| Dataset | LINCS L1000 CMAP CRISPR Knockout Consensus Signatures |
| Category | transcriptomics |
| Type | gene perturbation |
| Description | succinate dehydrogenase complex, subunit D, integral membrane protein|This gene encodes a member of complex II of the respiratory chain, which is responsible for the oxidation of succinate. The encoded protein is one of two integral membrane proteins anchoring the complex to the matrix side of the mitochondrial inner membrane. Mutations in this gene are associated with the formation of tumors, including hereditary paraganglioma. Transmission of disease occurs almost exclusively through the paternal allele, suggesting that this locus may be maternally imprinted. There are pseudogenes for this gene on chromosomes 1, 2, 3, 7, and 18. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Feb 2013] (NCBI Entrez Gene Database, 6392) |
| External Link | https://ncbi.nlm.nih.gov/gene/6392 |
| Similar Terms | |
| Downloads & Tools |
498 genes differentially expressed following the SDHD gene perturbation from the LINCS L1000 CMAP CRISPR Knockout Consensus Signatures dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| LSM5 | LSM5 homolog, U6 small nuclear RNA associated (S. cerevisiae) | 0.0180469 |
| DNAJA3 | DnaJ (Hsp40) homolog, subfamily A, member 3 | 0.0166048 |
| RPS4Y1 | ribosomal protein S4, Y-linked 1 | 0.0160737 |
| AMIGO2 | adhesion molecule with Ig-like domain 2 | 0.013439 |
| G0S2 | G0/G1 switch 2 | 0.0111835 |
| ZNF589 | zinc finger protein 589 | 0.0108291 |
| LTBP2 | latent transforming growth factor beta binding protein 2 | 0.0102909 |
| EIF1AY | eukaryotic translation initiation factor 1A, Y-linked | 0.0102805 |
| SIRT3 | sirtuin 3 | 0.00999511 |
| ESR1 | estrogen receptor 1 | 0.00998112 |
| CLEC11A | C-type lectin domain family 11, member A | 0.00990492 |
| BST2 | bone marrow stromal cell antigen 2 | 0.00979265 |
| MET | MET proto-oncogene, receptor tyrosine kinase | 0.00977527 |
| ABHD4 | abhydrolase domain containing 4 | 0.00968966 |
| CD93 | CD93 molecule | 0.00966671 |
| IRF7 | interferon regulatory factor 7 | 0.00958915 |
| DPYSL3 | dihydropyrimidinase-like 3 | 0.00947816 |
| TNS3 | tensin 3 | 0.00937029 |
| AGR2 | anterior gradient 2 | 0.00914238 |
| NFKBIE | nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, epsilon | 0.00890223 |
| VWF | von Willebrand factor | 0.00886729 |
| HSPA1A | heat shock 70kDa protein 1A | 0.00863829 |
| TMEM204 | transmembrane protein 204 | 0.00857523 |
| ACTN1 | actinin, alpha 1 | 0.008575 |
| CCL19 | chemokine (C-C motif) ligand 19 | 0.00855112 |
| ID1 | inhibitor of DNA binding 1, dominant negative helix-loop-helix protein | 0.00851861 |
| OAS3 | 2'-5'-oligoadenylate synthetase 3, 100kDa | 0.00842128 |
| LAMP5 | lysosomal-associated membrane protein family, member 5 | 0.00834928 |
| SRC | SRC proto-oncogene, non-receptor tyrosine kinase | 0.00834901 |
| SNAP25 | synaptosomal-associated protein, 25kDa | 0.00831576 |
| EEF1A2 | eukaryotic translation elongation factor 1 alpha 2 | 0.00830346 |
| ELAPOR1 | endosome-lysosome associated apoptosis and autophagy regulator 1 | 0.00823725 |
| PLIN2 | perilipin 2 | 0.00814092 |
| HNRNPM | heterogeneous nuclear ribonucleoprotein M | 0.00808762 |
| FABP4 | fatty acid binding protein 4, adipocyte | 0.00801387 |
| KDM5D | lysine (K)-specific demethylase 5D | 0.00799701 |
| PPARG | peroxisome proliferator-activated receptor gamma | 0.00793868 |
| TIMP1 | TIMP metallopeptidase inhibitor 1 | 0.00793271 |
| MGLL | monoglyceride lipase | 0.00792975 |
| RABEP2 | rabaptin, RAB GTPase binding effector protein 2 | 0.00791474 |
| IFI44L | interferon-induced protein 44-like | 0.00782671 |
| MPRIP | myosin phosphatase Rho interacting protein | 0.00781498 |
| AHR | aryl hydrocarbon receptor | 0.00778883 |
| SRGN | serglycin | 0.00775928 |
| IRS1 | insulin receptor substrate 1 | 0.0077026 |
| TBC1D9B | TBC1 domain family, member 9B (with GRAM domain) | 0.00764003 |
| AGRN | agrin | 0.00763844 |
| GGCT | gamma-glutamylcyclotransferase | 0.00762745 |
| HSD11B1 | hydroxysteroid (11-beta) dehydrogenase 1 | 0.00761755 |
| QPCT | glutaminyl-peptide cyclotransferase | 0.00759483 |
| GZMB | granzyme B (granzyme 2, cytotoxic T-lymphocyte-associated serine esterase 1) | 0.00758505 |
| GSTP1 | glutathione S-transferase pi 1 | 0.00757508 |
| GUSBP3 | glucuronidase, beta pseudogene 3 | 0.00756037 |
| DUSP7 | dual specificity phosphatase 7 | 0.00748413 |
| TGFBI | transforming growth factor, beta-induced, 68kDa | 0.00746009 |
| PFDN4 | prefoldin subunit 4 | 0.00743452 |
| SCUBE2 | signal peptide, CUB domain, EGF-like 2 | 0.00741771 |
| USP22 | ubiquitin specific peptidase 22 | 0.00740564 |
| ZCCHC24 | zinc finger, CCHC domain containing 24 | 0.00739252 |
| RPS6KA2 | ribosomal protein S6 kinase, 90kDa, polypeptide 2 | 0.0073569 |
| BASP1 | brain abundant, membrane attached signal protein 1 | 0.00731822 |
| LYZ | lysozyme | 0.00731085 |
| COL3A1 | collagen, type III, alpha 1 | 0.00726994 |
| ACADVL | acyl-CoA dehydrogenase, very long chain | 0.00726874 |
| CST3 | cystatin C | 0.0072223 |
| CXCL9 | chemokine (C-X-C motif) ligand 9 | 0.00720725 |
| ITGBL1 | integrin, beta-like 1 (with EGF-like repeat domains) | 0.00712683 |
| SLC7A8 | solute carrier family 7 (amino acid transporter light chain, L system), member 8 | 0.00707147 |
| CD320 | CD320 molecule | 0.00705705 |
| EMILIN1 | elastin microfibril interfacer 1 | 0.00704148 |
| CADM1 | cell adhesion molecule 1 | 0.00704077 |
| JCAD | junctional cadherin 5 associated | 0.00697041 |
| NUMA1 | nuclear mitotic apparatus protein 1 | 0.00692475 |
| SIM2 | single-minded family bHLH transcription factor 2 | 0.00691329 |
| AMOTL2 | angiomotin like 2 | 0.00689883 |
| PLXNB2 | plexin B2 | 0.00688789 |
| CCP110 | centriolar coiled coil protein 110kDa | 0.00688261 |
| SLC30A1 | solute carrier family 30 (zinc transporter), member 1 | 0.00681669 |
| MCUB | mitochondrial calcium uniporter dominant negative subunit beta | 0.00680636 |
| NACC2 | NACC family member 2, BEN and BTB (POZ) domain containing | 0.0067845 |
| RDH14 | retinol dehydrogenase 14 (all-trans/9-cis/11-cis) | 0.0067779 |
| SLC20A1 | solute carrier family 20 (phosphate transporter), member 1 | 0.00676924 |
| ZBTB20 | zinc finger and BTB domain containing 20 | 0.00676819 |
| CSF2RB | colony stimulating factor 2 receptor, beta, low-affinity (granulocyte-macrophage) | 0.00676723 |
| GNG11 | guanine nucleotide binding protein (G protein), gamma 11 | 0.00675833 |
| MYBL1 | v-myb avian myeloblastosis viral oncogene homolog-like 1 | 0.00675686 |
| MN1 | meningioma (disrupted in balanced translocation) 1 | 0.00675681 |
| PCDH17 | protocadherin 17 | 0.00675643 |
| ADO | 2-aminoethanethiol (cysteamine) dioxygenase | 0.00668604 |
| ZNF512B | zinc finger protein 512B | 0.00665133 |
| CUX1 | cut-like homeobox 1 | 0.00665101 |
| TTC39A | tetratricopeptide repeat domain 39A | 0.00663834 |
| BCHE | butyrylcholinesterase | 0.00662602 |
| ADCY9 | adenylate cyclase 9 | 0.00662106 |
| LGALS1 | lectin, galactoside-binding, soluble, 1 | 0.00661686 |
| SNX1 | sorting nexin 1 | 0.00653322 |
| C7 | complement component 7 | 0.00652624 |
| TALDO1 | transaldolase 1 | 0.00651651 |
| DUSP4 | dual specificity phosphatase 4 | 0.00651465 |
| PPP1R14B | protein phosphatase 1, regulatory (inhibitor) subunit 14B | 0.00650027 |
| MGRN1 | mahogunin ring finger 1, E3 ubiquitin protein ligase | 0.00648033 |
| ANO1 | anoctamin 1, calcium activated chloride channel | 0.0064774 |
| CYP2B6 | cytochrome P450, family 2, subfamily B, polypeptide 6 | 0.00646183 |
| CXCL10 | chemokine (C-X-C motif) ligand 10 | 0.00643457 |
| POLR2L | polymerase (RNA) II (DNA directed) polypeptide L, 7.6kDa | 0.0064332 |
| STIP1 | stress-induced phosphoprotein 1 | 0.00642837 |
| LUM | lumican | 0.00642373 |
| DNMT1 | DNA (cytosine-5-)-methyltransferase 1 | 0.0064208 |
| MT1E | metallothionein 1E | 0.00640549 |
| PHACTR2 | phosphatase and actin regulator 2 | 0.00639886 |
| MMP2 | matrix metallopeptidase 2 | 0.00639875 |
| FRY | furry homolog (Drosophila) | 0.00639269 |
| CTSZ | cathepsin Z | 0.00638949 |
| CERK | ceramide kinase | 0.0063534 |
| CPE | carboxypeptidase E | 0.00634028 |
| PTCH1 | patched 1 | 0.00633177 |
| TXLNA | taxilin alpha | 0.00631292 |
| JADE2 | jade family PHD finger 2 | 0.00631188 |
| GBP1 | guanylate binding protein 1, interferon-inducible | 0.00630351 |
| RERE | arginine-glutamic acid dipeptide (RE) repeats | 0.00625752 |
| SERPING1 | serpin peptidase inhibitor, clade G (C1 inhibitor), member 1 | 0.00625551 |
| IFIT3 | interferon-induced protein with tetratricopeptide repeats 3 | 0.00624824 |
| KRT18 | keratin 18, type I | 0.00623734 |
| CRISPLD2 | cysteine-rich secretory protein LCCL domain containing 2 | 0.00623524 |
| STUB1 | STIP1 homology and U-box containing protein 1, E3 ubiquitin protein ligase | 0.00622024 |
| RAB3B | RAB3B, member RAS oncogene family | 0.00619631 |
| NCAPD3 | non-SMC condensin II complex, subunit D3 | 0.00619302 |
| TPSAB1 | tryptase alpha/beta 1 | 0.00618344 |
| DACH1 | dachshund family transcription factor 1 | 0.00618266 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | 0.00616366 |
| IFI27 | interferon, alpha-inducible protein 27 | 0.00615004 |
| CEBPB | CCAAT/enhancer binding protein (C/EBP), beta | 0.00613719 |
| THY1 | Thy-1 cell surface antigen | 0.00612796 |
| LY96 | lymphocyte antigen 96 | 0.00611708 |
| JADE1 | jade family PHD finger 1 | 0.0061086 |
| MT1M | metallothionein 1M | 0.00610206 |
| P2RY14 | purinergic receptor P2Y, G-protein coupled, 14 | 0.00610164 |
| SEMA3C | sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3C | 0.00609084 |
| STK25 | serine/threonine kinase 25 | 0.00606969 |
| IER5 | immediate early response 5 | 0.00605724 |
| RASA4 | RAS p21 protein activator 4 | 0.00605486 |
| USP7 | ubiquitin specific peptidase 7 (herpes virus-associated) | 0.00604431 |
| MICAL2 | microtubule associated monooxygenase, calponin and LIM domain containing 2 | 0.00602557 |
| PLXNC1 | plexin C1 | 0.00602293 |
| FEN1 | flap structure-specific endonuclease 1 | 0.00601964 |
| TUFM | Tu translation elongation factor, mitochondrial | 0.00601942 |
| CDH5 | cadherin 5, type 2 (vascular endothelium) | 0.00601012 |
| C4BPA | complement component 4 binding protein, alpha | 0.0060039 |
| RHOD | ras homolog family member D | 0.00600264 |
| SLC39A6 | solute carrier family 39 (zinc transporter), member 6 | 0.0059945 |
| LPCAT1 | lysophosphatidylcholine acyltransferase 1 | 0.00599092 |
| NEFH | neurofilament, heavy polypeptide | 0.00597313 |
| UBR4 | ubiquitin protein ligase E3 component n-recognin 4 | 0.00596565 |
| POLR3E | polymerase (RNA) III (DNA directed) polypeptide E (80kD) | 0.00595563 |
| CCNL2 | cyclin L2 | 0.00594118 |
| ENG | endoglin | 0.00594062 |
| RBM26 | RNA binding motif protein 26 | 0.00590853 |
| HMG20B | high mobility group 20B | 0.00590841 |
| COL15A1 | collagen, type XV, alpha 1 | 0.00590513 |
| PLAU | plasminogen activator, urokinase | 0.00589862 |
| TSPAN4 | tetraspanin 4 | 0.00589556 |
| AP3D1 | adaptor-related protein complex 3, delta 1 subunit | 0.0058891 |
| COL14A1 | collagen, type XIV, alpha 1 | 0.00588821 |
| DEXI | Dexi homolog (mouse) | 0.00588283 |
| TUBA4A | tubulin, alpha 4a | 0.00586895 |
| KMT2A | lysine (K)-specific methyltransferase 2A | 0.00586378 |
| PMEPA1 | prostate transmembrane protein, androgen induced 1 | 0.00584364 |
| ABCB6 | ATP-binding cassette, sub-family B (MDR/TAP), member 6 (Langereis blood group) | 0.00583067 |
| GNA11 | guanine nucleotide binding protein (G protein), alpha 11 (Gq class) | 0.00581672 |
| CIAPIN1 | cytokine induced apoptosis inhibitor 1 | 0.00577266 |
| NELL1 | NEL-like 1 (chicken) | 0.00576416 |
| PFAS | phosphoribosylformylglycinamidine synthase | 0.00576267 |
| COMP | cartilage oligomeric matrix protein | 0.00575189 |
| ABCC3 | ATP-binding cassette, sub-family C (CFTR/MRP), member 3 | 0.00575005 |
| CRTC3 | CREB regulated transcription coactivator 3 | 0.00573909 |
| TYROBP | TYRO protein tyrosine kinase binding protein | 0.00573755 |
| LRIG1 | leucine-rich repeats and immunoglobulin-like domains 1 | 0.00573412 |
| TIMM13 | translocase of inner mitochondrial membrane 13 homolog (yeast) | 0.00571911 |
| ZMIZ1 | zinc finger, MIZ-type containing 1 | 0.00571432 |
| LAMP1 | lysosomal-associated membrane protein 1 | 0.00570617 |
| NAV2 | neuron navigator 2 | 0.00570551 |
| CTDSPL | CTD (carboxy-terminal domain, RNA polymerase II, polypeptide A) small phosphatase-like | 0.00570528 |
| GRK5 | G protein-coupled receptor kinase 5 | 0.00570135 |
| CCND3 | cyclin D3 | 0.00569831 |
| KYNU | kynureninase | 0.00569244 |
| RIN2 | Ras and Rab interactor 2 | 0.00565181 |
| SPEN | spen family transcriptional repressor | 0.00565099 |
| CCL4 | chemokine (C-C motif) ligand 4 | 0.00564728 |
| SFRP4 | secreted frizzled-related protein 4 | 0.00564344 |
| KMT5B | lysine methyltransferase 5B | 0.00563499 |
| LONP1 | lon peptidase 1, mitochondrial | 0.00561991 |
| C1R | complement component 1, r subcomponent | 0.0056144 |
| CDR2L | cerebellar degeneration-related protein 2-like | 0.00561352 |
| KCTD5 | potassium channel tetramerization domain containing 5 | 0.00560729 |
| TRIO | trio Rho guanine nucleotide exchange factor | 0.00560559 |
| TEK | TEK tyrosine kinase, endothelial | 0.00560134 |
| GTF3C1 | general transcription factor IIIC, polypeptide 1, alpha 220kDa | 0.00559921 |
| AXL | AXL receptor tyrosine kinase | 0.00558774 |
| SKIV2L | superkiller viralicidic activity 2-like (S. cerevisiae) | 0.00558772 |
| SEZ6L2 | seizure related 6 homolog (mouse)-like 2 | 0.00557414 |
| PIEZO1 | piezo-type mechanosensitive ion channel component 1 | 0.00555943 |
| ELN | elastin | 0.00552665 |
| F13A1 | coagulation factor XIII, A1 polypeptide | 0.00551436 |
| PLCB3 | phospholipase C, beta 3 (phosphatidylinositol-specific) | 0.00550904 |
| SLTM | SAFB-like, transcription modulator | 0.00550856 |
| AQP1 | aquaporin 1 (Colton blood group) | 0.00550066 |
| AMH | anti-Mullerian hormone | 0.00548739 |
| PDE10A | phosphodiesterase 10A | 0.00547614 |
| FGFR1 | fibroblast growth factor receptor 1 | 0.00547041 |
| TGM2 | transglutaminase 2 | 0.00545829 |
| MAP7D1 | MAP7 domain containing 1 | 0.00545324 |
| ATP8B1 | ATPase, aminophospholipid transporter, class I, type 8B, member 1 | 0.00545291 |
| KCNK3 | potassium channel, two pore domain subfamily K, member 3 | 0.00543854 |
| H1-0 | H1.0 linker histone | 0.00543119 |
| MACROD1 | MACRO domain containing 1 | 0.00543023 |
| PLEK | pleckstrin | 0.0054284 |
| SPP1 | secreted phosphoprotein 1 | 0.00542269 |
| PDPK1 | 3-phosphoinositide dependent protein kinase 1 | 0.00542004 |
| GZMK | granzyme K (granzyme 3; tryptase II) | 0.00542003 |
| CCDC92 | coiled-coil domain containing 92 | 0.0054075 |
| PIP5K1C | phosphatidylinositol-4-phosphate 5-kinase, type I, gamma | 0.00540626 |
| SULT1C2 | sulfotransferase family, cytosolic, 1C, member 2 | 0.00540096 |
| ABAT | 4-aminobutyrate aminotransferase | 0.00539956 |
| TIE1 | tyrosine kinase with immunoglobulin-like and EGF-like domains 1 | 0.00539583 |
| FADD | Fas (TNFRSF6)-associated via death domain | 0.00539397 |
| RHBDF1 | rhomboid 5 homolog 1 (Drosophila) | 0.00539259 |
| TAP1 | transporter 1, ATP-binding cassette, sub-family B (MDR/TAP) | 0.00537155 |
| MS4A4A | membrane-spanning 4-domains, subfamily A, member 4A | 0.00536175 |
| GATA2 | GATA binding protein 2 | 0.0053593 |
| FBP1 | fructose-1,6-bisphosphatase 1 | 0.00535777 |
| ARMT1 | acidic residue methyltransferase 1 | 0.00535311 |
| IGF1 | insulin-like growth factor 1 (somatomedin C) | 0.00534797 |
| GOLM1 | golgi membrane protein 1 | 0.00534291 |
| LMO2 | LIM domain only 2 (rhombotin-like 1) | 0.00533699 |
| TBC1D16 | TBC1 domain family, member 16 | 0.00533658 |
| CACNA2D2 | calcium channel, voltage-dependent, alpha 2/delta subunit 2 | 0.00533308 |
| SEC24C | SEC24 family member C | 0.00532922 |
| CPM | carboxypeptidase M | 0.00532828 |
| CPS1 | carbamoyl-phosphate synthase 1, mitochondrial | 0.00532821 |
| HDAC4 | histone deacetylase 4 | 0.00531574 |
| CD40 | CD40 molecule, TNF receptor superfamily member 5 | 0.00530503 |
| COL4A2 | collagen, type IV, alpha 2 | 0.00530221 |
| IFITM1 | interferon induced transmembrane protein 1 | 0.00529789 |
| GLS | glutaminase | 0.00529644 |
| TRIM28 | tripartite motif containing 28 | 0.00529567 |
| TGFB1 | transforming growth factor, beta 1 | 0.00529286 |
| RASSF2 | Ras association (RalGDS/AF-6) domain family member 2 | 0.0052874 |
| CFD | complement factor D (adipsin) | 0.00528288 |
| ZBTB16 | zinc finger and BTB domain containing 16 | 0.00527755 |
| Symbol | Name | Standardized Value |
|---|---|---|
| CHP1 | calcineurin-like EF-hand protein 1 | -0.0254656 |
| LTF | lactotransferrin | -0.0197208 |
| BBOX1 | butyrobetaine (gamma), 2-oxoglutarate dioxygenase (gamma-butyrobetaine hydroxylase) 1 | -0.0162343 |
| FABP7 | fatty acid binding protein 7, brain | -0.0160574 |
| ADD3 | adducin 3 (gamma) | -0.0134273 |
| KRT19 | keratin 19, type I | -0.0132675 |
| FCGBP | Fc fragment of IgG binding protein | -0.0130169 |
| H1-2 | H1.2 linker histone, cluster member | -0.0126662 |
| DLK1 | delta-like 1 homolog (Drosophila) | -0.0119794 |
| GNAS | GNAS complex locus | -0.011442 |
| IKZF1 | IKAROS family zinc finger 1 (Ikaros) | -0.0108538 |
| POSTN | periostin, osteoblast specific factor | -0.0108498 |
| SERPINA5 | serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 5 | -0.0104864 |
| TUBB2A | tubulin, beta 2A class IIa | -0.0103979 |
| BAMBI | BMP and activin membrane-bound inhibitor | -0.0102484 |
| CXADR | coxsackie virus and adenovirus receptor | -0.0101446 |
| CETN2 | centrin, EF-hand protein, 2 | -0.0100786 |
| SERPINA3 | serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 3 | -0.00995703 |
| NEBL | nebulette | -0.00975408 |
| DOK5 | docking protein 5 | -0.00954033 |
| SLPI | secretory leukocyte peptidase inhibitor | -0.00936269 |
| CEMIP | cell migration inducing protein, hyaluronan binding | -0.00930063 |
| ATF3 | activating transcription factor 3 | -0.00928441 |
| PCK1 | phosphoenolpyruvate carboxykinase 1 (soluble) | -0.00926001 |
| MLF1 | myeloid leukemia factor 1 | -0.00925476 |
| IKBKE | inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase epsilon | -0.0092504 |
| PITX3 | paired-like homeodomain 3 | -0.00924615 |
| AQP3 | aquaporin 3 (Gill blood group) | -0.00916147 |
| CLCA4 | chloride channel accessory 4 | -0.00909734 |
| COL9A3 | collagen, type IX, alpha 3 | -0.00895865 |
| KLF2 | Kruppel-like factor 2 | -0.00894722 |
| KRT15 | keratin 15, type I | -0.00885845 |
| PDP1 | pyruvate dehyrogenase phosphatase catalytic subunit 1 | -0.00884993 |
| ASS1 | argininosuccinate synthase 1 | -0.00884139 |
| LCN2 | lipocalin 2 | -0.00883916 |
| SCGB1A1 | secretoglobin, family 1A, member 1 (uteroglobin) | -0.00883341 |
| KLF9 | Kruppel-like factor 9 | -0.00865972 |
| RCAN1 | regulator of calcineurin 1 | -0.00864864 |
| MAGEA3 | melanoma antigen family A3 | -0.00856174 |
| AMDHD2 | amidohydrolase domain containing 2 | -0.00855085 |
| MUC4 | mucin 4, cell surface associated | -0.00852023 |
| TSPAN1 | tetraspanin 1 | -0.00843975 |
| KIAA0226L | KIAA0226-like | -0.00842206 |
| KLHL24 | kelch-like family member 24 | -0.00818058 |
| ADI1 | acireductone dioxygenase 1 | -0.00805131 |
| EAPP | E2F-associated phosphoprotein | -0.00799966 |
| IQCG | IQ motif containing G | -0.00796743 |
| S100A7 | S100 calcium binding protein A7 | -0.00795721 |
| GABRP | gamma-aminobutyric acid (GABA) A receptor, pi | -0.00794175 |
| MAP7 | microtubule-associated protein 7 | -0.00791512 |
| TCL1A | T-cell leukemia/lymphoma 1A | -0.00790637 |
| PEG10 | paternally expressed 10 | -0.00787861 |
| FMO1 | flavin containing monooxygenase 1 | -0.00782079 |
| DKK1 | dickkopf WNT signaling pathway inhibitor 1 | -0.00779432 |
| FOXG1 | forkhead box G1 | -0.00779332 |
| DHDDS | dehydrodolichyl diphosphate synthase | -0.00772636 |
| ZNF331 | zinc finger protein 331 | -0.00771712 |
| RETREG1 | reticulophagy regulator 1 | -0.00767323 |
| ANGPT1 | angiopoietin 1 | -0.00765074 |
| PRUNE2 | prune homolog 2 (Drosophila) | -0.00764281 |
| GPC3 | glypican 3 | -0.00764274 |
| FOXC1 | forkhead box C1 | -0.00762408 |
| XIC | X chromosome inactivation center | -0.00761853 |
| CXCL8 | chemokine (C-X-C motif) ligand 8 | -0.00761785 |
| CLCA1 | chloride channel accessory 1 | -0.00760451 |
| CAST | calpastatin | -0.00757722 |
| RARRES1 | retinoic acid receptor responder (tazarotene induced) 1 | -0.0075415 |
| KDELR3 | KDEL (Lys-Asp-Glu-Leu) endoplasmic reticulum protein retention receptor 3 | -0.0074833 |
| PEG3 | paternally expressed 3 | -0.00743808 |
| SYNE3 | spectrin repeat containing, nuclear envelope family member 3 | -0.00743774 |
| WFDC2 | WAP four-disulfide core domain 2 | -0.00741129 |
| CLDN8 | claudin 8 | -0.00740871 |
| RCBTB2 | regulator of chromosome condensation (RCC1) and BTB (POZ) domain containing protein 2 | -0.00738361 |
| POLR2D | polymerase (RNA) II (DNA directed) polypeptide D | -0.00733866 |
| RELB | v-rel avian reticuloendotheliosis viral oncogene homolog B | -0.00733674 |
| MUC2 | mucin 2, oligomeric mucus/gel-forming | -0.00731085 |
| F3 | coagulation factor III (thromboplastin, tissue factor) | -0.00726713 |
| FOLR1 | folate receptor 1 (adult) | -0.00726501 |
| PERP | PERP, TP53 apoptosis effector | -0.00722373 |
| PTP4A1 | protein tyrosine phosphatase type IVA, member 1 | -0.00721413 |
| SLC2A5 | solute carrier family 2 (facilitated glucose/fructose transporter), member 5 | -0.00719557 |
| GNA13 | guanine nucleotide binding protein (G protein), alpha 13 | -0.0071875 |
| EPCAM | epithelial cell adhesion molecule | -0.00717687 |
| RABGAP1L | RAB GTPase activating protein 1-like | -0.00715002 |
| EMX2 | empty spiracles homeobox 2 | -0.00713174 |
| EHF | ets homologous factor | -0.0071272 |
| SEPP1 | selenoprotein P, plasma, 1 | -0.00708041 |
| SELENBP1 | selenium binding protein 1 | -0.00703759 |
| CASP10 | caspase 10, apoptosis-related cysteine peptidase | -0.00703317 |
| GDI2 | GDP dissociation inhibitor 2 | -0.00702203 |
| LPAR6 | lysophosphatidic acid receptor 6 | -0.00699301 |
| GSTA1 | glutathione S-transferase alpha 1 | -0.00693002 |
| PCOLCE2 | procollagen C-endopeptidase enhancer 2 | -0.00692902 |
| GCH1 | GTP cyclohydrolase 1 | -0.00691658 |
| CDH1 | cadherin 1, type 1, E-cadherin (epithelial) | -0.0068119 |
| HDAC9 | histone deacetylase 9 | -0.0067783 |
| PELI2 | pellino E3 ubiquitin protein ligase family member 2 | -0.00674734 |
| MSMB | microseminoprotein, beta- | -0.00674006 |
| MICA | MHC class I polypeptide-related sequence A | -0.00672295 |
| CCNB1IP1 | cyclin B1 interacting protein 1, E3 ubiquitin protein ligase | -0.00669999 |
| TACSTD2 | tumor-associated calcium signal transducer 2 | -0.00669371 |
| SSR3 | signal sequence receptor, gamma (translocon-associated protein gamma) | -0.00665137 |
| TRIM29 | tripartite motif containing 29 | -0.00664359 |
| TSPAN6 | tetraspanin 6 | -0.00663535 |
| HSD11B2 | hydroxysteroid (11-beta) dehydrogenase 2 | -0.00662326 |
| TMOD1 | tropomodulin 1 | -0.0066134 |
| TMEM14A | transmembrane protein 14A | -0.00656612 |
| ARPP19 | cAMP-regulated phosphoprotein, 19kDa | -0.0065168 |
| SMPDL3A | sphingomyelin phosphodiesterase, acid-like 3A | -0.00648665 |
| CLCA2 | chloride channel accessory 2 | -0.0064329 |
| F2RL1 | coagulation factor II (thrombin) receptor-like 1 | -0.00640382 |
| CP | ceruloplasmin (ferroxidase) | -0.00637691 |
| CLDN7 | claudin 7 | -0.00636857 |
| S100A14 | S100 calcium binding protein A14 | -0.0063517 |
| SAT1 | spermidine/spermine N1-acetyltransferase 1 | -0.00632851 |
| PADI2 | peptidyl arginine deiminase, type II | -0.00627663 |
| PTBP3 | polypyrimidine tract binding protein 3 | -0.00627568 |
| S100A10 | S100 calcium binding protein A10 | -0.00626402 |
| ARHGAP15 | Rho GTPase activating protein 15 | -0.00622389 |
| SMAD5 | SMAD family member 5 | -0.00620864 |
| GPRC5A | G protein-coupled receptor, class C, group 5, member A | -0.00620536 |
| HSPA6 | heat shock 70kDa protein 6 (HSP70B') | -0.00617166 |
| KLF4 | Kruppel-like factor 4 (gut) | -0.0061679 |
| BPI | bactericidal/permeability-increasing protein | -0.00616635 |
| APOBEC3B | apolipoprotein B mRNA editing enzyme, catalytic polypeptide-like 3B | -0.00615887 |
| VLDLR | very low density lipoprotein receptor | -0.00614334 |
| ADORA2B | adenosine A2b receptor | -0.00613017 |
| KHDRBS3 | KH domain containing, RNA binding, signal transduction associated 3 | -0.00610964 |
| ZMYM5 | zinc finger, MYM-type 5 | -0.00609988 |
| EN1 | engrailed homeobox 1 | -0.00608128 |
| CXCL1 | chemokine (C-X-C motif) ligand 1 (melanoma growth stimulating activity, alpha) | -0.00606419 |
| KLF6 | Kruppel-like factor 6 | -0.00603527 |
| CSRP2 | cysteine and glycine-rich protein 2 | -0.00602944 |
| RAB4A | RAB4A, member RAS oncogene family | -0.00602911 |
| MGAM | maltase-glucoamylase | -0.00601937 |
| CNN3 | calponin 3, acidic | -0.00601395 |
| GAP43 | growth associated protein 43 | -0.00601264 |
| ATP5F1C | ATP synthase F1 subunit gamma | -0.00601146 |
| DCUN1D4 | DCN1, defective in cullin neddylation 1, domain containing 4 | -0.00600868 |
| CD59 | CD59 molecule, complement regulatory protein | -0.00599064 |
| SPTSSA | serine palmitoyltransferase, small subunit A | -0.00596309 |
| ROPN1B | rhophilin associated tail protein 1B | -0.00594572 |
| CRABP1 | cellular retinoic acid binding protein 1 | -0.00593763 |
| ABI1 | abl-interactor 1 | -0.00592988 |
| YBX3 | Y box binding protein 3 | -0.00591634 |
| KRAS | Kirsten rat sarcoma viral oncogene homolog | -0.00591499 |
| MUC5B | mucin 5B, oligomeric mucus/gel-forming | -0.00591453 |
| ISG20 | interferon stimulated exonuclease gene 20kDa | -0.0059145 |
| SINHCAF | SIN3-HDAC complex associated factor | -0.00588171 |
| TMEM231 | transmembrane protein 231 | -0.00588118 |
| PLA2G2A | phospholipase A2, group IIA (platelets, synovial fluid) | -0.00587423 |
| ELL2 | elongation factor, RNA polymerase II, 2 | -0.00586655 |
| S100B | S100 calcium binding protein B | -0.0058618 |
| HP | haptoglobin | -0.0058611 |
| MYL12B | myosin, light chain 12B, regulatory | -0.00585055 |
| C3ORF52 | chromosome 3 open reading frame 52 | -0.00583638 |
| YPEL5 | yippee-like 5 (Drosophila) | -0.00581787 |
| TMEM168 | transmembrane protein 168 | -0.00581414 |
| PLCG2 | phospholipase C, gamma 2 (phosphatidylinositol-specific) | -0.00580939 |
| PRKAA1 | protein kinase, AMP-activated, alpha 1 catalytic subunit | -0.00580664 |
| PTPRZ1 | protein tyrosine phosphatase, receptor-type, Z polypeptide 1 | -0.00577299 |
| TNFSF10 | tumor necrosis factor (ligand) superfamily, member 10 | -0.00575695 |
| ITM2C | integral membrane protein 2C | -0.00574559 |
| CCDC176 | coiled-coil domain containing 176 | -0.00574201 |
| AKAP12 | A kinase (PRKA) anchor protein 12 | -0.00573982 |
| VRK3 | vaccinia related kinase 3 | -0.00572395 |
| DNAJB9 | DnaJ (Hsp40) homolog, subfamily B, member 9 | -0.00571306 |
| PRB4 | proline-rich protein BstNI subfamily 4 | -0.00571104 |
| CLMN | calmin (calponin-like, transmembrane) | -0.00570288 |
| SPON1 | spondin 1, extracellular matrix protein | -0.00569942 |
| OSTF1 | osteoclast stimulating factor 1 | -0.00569707 |
| MAL | mal, T-cell differentiation protein | -0.00568911 |
| EHBP1 | EH domain binding protein 1 | -0.00568723 |
| CHRNA3 | cholinergic receptor, nicotinic, alpha 3 (neuronal) | -0.0056859 |
| FAR2 | fatty acyl CoA reductase 2 | -0.00568398 |
| SCAMP1 | secretory carrier membrane protein 1 | -0.00565975 |
| PDZK1IP1 | PDZK1 interacting protein 1 | -0.00565891 |
| DRG1 | developmentally regulated GTP binding protein 1 | -0.00565069 |
| TMEM50B | transmembrane protein 50B | -0.00564188 |
| BTG3 | BTG family, member 3 | -0.0056393 |
| H1-4 | H1.4 linker histone, cluster member | -0.00563207 |
| GBA3 | glucosidase, beta, acid 3 (gene/pseudogene) | -0.00562934 |
| NSDHL | NAD(P) dependent steroid dehydrogenase-like | -0.00562375 |
| FXYD3 | FXYD domain containing ion transport regulator 3 | -0.00561641 |
| MAGEA12 | melanoma antigen family A12 | -0.00560037 |
| SLC2A3 | solute carrier family 2 (facilitated glucose transporter), member 3 | -0.00559953 |
| ZNF451 | zinc finger protein 451 | -0.00559737 |
| ID3 | inhibitor of DNA binding 3, dominant negative helix-loop-helix protein | -0.00559281 |
| PRB1 | proline-rich protein BstNI subfamily 1 | -0.00557302 |
| NR1D2 | nuclear receptor subfamily 1, group D, member 2 | -0.00553994 |
| EYA2 | EYA transcriptional coactivator and phosphatase 2 | -0.00551471 |
| NAPG | N-ethylmaleimide-sensitive factor attachment protein, gamma | -0.00551219 |
| CAPN3 | calpain 3, (p94) | -0.00548983 |
| B4GALT1 | UDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 1 | -0.00547942 |
| CRYAB | crystallin, alpha B | -0.00546209 |
| QRSL1 | glutaminyl-tRNA synthase (glutamine-hydrolyzing)-like 1 | -0.00543431 |
| SPA17 | sperm autoantigenic protein 17 | -0.00542816 |
| NR4A2 | nuclear receptor subfamily 4, group A, member 2 | -0.00542628 |
| FZD7 | frizzled class receptor 7 | -0.00542296 |
| BAALC | brain and acute leukemia, cytoplasmic | -0.00539048 |
| CD58 | CD58 molecule | -0.00538604 |
| RSRC1 | arginine/serine-rich coiled-coil 1 | -0.00537913 |
| MARCH3 | membrane-associated ring finger (C3HC4) 3, E3 ubiquitin protein ligase | -0.00535518 |
| TJP2 | tight junction protein 2 | -0.00533299 |
| CEACAM1 | carcinoembryonic antigen-related cell adhesion molecule 1 (biliary glycoprotein) | -0.00532562 |
| SATB2 | SATB homeobox 2 | -0.0053255 |
| TLR5 | toll-like receptor 5 | -0.00532128 |
| SPRY2 | sprouty homolog 2 (Drosophila) | -0.00529234 |
| DCAF16 | DDB1 and CUL4 associated factor 16 | -0.00528915 |
| EFNA3 | ephrin-A3 | -0.00528018 |
| SAR1B | secretion associated, Ras related GTPase 1B | -0.0052737 |
| IFT88 | intraflagellar transport 88 | -0.00527312 |
| VDAC3 | voltage-dependent anion channel 3 | -0.00527198 |
| TDRD12 | tudor domain containing 12 | -0.00527123 |
| SPAG6 | sperm associated antigen 6 | -0.00526079 |
| TXNIP | thioredoxin interacting protein | -0.00525895 |
| STC1 | stanniocalcin 1 | -0.00524472 |
| CD79B | CD79b molecule, immunoglobulin-associated beta | -0.00522141 |
| C12ORF49 | chromosome 12 open reading frame 49 | -0.00522007 |
| CCDC28A | coiled-coil domain containing 28A | -0.00520658 |
| TPPP3 | tubulin polymerization-promoting protein family member 3 | -0.00520404 |
| NME5 | NME/NM23 family member 5 | -0.0051964 |
| CLDN3 | claudin 3 | -0.00519115 |
| TFRC | transferrin receptor | -0.00518778 |
| AFF4 | AF4/FMR2 family, member 4 | -0.00518014 |
| MDM4 | MDM4, p53 regulator | -0.0051712 |
| PIGR | polymeric immunoglobulin receptor | -0.00516516 |
| EIF2S3 | eukaryotic translation initiation factor 2, subunit 3 gamma, 52kDa | -0.00516332 |
| E2F2 | E2F transcription factor 2 | -0.00516161 |
| DDX6 | DEAD (Asp-Glu-Ala-Asp) box helicase 6 | -0.00514792 |
| IRF6 | interferon regulatory factor 6 | -0.00514535 |
| TTYH1 | tweety family member 1 | -0.00514464 |
| AFP | alpha-fetoprotein | -0.00514139 |
| CAPNS1 | calpain, small subunit 1 | -0.00513888 |
| MS4A12 | membrane-spanning 4-domains, subfamily A, member 12 | -0.00513536 |
| MPC1 | mitochondrial pyruvate carrier 1 | -0.00513363 |
| DUSP10 | dual specificity phosphatase 10 | -0.0051126 |
| CIAO2B | cytosolic iron-sulfur assembly component 2B | -0.00510063 |
| TAGLN2 | transgelin 2 | -0.00509948 |
| ATP6V1E1 | ATPase, H+ transporting, lysosomal 31kDa, V1 subunit E1 | -0.00509675 |
| OCRL | oculocerebrorenal syndrome of Lowe | -0.00509673 |
| CHST2 | carbohydrate (N-acetylglucosamine-6-O) sulfotransferase 2 | -0.00509201 |
| DCLK1 | doublecortin-like kinase 1 | -0.00508785 |
| CSTA | cystatin A (stefin A) | -0.00508088 |
| IL2RG | interleukin 2 receptor, gamma | -0.00507835 |
| EIF3E | eukaryotic translation initiation factor 3, subunit E | -0.00507523 |
| DYRK3 | dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 3 | -0.00507125 |
| WASL | Wiskott-Aldrich syndrome-like | -0.00507115 |
| SH3TC1 | SH3 domain and tetratricopeptide repeats 1 | -0.0050601 |
