SCT Gene Set

Dataset Guide to Pharmacology Protein Ligands of Receptors
Category physical interactions
Type ligand (protein)
Description secretin|Secretin belongs to the glucagon family. This protein is an endocrine hormone and its major site of production is the endocrine S cells located in the proximal small intestinal mucosa. The release of active secretin is stimulated by either fatty acids or an acidic pH in the duodenum. This hormone stimulates the secretion of bicarbonate-rich pancreatic fluids and has also been shown to regulate the growth and development of the stomach, small intestine, and pancreas. Secretin deficiency has been implicated in autistic syndrome, suggesting that the hormone could have a neuroendocrine function in addition to its role in digestion. [provided by RefSeq, Jul 2008] (NCBI Entrez Gene Database, 6343)
External Link http://www.guidetopharmacology.org/GRAC/LigandDisplayForward?ligandId=6343
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Genes

4 receptors of the SCT ligand (protein) from the curated Guide to Pharmacology Protein Ligands of Receptors dataset.

Symbol Name
ADCYAP1R1 adenylate cyclase activating polypeptide 1 (pituitary) receptor type I
SCTR secretin receptor
VIPR1 vasoactive intestinal peptide receptor 1
VIPR2 vasoactive intestinal peptide receptor 2