.00600817
SPON2 spondin 2, extracellular matrix protein -0.00600543
ESM1 endothelial cell-specific molecule 1 -0.00599393
NR2F2 nuclear receptor subfamily 2, group F, member 2 -0.00598837
ECM1 extracellular matrix protein 1 -0.00597935
EGFL6 EGF-like-domain, multiple 6 -0.00597539
AHR aryl hydrocarbon receptor -0.00596463
KRT17 keratin 17, type I -0.00596136
RBKS ribokinase -0.00595723
SLC38A2 solute carrier family 38, member 2 -0.00595658
CD200 CD200 molecule -0.00595408
ITGA6 integrin, alpha 6 -0.0059429
ST14 suppression of tumorigenicity 14 (colon carcinoma) -0.00593435
ACTG2 actin, gamma 2, smooth muscle, enteric -0.00591198
HMOX1 heme oxygenase 1 -0.0058956
PMAIP1 phorbol-12-myristate-13-acetate-induced protein 1 -0.00589368
NXN nucleoredoxin -0.00588701
TMEM51 transmembrane protein 51 -0.00588533
WWC1 WW and C2 domain containing 1 -0.00587602
DNAJA1 DnaJ (Hsp40) homolog, subfamily A, member 1 -0.00585604
RARRES2 retinoic acid receptor responder (tazarotene induced) 2 -0.00585558
LGALS3 lectin, galactoside-binding, soluble, 3 -0.00584789
IGF1 insulin-like growth factor 1 (somatomedin C) -0.00584114
CTSD cathepsin D -0.00583514
NES nestin -0.00583172
NPIPB3 nuclear pore complex interacting protein family, member B3 -0.00581457
GPX3 glutathione peroxidase 3 -0.00581066
EIF6 eukaryotic translation initiation factor 6 -0.00579869
PLA1A phospholipase A1 member A -0.00579827
MVP major vault protein -0.00579426
ATP6V1B1 ATPase, H+ transporting, lysosomal 56/58kDa, V1 subunit B1 -0.00579243
KCNJ16 potassium channel, inwardly rectifying subfamily J, member 16 -0.00579196
FABP3 fatty acid binding protein 3, muscle and heart -0.00579185
NPR1 natriuretic peptide receptor 1 -0.00578474
ESR1 estrogen receptor 1 -0.00577742
MX1 MX dynamin-like GTPase 1 -0.00577124
IFITM3 interferon induced transmembrane protein 3 -0.0057274
TBX2 T-box 2 -0.00568212
NCAM1 neural cell adhesion molecule 1 -0.00568057
MITF microphthalmia-associated transcription factor -0.0056653
FLRT2 fibronectin leucine rich transmembrane protein 2 -0.00565723
TNFRSF21 tumor necrosis factor receptor superfamily, member 21 -0.00565577
FGD6 FYVE, RhoGEF and PH domain containing 6 -0.00565575
OLFM1 olfactomedin 1 -0.00565378
ALDH8A1 aldehyde dehydrogenase 8 family, member A1 -0.00565302
PLK2 polo-like kinase 2 -0.00562642
VCP valosin containing protein -0.00561112
PTTG1IP pituitary tumor-transforming 1 interacting protein -0.00560926
SLC3A1 solute carrier family 3 (amino acid transporter heavy chain), member 1 -0.00560912
TNNI2 troponin I type 2 (skeletal, fast) -0.00559233
ABCB1 ATP-binding cassette, sub-family B (MDR/TAP), member 1 -0.00558035
IL6R interleukin 6 receptor -0.00557217
RASSF2 Ras association (RalGDS/AF-6) domain family member 2 -0.00556725
UPP1 uridine phosphorylase 1 -0.00555879
SC5D sterol-C5-desaturase -0.00555083
EIF3D eukaryotic translation initiation factor 3, subunit D -0.00553801
CDC42 cell division cycle 42 -0.00553582
TMED9 transmembrane emp24 protein transport domain containing 9 -0.00553212
PODXL podocalyxin-like -0.00552322
RBM5 RNA binding motif protein 5 -0.00552251
PUF60 poly-U binding splicing factor 60KDa -0.00547045
GRAMD2B GRAM domain containing 2B -0.00546156
STAG3 stromal antigen 3 -0.00545672
FGG fibrinogen gamma chain -0.00545578
BTG3 BTG family, member 3 -0.00545385
MYL2 myosin, light chain 2, regulatory, cardiac, slow -0.00544896
DOK5 docking protein 5 -0.00544768
PDLIM3 PDZ and LIM domain 3 -0.00544394
RIPK2 receptor-interacting serine-threonine kinase 2 -0.00543246
HAND2-AS1 HAND2 antisense RNA 1 (head to head) -0.00542656
PPP1R15A protein phosphatase 1, regulatory subunit 15A -0.00542485
CDH6 cadherin 6, type 2, K-cadherin (fetal kidney) -0.00542352
TUFT1 tuftelin 1 -0.00541308
RRAD Ras-related associated with diabetes -0.00541169
EDN1 endothelin 1 -0.00540603
SLC16A6 solute carrier family 16, member 6 -0.00540544
CDH13 cadherin 13 -0.00540472
RAP1GAP2 RAP1 GTPase activating protein 2 -0.00539659