SEC22C Gene Set

Dataset CM4AI KOLF21J CRISPRi Gene Perturbation Atlas
Category transcriptomics
Type gene perturbation
Description SEC22 vesicle trafficking protein homolog C (S. cerevisiae)|This gene encodes a member of the SEC22 family of vesicle trafficking proteins. The encoded protein is localized to the endoplasmic reticulum and may play a role in the early stages of ER-Golgi protein trafficking. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. [provided by RefSeq, Jan 2011] (NCBI Entrez Gene Database, 9117)
Similar Terms
Downloads & Tools

Genes

351 genes differentially expressed following the SEC22C gene perturbation from the CM4AI KOLF21J CRISPRi Gene Perturbation Atlas.

increased expression

Symbol Name Standardized Value
DAO D-amino-acid oxidase 3.14506
CYP2E1 cytochrome P450, family 2, subfamily E, polypeptide 1 3.14506
NCMAP noncompact myelin associated protein 3.14506
PGAM4 phosphoglycerate mutase family member 4 3.14506
MILR1 mast cell immunoglobulin-like receptor 1 3.14506
CNTNAP4 contactin associated protein-like 4 3.14506
KRT28 keratin 28, type I 3.14506
RIMBP2 RIMS binding protein 2 3.14506
TNFSF15 tumor necrosis factor (ligand) superfamily, member 15 3.14506
NRAP nebulin-related anchoring protein 3.14506
SPINK4 serine peptidase inhibitor, Kazal type 4 3.14506
GNLY granulysin 3.14506
RP1L1 retinitis pigmentosa 1-like 1 3.14506
FAM43B family with sequence similarity 43, member B 3.14506
CLDN9 claudin 9 3.14506
PCDHB12 protocadherin beta 12 3.14506
RS1 retinoschisin 1 3.14506
SCARA5 scavenger receptor class A, member 5 3.14506
COL19A1 collagen, type XIX, alpha 1 3.14506
ENPP3 ectonucleotide pyrophosphatase/phosphodiesterase 3 3.14506
CFAP74 cilia and flagella associated protein 74 3.14506
CARD18 caspase recruitment domain family, member 18 3.14506
LRRC14B leucine rich repeat containing 14B 3.14506
NME5 NME/NM23 family member 5 3.14506
AADACL3 arylacetamide deacetylase-like 3 3.14506
COPZ2 coatomer protein complex, subunit zeta 2 3.14506
LRRC63 leucine rich repeat containing 63 3.14506
RHO rhodopsin 3.14506
LOC105378220 macrophage receptor MARCO-like 3.14506
ABCA4 ATP-binding cassette, sub-family A (ABC1), member 4 3.14506
TMEM132C transmembrane protein 132C 3.14506
ZNF804A zinc finger protein 804A 3.14506
TECTB tectorin beta 3.14506
MIXL1 Mix paired-like homeobox 3.14506
PSCA prostate stem cell antigen 3.14506
MS4A14 membrane-spanning 4-domains, subfamily A, member 14 3.14506
C1ORF146 chromosome 1 open reading frame 146 3.14506
MUC5B mucin 5B, oligomeric mucus/gel-forming 3.14506
GDNF glial cell derived neurotrophic factor 3.14506
TUBB8 tubulin, beta 8 class VIII 3.14506
KCNRG potassium channel regulator 3.14506
SLC26A1 solute carrier family 26 (anion exchanger), member 1 3.14506
ANKRD34A ankyrin repeat domain 34A 3.14506
PTGFR prostaglandin F receptor (FP) 3.14506
ADAMTSL5 ADAMTS-like 5 3.14506
ABCG5 ATP-binding cassette, sub-family G (WHITE), member 5 3.14506
ERAP2 endoplasmic reticulum aminopeptidase 2 3.14506
ZC3H11C zinc finger CCCH-type containing 11C 3.14506
GPR33 G protein-coupled receptor 33 (gene/pseudogene) 3.14506
RHCG Rh family, C glycoprotein 3.14506
ELOVL3 ELOVL fatty acid elongase 3 3.14506
APOBEC3A apolipoprotein B mRNA editing enzyme, catalytic polypeptide-like 3A 3.14506
MIOX myo-inositol oxygenase 3.14506
RTL1 retrotransposon-like 1 3.14506
OR51M1 olfactory receptor, family 51, subfamily M, member 1 3.14506
KCND3 potassium channel, voltage gated Shal related subfamily D, member 3 3.14506
HTR3B 5-hydroxytryptamine (serotonin) receptor 3B, ionotropic 3.14506
CLDN14 claudin 14 3.14506
ANGPTL8 angiopoietin like 8 3.14506
CCNQ cyclin Q 3.14506
CIMIP7 ciliary microtubule inner protein 7 3.14506
LOC124903233 uncharacterized LOC124903233 3.14506
H3C13 H3 clustered histone 13 3.14506
RAMACL RNA guanine-7 methyltransferase activating subunit like 3.14506
SMIM35 small integral membrane protein 35 3.14506
CCDC197 coiled-coil domain containing 197 3.14506
CHCT1 CHD1 helical C-terminal domain containing 1 3.14506
KASH5 KASH domain containing 5 3.14506
LORICRIN loricrin cornified envelope precursor protein 3.14506
POU2F3 POU class 2 homeobox 3 3.14506
DLK1 delta-like 1 homolog (Drosophila) 3.14506
SOAT2 sterol O-acyltransferase 2 3.14506
MIA melanoma inhibitory activity 3.14506
SLC45A2 solute carrier family 45, member 2 3.14506
LOC124901449 uncharacterized LOC124901449 3.14506
GDF10 growth differentiation factor 10 3.14506
AWAT1 acyl-CoA wax alcohol acyltransferase 1 3.14506
ADGRG1 adhesion G protein-coupled receptor G1 3.14506
SP140 SP140 nuclear body protein 3.14506
LIX1 Lix1 homolog (chicken) 3.14506
SCN10A sodium channel, voltage gated, type X alpha subunit 3.14506
APOBEC4 apolipoprotein B mRNA editing enzyme, catalytic polypeptide-like 4 (putative) 3.14506
ARHGEF38 Rho guanine nucleotide exchange factor (GEF) 38 3.14506
TBX5 T-box 5 3.14506
PCDHGC3 protocadherin gamma subfamily C, 3 3.14506
ROPN1 rhophilin associated tail protein 1 3.14506
PINLYP phospholipase A2 inhibitor and LY6/PLAUR domain containing 3.14506
LRRC72 leucine rich repeat containing 72 3.14506
STARD6 StAR-related lipid transfer (START) domain containing 6 3.14506
VCX3A variable charge, X-linked 3A 3.14506
PGA5 pepsinogen 5, group I (pepsinogen A) 3.14506
S100G S100 calcium binding protein G 3.14506
CDSN corneodesmosin 3.14506
CLIP4 CAP-GLY domain containing linker protein family, member 4 3.14506
CCL19 chemokine (C-C motif) ligand 19 3.14506
SIGLEC11 sialic acid binding Ig-like lectin 11 3.14506
TFAP2D transcription factor AP-2 delta (activating enhancer binding protein 2 delta) 3.14506
KRT1 keratin 1, type II 3.14506
SLCO2B1 solute carrier organic anion transporter family, member 2B1 3.14506
ACOX2 acyl-CoA oxidase 2, branched chain 3.14506
PRR35 proline rich 35 3.14506
GFI1B growth factor independent 1B transcription repressor 3.14506
CHIT1 chitinase 1 (chitotriosidase) 3.14506
ATP10B ATPase, class V, type 10B 3.14506
MBOAT4 membrane bound O-acyltransferase domain containing 4 3.14506
FZD1 frizzled class receptor 1 3.14506
RUFY4 RUN and FYVE domain containing 4 3.14506
SLFN12L schlafen family member 12-like 3.14506
PKDREJ polycystin (PKD) family receptor for egg jelly 3.14506
MAGEB17 melanoma antigen family B17 3.14506
PAG1 phosphoprotein membrane anchor with glycosphingolipid microdomains 1 3.14506
TBPL2 TATA box binding protein like 2 3.14506
PGR progesterone receptor 3.14506
GNA15 guanine nucleotide binding protein (G protein), alpha 15 (Gq class) 3.14506
UTS2B urotensin 2B 3.14506
SLC6A13 solute carrier family 6 (neurotransmitter transporter), member 13 3.14506
TREH trehalase (brush-border membrane glycoprotein) 3.14506
MAB21L2 mab-21-like 2 (C. elegans) 3.14506
ODF1 outer dense fiber of sperm tails 1 3.14506
C22ORF42 chromosome 22 open reading frame 42 3.14506
SERPINA5 serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 5 3.14506
CHI3L2 chitinase 3-like 2 3.14506
COMP cartilage oligomeric matrix protein 3.14506
XKR3 XK, Kell blood group complex subunit-related family, member 3 3.14506
KAZALD1 Kazal-type serine peptidase inhibitor domain 1 3.14506
KLK12 kallikrein-related peptidase 12 3.14506
DYDC1 DPY30 domain containing 1 3.14506
KLK11 kallikrein-related peptidase 11 3.14506
EFCAB3 EF-hand calcium binding domain 3 3.14506
PIH1D1 PIH1 domain containing 1 3.14506
HHATL hedgehog acyltransferase-like 3.14506
CXCR4 chemokine (C-X-C motif) receptor 4 3.14506
DCLK3 doublecortin-like kinase 3 3.14506
TMIGD2 transmembrane and immunoglobulin domain containing 2 3.14506
FGF7 fibroblast growth factor 7 3.14506
TTC36 tetratricopeptide repeat domain 36 3.14506
GOLGA8T golgin A8 family, member T 3.14506
LYZL4 lysozyme-like 4 3.14506
ADAM18 ADAM metallopeptidase domain 18 3.14506
GPRC6A G protein-coupled receptor, class C, group 6, member A 3.14506
TSKS testis-specific serine kinase substrate 3.14506
MS4A12 membrane-spanning 4-domains, subfamily A, member 12 3.14506
GCM1 glial cells missing homolog 1 (Drosophila) 3.14506
TGM1 transglutaminase 1 3.14506
ADAM20 ADAM metallopeptidase domain 20 3.14506
PCDHGA12 protocadherin gamma subfamily A, 12 3.14506
ZCCHC12 zinc finger, CCHC domain containing 12 3.14506
TMEM52B transmembrane protein 52B 3.14506
HOXD13 homeobox D13 3.14506
OR52N2 olfactory receptor, family 52, subfamily N, member 2 3.14506
LRRC24 leucine rich repeat containing 24 3.14506
CCDC170 coiled-coil domain containing 170 3.14506
PTCRA pre T-cell antigen receptor alpha 3.14506
RNF224 ring finger protein 224 3.14506
SLC38A3 solute carrier family 38, member 3 3.14506
CARD6 caspase recruitment domain family, member 6 3.14506
TSPAN32 tetraspanin 32 3.14506
MOS v-mos Moloney murine sarcoma viral oncogene homolog 3.14506
NUTM2D NUT family member 2D 3.14506
PSG8 pregnancy specific beta-1-glycoprotein 8 3.14506
GSC2 goosecoid homeobox 2 3.14506
ANKRD33 ankyrin repeat domain 33 3.14506
DDX4 DEAD (Asp-Glu-Ala-Asp) box polypeptide 4 3.14506
CYP2D6 cytochrome P450, family 2, subfamily D, polypeptide 6 3.14506
RBM4 RNA binding motif protein 4 3.08129
CALML4 calmodulin-like 4 3.01509
CAPG capping protein (actin filament), gelsolin-like 2.95628
EMSY EMSY transcriptional repressor, BRCA2 interacting 2.95628
CCDC181 coiled-coil domain containing 181 2.88466
B3GAT1 beta-1,3-glucuronyltransferase 1 2.87455
YBX3 Y box binding protein 3 2.78768
CALM2 calmodulin 2 (phosphorylase kinase, delta) 2.78215
RHOBTB3 Rho-related BTB domain containing 3 2.71583
EBNA1BP2 EBNA1 binding protein 2 2.67775
OSBPL7 oxysterol binding protein-like 7 2.67775
H3C6 H3 clustered histone 6 2.67775
LGALS3BP lectin, galactoside-binding, soluble, 3 binding protein 2.56279
ANAPC16 anaphase promoting complex subunit 16 2.54849
LRRC58 leucine rich repeat containing 58 2.54458
KLHL14 kelch-like family member 14 2.49785
POU5F2 POU domain class 5, transcription factor 2 2.49785
POP7 processing of precursor 7, ribonuclease P/MRP subunit (S. cerevisiae) 2.4928
YLPM1 YLP motif containing 1 2.46933
APELA apelin receptor early endogenous ligand 2.45549
ETV7 ets variant 7 2.41661
COG3 component of oligomeric golgi complex 3 2.41661
MINK1 misshapen-like kinase 1 2.4016
H2BC26 H2B clustered histone 26 2.39431
TMPRSS6 transmembrane protease, serine 6 2.39431
DUSP23 dual specificity phosphatase 23 2.39396
FURIN furin (paired basic amino acid cleaving enzyme) 2.39396
SORBS1 sorbin and SH3 domain containing 1 2.3931
BLCAP bladder cancer associated protein 2.38681
C1GALT1 core 1 synthase, glycoprotein-N-acetylgalactosamine 3-beta-galactosyltransferase 1 2.38637
ARHGAP28 Rho GTPase activating protein 28 2.36384
KCND2 potassium channel, voltage gated Shal related subfamily D, member 2 2.35004
TK1 thymidine kinase 1, soluble 2.34576
ZNF316 zinc finger protein 316 2.34486
RBM18 RNA binding motif protein 18 2.33703
NRXN1 neurexin 1 2.30934
KIAA1586 KIAA1586 2.29519
EFNA3 ephrin-A3 2.29001
PDE12 phosphodiesterase 12 2.26714
SNRPG small nuclear ribonucleoprotein polypeptide G 2.26513
DNAJC1 DnaJ (Hsp40) homolog, subfamily C, member 1 2.24087
RHOA ras homolog family member A 2.23854
MIA3 melanoma inhibitory activity family, member 3 2.23854
LMO2 LIM domain only 2 (rhombotin-like 1) 2.21861
CCNA1 cyclin A1 2.21861
FLT4 fms-related tyrosine kinase 4 2.21861
VSTM2L V-set and transmembrane domain containing 2 like 2.21861
FNDC11 fibronectin type III domain containing 11 2.21861
SAP30L SAP30-like 2.21861
NUDT7 nudix (nucleoside diphosphate linked moiety X)-type motif 7 2.21861
NDUFA2 NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 2, 8kDa 2.21796
TBCB tubulin folding cofactor B 2.19601
YKT6 YKT6 v-SNARE homolog (S. cerevisiae) 2.14986
C6ORF47 chromosome 6 open reading frame 47 2.14663
HPF1 histone PARylation factor 1 2.14541
IL15RA interleukin 15 receptor, alpha 2.12784
NUCB1 nucleobindin 1 2.12696
EIF2B3 eukaryotic translation initiation factor 2B, subunit 3 gamma, 58kDa 2.10143
NUP153 nucleoporin 153kDa 2.0888
GCN1 GCN1 activator of EIF2AK4 2.08795
ANGEL1 angel homolog 1 (Drosophila) 2.08678
FUBP1 far upstream element (FUSE) binding protein 1 2.08282
ACTN3 actinin, alpha 3 (gene/pseudogene) 2.08002
ATG2B autophagy related 2B 2.07184
PKNOX1 PBX/knotted 1 homeobox 1 2.06005
SNAP47 synaptosomal-associated protein, 47kDa 2.05086
AP5M1 adaptor-related protein complex 5, mu 1 subunit 2.04952
PGBD1 piggyBac transposable element derived 1 2.04658
FBXO10 F-box protein 10 2.031
FAAH2 fatty acid amide hydrolase 2 2.01952

decreased expression

Symbol Name Standardized Value
KLF5 Kruppel-like factor 5 (intestinal) -3.14506
NIPAL2 NIPA-like domain containing 2 -3.14506
RAB40A RAB40A, member RAS oncogene family -3.14506
ADAMTS5 ADAM metallopeptidase with thrombospondin type 1 motif, 5 -3.14506
LPAR4 lysophosphatidic acid receptor 4 -3.14506
SPAG4 sperm associated antigen 4 -3.14506
NEFM neurofilament, medium polypeptide -3.14506
SS18L2 synovial sarcoma translocation gene on chromosome 18-like 2 -3.14506
GSDME gasdermin E -3.14506
SULT1C2 sulfotransferase family, cytosolic, 1C, member 2 -3.14506
CPTP ceramide-1-phosphate transfer protein -3.14506
PNPLA7 patatin-like phospholipase domain containing 7 -3.14506
PIM1 Pim-1 proto-oncogene, serine/threonine kinase -3.05104
C11ORF86 chromosome 11 open reading frame 86 -2.95628
HSD3B7 hydroxy-delta-5-steroid dehydrogenase, 3 beta- and steroid delta-isomerase 7 -2.95628
CA1 carbonic anhydrase I -2.95628
GNAT2 guanine nucleotide binding protein (G protein), alpha transducing activity polypeptide 2 -2.95628
RPL3L ribosomal protein L3-like -2.95628
ZNF324B zinc finger protein 324B -2.95628
CHL1 cell adhesion molecule L1-like -2.95628
ICAM2 intercellular adhesion molecule 2 -2.95628
GPR179 G protein-coupled receptor 179 -2.95628
SYCP3 synaptonemal complex protein 3 -2.95628
VSTM2B V-set and transmembrane domain containing 2B -2.95628
IL6ST-DT IL6ST divergent transcript -2.95628
IHO1 interactor of HORMAD1 1 -2.95628
CFAP299 cilia and flagella associated protein 299 -2.95628
LMNTD2 lamin tail domain containing 2 -2.95628
BDKRB2 bradykinin receptor B2 -2.95628
ZNF441 zinc finger protein 441 -2.95628
KLRF1 killer cell lectin-like receptor subfamily F, member 1 -2.95628
SUMO4 small ubiquitin-like modifier 4 -2.95628
FAM178B family with sequence similarity 178, member B -2.95628
ZBTB16 zinc finger and BTB domain containing 16 -2.95628
TFPI tissue factor pathway inhibitor (lipoprotein-associated coagulation inhibitor) -2.95628
GJA5 gap junction protein, alpha 5, 40kDa -2.95628
GJA4 gap junction protein, alpha 4, 37kDa -2.95628
SPMAP2L sperm microtubule associated protein 2 like -2.95628
NXPH4 neurexophilin 4 -2.95628
ADRA1D adrenoceptor alpha 1D -2.95628
SLC34A2 solute carrier family 34 (type II sodium/phosphate cotransporter), member 2 -2.95628
CLIC2 chloride intracellular channel 2 -2.95628
PCDHB15 protocadherin beta 15 -2.95628
BCL2L10 BCL2-like 10 (apoptosis facilitator) -2.95628
IP6K3 inositol hexakisphosphate kinase 3 -2.95628
TEX19 testis expressed 19 -2.95628
NGFR nerve growth factor receptor -2.95628
LYPD5 LY6/PLAUR domain containing 5 -2.95628
SIAH3 siah E3 ubiquitin protein ligase family member 3 -2.95628
PCDHGA8 protocadherin gamma subfamily A, 8 -2.95628
TSPAN16 tetraspanin 16 -2.95628
THEM6 thioesterase superfamily member 6 -2.95628
SYT5 synaptotagmin V -2.95628
ATP2A1 ATPase, Ca++ transporting, cardiac muscle, fast twitch 1 -2.89961
AKAP5 A kinase (PRKA) anchor protein 5 -2.87455
H2AC20 H2A clustered histone 20 -2.81716
ADRA2C adrenoceptor alpha 2C -2.77473
INPP5J inositol polyphosphate-5-phosphatase J -2.77473
C4ORF33 chromosome 4 open reading frame 33 -2.77473
ETS1 v-ets avian erythroblastosis virus E26 oncogene homolog 1 -2.73882
PRKCI protein kinase C, iota -2.66519
SDF2 stromal cell-derived factor 2 -2.65018
PPT1 palmitoyl-protein thioesterase 1 -2.60154
TFAM transcription factor A, mitochondrial -2.55766
PSMC6 proteasome (prosome, macropain) 26S subunit, ATPase, 6 -2.54849
DHX15 DEAH (Asp-Glu-Ala-His) box helicase 15 -2.54849
DDX47 DEAD (Asp-Glu-Ala-Asp) box polypeptide 47 -2.49726
SERF1B small EDRK-rich factor 1B (centromeric) -2.49726
CASP10 caspase 10, apoptosis-related cysteine peptidase -2.49726
TRIM38 tripartite motif containing 38 -2.40053
RHOB ras homolog family member B -2.39217
OPA3 optic atrophy 3 (autosomal recessive, with chorea and spastic paraplegia) -2.38698
CEBPD CCAAT/enhancer binding protein (C/EBP), delta -2.38681
SLC2A14 solute carrier family 2 (facilitated glucose transporter), member 14 -2.37904
UNC93B1 unc-93 homolog B1 (C. elegans) -2.35004
HPD 4-hydroxyphenylpyruvate dioxygenase -2.35004
SLC5A2 solute carrier family 5 (sodium/glucose cotransporter), member 2 -2.35004
OXCT2 3-oxoacid CoA transferase 2 -2.35004
CAMK2A calcium/calmodulin-dependent protein kinase II alpha -2.35004
ANKRD54 ankyrin repeat domain 54 -2.34892
BROX BRO1 domain and CAAX motif containing -2.33931
CENPA centromere protein A -2.30093
ZNF548 zinc finger protein 548 -2.29202
CLDND1 claudin domain containing 1 -2.25896
SH3D19 SH3 domain containing 19 -2.25456
NEK1 NIMA-related kinase 1 -2.24785
IVD isovaleryl-CoA dehydrogenase -2.23983
ZNF254 zinc finger protein 254 -2.21861
ZNF75A zinc finger protein 75a -2.21861
TNFRSF1A tumor necrosis factor receptor superfamily, member 1A -2.21861
LRRC37B leucine rich repeat containing 37B -2.2108
ABCA3 ATP-binding cassette, sub-family A (ABC1), member 3 -2.20848
CDHR2 cadherin-related family member 2 -2.20848
CACNA1G calcium channel, voltage-dependent, T type, alpha 1G subunit -2.20848
KBTBD12 kelch repeat and BTB (POZ) domain containing 12 -2.20848
ABCB10 ATP-binding cassette, sub-family B (MDR/TAP), member 10 -2.17255
RAPGEF1 Rap guanine nucleotide exchange factor (GEF) 1 -2.16674
RCBTB1 regulator of chromosome condensation (RCC1) and BTB (POZ) domain containing protein 1 -2.16067
SEC22C SEC22 vesicle trafficking protein homolog C (S. cerevisiae) -2.143
TNXB tenascin XB -2.143
FER1L5 fer-1-like family member 5 -2.13788
ADA2 adenosine deaminase 2 -2.13657
OPCML opioid binding protein/cell adhesion molecule-like -2.11045
ICAM1 intercellular adhesion molecule 1 -2.11015
TRPC6 transient receptor potential cation channel, subfamily C, member 6 -2.11015
CCDC74B coiled-coil domain containing 74B -2.11015
GABBR2 gamma-aminobutyric acid (GABA) B receptor, 2 -2.11015
MROH8 maestro heat-like repeat family member 8 -2.11015
MTG1 mitochondrial ribosome-associated GTPase 1 -2.09491
PTPRJ protein tyrosine phosphatase, receptor type, J -2.09207
GLG1 golgi glycoprotein 1 -2.08282
MED20 mediator complex subunit 20 -2.08282
GCLC glutamate-cysteine ligase, catalytic subunit -2.0828
BTBD9 BTB (POZ) domain containing 9 -2.04952
ARHGEF17 Rho guanine nucleotide exchange factor (GEF) 17 -2.04464
SUMF1 sulfatase modifying factor 1 -2.03384
TAF3 TAF3 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 140kDa -2.01291