SCRN2 Gene Set

Dataset CM4AI KOLF21J CRISPRi Gene Perturbation Atlas
Category transcriptomics
Type gene perturbation
Description secernin 2| (NCBI Entrez Gene Database, 90507)
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Genes

310 genes differentially expressed following the SCRN2 gene perturbation from the CM4AI KOLF21J CRISPRi Gene Perturbation Atlas.

increased expression

Symbol Name Standardized Value
OAS1 2'-5'-oligoadenylate synthetase 1, 40/46kDa 2.88138
TNFRSF6B tumor necrosis factor receptor superfamily, member 6b, decoy 2.88138
PCDHB7 protocadherin beta 7 2.88138
FOXA2 forkhead box A2 2.88138
HES5 hes family bHLH transcription factor 5 2.88138
OSGIN1 oxidative stress induced growth inhibitor 1 2.88138
TCHH trichohyalin 2.88138
GSX2 GS homeobox 2 2.88138
CLEC19A C-type lectin domain family 19, member A 2.88138
GJB1 gap junction protein, beta 1, 32kDa 2.88138
ENTHD1 ENTH domain containing 1 2.88138
OR5B12 olfactory receptor, family 5, subfamily B, member 12 2.88138
SLC26A4 solute carrier family 26 (anion exchanger), member 4 2.88138
ATP13A4 ATPase type 13A4 2.88138
ELAVL4 ELAV like neuron-specific RNA binding protein 4 2.88138
GPR4 G protein-coupled receptor 4 2.88138
NTRK1 neurotrophic tyrosine kinase, receptor, type 1 2.88138
SIX3 SIX homeobox 3 2.88138
COX4I2 cytochrome c oxidase subunit IV isoform 2 (lung) 2.88138
SELPLG selectin P ligand 2.88138
SLC5A1 solute carrier family 5 (sodium/glucose cotransporter), member 1 2.88138
AKR7L aldo-keto reductase family 7-like (gene/pseudogene) 2.88138
KCNJ1 potassium channel, inwardly rectifying subfamily J, member 1 2.88138
LYVE1 lymphatic vessel endothelial hyaluronan receptor 1 2.88138
LRG1 leucine-rich alpha-2-glycoprotein 1 2.88138
CELA1 chymotrypsin-like elastase family, member 1 2.88138
S100A5 S100 calcium binding protein A5 2.88138
LGR6 leucine-rich repeat containing G protein-coupled receptor 6 2.88138
NAA11 N(alpha)-acetyltransferase 11, NatA catalytic subunit 2.88138
B3GNT8 UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 8 2.88138
TSHZ1 teashirt zinc finger homeobox 1 2.88138
OVCH1 ovochymase 1 2.88138
HMX3 H6 family homeobox 3 2.88138
ABCA4 ATP-binding cassette, sub-family A (ABC1), member 4 2.88138
KCNE4 potassium channel, voltage gated subfamily E regulatory beta subunit 4 2.88138
ARRDC5 arrestin domain containing 5 2.88138
LCN12 lipocalin 12 2.88138
ASB14 ankyrin repeat and SOCS box containing 14 2.88138
SLC30A2 solute carrier family 30 (zinc transporter), member 2 2.88138
PHKG1 phosphorylase kinase, gamma 1 (muscle) 2.88138
CARTPT CART prepropeptide 2.88138
PBOV1 prostate and breast cancer overexpressed 1 2.88138
ADAD2 adenosine deaminase domain containing 2 2.88138
UNC45B unc-45 homolog B (C. elegans) 2.88138
NRROS negative regulator of reactive oxygen species 2.88138
MROH2B maestro heat-like repeat family member 2B 2.88138
STAP1 signal transducing adaptor family member 1 2.88138
GDA guanine deaminase 2.88138
OR5BS1 olfactory receptor family 5 subfamily BS member 1 2.88138
ELOVL3 ELOVL fatty acid elongase 3 2.88138
PAPOLB poly(A) polymerase beta (testis specific) 2.88138
TMEM40 transmembrane protein 40 2.88138
ASB5 ankyrin repeat and SOCS box containing 5 2.88138
SRPK3 SRSF protein kinase 3 2.88138
CFC1 cripto, FRL-1, cryptic family 1 2.88138
FAM228A family with sequence similarity 228, member A 2.88138
HTR3B 5-hydroxytryptamine (serotonin) receptor 3B, ionotropic 2.88138
GATA5 GATA binding protein 5 2.88138
BEND2 BEN domain containing 2 2.88138
ST6GALNAC1 ST6 (alpha-N-acetyl-neuraminyl-2,3-beta-galactosyl-1,3)-N-acetylgalactosaminide alpha-2,6-sialyltransferase 1 2.88138
DDC dopa decarboxylase (aromatic L-amino acid decarboxylase) 2.88138
TEX53 testis expressed 53 2.88138
THSD8 thrombospondin type 1 domain containing 8 2.88138
CPNE8-AS1 CPNE8 antisense RNA 1 2.88138
PRRT1B proline rich transmembrane protein 1B 2.88138
LOC124904411 uncharacterized LOC124904411 2.88138
H3C14 H3 clustered histone 14 2.88138
GARIN6 golgi associated RAB2 interactor family member 6 2.88138
CCDC190 coiled-coil domain containing 190 2.88138
DNAI7 dynein axonemal intermediate chain 7 2.88138
KL klotho 2.88138
CCDC42 coiled-coil domain containing 42 2.88138
CNTN6 contactin 6 2.88138
TOMM34 translocase of outer mitochondrial membrane 34 2.88138
HAPLN2 hyaluronan and proteoglycan link protein 2 2.88138
ANXA13 annexin A13 2.88138
CKM creatine kinase, muscle 2.88138
IL31RA interleukin 31 receptor A 2.88138
TRIM67 tripartite motif containing 67 2.88138
TRIM63 tripartite motif containing 63, E3 ubiquitin protein ligase 2.88138
SNX20 sorting nexin 20 2.88138
MAGEB3 melanoma antigen family B3 2.88138
TLR6 toll-like receptor 6 2.88138
TLR8 toll-like receptor 8 2.88138
SLAMF7 SLAM family member 7 2.88138
LTB lymphotoxin beta (TNF superfamily, member 3) 2.88138
ZNF683 zinc finger protein 683 2.88138
HIVEP1 human immunodeficiency virus type I enhancer binding protein 1 2.88138
ALG10B ALG10B, alpha-1,2-glucosyltransferase 2.88138
CCR3 chemokine (C-C motif) receptor 3 2.88138
EXOC3L1 exocyst complex component 3-like 1 2.88138
OR2L2 olfactory receptor, family 2, subfamily L, member 2 2.88138
C1QTNF9 C1q and tumor necrosis factor related protein 9 2.88138
SLC9A3 solute carrier family 9, subfamily A (NHE3, cation proton antiporter 3), member 3 2.88138
TUBA3E tubulin, alpha 3e 2.88138
CCDC89 coiled-coil domain containing 89 2.88138
PCDHGB5 protocadherin gamma subfamily B, 5 2.88138
MKRN3 makorin ring finger protein 3 2.88138
ERICH6B glutamate-rich 6B 2.88138
F2RL3 coagulation factor II (thrombin) receptor-like 3 2.88138
CPA5 carboxypeptidase A5 2.88138
CCDC27 coiled-coil domain containing 27 2.88138
CGB7 chorionic gonadotropin, beta polypeptide 7 2.88138
VWA3B von Willebrand factor A domain containing 3B 2.88138
VWA7 von Willebrand factor A domain containing 7 2.88138
P2RX2 purinergic receptor P2X, ligand gated ion channel, 2 2.88138
KLF1 Kruppel-like factor 1 (erythroid) 2.88138
S100Z S100 calcium binding protein Z 2.88138
CLRN2 clarin 2 2.88138
KRT3 keratin 3, type II 2.88138
GLYATL3 glycine-N-acyltransferase-like 3 2.88138
CCL27 chemokine (C-C motif) ligand 27 2.88138
NIM1K NIM1 serine/threonine protein kinase 2.88138
LCT lactase 2.88138
SV2C synaptic vesicle glycoprotein 2C 2.88138
SERPINB11 serpin peptidase inhibitor, clade B (ovalbumin), member 11 (gene/pseudogene) 2.88138
THTPA thiamine triphosphatase 2.88138
DEFB107B defensin, beta 107B 2.88138
C8ORF89 chromosome 8 open reading frame 89 2.88138
KLK15 kallikrein-related peptidase 15 2.88138
LY6G6D lymphocyte antigen 6 complex, locus G6D 2.88138
LDLRAD1 low density lipoprotein receptor class A domain containing 1 2.88138
RIIAD1 regulatory subunit of type II PKA R-subunit (RIIa) domain containing 1 2.88138
MYADML2 myeloid-associated differentiation marker-like 2 2.88138
LAMB4 laminin, beta 4 2.88138
C10ORF105 chromosome 10 open reading frame 105 2.88138
CXORF49C chromosome X open reading frame 49C 2.88138
PLA2G5 phospholipase A2, group V 2.88138
TTC22 tetratricopeptide repeat domain 22 2.88138
CSF1R colony stimulating factor 1 receptor 2.88138
LYZ lysozyme 2.88138
VAV1 vav 1 guanine nucleotide exchange factor 2.88138
KLK12 kallikrein-related peptidase 12 2.88138
COL6A5 collagen, type VI, alpha 5 2.88138
SST somatostatin 2.88138
KLK3 kallikrein-related peptidase 3 2.88138
CFAP47 cilia and flagella associated protein 47 2.88138
C8A complement component 8, alpha polypeptide 2.88138
ITGB7 integrin, beta 7 2.88138
SLC4A1 solute carrier family 4 (anion exchanger), member 1 (Diego blood group) 2.88138
SMIM17 small integral membrane protein 17 2.88138
C22ORF31 chromosome 22 open reading frame 31 2.88138
PRSS21 protease, serine, 21 (testisin) 2.88138
NLRP6 NLR family, pyrin domain containing 6 2.88138
AOC1 amine oxidase, copper containing 1 2.88138
PRSS57 protease, serine, 57 2.88138
MMP12 matrix metallopeptidase 12 2.88138
PTPN7 protein tyrosine phosphatase, non-receptor type 7 2.88138
ACSM5 acyl-CoA synthetase medium-chain family member 5 2.88138
DNAJC22 DnaJ (Hsp40) homolog, subfamily C, member 22 2.88138
CACNA2D4 calcium channel, voltage-dependent, alpha 2/delta subunit 4 2.88138
APOL4 apolipoprotein L, 4 2.88138
PATE2 prostate and testis expressed 2 2.88138
ASCL4 achaete-scute family bHLH transcription factor 4 2.88138
CIDEA cell death-inducing DFFA-like effector a 2.88138
DHRS9 dehydrogenase/reductase (SDR family) member 9 2.88138
G6PC2 glucose-6-phosphatase, catalytic, 2 2.88138
PLA2G4D phospholipase A2, group IVD (cytosolic) 2.88138
CEACAM16 carcinoembryonic antigen-related cell adhesion molecule 16 2.88138
PLA2G1B phospholipase A2, group IB (pancreas) 2.88138
GIT2 G protein-coupled receptor kinase interacting ArfGAP 2 2.88138
MS4A12 membrane-spanning 4-domains, subfamily A, member 12 2.88138
ADRA1B adrenoceptor alpha 1B 2.88138
R3HDML R3H domain containing-like 2.88138
LRRC63 leucine rich repeat containing 63 2.79064
C20ORF204 chromosome 20 open reading frame 204 2.79064
MEPE matrix extracellular phosphoglycoprotein 2.79064
F12 coagulation factor XII (Hageman factor) 2.69066
LAMA3 laminin, alpha 3 2.57406
ZBTB44 zinc finger and BTB domain containing 44 2.51778
CDR2L cerebellar degeneration-related protein 2-like 2.50992
OR6A2 olfactory receptor, family 6, subfamily A, member 2 2.50992
NUFIP2 nuclear fragile X mental retardation protein interacting protein 2 2.48124
CPPED1 calcineurin-like phosphoesterase domain containing 1 2.47474
RYK receptor-like tyrosine kinase 2.45837
MORC4 MORC family CW-type zinc finger 4 2.45624
ASCL1 achaete-scute family bHLH transcription factor 1 2.45624
NPAS1 neuronal PAS domain protein 1 2.44524
ZBED11 zinc finger BED-type containing 11 2.43391
VCX3A variable charge, X-linked 3A 2.40249
SPOP speckle-type POZ protein 2.3958
BIRC3 baculoviral IAP repeat containing 3 2.39094
ZNF385B zinc finger protein 385B 2.36915
PNPLA5 patatin-like phospholipase domain containing 5 2.36307
GOLM1 golgi membrane protein 1 2.36184
C6ORF120 chromosome 6 open reading frame 120 2.3335
LHFPL5 lipoma HMGIC fusion partner-like 5 2.31824
PCDHGA9 protocadherin gamma subfamily A, 9 2.31207
UPB1 ureidopropionase, beta 2.28175
TM2D1 TM2 domain containing 1 2.27652
B9D1 B9 protein domain 1 2.24719
LOC105378220 macrophage receptor MARCO-like 2.23877
RTL8B retrotransposon Gag like 8B 2.22
ZBTB33 zinc finger and BTB domain containing 33 2.22
GABRG3 gamma-aminobutyric acid (GABA) A receptor, gamma 3 2.22
GTF2H3 general transcription factor IIH, polypeptide 3, 34kDa 2.2118
HCLS1 hematopoietic cell-specific Lyn substrate 1 2.20094
RORC RAR-related orphan receptor C 2.20094
MYOCOS myocilin opposite strand 2.20094
STS steroid sulfatase (microsomal), isozyme S 2.19243
ZNF783 zinc finger family member 783 2.19243
AGAP5 ArfGAP with GTPase domain, ankyrin repeat and PH domain 5 2.18529
GREB1L growth regulation by estrogen in breast cancer-like 2.17015
RABL6 RAB, member RAS oncogene family-like 6 2.1391
IRF2BP1 interferon regulatory factor 2 binding protein 1 2.1391
QRICH1 glutamine-rich 1 2.1391
RUSF1 RUS family member 1 2.11757
MED8 mediator complex subunit 8 2.11681
ESRRA estrogen-related receptor alpha 2.08803
RAG1 recombination activating gene 1 2.06724
PDXDC1 pyridoxal-dependent decarboxylase domain containing 1 2.06168
TYK2 tyrosine kinase 2 2.06168
ATP6V1A ATPase, H+ transporting, lysosomal 70kDa, V1 subunit A 2.06168
CTHRC1 collagen triple helix repeat containing 1 2.05848
COX5B cytochrome c oxidase subunit Vb 2.04219
DDX11 DEAD/H (Asp-Glu-Ala-Asp/His) box helicase 11 2.04015
SENP6 SUMO1/sentrin specific peptidase 6 2.03319
MRS2 MRS2 magnesium transporter 2.03002
TRA2B transformer 2 beta homolog (Drosophila) 2.02081
MIER3 mesoderm induction early response 1, family member 3 2.02081
DNER delta/notch-like EGF repeat containing 2.00952

decreased expression

Symbol Name Standardized Value
BEND6 BEN domain containing 6 -2.88138
C11ORF87 chromosome 11 open reading frame 87 -2.88138
ABCG4 ATP-binding cassette, sub-family G (WHITE), member 4 -2.88138
NLRP10 NLR family, pyrin domain containing 10 -2.88138
SLC28A2 solute carrier family 28 (concentrative nucleoside transporter), member 2 -2.88138
DPPA3 developmental pluripotency associated 3 -2.88138
ITIH6 inter-alpha-trypsin inhibitor heavy chain family, member 6 -2.88138
ITIH2 inter-alpha-trypsin inhibitor heavy chain 2 -2.88138
IL17B interleukin 17B -2.88138
C17ORF100 chromosome 17 open reading frame 100 -2.88138
CSTL1 cystatin-like 1 -2.88138
OR2AG2 olfactory receptor, family 2, subfamily AG, member 2 -2.88138
SH2D6 SH2 domain containing 6 -2.88138
CLDN16 claudin 16 -2.88138
SH3TC2 SH3 domain and tetratricopeptide repeats 2 -2.88138
IFIT2 interferon-induced protein with tetratricopeptide repeats 2 -2.88138
RPS16 ribosomal protein S16 -2.88138
SYT15B synaptotagmin 15B -2.88138
ACOT1 acyl-CoA thioesterase 1 -2.88138
AJUBA ajuba LIM protein -2.88138
IZUMO3 IZUMO family member 3 -2.88138
PCDHB9 protocadherin beta 9 -2.88138
KCNH3 potassium channel, voltage gated eag related subfamily H, member 3 -2.88138
ZNF703 zinc finger protein 703 -2.88138
CNTF ciliary neurotrophic factor -2.88138
OAZ3 ornithine decarboxylase antizyme 3 -2.88138
ZCCHC12 zinc finger, CCHC domain containing 12 -2.88138
TMEM255A transmembrane protein 255A -2.88138
SCRN2 secernin 2 -2.88138
ARMC10 armadillo repeat containing 10 -2.88138
CBX8 chromobox homolog 8 -2.88138
ITGB3 integrin, beta 3 (platelet glycoprotein IIIa, antigen CD61) -2.88138
MYF6 myogenic factor 6 (herculin) -2.88138
ACRBP acrosin binding protein -2.79064
KIF25 kinesin family member 25 -2.77356
SCGB3A2 secretoglobin, family 3A, member 2 -2.77025
MND1 meiotic nuclear divisions 1 homolog (S. cerevisiae) -2.73443
HPS4 Hermansky-Pudlak syndrome 4 -2.70237
ZNF33B zinc finger protein 33B -2.60768
TGFB2 transforming growth factor, beta 2 -2.5962
KLHL22 kelch-like family member 22 -2.50992
PCDHGC3 protocadherin gamma subfamily C, 3 -2.48062
TULP2 tubby like protein 2 -2.48062
USP10 ubiquitin specific peptidase 10 -2.48062
MPPED1 metallophosphoesterase domain containing 1 -2.48062
DHX36 DEAH (Asp-Glu-Ala-His) box polypeptide 36 -2.48062
ASPG asparaginase -2.48062
ITSN2 intersectin 2 -2.46741
MFSD2A major facilitator superfamily domain containing 2A -2.45624
BCS1L BC1 (ubiquinol-cytochrome c reductase) synthesis-like -2.4509
DNA2 DNA replication helicase/nuclease 2 -2.44524
PABPC1 poly(A) binding protein, cytoplasmic 1 -2.44524
SENP1 SUMO1/sentrin specific peptidase 1 -2.3969
PIN4 peptidylprolyl cis/trans isomerase, NIMA-interacting 4 -2.3958
HSF1 heat shock transcription factor 1 -2.38892
LIPA lipase A, lysosomal acid, cholesterol esterase -2.36915
MGARP mitochondria-localized glutamic acid-rich protein -2.33652
DNAJB11 DnaJ (Hsp40) homolog, subfamily B, member 11 -2.33549
IL1RAPL2 interleukin 1 receptor accessory protein-like 2 -2.33158
UBOX5 U-box domain containing 5 -2.30102
SLC25A15 solute carrier family 25 (mitochondrial carrier; ornithine transporter) member 15 -2.29862
SNX11 sorting nexin 11 -2.27558
MIB2 mindbomb E3 ubiquitin protein ligase 2 -2.26669
ATP5MJ ATP synthase membrane subunit j -2.2605
LYST lysosomal trafficking regulator -2.23877
TEX11 testis expressed 11 -2.23877
ZNF174 zinc finger protein 174 -2.22
RPL23 ribosomal protein L23 -2.22
CA1 carbonic anhydrase I -2.22
PRPF4B pre-mRNA processing factor 4B -2.18048
FBXO16 F-box protein 16 -2.15153
MAP2K2 mitogen-activated protein kinase kinase 2 -2.15016
LMF1 lipase maturation factor 1 -2.1391
CIT citron rho-interacting serine/threonine kinase -2.13865
ANGPTL1 angiopoietin-like 1 -2.13865
PLAAT1 phospholipase A and acyltransferase 1 -2.08855
CD300A CD300a molecule -2.08345
CRYM crystallin, mu -2.08345
GPR158 G protein-coupled receptor 158 -2.07786
CEP20 centrosomal protein 20 -2.06724
GOLGA5 golgin A5 -2.06281
ZBTB5 zinc finger and BTB domain containing 5 -2.06281
ZNF641 zinc finger protein 641 -2.06041
KCND2 potassium channel, voltage gated Shal related subfamily D, member 2 -2.04982
DFFB DNA fragmentation factor, 40kDa, beta polypeptide (caspase-activated DNase) -2.04972
MRPL19 mitochondrial ribosomal protein L19 -2.03319
SHOC1 shortage in chiasmata 1 -2.03002
PTPMT1 protein tyrosine phosphatase, mitochondrial 1 -2.02081
SLC12A9 solute carrier family 12, member 9 -2.019