SEC24C Gene Set

Dataset CM4AI KOLF21J CRISPRi Gene Perturbation Atlas
Category transcriptomics
Type gene perturbation
Description SEC24 family member C|The protein encoded by this gene is a member of the SEC24 subfamily of the SEC23/SEC24 family, which is involved in vesicle trafficking. The encoded protein has similarity to yeast Sec24p component of COPII. COPII is the coat protein complex responsible for vesicle budding from the ER. The product of this gene may play a role in shaping the vesicle, as well as in cargo selection and concentration. Alternatively spliced transcript variants encoding the same protein have been identified. [provided by RefSeq, Jul 2008] (NCBI Entrez Gene Database, 9632)
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Genes

344 genes differentially expressed following the SEC24C gene perturbation from the CM4AI KOLF21J CRISPRi Gene Perturbation Atlas.

increased expression

Symbol Name Standardized Value
COL19A1 collagen, type XIX, alpha 1 4.15747
RRAD Ras-related associated with diabetes 4.15747
IL5RA interleukin 5 receptor, alpha 4.15747
NME5 NME/NM23 family member 5 4.15747
LMO1 LIM domain only 1 (rhombotin 1) 4.15747
PAX7 paired box 7 4.15747
C6ORF58 chromosome 6 open reading frame 58 4.15747
DMRTC1B DMRT-like family C1B 4.15747
CEP295NL CEP295 N-terminal like 4.15747
NEU4 sialidase 4 4.15747
MUC1 mucin 1, cell surface associated 4.15747
MUC6 mucin 6, oligomeric mucus/gel-forming 4.15747
TMPRSS11D transmembrane protease, serine 11D 4.15747
PLEKHG7 pleckstrin homology domain containing, family G (with RhoGef domain) member 7 4.15747
ENPP6 ectonucleotide pyrophosphatase/phosphodiesterase 6 4.15747
LY86 lymphocyte antigen 86 4.15747
RXFP2 relaxin/insulin-like family peptide receptor 2 4.15747
LIPN lipase, family member N 4.15747
SCN2B sodium channel, voltage gated, type II beta subunit 4.15747
HEATR9 HEAT repeat containing 9 4.15747
PRELP proline/arginine-rich end leucine-rich repeat protein 4.15747
KCNRG potassium channel regulator 4.15747
OTUD6A OTU deubiquitinase 6A 4.15747
GADL1 glutamate decarboxylase-like 1 4.15747
CORO6 coronin 6 4.15747
GALR2 galanin receptor 2 4.15747
CPLX4 complexin 4 4.15747
HMX1 H6 family homeobox 1 4.15747
ABCA4 ATP-binding cassette, sub-family A (ABC1), member 4 4.15747
PNLDC1 poly(A)-specific ribonuclease (PARN)-like domain containing 1 4.15747
FGF6 fibroblast growth factor 6 4.15747
SCIN scinderin 4.15747
ZC2HC1B zinc finger, C2HC-type containing 1B 4.15747
CYP26A1 cytochrome P450, family 26, subfamily A, polypeptide 1 4.15747
LBX2 ladybird homeobox 2 4.15747
RPL3L ribosomal protein L3-like 4.15747
LCN12 lipocalin 12 4.15747
KCNE1 potassium channel, voltage gated subfamily E regulatory beta subunit 1 4.15747
CRX cone-rod homeobox 4.15747
C8ORF74 chromosome 8 open reading frame 74 4.15747
LRRIQ4 leucine-rich repeats and IQ motif containing 4 4.15747
DLK1 delta-like 1 homolog (Drosophila) 4.15747
NAA11 N(alpha)-acetyltransferase 11, NatA catalytic subunit 4.15747
CRYGC crystallin, gamma C 4.15747
R3HDML R3H domain containing-like 4.15747
ACR acrosin 4.15747
CSNK2A2IP casein kinase 2 subunit alpha' interacting protein 4.15747
OPRM1 opioid receptor, mu 1 4.15747
SPI1 Spi-1 proto-oncogene 4.15747
HTRA4 HtrA serine peptidase 4 4.15747
STX11 syntaxin 11 4.15747
VSIG8 V-set and immunoglobulin domain containing 8 4.15747
HTR3C 5-hydroxytryptamine (serotonin) receptor 3C, ionotropic 4.15747
HTR3E 5-hydroxytryptamine (serotonin) receptor 3E, ionotropic 4.15747
ABCA9 ATP-binding cassette, sub-family A (ABC1), member 9 4.15747
GATA2 GATA binding protein 2 4.15747
GBP6 guanylate binding protein family, member 6 4.15747
HAO2 hydroxyacid oxidase 2 (long chain) 4.15747
SPMIP9 sperm microtubule inner protein 9 4.15747
CPNE8-AS1 CPNE8 antisense RNA 1 4.15747
CTXND1 cortexin domain containing 1 4.15747
FYB2 FYN binding protein 2 4.15747
ITPRID1 ITPR interacting domain containing 1 4.15747
RTL5 retrotransposon Gag like 5 4.15747
AJM1 apical junction component 1 homolog 4.15747
GPRASP3 G protein-coupled receptor associated sorting protein family member 3 4.15747
ODAD1 outer dynein arm docking complex subunit 1 4.15747
UGT2A1 UDP glucuronosyltransferase 2 family, polypeptide A1, complex locus 4.15747
GDF6 growth differentiation factor 6 4.15747
TAS1R1 taste receptor, type 1, member 1 4.15747
TNFRSF19 tumor necrosis factor receptor superfamily, member 19 4.15747
ITK IL2-inducible T-cell kinase 4.15747
DEFB1 defensin, beta 1 4.15747
TUBA3D tubulin, alpha 3d 4.15747
ARL5C ADP-ribosylation factor-like 5C 4.15747
RHOXF2 Rhox homeobox family, member 2 4.15747
PCDHA7 protocadherin alpha 7 4.15747
ATP13A4 ATPase type 13A4 4.15747
ERAS ES cell expressed Ras 4.15747
CD79A CD79a molecule, immunoglobulin-associated alpha 4.15747
CATSPER3 cation channel, sperm associated 3 4.15747
PGA5 pepsinogen 5, group I (pepsinogen A) 4.15747
CELA2A chymotrypsin-like elastase family, member 2A 4.15747
EXOC3L1 exocyst complex component 3-like 1 4.15747
PLEKHD1 pleckstrin homology domain containing, family D (with coiled-coil domains) member 1 4.15747
MYH13 myosin, heavy chain 13, skeletal muscle 4.15747
CXCL16 chemokine (C-X-C motif) ligand 16 4.15747
CXCL14 chemokine (C-X-C motif) ligand 14 4.15747
TMEM236 transmembrane protein 236 4.15747
SLC22A25 solute carrier family 22, member 25 4.15747
MEP1A meprin A, alpha (PABA peptide hydrolase) 4.15747
DCAF12L2 DDB1 and CUL4 associated factor 12-like 2 4.15747
ANKRD63 ankyrin repeat domain 63 4.15747
NOX1 NADPH oxidase 1 4.15747
RTBDN retbindin 4.15747
PLET1 placenta expressed transcript 1 4.15747
TRADD TNFRSF1A-associated via death domain 4.15747
PKDREJ polycystin (PKD) family receptor for egg jelly 4.15747
SERINC4 serine incorporator 4 4.15747
C11ORF16 chromosome 11 open reading frame 16 4.15747
SLC6A12 solute carrier family 6 (neurotransmitter transporter), member 12 4.15747
CXCR5 chemokine (C-X-C motif) receptor 5 4.15747
GRK7 G protein-coupled receptor kinase 7 4.15747
ALAS2 5'-aminolevulinate synthase 2 4.15747
AKNAD1 AKNA domain containing 1 4.15747
SLC25A52 solute carrier family 25, member 52 4.15747
APOD apolipoprotein D 4.15747
CCL25 chemokine (C-C motif) ligand 25 4.15747
ERICH6 glutamate-rich 6 4.15747
NOG noggin 4.15747
CEBPE CCAAT/enhancer binding protein (C/EBP), epsilon 4.15747
MAMDC4 MAM domain containing 4 4.15747
APOC3 apolipoprotein C-III 4.15747
MRAP melanocortin 2 receptor accessory protein 4.15747
RSPH10B radial spoke head 10 homolog B (Chlamydomonas) 4.15747
TYR tyrosinase 4.15747
GPR146 G protein-coupled receptor 146 4.15747
SERPINB3 serpin peptidase inhibitor, clade B (ovalbumin), member 3 4.15747
CXORF58 chromosome X open reading frame 58 4.15747
EOMES eomesodermin 4.15747
BTG4 B-cell translocation gene 4 4.15747
SLC36A2 solute carrier family 36 (proton/amino acid symporter), member 2 4.15747
VMO1 vitelline membrane outer layer 1 homolog (chicken) 4.15747
UPK1A uroplakin 1A 4.15747
DCT dopachrome tautomerase 4.15747
PENK proenkephalin 4.15747
ZCCHC12 zinc finger, CCHC domain containing 12 4.15747
IL17REL interleukin 17 receptor E-like 4.15747
FBXO40 F-box protein 40 4.15747
TRHR thyrotropin-releasing hormone receptor 4.15747
UTS2B urotensin 2B 4.15747
CRYBA1 crystallin, beta A1 4.15747
B4GALNT2 beta-1,4-N-acetyl-galactosaminyl transferase 2 4.15747
NR5A1 nuclear receptor subfamily 5, group A, member 1 4.15747
TMEM31 transmembrane protein 31 4.15747
GSDMA gasdermin A 4.15747
SCGB1A1 secretoglobin, family 1A, member 1 (uteroglobin) 4.15747
C9ORF57 chromosome 9 open reading frame 57 4.15747
LRRC74A leucine rich repeat containing 74A 4.15747
ZMYND10 zinc finger, MYND-type containing 10 4.15747
ACKR1 atypical chemokine receptor 1 (Duffy blood group) 4.15747
TBC1D28 TBC1 domain family, member 28 4.15747
PTGDR prostaglandin D2 receptor (DP) 4.15747
ANKRD62 ankyrin repeat domain 62 4.15747
KMO kynurenine 3-monooxygenase (kynurenine 3-hydroxylase) 4.15747
TCN1 transcobalamin I (vitamin B12 binding protein, R binder family) 4.15747
CARD9 caspase recruitment domain family, member 9 4.15747
NUTM2B NUT family member 2B 4.15747
HTR4 5-hydroxytryptamine (serotonin) receptor 4, G protein-coupled 4.15747
SLC44A4 solute carrier family 44, member 4 4.15747
GRAPL GRB2-related adaptor protein-like 4.15747
GALNT15 polypeptide N-acetylgalactosaminyltransferase 15 4.15747
APOL1 apolipoprotein L, 1 4.15747
PFN4 profilin family, member 4 4.15747
CMTM5 CKLF-like MARVEL transmembrane domain containing 5 4.15747
SMYD1 SET and MYND domain containing 1 4.15747
PIK3R6 phosphoinositide-3-kinase, regulatory subunit 6 4.15747
ANGPTL3 angiopoietin-like 3 4.15747
HPCAL4 hippocalcin like 4 4.09238
AFP alpha-fetoprotein 3.99135
SEC22C SEC22 vesicle trafficking protein homolog C (S. cerevisiae) 3.67529
CCR5AS CCR5 antisense RNA 3.4803
TRIM39 tripartite motif containing 39 3.42875
ORC2 origin recognition complex, subunit 2 3.42875
ACSL6 acyl-CoA synthetase long-chain family member 6 3.21051
CRHR1 corticotropin releasing hormone receptor 1 3.21051
ECE2 endothelin converting enzyme 2 3.21051
NPIPA2 nuclear pore complex interacting protein family, member A2 3.21051
KLK14 kallikrein-related peptidase 14 3.21051
ZNF582 zinc finger protein 582 3.21051
RPS12 ribosomal protein S12 3.20265
RPS17 ribosomal protein S17 3.17977
ARHGAP33 Rho GTPase activating protein 33 3.1017
TMEM87B transmembrane protein 87B 3.02442
TOB1 transducer of ERBB2, 1 2.96636
LEPROTL1 leptin receptor overlapping transcript-like 1 2.96232
MRPS33 mitochondrial ribosomal protein S33 2.92553
TFIP11 tuftelin interacting protein 11 2.82449
CLIP2 CAP-GLY domain containing linker protein 2 2.81417
FOXB1 forkhead box B1 2.78811
NPY neuropeptide Y 2.75299
TPO thyroid peroxidase 2.69242
SPIDR scaffolding protein involved in DNA repair 2.61538
CLYBL citrate lyase beta like 2.603
CCDC61 coiled-coil domain containing 61 2.52936
FARS2 phenylalanyl-tRNA synthetase 2, mitochondrial 2.52148
RITA1 RBPJ interacting and tubulin associated 1 2.49991
LMNB2 lamin B2 2.49563
MLIP muscular LMNA-interacting protein 2.47455
ROBO1 roundabout, axon guidance receptor, homolog 1 (Drosophila) 2.46406
NKD2 naked cuticle homolog 2 (Drosophila) 2.46406
APCDD1 adenomatosis polyposis coli down-regulated 1 2.46406
ADCY10 adenylate cyclase 10 (soluble) 2.46406
IL1R1 interleukin 1 receptor, type I 2.46406
LRRC63 leucine rich repeat containing 63 2.42998
PRKAR2B protein kinase, cAMP-dependent, regulatory, type II, beta 2.42998
FPR3 formyl peptide receptor 3 2.42998
LRRC32 leucine rich repeat containing 32 2.42998
RABAC1 Rab acceptor 1 (prenylated) 2.41616
AQP5 aquaporin 5 2.41616
TRPC4 transient receptor potential cation channel, subfamily C, member 4 2.38016
MT1F metallothionein 1F 2.35887
EIF4A1 eukaryotic translation initiation factor 4A1 2.30599
RING1 ring finger protein 1 2.30599
IFT81 intraflagellar transport 81 2.28505
GART phosphoribosylglycinamide formyltransferase, phosphoribosylglycinamide synthetase, phosphoribosylaminoimidazole synthetase 2.23296
PRKAR1A protein kinase, cAMP-dependent, regulatory, type I, alpha 2.21871
MYO10 myosin X 2.21309
REPS1 RALBP1 associated Eps domain containing 1 2.20519
APOLTP apolipoprotein lipid transfer particle homolog 2.20233
TBCC tubulin folding cofactor C 2.20233
APOE apolipoprotein E 2.16789
PSENEN presenilin enhancer gamma secretase subunit 2.14097
TGFBR3L transforming growth factor, beta receptor III-like 2.13423
ZNF232 zinc finger protein 232 2.12775
SERAC1 serine active site containing 1 2.11183
CCNP cyclin P 2.11183
PIGU phosphatidylinositol glycan anchor biosynthesis, class U 2.09751
FLT4 fms-related tyrosine kinase 4 2.08732
LRP2BP LRP2 binding protein 2.08395
ERCC8 excision repair cross-complementation group 8 2.07535
ZNF655 zinc finger protein 655 2.06822
ZNF251 zinc finger protein 251 2.06243
GRM3 glutamate receptor, metabotropic 3 2.06243
GAPVD1 GTPase activating protein and VPS9 domains 1 2.06232
AKR7A2 aldo-keto reductase family 7, member A2 (aflatoxin aldehyde reductase) 2.04391
B4GALT4 UDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 4 2.01549
ZNF284 zinc finger protein 284 2.00609
RPL35 ribosomal protein L35 2.00376
PCLO piccolo presynaptic cytomatrix protein 2.00032

decreased expression

Symbol Name Standardized Value
BAIAP2L2 BAI1-associated protein 2-like 2 -4.15747
CLSTN2 calsyntenin 2 -4.15747
RPH3A rabphilin 3A -4.15747
SYNPO2L synaptopodin 2-like -4.15747
KCNJ11 potassium channel, inwardly rectifying subfamily J, member 11 -4.15747
BRF2 BRF2, RNA polymerase III transcription initiation factor 50 kDa subunit -4.15747
IL4I1 interleukin 4 induced 1 -4.15747
GDPGP1 GDP-D-glucose phosphorylase 1 -4.15747
SYT13 synaptotagmin XIII -4.15747
GFRA3 GDNF family receptor alpha 3 -3.83669
SPTBN5 spectrin, beta, non-erythrocytic 5 -3.83669
TICAM1 toll-like receptor adaptor molecule 1 -3.83669
VIT vitrin -3.83669
TGM1 transglutaminase 1 -3.83669
DNAH1 dynein, axonemal, heavy chain 1 -3.83669
GGN gametogenetin -3.83669
CA7 carbonic anhydrase VII -3.83669
ARHGEF15 Rho guanine nucleotide exchange factor (GEF) 15 -3.83669
BRICD5 BRICHOS domain containing 5 -3.83669
LYNX1 Ly6/neurotoxin 1 -3.83669
AIFM3 apoptosis-inducing factor, mitochondrion-associated, 3 -3.83669
STK31 serine/threonine kinase 31 -3.83669
THEMIS thymocyte selection associated -3.83669
ST8SIA4 ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransferase 4 -3.83669
FRMD1 FERM domain containing 1 -3.83669
SH3RF2 SH3 domain containing ring finger 2 -3.83669
IRF9 interferon regulatory factor 9 -3.83669
SDS serine dehydratase -3.83669
ZPBP zona pellucida binding protein -3.83669
SEL1L2 sel-1 suppressor of lin-12-like 2 (C. elegans) -3.83669
IFIT1B interferon-induced protein with tetratricopeptide repeats 1B -3.83669
ELFN2 extracellular leucine-rich repeat and fibronectin type III domain containing 2 -3.83669
KLB klotho beta -3.83669
VWF von Willebrand factor -3.83669
CNGA4 cyclic nucleotide gated channel alpha 4 -3.83669
SFRP4 secreted frizzled-related protein 4 -3.83669
NPIPB7 nuclear pore complex interacting protein family, member B7 -3.83669
CATSPER4 cation channel, sperm associated 4 -3.83669
TSGA10IP testis specific, 10 interacting protein -3.83669
SCRIB scribbled planar cell polarity protein -3.57096
RGS2 regulator of G-protein signaling 2 -3.5526
BCL2L13 BCL2-like 13 (apoptosis facilitator) -3.20653
HTR3A 5-hydroxytryptamine (serotonin) receptor 3A, ionotropic -3.02158
PBXIP1 pre-B-cell leukemia homeobox interacting protein 1 -3.02158
TICAM2 toll-like receptor adaptor molecule 2 -3.02032
ASTN1 astrotactin 1 -3.01651
SAXO2 stabilizer of axonemal microtubules 2 -3.00894
NFKBIL1 nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor-like 1 -2.96927
FBXO15 F-box protein 15 -2.96232
ERCC5 excision repair cross-complementation group 5 -2.81669
PDE11A phosphodiesterase 11A -2.80059
BET1L Bet1 golgi vesicular membrane trafficking protein-like -2.77856
ITFG2 integrin alpha FG-GAP repeat containing 2 -2.76076
SF3B2 splicing factor 3b, subunit 2, 145kDa -2.7257
SLC35C1 solute carrier family 35 (GDP-fucose transporter), member C1 -2.65579
REEP3 receptor accessory protein 3 -2.64314
CIP2A cellular inhibitor of PP2A -2.62964
SBNO1 strawberry notch homolog 1 (Drosophila) -2.61283
GALC galactosylceramidase -2.603
ZC3H10 zinc finger CCCH-type containing 10 -2.50266
PECR peroxisomal trans-2-enoyl-CoA reductase -2.49569
REEP1 receptor accessory protein 1 -2.46406
SVEP1 sushi, von Willebrand factor type A, EGF and pentraxin domain containing 1 -2.46406
ZBTB41 zinc finger and BTB domain containing 41 -2.44775
LURAP1 leucine rich adaptor protein 1 -2.43138
SEC24C SEC24 family member C -2.42355
GPX7 glutathione peroxidase 7 -2.4133
ZNG1A Zn regulated GTPase metalloprotein activator 1A -2.40889
BLOC1S1 biogenesis of lysosomal organelles complex-1, subunit 1 -2.38496
MAPRE2 microtubule-associated protein, RP/EB family, member 2 -2.38496
COL5A3 collagen, type V, alpha 3 -2.37284
ZBTB12 zinc finger and BTB domain containing 12 -2.34932
RLN1 relaxin 1 -2.34932
MYOZ1 myozenin 1 -2.34932
FKBPL FK506 binding protein like -2.34932
DRAM1 DNA-damage regulated autophagy modulator 1 -2.34932
ZFP28 ZFP28 zinc finger protein -2.34932
LYSMD2 LysM, putative peptidoglycan-binding, domain containing 2 -2.34932
NDNF neuron-derived neurotrophic factor -2.34932
C8ORF34 chromosome 8 open reading frame 34 -2.34932
CORT cortistatin -2.34932
CNBD1 cyclic nucleotide binding domain containing 1 -2.29021
WNK2 WNK lysine deficient protein kinase 2 -2.29021
ZNG1B Zn regulated GTPase metalloprotein activator 1B -2.29021
NICOL1 NELL2 interacting cell ontogeny regulator 1 -2.29021
QRFPR pyroglutamylated RFamide peptide receptor -2.28848
TMBIM4 transmembrane BAX inhibitor motif containing 4 -2.27762
ENAH enabled homolog (Drosophila) -2.26072
FAM228B family with sequence similarity 228, member B -2.25602
OSGEPL1 O-sialoglycoprotein endopeptidase-like 1 -2.22325
ACER2 alkaline ceramidase 2 -2.21309
C2CD4C C2 calcium-dependent domain containing 4C -2.20233
RAB27B RAB27B, member RAS oncogene family -2.20233
MDGA1 MAM domain containing glycosylphosphatidylinositol anchor 1 -2.20233
CDH12 cadherin 12, type 2 (N-cadherin 2) -2.20233
MANEAL mannosidase, endo-alpha-like -2.20233
ANKRD31 ankyrin repeat domain 31 -2.20233
SOWAHD sosondowah ankyrin repeat domain family member D -2.20233
TMEM154 transmembrane protein 154 -2.20062
SERPINI2 serpin peptidase inhibitor, clade I (pancpin), member 2 -2.17513
SCD5 stearoyl-CoA desaturase 5 -2.17513
IL17C interleukin 17C -2.17513
FAH fumarylacetoacetate hydrolase (fumarylacetoacetase) -2.17425
TMEM68 transmembrane protein 68 -2.16789
RANBP10 RAN binding protein 10 -2.14097
PVR poliovirus receptor -2.14057
NR2C1 nuclear receptor subfamily 2, group C, member 1 -2.09851
ANKRD18B ankyrin repeat domain 18B -2.09473
MRPS5 mitochondrial ribosomal protein S5 -2.08521
KIF22 kinesin family member 22 -2.05869
MRS2 MRS2 magnesium transporter -2.04961
EHBP1L1 EH domain binding protein 1-like 1 -2.04589
ITGB3BP integrin beta 3 binding protein (beta3-endonexin) -2.00609
FAM227B family with sequence similarity 227, member B -2.00032