SDHA Gene Set

Dataset Hub Proteins Protein-Protein Interactions
Category physical interactions
Type hub protein
Description succinate dehydrogenase complex, subunit A, flavoprotein (Fp)|This gene encodes a major catalytic subunit of succinate-ubiquinone oxidoreductase, a complex of the mitochondrial respiratory chain. The complex is composed of four nuclear-encoded subunits and is localized in the mitochondrial inner membrane. Mutations in this gene have been associated with a form of mitochondrial respiratory chain deficiency known as Leigh Syndrome. A pseudogene has been identified on chromosome 3q29. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jun 2014] (NCBI Entrez Gene Database, 6389)
External Link http://www.ncbi.nlm.nih.gov/gene/6389
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Genes

50 interacting proteins for hub protein SDHA from the curated Hub Proteins Protein-Protein Interactions dataset.

Symbol Name
ACADVL acyl-CoA dehydrogenase, very long chain
ALDOB aldolase B, fructose-bisphosphate
ARRB2 arrestin, beta 2
C19ORF53 chromosome 19 open reading frame 53
CD99L2 CD99 molecule-like 2
CLPB ClpB homolog, mitochondrial AAA ATPase chaperonin
CLPX caseinolytic mitochondrial matrix peptidase chaperone subunit
COPA coatomer protein complex, subunit alpha
CSF2RA colony stimulating factor 2 receptor, alpha, low-affinity (granulocyte-macrophage)
DLD dihydrolipoamide dehydrogenase
DLG4 discs, large homolog 4 (Drosophila)
DNMT3A DNA (cytosine-5-)-methyltransferase 3 alpha
FADD Fas (TNFRSF6)-associated via death domain
GABARAP GABA(A) receptor-associated protein
GABARAPL1 GABA(A) receptor-associated protein like 1
GABARAPL2 GABA(A) receptor-associated protein-like 2
GMCL1 germ cell-less, spermatogenesis associated 1
GRHPR glyoxylate reductase/hydroxypyruvate reductase
GRN granulin
HMGB1 high mobility group box 1
HMGCS1 3-hydroxy-3-methylglutaryl-CoA synthase 1 (soluble)
IKBKE inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase epsilon
MAP1LC3A microtubule-associated protein 1 light chain 3 alpha
MCM3AP minichromosome maintenance complex component 3 associated protein
MED6 mediator complex subunit 6
MRI1 methylthioribose-1-phosphate isomerase 1
NBAS neuroblastoma amplified sequence
NGFRAP1 nerve growth factor receptor (TNFRSF16) associated protein 1
PAPD4 PAP associated domain containing 4
PLA2G4B phospholipase A2, group IVB (cytosolic)
POLB polymerase (DNA directed), beta
PRPF18 pre-mRNA processing factor 18
RUNX3 runt-related transcription factor 3
SDHB succinate dehydrogenase complex, subunit B, iron sulfur (Ip)
SDHC succinate dehydrogenase complex, subunit C, integral membrane protein, 15kDa
SDHD succinate dehydrogenase complex, subunit D, integral membrane protein
SELPLG selectin P ligand
SERPINA2 serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 2 (gene/pseudogene)
SIKE1 suppressor of IKBKE 1
SLC2A4 solute carrier family 2 (facilitated glucose transporter), member 4
SLC9B2 solute carrier family 9, subfamily B (NHA2, cation proton antiporter 2), member 2
SPEG SPEG complex locus
SRRM2 serine/arginine repetitive matrix 2
STC1 stanniocalcin 1
SYNE1 spectrin repeat containing, nuclear envelope 1
TESC tescalcin
TRG T cell receptor gamma locus
UBXN4 UBX domain protein 4
VPS29 vacuolar protein sorting 29 homolog (S. cerevisiae)
ZBED5 zinc finger, BED-type containing 5