SEC11C Gene Set

Dataset CM4AI KOLF21J CRISPRi Gene Perturbation Atlas
Category transcriptomics
Type gene perturbation
Description SEC11 homolog C (S. cerevisiae)| (NCBI Entrez Gene Database, 90701)
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Genes

333 genes differentially expressed following the SEC11C gene perturbation from the CM4AI KOLF21J CRISPRi Gene Perturbation Atlas.

increased expression

Symbol Name Standardized Value
TGM4 transglutaminase 4 3.15685
IL1R2 interleukin 1 receptor, type II 3.15685
AVP arginine vasopressin 3.15685
CORO6 coronin 6 3.15685
LBX2 ladybird homeobox 2 3.15685
VCX3A variable charge, X-linked 3A 3.15685
EXOC3L1 exocyst complex component 3-like 1 3.15685
NPIPA7 nuclear pore complex interacting protein family, member A7 3.15685
C8ORF74 chromosome 8 open reading frame 74 3.15685
RGPD4 RANBP2-like and GRIP domain containing 4 3.15685
GPHB5 glycoprotein hormone beta 5 3.15685
C9ORF152 chromosome 9 open reading frame 152 3.15685
SPDYC speedy/RINGO cell cycle regulator family member C 3.15685
NCKAP1L NCK-associated protein 1-like 3.15685
ADAMTSL5 ADAMTS-like 5 3.15685
SLC9A2 solute carrier family 9, subfamily A (NHE2, cation proton antiporter 2), member 2 3.15685
ANKRD34A ankyrin repeat domain 34A 3.15685
MYOM2 myomesin 2 3.15685
UBE2NL ubiquitin-conjugating enzyme E2N-like (gene/pseudogene) 3.15685
ABCA4 ATP-binding cassette, sub-family A (ABC1), member 4 3.15685
MLANA melan-A 3.15685
MS4A3 membrane-spanning 4-domains, subfamily A, member 3 (hematopoietic cell-specific) 3.15685
HNF1A HNF1 homeobox A 3.15685
ASIC3 acid sensing (proton gated) ion channel 3 3.15685
MYO16 myosin XVI 3.15685
GPR179 G protein-coupled receptor 179 3.15685
PSMD9 proteasome (prosome, macropain) 26S subunit, non-ATPase, 9 3.15685
IL17D interleukin 17D 3.15685
PNPLA1 patatin-like phospholipase domain containing 1 3.15685
SPINK6 serine peptidase inhibitor, Kazal type 6 3.15685
KRTAP13-4 keratin associated protein 13-4 3.15685
LRRC73 leucine rich repeat containing 73 3.15685
OR10AG1 olfactory receptor, family 10, subfamily AG, member 1 3.15685
CD180 CD180 molecule 3.15685
FGF4 fibroblast growth factor 4 3.15685
FGFBP2 fibroblast growth factor binding protein 2 3.15685
GAD1 glutamate decarboxylase 1 (brain, 67kDa) 3.15685
PBOV1 prostate and breast cancer overexpressed 1 3.15685
DIRAS3 DIRAS family, GTP-binding RAS-like 3 3.15685
OR51A7 olfactory receptor, family 51, subfamily A, member 7 3.15685
IL22RA1 interleukin 22 receptor, alpha 1 3.15685
CCR6 chemokine (C-C motif) receptor 6 3.15685
SPATA31A6 SPATA31 subfamily A, member 6 3.15685
BSND barttin CLCNK-type chloride channel accessory beta subunit 3.15685
SERPINA10 serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 10 3.15685
ADGRE3 adhesion G protein-coupled receptor E3 3.15685
SLC5A7 solute carrier family 5 (sodium/choline cotransporter), member 7 3.15685
UCN urocortin 3.15685
NR1H4 nuclear receptor subfamily 1, group H, member 4 3.15685
CD274 CD274 molecule 3.15685
PTGDR2 prostaglandin D2 receptor 2 3.15685
CRYAB crystallin, alpha B 3.15685
COX4I2 cytochrome c oxidase subunit IV isoform 2 (lung) 3.15685
C4ORF17 chromosome 4 open reading frame 17 3.15685
PRB4 proline-rich protein BstNI subfamily 4 3.15685
NTRK1 neurotrophic tyrosine kinase, receptor, type 1 3.15685
BBS1 Bardet-Biedl syndrome 1 3.15685
TXNDC8 thioredoxin domain containing 8 (spermatozoa) 3.15685
TLR1 toll-like receptor 1 3.15685
RSPO3 R-spondin 3 3.15685
FNDC7 fibronectin type III domain containing 7 3.15685
OLIG3 oligodendrocyte transcription factor 3 3.15685
IL3 interleukin 3 3.15685
FAM90A1 family with sequence similarity 90, member A1 3.15685
PAX9 paired box 9 3.15685
MBD3L3 methyl-CpG binding domain protein 3-like 3 3.15685
KCNJ9 potassium channel, inwardly rectifying subfamily J, member 9 3.15685
TMEM191B transmembrane protein 191B 3.15685
DNASE2B deoxyribonuclease II beta 3.15685
C8ORF48 chromosome 8 open reading frame 48 3.15685
OLAH oleoyl-ACP hydrolase 3.15685
TNNI1 troponin I type 1 (skeletal, slow) 3.15685
GC group-specific component (vitamin D binding protein) 3.15685
HPR haptoglobin-related protein 3.15685
BTC betacellulin 3.15685
WEE2 WEE1 homolog 2 (S. pombe) 3.15685
ART1 ADP-ribosyltransferase 1 3.15685
CDH17 cadherin 17, LI cadherin (liver-intestine) 3.15685
SIGLEC15 sialic acid binding Ig-like lectin 15 3.15685
TOMT transmembrane O-methyltransferase 3.15685
PDCD1LG2 programmed cell death 1 ligand 2 3.15685
NECTIN4 nectin cell adhesion molecule 4 3.15685
SCNN1B sodium channel, non voltage gated 1 beta subunit 3.15685
LRRC15 leucine rich repeat containing 15 3.15685
SVOP SV2 related protein homolog (rat) 3.15685
KY kyphoscoliosis peptidase 3.15685
KLK15 kallikrein-related peptidase 15 3.15685
ZCCHC12 zinc finger, CCHC domain containing 12 3.15685
KCNN4 potassium channel, calcium activated intermediate/small conductance subfamily N alpha, member 4 3.15685
ALOXE3 arachidonate lipoxygenase 3 3.15685
LMOD2 leiomodin 2 (cardiac) 3.15685
ENTPD8 ectonucleoside triphosphate diphosphohydrolase 8 3.15685
RSPH10B radial spoke head 10 homolog B (Chlamydomonas) 3.15685
TREH trehalase (brush-border membrane glycoprotein) 3.15685
INSM1 insulinoma-associated 1 3.15685
GPR61 G protein-coupled receptor 61 3.15685
COXFA4L2 cytochrome c oxidase hypoxia associated subunit FA4L2 3.15685
MDFIC2 MyoD family inhibitor domain containing 2 3.15685
ZNF831 zinc finger protein 831 3.15685
SMIM43 small integral membrane protein 43 3.15685
PPP1R27 protein phosphatase 1, regulatory subunit 27 3.15685
H3C14 H3 clustered histone 14 3.15685
IL27 interleukin 27 3.15685
OSR1 odd-skipped related transciption factor 1 3.15685
IGIP IgA-inducing protein 3.15685
AKAIN1 A-kinase anchor inhibitor 1 3.15685
NMBR neuromedin B receptor 3.15685
EFCAB12 EF-hand calcium binding domain 12 3.15685
LGALS12 lectin, galactoside-binding, soluble, 12 3.15685
TRIM75 tripartite motif containing 75 3.15685
MOS v-mos Moloney murine sarcoma viral oncogene homolog 3.15685
H2AC1 H2A clustered histone 1 3.15685
DEPP1 DEPP autophagy regulator 1 3.15685
AKNAD1 AKNA domain containing 1 3.15685
LAIR1 leukocyte-associated immunoglobulin-like receptor 1 3.15685
YIPF7 Yip1 domain family, member 7 3.15685
EPX eosinophil peroxidase 3.15685
PRRX1 paired related homeobox 1 3.15685
FNDC1 fibronectin type III domain containing 1 3.15685
TMEM40 transmembrane protein 40 3.15685
PMP2 peripheral myelin protein 2 3.15685
ASB8 ankyrin repeat and SOCS box containing 8 3.15685
CMTM5 CKLF-like MARVEL transmembrane domain containing 5 3.15685
TTR transthyretin 3.15685
MYL10 myosin, light chain 10, regulatory 3.15685
DYNLRB2 dynein, light chain, roadblock-type 2 3.15685
ZMYND15 zinc finger, MYND-type containing 15 3.15685
WDFY4 WDFY family member 4 3.15685
ABCG8 ATP-binding cassette, sub-family G (WHITE), member 8 3.15685
CSTA cystatin A (stefin A) 3.15685
ANKRD2 ankyrin repeat domain 2 (stretch responsive muscle) 3.15685
KCNJ12 potassium channel, inwardly rectifying subfamily J, member 12 3.15685
GPBAR1 G protein-coupled bile acid receptor 1 3.15685
CALHM1 calcium homeostasis modulator 1 3.15685
GPR35 G protein-coupled receptor 35 3.15685
SPI1 Spi-1 proto-oncogene 3.15685
RSPH10B2 radial spoke head 10 homolog B2 (Chlamydomonas) 3.15685
PXT1 peroxisomal, testis specific 1 3.15685
FFAR1 free fatty acid receptor 1 3.15685
EFCAB3 EF-hand calcium binding domain 3 3.15685
TNFSF8 tumor necrosis factor (ligand) superfamily, member 8 3.15685
EPO erythropoietin 3.15685
SERPINB3 serpin peptidase inhibitor, clade B (ovalbumin), member 3 3.15685
RBPJL recombination signal binding protein for immunoglobulin kappa J region-like 3.08918
INSL6 insulin-like 6 3.08918
RP1L1 retinitis pigmentosa 1-like 1 3.08918
RHOJ ras homolog family member J 3.08918
NIPSNAP3B nipsnap homolog 3B (C. elegans) 3.08918
PGBD4 piggyBac transposable element derived 4 3.08918
PIM2 Pim-2 proto-oncogene, serine/threonine kinase 3.07054
CCT2 chaperonin containing TCP1, subunit 2 (beta) 3.07054
CCNI cyclin I 3.07054
LECT2 leukocyte cell-derived chemotaxin 2 2.97626
DYSF dysferlin 2.94218
IPO4 importin 4 2.80884
MGST1 microsomal glutathione S-transferase 1 2.74185
CBX4 chromobox homolog 4 2.72166
SLC3A2 solute carrier family 3 (amino acid transporter heavy chain), member 2 2.70152
TXNDC11 thioredoxin domain containing 11 2.6582
PPP1R16B protein phosphatase 1, regulatory subunit 16B 2.64793
MACIR macrophage immunometabolism regulator 2.64065
FHOD1 formin homology 2 domain containing 1 2.61201
CLCN6 chloride channel, voltage-sensitive 6 2.59364
HMCN2 hemicentin 2 2.56057
DIABLO diablo, IAP-binding mitochondrial protein 2.53879
RGL4 ral guanine nucleotide dissociation stimulator-like 4 2.51421
PSTK phosphoseryl-tRNA kinase 2.49563
COPS2 COP9 signalosome subunit 2 2.49037
PARD3B par-3 family cell polarity regulator beta 2.47204
H3-3B H3.3 histone B 2.45893
EEF1A1 eukaryotic translation elongation factor 1 alpha 1 2.45121
IFT27 intraflagellar transport 27 2.43922
LSM5 LSM5 homolog, U6 small nuclear RNA associated (S. cerevisiae) 2.42357
DMRT1 doublesex and mab-3 related transcription factor 1 2.41791
DAPL1 death associated protein-like 1 2.41791
MAMDC4 MAM domain containing 4 2.41791
ACSL3 acyl-CoA synthetase long-chain family member 3 2.41665
HSD3B7 hydroxy-delta-5-steroid dehydrogenase, 3 beta- and steroid delta-isomerase 7 2.4101
PCDHGB2 protocadherin gamma subfamily B, 2 2.4101
MRC1 mannose receptor, C type 1 2.4101
CLEC6A C-type lectin domain family 6, member A 2.4101
PPP1CC protein phosphatase 1, catalytic subunit, gamma isozyme 2.36627
HPS1 Hermansky-Pudlak syndrome 1 2.35645
PABPN1 poly(A) binding protein, nuclear 1 2.30941
ADM adrenomedullin 2.29518
MBNL1 muscleblind-like splicing regulator 1 2.29518
SRSF9 serine/arginine-rich splicing factor 9 2.28792
UBE2B ubiquitin-conjugating enzyme E2B 2.2768
JSRP1 junctional sarcoplasmic reticulum protein 1 2.26006
B3GALT2 UDP-Gal:betaGlcNAc beta 1,3-galactosyltransferase, polypeptide 2 2.26006
ANGPTL4 angiopoietin-like 4 2.26006
STMN1 stathmin 1 2.26006
CCDC78 coiled-coil domain containing 78 2.26006
UGT1A8 UDP glucuronosyltransferase 1 family, polypeptide A8 2.26006
SNRPD2 small nuclear ribonucleoprotein D2 polypeptide 16.5kDa 2.25621
ERV3-1-ZNF117 ERV3-1-ZNF117 readthrough 2.23042
GFOD1 glucose-fructose oxidoreductase domain containing 1 2.22693
HDAC2 histone deacetylase 2 2.22276
TMED10 transmembrane emp24-like trafficking protein 10 (yeast) 2.21701
GET3 guided entry of tail-anchored proteins factor 3, ATPase 2.21656
AKT3 v-akt murine thymoma viral oncogene homolog 3 2.20719
TASOR2 transcription activation suppressor family member 2 2.18075
TAGLN2 transgelin 2 2.17342
RAD23A RAD23 homolog A (S. cerevisiae) 2.15744
NDUFA13 NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 13 2.15617
ERH enhancer of rudimentary homolog (Drosophila) 2.1429
FABP3 fatty acid binding protein 3, muscle and heart 2.13545
HYOU1 hypoxia up-regulated 1 2.09392
INSIG2 insulin induced gene 2 2.09275
ZHX1 zinc fingers and homeoboxes 1 2.09215
ARSG arylsulfatase G 2.0877
DDHD1 DDHD domain containing 1 2.07744
DDX19A DEAD (Asp-Glu-Ala-Asp) box polypeptide 19A 2.07667
ABI1 abl-interactor 1 2.07667
NAP1L2 nucleosome assembly protein 1-like 2 2.07621
IQCB1 IQ motif containing B1 2.07299
PCDHB2 protocadherin beta 2 2.06981
RRP9 ribosomal RNA processing 9, small subunit (SSU) processome component, homolog (yeast) 2.06144
BTG1 B-cell translocation gene 1, anti-proliferative 2.05531
ACADM acyl-CoA dehydrogenase, C-4 to C-12 straight chain 2.05322
ANXA3 annexin A3 2.05227
CBR1 carbonyl reductase 1 2.04874
GDE1 glycerophosphodiester phosphodiesterase 1 2.03775
PKD2L2 polycystic kidney disease 2-like 2 2.03416
TMEM204 transmembrane protein 204 2.02181
CPEB1 cytoplasmic polyadenylation element binding protein 1 2.01237
ALDH1L2 aldehyde dehydrogenase 1 family, member L2 2.01222
LCA5L Leber congenital amaurosis 5-like 2.00218

decreased expression

Symbol Name Standardized Value
NLRC3 NLR family, CARD domain containing 3 -3.15685
SUSD2 sushi domain containing 2 -3.15685
KRABD3 KRAB domain containing 3 -3.15685
PRPF4B pre-mRNA processing factor 4B -3.15685
KMO kynurenine 3-monooxygenase (kynurenine 3-hydroxylase) -3.15685
ITLN2 intelectin 2 -3.15685
TRPM7 transient receptor potential cation channel, subfamily M, member 7 -3.15685
KANSL2 KAT8 regulatory NSL complex subunit 2 -3.15685
GABRB1 gamma-aminobutyric acid (GABA) A receptor, beta 1 -3.15685
KIF22 kinesin family member 22 -3.13513
ALDH1A1 aldehyde dehydrogenase 1 family, member A1 -3.12853
DENND2D DENN/MADD domain containing 2D -3.12853
GPR55 G protein-coupled receptor 55 -3.07054
FIMP1 fertilization-influencing membrane protein 1 -3.07054
PRSS36 protease, serine, 36 -3.07054
ICAM4 intercellular adhesion molecule 4 (Landsteiner-Wiener blood group) -3.07054
ODAD1 outer dynein arm docking complex subunit 1 -3.07054
IKZF3 IKAROS family zinc finger 3 (Aiolos) -3.07054
CIZ1 CDKN1A interacting zinc finger protein 1 -3.07054
ACP4 acid phosphatase 4 -3.07054
SGCG sarcoglycan, gamma (35kDa dystrophin-associated glycoprotein) -3.07054
GRM6 glutamate receptor, metabotropic 6 -3.07054
PSD4 pleckstrin and Sec7 domain containing 4 -3.07054
KCNE4 potassium channel, voltage gated subfamily E regulatory beta subunit 4 -3.07054
C1ORF87 chromosome 1 open reading frame 87 -3.07054
ALOX15 arachidonate 15-lipoxygenase -3.07054
LRRTM2 leucine rich repeat transmembrane neuronal 2 -3.07054
C1ORF116 chromosome 1 open reading frame 116 -3.07054
SLC4A9 solute carrier family 4, sodium bicarbonate cotransporter, member 9 -3.07054
UPB1 ureidopropionase, beta -3.07054
OPRL1 opiate receptor-like 1 -3.07054
TNFSF13 tumor necrosis factor (ligand) superfamily, member 13 -3.07054
FGF23 fibroblast growth factor 23 -3.07054
ABCC9 ATP-binding cassette, sub-family C (CFTR/MRP), member 9 -3.07054
SLC9C2 solute carrier family 9, member C2 (putative) -3.07054
FAM221B family with sequence similarity 221, member B -3.07054
TMPRSS11A transmembrane protease, serine 11A -3.07054
ZC3H11C zinc finger CCCH-type containing 11C -3.07054
ZNF396 zinc finger protein 396 -3.07054
NTN5 netrin 5 -3.07054
CYS1 cystin 1 -3.07054
SLC24A4 solute carrier family 24 (sodium/potassium/calcium exchanger), member 4 -3.07054
ALDH3B1 aldehyde dehydrogenase 3 family, member B1 -3.07054
MAMLD1 mastermind-like domain containing 1 -3.07054
SMIM22 small integral membrane protein 22 -3.07054
XKR3 XK, Kell blood group complex subunit-related family, member 3 -3.07054
NOX3 NADPH oxidase 3 -3.07054
NOX1 NADPH oxidase 1 -3.07054
OR56B1 olfactory receptor, family 56, subfamily B, member 1 -3.07054
AZU1 azurocidin 1 -3.07054
GPRC5A G protein-coupled receptor, class C, group 5, member A -3.07054
COL17A1 collagen, type XVII, alpha 1 -3.07054
PPP1R3G protein phosphatase 1, regulatory subunit 3G -3.07054
DNAH8 dynein, axonemal, heavy chain 8 -3.07054
BRD2 bromodomain containing 2 -3.06303
SMOC1 SPARC related modular calcium binding 1 -3.03548
IER3IP1 immediate early response 3 interacting protein 1 -2.87687
ACOT6 acyl-CoA thioesterase 6 -2.83561
GRIN3B glutamate receptor, ionotropic, N-methyl-D-aspartate 3B -2.83404
DCHS2 dachsous cadherin-related 2 -2.63314
DNAAF4 dynein axonemal assembly factor 4 -2.59167
CBX5 chromobox homolog 5 -2.56
RHBDL2 rhomboid, veinlet-like 2 (Drosophila) -2.49563
DCDC1 doublecortin domain containing 1 -2.49563
KLHL42 kelch-like family member 42 -2.49259
FLACC1 flagellum associated containing coiled-coil domains 1 -2.49037
GBA1 glucosylceramidase beta 1 -2.49037
CCDC178 coiled-coil domain containing 178 -2.49037
CYP4Z1 cytochrome P450, family 4, subfamily Z, polypeptide 1 -2.49037
ITPRID1 ITPR interacting domain containing 1 -2.49037
CREM cAMP responsive element modulator -2.48895
MATN1 matrilin 1, cartilage matrix protein -2.48346
ECSCR endothelial cell surface expressed chemotaxis and apoptosis regulator -2.41791
GSTM2 glutathione S-transferase mu 2 (muscle) -2.4101
ZNF480 zinc finger protein 480 -2.39869
TRIT1 tRNA isopentenyltransferase 1 -2.3941
SVBP small vasohibin binding protein -2.33965
FARP2 FERM, RhoGEF and pleckstrin domain protein 2 -2.33936
RPAP1 RNA polymerase II associated protein 1 -2.32025
KANK1 KN motif and ankyrin repeat domains 1 -2.32025
IL17C interleukin 17C -2.29518
NOL3 nucleolar protein 3 (apoptosis repressor with CARD domain) -2.23042
TMEM62 transmembrane protein 62 -2.23042
MADCAM1 mucosal vascular addressin cell adhesion molecule 1 -2.22809
FBP1 fructose-1,6-bisphosphatase 1 -2.22809
MYH2 myosin, heavy chain 2, skeletal muscle, adult -2.22276
HIST1H2BF histone cluster 1, H2bf -2.22276
EVC Ellis van Creveld protein -2.22276
ZNF518A zinc finger protein 518A -2.21792
CYCS cytochrome c, somatic -2.20719
GDI1 GDP dissociation inhibitor 1 -2.18048
HPD 4-hydroxyphenylpyruvate dioxygenase -2.15019
SYCE3 synaptonemal complex central element protein 3 -2.15019
SNAI2 snail family zinc finger 2 -2.15019
PHF20L1 PHD finger protein 20-like 1 -2.14606
MPI mannose phosphate isomerase -2.14206
SLC9A9 solute carrier family 9, subfamily A (NHE9, cation proton antiporter 9), member 9 -2.1354
MTSS2 MTSS I-BAR domain containing 2 -2.1138
CYP39A1 cytochrome P450, family 39, subfamily A, polypeptide 1 -2.10176
BCKDHA branched chain keto acid dehydrogenase E1, alpha polypeptide -2.08587
HTATIP2 HIV-1 Tat interactive protein 2, 30kDa -2.07669
IER2 immediate early response 2 -2.04167
NUCB1 nucleobindin 1 -2.03683
ANKRD13D ankyrin repeat domain 13 family, member D -2.0156
DDX3X DEAD (Asp-Glu-Ala-Asp) box helicase 3, X-linked -2.01237