SEC61G Gene Set

Dataset CM4AI KOLF21J CRISPRi Gene Perturbation Atlas
Category transcriptomics
Type gene perturbation
Description Sec61 gamma subunit|The Sec61 complex is the central component of the protein translocation apparatus of the endoplasmic reticulum (ER) membrane. Oligomers of the Sec61 complex form a transmembrane channel where proteins are translocated across and integrated into the ER membrane. This complex consists of three membrane proteins- alpha, beta, and gamma. This gene encodes the gamma-subunit protein. Alternatively spliced transcript variants encoding the same protein have been identified. [provided by RefSeq, Jul 2008] (NCBI Entrez Gene Database, 23480)
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Genes

627 genes differentially expressed following the SEC61G gene perturbation from the CM4AI KOLF21J CRISPRi Gene Perturbation Atlas.

increased expression

Symbol Name Standardized Value
ID3 inhibitor of DNA binding 3, dominant negative helix-loop-helix protein 2.5389
DBP D site of albumin promoter (albumin D-box) binding protein 2.5389
DEF6 differentially expressed in FDCP 6 homolog (mouse) 2.5389
ACP5 acid phosphatase 5, tartrate resistant 2.5389
TOR3A torsin family 3, member A 2.5389
TICRR TOPBP1-interacting checkpoint and replication regulator 2.5389
ADAMTS4 ADAM metallopeptidase with thrombospondin type 1 motif, 4 2.5389
RASL11B RAS-like, family 11, member B 2.5389
MYD88 myeloid differentiation primary response 88 2.5389
ENTPD5 ectonucleoside triphosphate diphosphohydrolase 5 2.5389
MECOM MDS1 and EVI1 complex locus 2.5389
EPOR erythropoietin receptor 2.5389
ETAA1 Ewing tumor-associated antigen 1 2.5389
CTSB cathepsin B 2.5389
COPS7A COP9 signalosome subunit 7A 2.5389
CHRM2 cholinergic receptor, muscarinic 2 2.5389
XKR8 XK, Kell blood group complex subunit-related family, member 8 2.5389
ZNF783 zinc finger family member 783 2.5389
PPM1N protein phosphatase, Mg2+/Mn2+ dependent, 1N (putative) 2.5389
RASEF RAS and EF-hand domain containing 2.5389
P4HA2 prolyl 4-hydroxylase, alpha polypeptide II 2.5389
TBC1D19 TBC1 domain family, member 19 2.5389
TOMM20L translocase of outer mitochondrial membrane 20 homolog (yeast)-like 2.5389
FRMD8 FERM domain containing 8 2.5389
ZNF684 zinc finger protein 684 2.5389
MAPK7 mitogen-activated protein kinase 7 2.5389
TNC tenascin C 2.5389
FBXO43 F-box protein 43 2.5389
MYOZ3 myozenin 3 2.5389
DLL3 delta-like 3 (Drosophila) 2.5389
TDRD7 tudor domain containing 7 2.5389
WDR17 WD repeat domain 17 2.5389
PAQR9 progestin and adipoQ receptor family member IX 2.5389
STAB2 stabilin 2 2.5389
CFAP144 cilia and flagella associated protein 144 2.5389
RHBDL2 rhomboid, veinlet-like 2 (Drosophila) 2.5389
ACOT6 acyl-CoA thioesterase 6 2.5389
ZNF285 zinc finger protein 285 2.5389
MRGPRF MAS-related GPR, member F 2.5389
BCHE butyrylcholinesterase 2.5389
TRMT10A tRNA methyltransferase 10 homolog A (S. cerevisiae) 2.5389
LRRC27 leucine rich repeat containing 27 2.5389
ZNF114 zinc finger protein 114 2.5389
CHPF chondroitin polymerizing factor 2.5389
PFKFB4 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 4 2.5389
PARP12 poly (ADP-ribose) polymerase family, member 12 2.5389
ZNF454 zinc finger protein 454 2.5389
ZNF304 zinc finger protein 304 2.5389
TMC4 transmembrane channel-like 4 2.5389
APOBEC3C apolipoprotein B mRNA editing enzyme, catalytic polypeptide-like 3C 2.51067
PPFIA3 protein tyrosine phosphatase, receptor type, f polypeptide (PTPRF), interacting protein (liprin), alpha 3 2.51067
CPS1 carbamoyl-phosphate synthase 1, mitochondrial 2.47402
HAS3 hyaluronan synthase 3 2.44805
TSPAN12 tetraspanin 12 2.40614
ZNF584 zinc finger protein 584 2.31311
PIP5KL1 phosphatidylinositol-4-phosphate 5-kinase-like 1 2.31311
DCAF4L1 DDB1 and CUL4 associated factor 4-like 1 2.31311
P2RY2 purinergic receptor P2Y, G-protein coupled, 2 2.31311
NXPH3 neurexophilin 3 2.31311
MEP1B meprin A, beta 2.31311
CCPG1 cell cycle progression 1 2.31311
ZNF461 zinc finger protein 461 2.31311
SLC16A13 solute carrier family 16, member 13 2.31311
MOCS1 molybdenum cofactor synthesis 1 2.31311
ADAMTS9 ADAM metallopeptidase with thrombospondin type 1 motif, 9 2.31311
BTN3A2 butyrophilin, subfamily 3, member A2 2.31311
RASL10A RAS-like, family 10, member A 2.31311
SOX8 SRY (sex determining region Y)-box 8 2.31311
MAPRE3 microtubule-associated protein, RP/EB family, member 3 2.31311
ADAMTS5 ADAM metallopeptidase with thrombospondin type 1 motif, 5 2.31311
AKT1S1 AKT1 substrate 1 (proline-rich) 2.31311
SACK1G scaffolding CK1 anchoring protein G 2.31311
NR1H3 nuclear receptor subfamily 1, group H, member 3 2.31311
SOX9 SRY (sex determining region Y)-box 9 2.31311
AIP aryl hydrocarbon receptor interacting protein 2.31311
NPPC natriuretic peptide C 2.31311
XPNPEP2 X-prolyl aminopeptidase (aminopeptidase P) 2, membrane-bound 2.31311
ENPEP glutamyl aminopeptidase (aminopeptidase A) 2.31311
SLC6A2 solute carrier family 6 (neurotransmitter transporter), member 2 2.31311
ZNF469 zinc finger protein 469 2.31311
FSCN3 fascin actin-bundling protein 3, testicular 2.31311
SHISA5 shisa family member 5 2.31311
ELK1 ELK1, member of ETS oncogene family 2.31311
RGPD1 RANBP2-like and GRIP domain containing 1 2.31311
KCNIP2 Kv channel interacting protein 2 2.31311
KHDC3L KH domain containing 3-like, subcortical maternal complex member 2.31311
SERPINF2 serpin peptidase inhibitor, clade F (alpha-2 antiplasmin, pigment epithelium derived factor), member 2 2.31311
SMIM3 small integral membrane protein 3 2.31311
GPD1L glycerol-3-phosphate dehydrogenase 1-like 2.31311
OR6A2 olfactory receptor, family 6, subfamily A, member 2 2.31311
TTLL9 tubulin tyrosine ligase-like family member 9 2.31311
ERLIN1 ER lipid raft associated 1 2.31311
DPPA2 developmental pluripotency associated 2 2.31311
PCGF5 polycomb group ring finger 5 2.31311
PCGF1 polycomb group ring finger 1 2.31311
ZNF696 zinc finger protein 696 2.31311
NAPB N-ethylmaleimide-sensitive factor attachment protein, beta 2.31311
C1ORF146 chromosome 1 open reading frame 146 2.31311
ADAMTSL2 ADAMTS-like 2 2.31311
PNMA2 paraneoplastic Ma antigen 2 2.31311
ZNF311 zinc finger protein 311 2.31311
ZBTB49 zinc finger and BTB domain containing 49 2.31311
SGPP2 sphingosine-1-phosphate phosphatase 2 2.31311
CCDC69 coiled-coil domain containing 69 2.31311
MATK megakaryocyte-associated tyrosine kinase 2.31311
MEF2C myocyte enhancer factor 2C 2.31311
SULT1A2 sulfotransferase family, cytosolic, 1A, phenol-preferring, member 2 2.31311
ZNF157 zinc finger protein 157 2.31311
FNDC7 fibronectin type III domain containing 7 2.31311
SLC30A3 solute carrier family 30 (zinc transporter), member 3 2.31311
C1GALT1C1 C1GALT1-specific chaperone 1 2.31311
CROT carnitine O-octanoyltransferase 2.31311
SLC23A1 solute carrier family 23 (ascorbic acid transporter), member 1 2.31311
CRYL1 crystallin, lambda 1 2.31311
LYNX1 Ly6/neurotoxin 1 2.31311
ARHGEF12 Rho guanine nucleotide exchange factor (GEF) 12 2.31311
MRO maestro 2.31311
ABHD14B abhydrolase domain containing 14B 2.31311
DPP7 dipeptidyl-peptidase 7 2.31311
MNMIP1 manchette microtubule inner protein 1 2.31311
ELOVL1 ELOVL fatty acid elongase 1 2.31311
GOLGA6L10 golgin A6 family-like 10 2.31311
FKBP2 FK506 binding protein 2, 13kDa 2.31311
GRAMD1C GRAM domain containing 1C 2.31311
EFNB1 ephrin-B1 2.31311
ZNF77 zinc finger protein 77 2.31311
FIMP1 fertilization-influencing membrane protein 1 2.31311
CEACAM1 carcinoembryonic antigen-related cell adhesion molecule 1 (biliary glycoprotein) 2.31311
LPIN3 lipin 3 2.31311
VWA5A von Willebrand factor A domain containing 5A 2.31311
SPATA21 spermatogenesis associated 21 2.31311
CMKLR1 chemerin chemokine-like receptor 1 2.31311
ACTL6B actin-like 6B 2.31311
EMILIN2 elastin microfibril interfacer 2 2.31311
ZSCAN30 zinc finger and SCAN domain containing 30 2.31311
LMNTD1 lamin tail domain containing 1 2.31311
UTF1 undifferentiated embryonic cell transcription factor 1 2.31311
GIPC2 GIPC PDZ domain containing family, member 2 2.31311
ELFN1 extracellular leucine-rich repeat and fibronectin type III domain containing 1 2.31311
MINAR1 membrane integral NOTCH2 associated receptor 1 2.31311
PJVK pejvakin 2.31311
ACP4 acid phosphatase 4 2.31311
TMEM272 transmembrane protein 272 2.31311
OR52P1 olfactory receptor family 52 subfamily P member 1 (gene/pseudogene) 2.31311
ANKRD42-DT ANKRD42 divergent transcript 2.31311
CIMIP7 ciliary microtubule inner protein 7 2.31311
SPMAP2L sperm microtubule associated protein 2 like 2.31311
ATOSB atos homolog B 2.31311
GATD3 glutamine amidotransferase class 1 domain containing 3 2.31311
TMEM35A transmembrane protein 35A 2.31311
SLC7A14 solute carrier family 7, member 14 2.31311
RUSF1 RUS family member 1 2.31311
PNMA8A PNMA family member 8A 2.31311
SEPTIN5 septin 5 2.31311
HEXD hexosaminidase D 2.31311
OTULINL OTU deubiquitinase with linear linkage specificity like 2.31311
LOC122539214 Zinc finger protein LOC122539214 2.31311
NOTCH2NLA notch 2 N-terminal like A 2.31311
SPMIP4 sperm microtubule inner protein 4 2.31311
REP15 RAB15 effector protein 2.31311
TAS2R31 taste receptor, type 2, member 31 2.31311
IRF1 interferon regulatory factor 1 2.31311
FAM43A family with sequence similarity 43, member A 2.31311
PRRG4 proline rich Gla (G-carboxyglutamic acid) 4 (transmembrane) 2.31311
CBLN1 cerebellin 1 precursor 2.31311
TMEM234 transmembrane protein 234 2.31311
STYK1 serine/threonine/tyrosine kinase 1 2.31311
DTX3 deltex 3, E3 ubiquitin ligase 2.31311
CGREF1 cell growth regulator with EF-hand domain 1 2.31311
MBD6 methyl-CpG binding domain protein 6 2.31311
ACHE acetylcholinesterase (Yt blood group) 2.31311
MTNR1A melatonin receptor 1A 2.31311
ST8SIA3 ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransferase 3 2.31311
PTPRR protein tyrosine phosphatase, receptor type, R 2.31311
NKX3-1 NK3 homeobox 1 2.31311
SPSB1 splA/ryanodine receptor domain and SOCS box containing 1 2.31311
ATP13A4 ATPase type 13A4 2.31311
PCDHGA10 protocadherin gamma subfamily A, 10 2.31311
CATSPERQ catsper channel auxiliary subunit theta 2.31311
SCRG1 stimulator of chondrogenesis 1 2.31311
DRAXIN dorsal inhibitory axon guidance protein 2.31311
LCTL lactase-like 2.31311
TOE1 target of EGR1, member 1 (nuclear) 2.31311
PNPLA8 patatin-like phospholipase domain containing 8 2.31311
GDF3 growth differentiation factor 3 2.31311
CCDC102A coiled-coil domain containing 102A 2.31311
COX8C cytochrome c oxidase subunit VIIIC 2.31311
RFXANK regulatory factor X-associated ankyrin-containing protein 2.31311
ZBTB21 zinc finger and BTB domain containing 21 2.31311
KIFAP3 kinesin-associated protein 3 2.31311
CP ceruloplasmin (ferroxidase) 2.31311
PPOX protoporphyrinogen oxidase 2.31311
FIZ1 FLT3-interacting zinc finger 1 2.31311
SMIM10L2A small integral membrane protein 10 like 2A 2.31311
PDE1A phosphodiesterase 1A, calmodulin-dependent 2.31311
ADGRB1 adhesion G protein-coupled receptor B1 2.31311
ADGRB2 adhesion G protein-coupled receptor B2 2.31311
GMPR guanosine monophosphate reductase 2.31311
SLC10A1 solute carrier family 10 (sodium/bile acid cotransporter), member 1 2.31311
HSF2BP heat shock transcription factor 2 binding protein 2.31311
SBSN suprabasin 2.31311
HSH2D hematopoietic SH2 domain containing 2.31311
XG Xg blood group 2.31311
HSPA1L heat shock 70kDa protein 1-like 2.31311
TADA2B transcriptional adaptor 2B 2.31311
MAPKBP1 mitogen-activated protein kinase binding protein 1 2.31311
C12ORF60 chromosome 12 open reading frame 60 2.31311
PRSS3 protease, serine, 3 2.31311
AQP3 aquaporin 3 (Gill blood group) 2.31311
RGS11 regulator of G-protein signaling 11 2.31311
ZC3H10 zinc finger CCCH-type containing 10 2.31311
SMIM24 small integral membrane protein 24 2.31311
MCAT malonyl CoA:ACP acyltransferase (mitochondrial) 2.31311
LIMCH1 LIM and calponin homology domains 1 2.31311
ENTPD3 ectonucleoside triphosphate diphosphohydrolase 3 2.31311
GABRR3 gamma-aminobutyric acid (GABA) A receptor, rho 3 (gene/pseudogene) 2.31311
PROSER2 proline and serine rich 2 2.31311
SLC6A11 solute carrier family 6 (neurotransmitter transporter), member 11 2.31311
WFDC1 WAP four-disulfide core domain 1 2.31311
ENOX1 ecto-NOX disulfide-thiol exchanger 1 2.31311
JAK3 Janus kinase 3 2.31311
PAMR1 peptidase domain containing associated with muscle regeneration 1 2.31311
TCEA3 transcription elongation factor A (SII), 3 2.31311
SRRM5 serine/arginine repetitive matrix 5 2.31311
TMEM52 transmembrane protein 52 2.31311
WDR72 WD repeat domain 72 2.31311
ZFP69 ZFP69 zinc finger protein 2.31311
ACSM1 acyl-CoA synthetase medium-chain family member 1 2.31311
ACSM3 acyl-CoA synthetase medium-chain family member 3 2.31311
FZD4 frizzled class receptor 4 2.31311
AMFR autocrine motility factor receptor, E3 ubiquitin protein ligase 2.31311
SLC24A1 solute carrier family 24 (sodium/potassium/calcium exchanger), member 1 2.31311
ELN elastin 2.31311
TMEM150C transmembrane protein 150C 2.31311
ATP6V0A4 ATPase, H+ transporting, lysosomal V0 subunit a4 2.31311
NANP N-acetylneuraminic acid phosphatase 2.31311
NDFIP2 Nedd4 family interacting protein 2 2.31311
CCDC88B coiled-coil domain containing 88B 2.31311
HS3ST1 heparan sulfate (glucosamine) 3-O-sulfotransferase 1 2.31311
NBPF9 neuroblastoma breakpoint family, member 9 2.31311
CMTM1 CKLF-like MARVEL transmembrane domain containing 1 2.31311
ONECUT1 one cut homeobox 1 2.31311
BCKDK branched chain ketoacid dehydrogenase kinase 2.31311
TMCC2 transmembrane and coiled-coil domain family 2 2.31311
ILF2 interleukin enhancer binding factor 2 2.31311
KCNA2 potassium channel, voltage gated shaker related subfamily A, member 2 2.31311
RASA4 RAS p21 protein activator 4 2.31311
CALY calcyon neuron-specific vesicular protein 2.31311
DCX doublecortin 2.31311
LYPD1 LY6/PLAUR domain containing 1 2.31311
BCL2L10 BCL2-like 10 (apoptosis facilitator) 2.31311
LHX8 LIM homeobox 8 2.31311
C14ORF119 chromosome 14 open reading frame 119 2.31311
PDE11A phosphodiesterase 11A 2.31311
PTCH1 patched 1 2.31311
LY6G6C lymphocyte antigen 6 complex, locus G6C 2.31311
ENTPD6 ectonucleoside triphosphate diphosphohydrolase 6 (putative) 2.31311
DDIT3 DNA-damage-inducible transcript 3 2.31311
ZNF837 zinc finger protein 837 2.31311
RAB33A RAB33A, member RAS oncogene family 2.31311
SYT3 synaptotagmin III 2.31311
SYT7 synaptotagmin VII 2.31311
DEXI Dexi homolog (mouse) 2.31311
DAPL1 death associated protein-like 1 2.31311
CTSK cathepsin K 2.31311
MAP6 microtubule-associated protein 6 2.31311
HLA-DQA1 major histocompatibility complex, class II, DQ alpha 1 2.31311
CCDC106 coiled-coil domain containing 106 2.31311
KLK4 kallikrein-related peptidase 4 2.31311
GALNS galactosamine (N-acetyl)-6-sulfatase 2.31311
NID2 nidogen 2 (osteonidogen) 2.31311
NFKB2 nuclear factor of kappa light polypeptide gene enhancer in B-cells 2 (p49/p100) 2.31311
CCDC73 coiled-coil domain containing 73 2.31311
ZNF276 zinc finger protein 276 2.31311
GADD45B growth arrest and DNA-damage-inducible, beta 2.31311
GPR61 G protein-coupled receptor 61 2.31311
STRA6 stimulated by retinoic acid 6 2.31311
SCUBE3 signal peptide, CUB domain, EGF-like 3 2.31311
SMIM18 small integral membrane protein 18 2.31311
EPHA7 EPH receptor A7 2.31311
IGSF6 immunoglobulin superfamily, member 6 2.31311
USP35 ubiquitin specific peptidase 35 2.31311
ABCB9 ATP-binding cassette, sub-family B (MDR/TAP), member 9 2.31311
SPATA45 spermatogenesis associated 45 2.31311
TOMM20 translocase of outer mitochondrial membrane 20 homolog (yeast) 2.31311
ARHGEF25 Rho guanine nucleotide exchange factor (GEF) 25 2.31311
NTNG2 netrin G2 2.31311
OSMR oncostatin M receptor 2.31311
TBXAS1 thromboxane A synthase 1 (platelet) 2.31311
NBEAL2 neurobeachin-like 2 2.31311
ITIH2 inter-alpha-trypsin inhibitor heavy chain 2 2.31311
ITIH4 inter-alpha-trypsin inhibitor heavy chain family, member 4 2.31311
GRIK1 glutamate receptor, ionotropic, kainate 1 2.31311
CSNK2A3 casein kinase 2, alpha 3 polypeptide 2.31311
PYGM phosphorylase, glycogen, muscle 2.31311
FOXO6 forkhead box O6 2.31311
AGPAT3 1-acylglycerol-3-phosphate O-acyltransferase 3 2.31311
CLCNKA chloride channel, voltage-sensitive Ka 2.31311
PGBD2 piggyBac transposable element derived 2 2.31311
BMP7 bone morphogenetic protein 7 2.31311
CRELD1 cysteine-rich with EGF-like domains 1 2.31311
SELENBP1 selenium binding protein 1 2.31311
ZNF568 zinc finger protein 568 2.31311
MAST3 microtubule associated serine/threonine kinase 3 2.31311
GMPPA GDP-mannose pyrophosphorylase A 2.31311
ZNF30 zinc finger protein 30 2.31311
MAP3K5 mitogen-activated protein kinase kinase kinase 5 2.31311
RUMY2 RUMY family member 2 2.31311
RHOB ras homolog family member B 2.31311
BSPRY B-box and SPRY domain containing 2.31311
DCLRE1A DNA cross-link repair 1A 2.31311
RHOV ras homolog family member V 2.31311
MAFB v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog B 2.31311
PLCE1 phospholipase C, epsilon 1 2.31311
SLIT1 slit homolog 1 (Drosophila) 2.31311
GPRASP1 G protein-coupled receptor associated sorting protein 1 2.31311
METTL16 methyltransferase like 16 2.31311
DGAT1 diacylglycerol O-acyltransferase 1 2.31311
MTURN maturin, neural progenitor differentiation regulator homolog (Xenopus) 2.31311
MPL MPL proto-oncogene, thrombopoietin receptor 2.31311
RHOU ras homolog family member U 2.31311
POU3F1 POU class 3 homeobox 1 2.31311
DDX27 DEAD (Asp-Glu-Ala-Asp) box polypeptide 27 2.31311
SCN3B sodium channel, voltage gated, type III beta subunit 2.31311
F13A1 coagulation factor XIII, A1 polypeptide 2.31311
SLITRK5 SLIT and NTRK-like family, member 5 2.31311
PTK6 protein tyrosine kinase 6 2.31311
CDK15 cyclin-dependent kinase 15 2.31311
CHRM4 cholinergic receptor, muscarinic 4 2.31311
SMG9 SMG9 nonsense mediated mRNA decay factor 2.31311
POTEJ POTE ankyrin domain family, member J 2.31311
MMP21 matrix metallopeptidase 21 2.31311
FSTL3 follistatin-like 3 (secreted glycoprotein) 2.31311
RASL12 RAS-like, family 12 2.31311
CDC50B cell division cycle 50 P4-ATPase accessory subunit B 2.31311
PAOX polyamine oxidase (exo-N4-amino) 2.31311
COCH cochlin 2.31311
ADH4 alcohol dehydrogenase 4 (class II), pi polypeptide 2.31311
SULT1C2 sulfotransferase family, cytosolic, 1C, member 2 2.31311
CCDC74A coiled-coil domain containing 74A 2.31311
C4ORF33 chromosome 4 open reading frame 33 2.31311
ACOT12 acyl-CoA thioesterase 12 2.31311
TICAM2 toll-like receptor adaptor molecule 2 2.31311
CCDC88C coiled-coil domain containing 88C 2.31131
ZWILCH zwilch kinetochore protein 2.31131
STRN4 striatin, calmodulin binding protein 4 2.31131
TMEM219 transmembrane protein 219 2.31131
USP37 ubiquitin specific peptidase 37 2.31131
PUS7 pseudouridylate synthase 7 (putative) 2.30818
CD2AP CD2-associated protein 2.30161
SCUBE1 signal peptide, CUB domain, EGF-like 1 2.29894
USHBP1 Usher syndrome 1C binding protein 1 2.29894
GATAD2B GATA zinc finger domain containing 2B 2.29894
POP1 processing of precursor 1, ribonuclease P/MRP subunit (S. cerevisiae) 2.29894
NGF nerve growth factor (beta polypeptide) 2.29894
UBE2Z ubiquitin-conjugating enzyme E2Z 2.29729
TRIM24 tripartite motif containing 24 2.29087
SRM spermidine synthase 2.25431
CBFA2T2 core-binding factor, runt domain, alpha subunit 2; translocated to, 2 2.20844
GDI2 GDP dissociation inhibitor 2 2.20736
CHST3 carbohydrate (chondroitin 6) sulfotransferase 3 2.20293
IAPP islet amyloid polypeptide 2.20293
IMPDH1 IMP (inosine 5'-monophosphate) dehydrogenase 1 2.20293
DEGS2 delta(4)-desaturase, sphingolipid 2 2.20293
TMCO4 transmembrane and coiled-coil domains 4 2.20293
FOS FBJ murine osteosarcoma viral oncogene homolog 2.20293
HDAC6 histone deacetylase 6 2.20293
TP53I13 tumor protein p53 inducible protein 13 2.20293
COQ10A coenzyme Q10 homolog A (S. cerevisiae) 2.20293
DNALI1 dynein, axonemal, light intermediate chain 1 2.20293
C2CD4C C2 calcium-dependent domain containing 4C 2.20293
PVR poliovirus receptor 2.20293
CADM4 cell adhesion molecule 4 2.20293
PLAC8L1 PLAC8-like 1 2.19368
C8ORF82 chromosome 8 open reading frame 82 2.19368
PLEKHA2 pleckstrin homology domain containing, family A (phosphoinositide binding specific) member 2 2.19368
KCNJ14 potassium channel, inwardly rectifying subfamily J, member 14 2.19368
IER5 immediate early response 5 2.19368
NFATC3 nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 3 2.19368
KBTBD6 kelch repeat and BTB (POZ) domain containing 6 2.19368
SOCS6 suppressor of cytokine signaling 6 2.19368
ZBED8 zinc finger, BED-type containing 8 2.19368
MXRA7 matrix-remodelling associated 7 2.19368
ZNF621 zinc finger protein 621 2.1801
BLOC1S1 biogenesis of lysosomal organelles complex-1, subunit 1 2.16807
SCNN1A sodium channel, non voltage gated 1 alpha subunit 2.16586
TNPO3 transportin 3 2.14774
SNRPA small nuclear ribonucleoprotein polypeptide A 2.13068
UGCG UDP-glucose ceramide glucosyltransferase 2.11656
AUP1 ancient ubiquitous protein 1 2.10895
SLC22A15 solute carrier family 22, member 15 2.10235
PHF19 PHD finger protein 19 2.0846
TRO trophinin 2.0846
PMEL premelanosome protein 2.0846
ZBTB5 zinc finger and BTB domain containing 5 2.0846
TFE3 transcription factor binding to IGHM enhancer 3 2.0846
GPR158 G protein-coupled receptor 158 2.0846
MRC2 mannose receptor, C type 2 2.0846
SCN5A sodium channel, voltage gated, type V alpha subunit 2.0846
KRI1 KRI1 homolog (S. cerevisiae) 2.0846
DVL2 dishevelled segment polarity protein 2 2.0846
SLC37A1 solute carrier family 37 (glucose-6-phosphate transporter), member 1 2.0846
CDC25B cell division cycle 25B 2.0846
SUPT20H suppressor of Ty 20 homolog (S. cerevisiae) 2.06339
FCGRT Fc fragment of IgG, receptor, transporter, alpha 2.06188
RALA v-ral simian leukemia viral oncogene homolog A (ras related) 2.04908
SNRPE small nuclear ribonucleoprotein polypeptide E 2.04593
ACOT7 acyl-CoA thioesterase 7 2.04429

decreased expression

Symbol Name Standardized Value
GSTO1 glutathione S-transferase omega 1 -2.5389
PCCB propionyl CoA carboxylase, beta polypeptide -2.5389
FAM149B1 family with sequence similarity 149, member B1 -2.5389
NDUFAF5 NADH dehydrogenase (ubiquinone) complex I, assembly factor 5 -2.5389
ZKSCAN5 zinc finger with KRAB and SCAN domains 5 -2.5389
E2F4 E2F transcription factor 4, p107/p130-binding -2.5389
PGLS 6-phosphogluconolactonase -2.5389
SLC24A3 solute carrier family 24 (sodium/potassium/calcium exchanger), member 3 -2.5389
BAX BCL2-associated X protein -2.5389
INTS1 integrator complex subunit 1 -2.5389
HUNK hormonally up-regulated Neu-associated kinase -2.53106
DIPK1B divergent protein kinase domain 1B -2.53106
PLEKHO1 pleckstrin homology domain containing, family O member 1 -2.49911
ADCY5 adenylate cyclase 5 -2.49911
UPRT uracil phosphoribosyltransferase (FUR1) homolog (S. cerevisiae) -2.49911
KLHL28 kelch-like family member 28 -2.49911
ZNF830 zinc finger protein 830 -2.49911
SNX19 sorting nexin 19 -2.49911
SSB Sjogren syndrome antigen B (autoantigen La) -2.48863
CCSER2 coiled-coil serine-rich protein 2 -2.39712
MARVELD3 MARVEL domain containing 3 -2.39712
DERL2 derlin 2 -2.38511
RAD51 RAD51 recombinase -2.38511
WDR6 WD repeat domain 6 -2.34325
RYR3 ryanodine receptor 3 -2.34325
SAAL1 serum amyloid A-like 1 -2.32244
FHDC1 FH2 domain containing 1 -2.31311
UGT8 UDP glycosyltransferase 8 -2.31311
ITM2A integral membrane protein 2A -2.31311
BECN1 beclin 1, autophagy related -2.31311
ZCCHC4 zinc finger, CCHC domain containing 4 -2.31311
IQCK IQ motif containing K -2.31311
KLHL29 kelch-like family member 29 -2.31311
NOP58 NOP58 ribonucleoprotein -2.31311
GMNN geminin, DNA replication inhibitor -2.31311
SLC39A6 solute carrier family 39 (zinc transporter), member 6 -2.31311
FUNDC1 FUN14 domain containing 1 -2.31311
TMEM63B transmembrane protein 63B -2.31311
WDR70 WD repeat domain 70 -2.31311
SF3B4 splicing factor 3b, subunit 4, 49kDa -2.31311
RPS15A ribosomal protein S15a -2.31311
TFB2M transcription factor B2, mitochondrial -2.31311
PDPK1 3-phosphoinositide dependent protein kinase 1 -2.31311
KDSR 3-ketodihydrosphingosine reductase -2.31311
HSPBP1 HSPA (heat shock 70kDa) binding protein, cytoplasmic cochaperone 1 -2.31311
SKA3 spindle and kinetochore associated complex subunit 3 -2.31311
CTSL cathepsin L -2.31311
CEP162 centrosomal protein 162kDa -2.31311
ZC3HC1 zinc finger, C3HC-type containing 1 -2.31311
CEP290 centrosomal protein 290kDa -2.31311
CPEB3 cytoplasmic polyadenylation element binding protein 3 -2.31311
FANCF Fanconi anemia, complementation group F -2.31311
TYW3 tRNA-yW synthesizing protein 3 homolog (S. cerevisiae) -2.31131
GPSM1 G-protein signaling modulator 1 -2.31131
SLC2A8 solute carrier family 2 (facilitated glucose transporter), member 8 -2.31131
NOC4L nucleolar complex associated 4 homolog (S. cerevisiae) -2.31131
VPS26B vacuolar protein sorting 26 homolog B (S. pombe) -2.31131
ARFIP2 ADP-ribosylation factor interacting protein 2 -2.31131
ARRDC3 arrestin domain containing 3 -2.31131
C2 complement component 2 -2.31131
FAM13C family with sequence similarity 13, member C -2.31131
ZNF692 zinc finger protein 692 -2.31131
ZNF691 zinc finger protein 691 -2.31131
SLC43A1 solute carrier family 43 (amino acid system L transporter), member 1 -2.31131
RTL10 retrotransposon Gag like 10 -2.31131
CLBA1 clathrin binding box of aftiphilin containing 1 -2.31131
PRPS2 phosphoribosyl pyrophosphate synthetase 2 -2.31131
RNF135 ring finger protein 135 -2.31131
SLC37A4 solute carrier family 37 (glucose-6-phosphate transporter), member 4 -2.31131
KLF13 Kruppel-like factor 13 -2.31131
DNAAF11 dynein axonemal assembly factor 11 -2.31131
DDX20 DEAD (Asp-Glu-Ala-Asp) box polypeptide 20 -2.31131
NMNAT1 nicotinamide nucleotide adenylyltransferase 1 -2.31131
MTMR10 myotubularin related protein 10 -2.31131
TNFAIP1 tumor necrosis factor, alpha-induced protein 1 (endothelial) -2.31131
MTFR1L mitochondrial fission regulator 1-like -2.31131
PRMT8 protein arginine methyltransferase 8 -2.31131
RILP Rab interacting lysosomal protein -2.31131
ARAP2 ArfGAP with RhoGAP domain, ankyrin repeat and PH domain 2 -2.31131
ADGRE2 adhesion G protein-coupled receptor E2 -2.31131
CEP63 centrosomal protein 63kDa -2.31131
ZNF506 zinc finger protein 506 -2.31131
DNAJC6 DnaJ (Hsp40) homolog, subfamily C, member 6 -2.31131
AKAP5 A kinase (PRKA) anchor protein 5 -2.31131
FGD3 FYVE, RhoGEF and PH domain containing 3 -2.31131
NEXN nexilin (F actin binding protein) -2.31131
NDRG2 NDRG family member 2 -2.31131
PCDHB2 protocadherin beta 2 -2.31131
WFS1 Wolfram syndrome 1 (wolframin) -2.31131
UBXN6 UBX domain protein 6 -2.31131
TMCO6 transmembrane and coiled-coil domains 6 -2.31131
LTBP3 latent transforming growth factor beta binding protein 3 -2.31131
LRRC37A leucine rich repeat containing 37A -2.31131
PRTG protogenin -2.31131
PEX6 peroxisomal biogenesis factor 6 -2.31131
NAGA N-acetylgalactosaminidase, alpha- -2.31131
MAN1B1 mannosidase, alpha, class 1B, member 1 -2.31131
RABL2A RAB, member of RAS oncogene family-like 2A -2.31131
PIGX phosphatidylinositol glycan anchor biosynthesis, class X -2.31131
DMAP1 DNA methyltransferase 1 associated protein 1 -2.31131
ZMAT1 zinc finger, matrin-type 1 -2.31131
SYAP1 synapse associated protein 1 -2.31131
ZNF75D zinc finger protein 75D -2.31131
KIFC2 kinesin family member C2 -2.31131
PLA2G4A phospholipase A2, group IVA (cytosolic, calcium-dependent) -2.31131
RASGEF1C RasGEF domain family, member 1C -2.31131
TMEM169 transmembrane protein 169 -2.31131
ZNF674 zinc finger protein 674 -2.31131
NRN1L neuritin 1-like -2.31131
HSPD1 heat shock 60kDa protein 1 (chaperonin) -2.31131
ACSM6 acyl-CoA synthetase medium-chain family member 6 -2.31131
WDFY3 WD repeat and FYVE domain containing 3 -2.31131
ZP3 zona pellucida glycoprotein 3 (sperm receptor) -2.31131
BAIAP2 BAI1-associated protein 2 -2.31131
LRRN3 leucine rich repeat neuronal 3 -2.31131
BAP1 BRCA1 associated protein-1 (ubiquitin carboxy-terminal hydrolase) -2.31131
KIF16B kinesin family member 16B -2.31131
DNASE1L1 deoxyribonuclease I-like 1 -2.31131
ZNF335 zinc finger protein 335 -2.31131
SH2D4A SH2 domain containing 4A -2.31131
ZNF334 zinc finger protein 334 -2.31131
HSPA14 heat shock 70kDa protein 14 -2.31131
LRRC14 leucine rich repeat containing 14 -2.31131
SCN9A sodium channel, voltage gated, type IX alpha subunit -2.31131
PUS3 pseudouridylate synthase 3 -2.31131
TSPEAR thrombospondin-type laminin G domain and EAR repeats -2.31131
FBXO10 F-box protein 10 -2.31131
PSEN2 presenilin 2 -2.31131
EFEMP1 EGF containing fibulin-like extracellular matrix protein 1 -2.31131
SAYSD1 SAYSVFN motif domain containing 1 -2.31131
BCLAF1 BCL2-associated transcription factor 1 -2.31131
KDF1 keratinocyte differentiation factor 1 -2.31131
CDC42EP2 CDC42 effector protein (Rho GTPase binding) 2 -2.31131
MAFK v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog K -2.31131
AOC2 amine oxidase, copper containing 2 (retina-specific) -2.31131
CLHC1 clathrin heavy chain linker domain containing 1 -2.31131
DCC DCC netrin 1 receptor -2.31131
NCAM1 neural cell adhesion molecule 1 -2.31131
POT1 protection of telomeres 1 -2.31131
IL23A interleukin 23, alpha subunit p19 -2.31131
NINL ninein-like -2.30425
ATP5MF ATP synthase membrane subunit f -2.29894
RBBP9 retinoblastoma binding protein 9 -2.29087
LPCAT4 lysophosphatidylcholine acyltransferase 4 -2.29087
CNEP1R1 CTD nuclear envelope phosphatase 1 regulatory subunit 1 -2.29087
CIBAR1 CBY1 interacting BAR domain containing 1 -2.29087
SPICP3 Spi-C transcription factor pseudogene 3 -2.29087
LRRC23 leucine rich repeat containing 23 -2.29087
CD47 CD47 molecule -2.29087
CHRNA7 cholinergic receptor, nicotinic, alpha 7 (neuronal) -2.29087
SEMA4C sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4C -2.29087
ZNF227 zinc finger protein 227 -2.29087
DONSON downstream neighbor of SON -2.29087
PM20D2 peptidase M20 domain containing 2 -2.29087
TRIP13 thyroid hormone receptor interactor 13 -2.29087
ZNF510 zinc finger protein 510 -2.29087
YJU2B YJU2 splicing factor homolog B -2.29087
SLC12A7 solute carrier family 12 (potassium/chloride transporter), member 7 -2.29087
MTSS2 MTSS I-BAR domain containing 2 -2.29087
SERPING1 serpin peptidase inhibitor, clade G (C1 inhibitor), member 1 -2.29087
RABIF RAB interacting factor -2.29087
ZNF232 zinc finger protein 232 -2.29087
TBC1D12 TBC1 domain family, member 12 -2.29087
SPP1 secreted phosphoprotein 1 -2.29087
POLR3C polymerase (RNA) III (DNA directed) polypeptide C (62kD) -2.29087
SGTB small glutamine-rich tetratricopeptide repeat (TPR)-containing, beta -2.29087
UTP14A UTP14, U3 small nucleolar ribonucleoprotein, homolog A (yeast) -2.29087
KHK ketohexokinase (fructokinase) -2.29087
USH2A Usher syndrome 2A (autosomal recessive, mild) -2.29087
TBC1D22B TBC1 domain family, member 22B -2.29087
VPS39 vacuolar protein sorting 39 homolog (S. cerevisiae) -2.29087
HSCB HscB mitochondrial iron-sulfur cluster co-chaperone -2.29087
IL34 interleukin 34 -2.29087
ARHGAP22 Rho GTPase activating protein 22 -2.29087
USP21 ubiquitin specific peptidase 21 -2.29087
KNSTRN kinetochore-localized astrin/SPAG5 binding protein -2.27541
ALMS1 Alstrom syndrome protein 1 -2.26371
MDH1 malate dehydrogenase 1, NAD (soluble) -2.25114
DPP6 dipeptidyl-peptidase 6 -2.24672
SNX3 sorting nexin 3 -2.20293
LAMA2 laminin, alpha 2 -2.19368
ITPRIP inositol 1,4,5-trisphosphate receptor interacting protein -2.19368
HAUS5 HAUS augmin-like complex, subunit 5 -2.19368
SHLD1 shieldin complex subunit 1 -2.19368
FAM216A family with sequence similarity 216, member A -2.19368
CLK2 CDC-like kinase 2 -2.19368
MICA MHC class I polypeptide-related sequence A -2.19368
LIN7A lin-7 homolog A (C. elegans) -2.19368
DCDC2C doublecortin domain containing 2C -2.19368
PPIL2 peptidylprolyl isomerase (cyclophilin)-like 2 -2.19368
CCDC93 coiled-coil domain containing 93 -2.19368
GABRP gamma-aminobutyric acid (GABA) A receptor, pi -2.19368
ZDHHC18 zinc finger, DHHC-type containing 18 -2.19368
RPS24 ribosomal protein S24 -2.18982
SDHAF3 succinate dehydrogenase complex assembly factor 3 -2.17414
KLHL36 kelch-like family member 36 -2.15769
SLC25A32 solute carrier family 25 (mitochondrial folate carrier), member 32 -2.15769
KDM3A lysine (K)-specific demethylase 3A -2.15769
RNPS1 RNA binding protein S1, serine-rich domain -2.13812
ACOT9 acyl-CoA thioesterase 9 -2.12555
ANXA5 annexin A5 -2.10874
SLC39A11 solute carrier family 39, member 11 -2.10154
COPS6 COP9 signalosome subunit 6 -2.08874
UBE2L3 ubiquitin-conjugating enzyme E2L 3 -2.0846
CNBP CCHC-type zinc finger, nucleic acid binding protein -2.0648
KLF12 Kruppel-like factor 12 -2.04743
EDNRB endothelin receptor type B -2.04593
ZNF664-RFLNA ZNF664-RFLNA readthrough -2.04593
MED6 mediator complex subunit 6 -2.04593
VPS33A vacuolar protein sorting 33 homolog A (S. cerevisiae) -2.04593
CLEC2D C-type lectin domain family 2, member D -2.04593
KRABD4 KRAB domain containing 4 -2.04593
C17ORF75 chromosome 17 open reading frame 75 -2.04593
DHRS12 dehydrogenase/reductase (SDR family) member 12 -2.04593
ERP44 endoplasmic reticulum protein 44 -2.04593
USP1 ubiquitin specific peptidase 1 -2.04593
MAPK1 mitogen-activated protein kinase 1 -2.02652
SLC25A17 solute carrier family 25 (mitochondrial carrier; peroxisomal membrane protein, 34kDa), member 17 -2.01168
PGS1 phosphatidylglycerophosphate synthase 1 -2.01168