SEC62 Gene Set

Dataset Pathway Commons Protein-Protein Interactions
Category physical interactions
Type interacting protein
Description SEC62 homolog (S. cerevisiae)|The Sec61 complex is the central component of the protein translocation apparatus of the endoplasmic reticulum (ER) membrane. The protein encoded by this gene and SEC63 protein are found to be associated with ribosome-free SEC61 complex. It is speculated that Sec61-Sec62-Sec63 may perform post-translational protein translocation into the ER. The Sec61-Sec62-Sec63 complex might also perform the backward transport of ER proteins that are subject to the ubiquitin-proteasome-dependent degradation pathway. The encoded protein is an integral membrane protein located in the rough ER. [provided by RefSeq, Jul 2008] (NCBI Entrez Gene Database, 7095)
External Link http://www.ncbi.nlm.nih.gov/gene/7095
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Genes

40 interacting proteins for SEC62 from the Pathway Commons Protein-Protein Interactions dataset.

Symbol Name
ATL3 atlastin GTPase 3
BCAP31 B-cell receptor-associated protein 31
CIC capicua transcriptional repressor
E2F1 E2F transcription factor 1
EMC1 ER membrane protein complex subunit 1
ENDOD1 endonuclease domain containing 1
ERLEC1 endoplasmic reticulum lectin 1
FLOT1 flotillin 1
GLG1 golgi glycoprotein 1
GLUD1 glutamate dehydrogenase 1
HACD3 3-hydroxyacyl-CoA dehydratase 3
LMAN1 lectin, mannose-binding, 1
MAX MYC associated factor X
MYC v-myc avian myelocytomatosis viral oncogene homolog
NGLY1 N-glycanase 1
PCBD1 pterin-4 alpha-carbinolamine dehydratase/dimerization cofactor of hepatocyte nuclear factor 1 alpha
PGRMC1 progesterone receptor membrane component 1
PHB prohibitin
PHB2 prohibitin 2
PIP4K2A phosphatidylinositol-5-phosphate 4-kinase, type II, alpha
PRKCSH protein kinase C substrate 80K-H
RABGAP1 RAB GTPase activating protein 1
RER1 retention in endoplasmic reticulum sorting receptor 1
RHOC ras homolog family member C
SEC63 SEC63 homolog (S. cerevisiae)
SEL1L sel-1 suppressor of lin-12-like (C. elegans)
SPAG5 sperm associated antigen 5
SPCS2 signal peptidase complex subunit 2 homolog (S. cerevisiae)
SPCS3 signal peptidase complex subunit 3 homolog (S. cerevisiae)
SURF4 surfeit 4
TAF1 TAF1 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 250kDa
TIMM13 translocase of inner mitochondrial membrane 13 homolog (yeast)
TIMM8A translocase of inner mitochondrial membrane 8 homolog A (yeast)
TIMM8B translocase of inner mitochondrial membrane 8 homolog B (yeast)
TMEM38B transmembrane protein 38B
UBC ubiquitin C
UGGT1 UDP-glucose glycoprotein glucosyltransferase 1
VAPA VAMP (vesicle-associated membrane protein)-associated protein A, 33kDa
VTI1A vesicle transport through interaction with t-SNAREs 1A
ZNF24 zinc finger protein 24