SEMA3A Gene Set

Dataset LINCS L1000 CMAP CRISPR Knockout Consensus Signatures
Category transcriptomics
Type gene perturbation
Description sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3A|This gene is a member of the semaphorin family and encodes a protein with an Ig-like C2-type (immunoglobulin-like) domain, a PSI domain and a Sema domain. This secreted protein can function as either a chemorepulsive agent, inhibiting axonal outgrowth, or as a chemoattractive agent, stimulating the growth of apical dendrites. In both cases, the protein is vital for normal neuronal pattern development. Increased expression of this protein is associated with schizophrenia and is seen in a variety of human tumor cell lines. Also, aberrant release of this protein is associated with the progression of Alzheimer's disease. [provided by RefSeq, Jul 2008] (NCBI Entrez Gene Database, 10371)
External Link https://ncbi.nlm.nih.gov/gene/10371
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Genes

499 genes differentially expressed following the SEMA3A gene perturbation from the LINCS L1000 CMAP CRISPR Knockout Consensus Signatures dataset.

increased expression

Symbol Name Standardized Value
SYNGR3 synaptogyrin 3 0.0234856
CD40 CD40 molecule, TNF receptor superfamily member 5 0.0190045
SLC6A8 solute carrier family 6 (neurotransmitter transporter), member 8 0.0160334
PDGFC platelet derived growth factor C 0.0150023
IDO1 indoleamine 2,3-dioxygenase 1 0.0149511
JCHAIN joining chain of multimeric IgA and IgM 0.0146662
CXCL9 chemokine (C-X-C motif) ligand 9 0.0144042
AKR7A2 aldo-keto reductase family 7, member A2 (aflatoxin aldehyde reductase) 0.0142272
FBLN1 fibulin 1 0.0139302
PBX1 pre-B-cell leukemia homeobox 1 0.013904
FGFR3 fibroblast growth factor receptor 3 0.0136917
NEFH neurofilament, heavy polypeptide 0.0136863
AGR2 anterior gradient 2 0.0132771
DNAJA3 DnaJ (Hsp40) homolog, subfamily A, member 3 0.0132453
CPE carboxypeptidase E 0.0132234
BST2 bone marrow stromal cell antigen 2 0.0130931
ID1 inhibitor of DNA binding 1, dominant negative helix-loop-helix protein 0.0129194
PRDX2 peroxiredoxin 2 0.0123451
GBP1 guanylate binding protein 1, interferon-inducible 0.0120946
CXCL11 chemokine (C-X-C motif) ligand 11 0.0117211
SNX10 sorting nexin 10 0.0116124
CHKB choline kinase beta 0.0115502
NELL2 NEL-like 2 (chicken) 0.0114454
PDZD2 PDZ domain containing 2 0.011263
PCP4 Purkinje cell protein 4 0.0112159
LYZ lysozyme 0.0111276
SIDT2 SID1 transmembrane family, member 2 0.0111236
RARRES2 retinoic acid receptor responder (tazarotene induced) 2 0.0109754
ASNS asparagine synthetase (glutamine-hydrolyzing) 0.0108888
GCH1 GTP cyclohydrolase 1 0.0107513
CADM1 cell adhesion molecule 1 0.0107422
PLBD1 phospholipase B domain containing 1 0.0106656
REG3A regenerating islet-derived 3 alpha 0.0105324
CPB1 carboxypeptidase B1 (tissue) 0.0104722
RHOB ras homolog family member B 0.0103799
RRM2 ribonucleotide reductase M2 0.0103214
INSIG1 insulin induced gene 1 0.0102526
NBL1 neuroblastoma 1, DAN family BMP antagonist 0.0102383
TMEM106C transmembrane protein 106C 0.0101648
XK X-linked Kx blood group 0.0101629
SUB1 SUB1 homolog (S. cerevisiae) 0.0101443
KANK2 KN motif and ankyrin repeat domains 2 0.0100961
NXN nucleoredoxin 0.0100939
EPHB2 EPH receptor B2 0.0100646
TMEM106B transmembrane protein 106B 0.0100614
TSPAN13 tetraspanin 13 0.00998841
PACSIN2 protein kinase C and casein kinase substrate in neurons 2 0.00996531
AKR7A3 aldo-keto reductase family 7, member A3 (aflatoxin aldehyde reductase) 0.00993151
EEF1A2 eukaryotic translation elongation factor 1 alpha 2 0.00990251
FZD5 frizzled class receptor 5 0.00980278
FASN fatty acid synthase 0.00977345
ENO2 enolase 2 (gamma, neuronal) 0.00969977
LAMA5 laminin, alpha 5 0.0096947
NID1 nidogen 1 0.00963745
DPYD dihydropyrimidine dehydrogenase 0.00958826
FGL2 fibrinogen-like 2 0.00953137
REG1A regenerating islet-derived 1 alpha 0.00948882
PRUNE1 prune exopolyphosphatase 1 0.009338
PER3 period circadian clock 3 0.00932658
MEIS2 Meis homeobox 2 0.00925779
MCOLN1 mucolipin 1 0.00920107
LTBP1 latent transforming growth factor beta binding protein 1 0.00919189
KLHL23 kelch-like family member 23 0.00916838
PIP5K1B phosphatidylinositol-4-phosphate 5-kinase, type I, beta 0.00907837
FOXF1 forkhead box F1 0.00907217
KCNK3 potassium channel, two pore domain subfamily K, member 3 0.00899181
ADCY3 adenylate cyclase 3 0.0089886
SST somatostatin 0.00896032
SEC23A Sec23 homolog A (S. cerevisiae) 0.00889948
BCAT2 branched chain amino-acid transaminase 2, mitochondrial 0.00888828
CLGN calmegin 0.00882799
UGT2B17 UDP glucuronosyltransferase 2 family, polypeptide B17 0.00880785
GNG10 guanine nucleotide binding protein (G protein), gamma 10 0.0087247
TPSAB1 tryptase alpha/beta 1 0.00871623
CRISPLD2 cysteine-rich secretory protein LCCL domain containing 2 0.00865908
NMU neuromedin U 0.00863689
RERE arginine-glutamic acid dipeptide (RE) repeats 0.00860767
RAD23B RAD23 homolog B (S. cerevisiae) 0.00858856
CST3 cystatin C 0.00857292
PCMTD2 protein-L-isoaspartate (D-aspartate) O-methyltransferase domain containing 2 0.00856394
PLD3 phospholipase D family, member 3 0.0085023
G3BP2 GTPase activating protein (SH3 domain) binding protein 2 0.00848392
AURKB aurora kinase B 0.00842845
SAMSN1 SAM domain, SH3 domain and nuclear localization signals 1 0.0084043
CCNB2 cyclin B2 0.00831917
LMO3 LIM domain only 3 (rhombotin-like 2) 0.00828798
COL4A5 collagen, type IV, alpha 5 0.00826871
FRZB frizzled-related protein 0.00825557
DDHD2 DDHD domain containing 2 0.00824445
IARS2 isoleucyl-tRNA synthetase 2, mitochondrial 0.00823323
KLF11 Kruppel-like factor 11 0.00823002
PRSS1 protease, serine, 1 (trypsin 1) 0.00819568
ARHGEF12 Rho guanine nucleotide exchange factor (GEF) 12 0.00818563
MYH10 myosin, heavy chain 10, non-muscle 0.00817555
DHRS11 dehydrogenase/reductase (SDR family) member 11 0.00814539
EXOSC4 exosome component 4 0.00814303
CXCL10 chemokine (C-X-C motif) ligand 10 0.00811969
CHN2 chimerin 2 0.0081054
SERPINI1 serpin peptidase inhibitor, clade I (neuroserpin), member 1 0.00809727
ENTPD1 ectonucleoside triphosphate diphosphohydrolase 1 0.00807354
ARNT2 aryl-hydrocarbon receptor nuclear translocator 2 0.0080686
CHAC1 ChaC glutathione-specific gamma-glutamylcyclotransferase 1 0.00804082
CD46 CD46 molecule, complement regulatory protein 0.00802716
MMP2 matrix metallopeptidase 2 0.00801086
RNF144A ring finger protein 144A 0.00799967
CDC20 cell division cycle 20 0.00799123
SLC37A4 solute carrier family 37 (glucose-6-phosphate transporter), member 4 0.00798098
ZEB1 zinc finger E-box binding homeobox 1 0.00795582
SSBP2 single-stranded DNA binding protein 2 0.0079402
ATP1A1 ATPase, Na+/K+ transporting, alpha 1 polypeptide 0.00793431
NACC2 NACC family member 2, BEN and BTB (POZ) domain containing 0.0079266
SLC7A8 solute carrier family 7 (amino acid transporter light chain, L system), member 8 0.007914
EPAS1 endothelial PAS domain protein 1 0.00789606
AURKA aurora kinase A 0.00788206
ELOVL6 ELOVL fatty acid elongase 6 0.00786742
TENT4A terminal nucleotidyltransferase 4A 0.00786258
KYAT3 kynurenine aminotransferase 3 0.00785955
PAFAH1B1 platelet-activating factor acetylhydrolase 1b, regulatory subunit 1 (45kDa) 0.00784759
IGF2BP3 insulin-like growth factor 2 mRNA binding protein 3 0.00782967
GLOD4 glyoxalase domain containing 4 0.00782614
OS9 osteosarcoma amplified 9, endoplasmic reticulum lectin 0.00782004
ERLIN2 ER lipid raft associated 2 0.00777261
TNFSF13B tumor necrosis factor (ligand) superfamily, member 13b 0.00776967
DLGAP5 discs, large (Drosophila) homolog-associated protein 5 0.00775059
LAMC1 laminin, gamma 1 (formerly LAMB2) 0.00773754
ACOT7 acyl-CoA thioesterase 7 0.00768411
CFB complement factor B 0.00765315
NPY neuropeptide Y 0.00764048
OLFM1 olfactomedin 1 0.00760696
BSG basigin (Ok blood group) 0.00760202
LAMA4 laminin, alpha 4 0.00758285
CPVL carboxypeptidase, vitellogenic-like 0.0075577
RCAN2 regulator of calcineurin 2 0.00753974
VPS72 vacuolar protein sorting 72 homolog (S. cerevisiae) 0.00752813
SELENBP1 selenium binding protein 1 0.00752562
PPP3CB protein phosphatase 3, catalytic subunit, beta isozyme 0.00750833
IL13RA2 interleukin 13 receptor, alpha 2 0.00749079
CAD carbamoyl-phosphate synthetase 2, aspartate transcarbamylase, and dihydroorotase 0.00747455
TBC1D9 TBC1 domain family, member 9 (with GRAM domain) 0.0074547
HGSNAT heparan-alpha-glucosaminide N-acetyltransferase 0.00744218
MFAP4 microfibrillar-associated protein 4 0.00742221
SMTN smoothelin 0.00742027
SETDB1 SET domain, bifurcated 1 0.00739537
GZMA granzyme A (granzyme 1, cytotoxic T-lymphocyte-associated serine esterase 3) 0.00738082
PTGIS prostaglandin I2 (prostacyclin) synthase 0.00733883
GANAB glucosidase, alpha; neutral AB 0.00733752
LEF1 lymphoid enhancer-binding factor 1 0.00733597
MYO1D myosin ID 0.00732318
CPA1 carboxypeptidase A1 (pancreatic) 0.00727296
GPC3 glypican 3 0.00725393
BCAS3 breast carcinoma amplified sequence 3 0.00725389
PRDX4 peroxiredoxin 4 0.00723039
KIF18B kinesin family member 18B 0.00722909
CLC Charcot-Leyden crystal galectin 0.00721438
GUCY1B3 guanylate cyclase 1, soluble, beta 3 0.00721299
SUCO SUN domain containing ossification factor 0.00718246
AKAP8L A kinase (PRKA) anchor protein 8-like 0.00716897
SORT1 sortilin 1 0.00716101
ELP1 elongator acetyltransferase complex subunit 1 0.00713199
PLN phospholamban 0.00713008
PRC1 protein regulator of cytokinesis 1 0.00712658
PHACTR2 phosphatase and actin regulator 2 0.00712008
LBR lamin B receptor 0.00711043
COLEC12 collectin sub-family member 12 0.0071064
RBM38 RNA binding motif protein 38 0.00709622
TAL1 T-cell acute lymphocytic leukemia 1 0.00708863
FOXN3 forkhead box N3 0.00708113
RACGAP1 Rac GTPase activating protein 1 0.00707302
CSDE1 cold shock domain containing E1, RNA-binding 0.00706479
MARCH8 membrane-associated ring finger (C3HC4) 8, E3 ubiquitin protein ligase 0.00706216
MMD monocyte to macrophage differentiation-associated 0.00705585
RRBP1 ribosome binding protein 1 0.00701506
C1QA complement component 1, q subcomponent, A chain 0.00701121
MORC2 MORC family CW-type zinc finger 2 0.00700545
C8ORF4 chromosome 8 open reading frame 4 0.00699936
NADK NAD kinase 0.00698681
ACO1 aconitase 1, soluble 0.00696143
SMCHD1 structural maintenance of chromosomes flexible hinge domain containing 1 0.00695748
ADAMDEC1 ADAM-like, decysin 1 0.00695153
TMX4 thioredoxin-related transmembrane protein 4 0.00694717
RNASE6 ribonuclease, RNase A family, k6 0.00693073
MS4A4A membrane-spanning 4-domains, subfamily A, member 4A 0.00691586
COL9A2 collagen, type IX, alpha 2 0.00691586
FGFR2 fibroblast growth factor receptor 2 0.00690934
CACNA2D2 calcium channel, voltage-dependent, alpha 2/delta subunit 2 0.00690191
L1CAM L1 cell adhesion molecule 0.00689625
SLC24A3 solute carrier family 24 (sodium/potassium/calcium exchanger), member 3 0.00688434
TIA1 TIA1 cytotoxic granule-associated RNA binding protein 0.00686042
RNF38 ring finger protein 38 0.00685711
RHOBTB3 Rho-related BTB domain containing 3 0.00684587
PSRC1 proline/serine-rich coiled-coil 1 0.00684158
FKBP1B FK506 binding protein 1B, 12.6 kDa 0.00683542
MECOM MDS1 and EVI1 complex locus 0.00682579
FLNA filamin A, alpha 0.00681559
DMXL2 Dmx-like 2 0.00681424
PLA2G4A phospholipase A2, group IVA (cytosolic, calcium-dependent) 0.00680936
IMPA2 inositol(myo)-1(or 4)-monophosphatase 2 0.00679531
WARS1 tryptophanyl-tRNA synthetase 1 0.00677344
LPCAT1 lysophosphatidylcholine acyltransferase 1 0.00674932
NINL ninein-like 0.00671714
ABCC4 ATP-binding cassette, sub-family C (CFTR/MRP), member 4 0.00671558
REG1B regenerating islet-derived 1 beta 0.00671036
PLXNB2 plexin B2 0.00670223
CSRP3 cysteine and glycine-rich protein 3 (cardiac LIM protein) 0.00669728
KIF1B kinesin family member 1B 0.00666808
TFAP2A transcription factor AP-2 alpha (activating enhancer binding protein 2 alpha) 0.00666364
NPC1 Niemann-Pick disease, type C1 0.0066563
ECHDC2 enoyl CoA hydratase domain containing 2 0.00665575
TAF15 TAF15 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 68kDa 0.00664279
DVL1 dishevelled segment polarity protein 1 0.00662017
C2CD5 C2 calcium-dependent domain containing 5 0.0066122
GSTM3 glutathione S-transferase mu 3 (brain) 0.0066016
MRTFB myocardin related transcription factor B 0.00658865
BTN3A3 butyrophilin, subfamily 3, member A3 0.00657776
SLC35E2B solute carrier family 35, member E2B 0.00657638
TSPYL4 TSPY-like 4 0.0065605
PIEZO1 piezo-type mechanosensitive ion channel component 1 0.00655333
LSM5 LSM5 homolog, U6 small nuclear RNA associated (S. cerevisiae) 0.00654905
GSE1 Gse1 coiled-coil protein 0.00654733
CBX3 chromobox homolog 3 0.00654624
FANCL Fanconi anemia, complementation group L 0.0065337
ARG2 arginase 2 0.0065273
HIC2 hypermethylated in cancer 2 0.00652612
DYNLL1 dynein, light chain, LC8-type 1 0.00651401
ADGRG6 adhesion G protein-coupled receptor G6 0.0065098
TGFB1 transforming growth factor, beta 1 0.00649823
FABP1 fatty acid binding protein 1, liver 0.00648878
SMG7 SMG7 nonsense mediated mRNA decay factor 0.00648417
PCK1 phosphoenolpyruvate carboxykinase 1 (soluble) 0.00647041
FBXO21 F-box protein 21 0.00646856
SEMA4C sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4C 0.00644554
STXBP6 syntaxin binding protein 6 (amisyn) 0.00643793
CERK ceramide kinase 0.00643156
ASH2L ash2 (absent, small, or homeotic)-like (Drosophila) 0.00642855
PMM2 phosphomannomutase 2 0.00641744
ACSM3 acyl-CoA synthetase medium-chain family member 3 0.006417
ADD1 adducin 1 (alpha) 0.00641576
SLC16A1 solute carrier family 16 (monocarboxylate transporter), member 1 0.00641093
SOCS1 suppressor of cytokine signaling 1 0.00637006
EDNRA endothelin receptor type A 0.00634658
ANKRD17 ankyrin repeat domain 17 0.00634426
ATP2A3 ATPase, Ca++ transporting, ubiquitous 0.00634361
KAT2B K(lysine) acetyltransferase 2B 0.00633567
IFITM1 interferon induced transmembrane protein 1 0.00633056
SMARCA4 SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 4 0.0063284
ALDH1A2 aldehyde dehydrogenase 1 family, member A2 0.00631534
GIMAP4 GTPase, IMAP family member 4 0.00631284
OIP5 Opa interacting protein 5 0.00631104
CEP68 centrosomal protein 68kDa 0.00631069

decreased expression

Symbol Name Standardized Value
ZDHHC6 zinc finger, DHHC-type containing 6 -0.0226452
GABRP gamma-aminobutyric acid (GABA) A receptor, pi -0.0223033
PUF60 poly-U binding splicing factor 60KDa -0.0220565
CXCL8 chemokine (C-X-C motif) ligand 8 -0.0205943
KRT7 keratin 7, type II -0.020062
KRT14 keratin 14, type I -0.0189513
CRYAB crystallin, alpha B -0.01797
TIMM22 translocase of inner mitochondrial membrane 22 homolog (yeast) -0.0172753
FABP7 fatty acid binding protein 7, brain -0.0169581
CSTA cystatin A (stefin A) -0.0167664
KRT5 keratin 5, type II -0.0167457
HSPA1A heat shock 70kDa protein 1A -0.0153082
TACSTD2 tumor-associated calcium signal transducer 2 -0.0152488
DSP desmoplakin -0.0149784
PITX3 paired-like homeodomain 3 -0.0148603
KRT23 keratin 23, type I -0.0142093
AQP3 aquaporin 3 (Gill blood group) -0.0139052
GADD45A growth arrest and DNA-damage-inducible, alpha -0.0138743
KRT17 keratin 17, type I -0.0134924
IPO13 importin 13 -0.0134272
CCN2 cellular communication network factor 2 -0.0132765
MYBPC1 myosin binding protein C, slow type -0.0132429
HTRA1 HtrA serine peptidase 1 -0.0132026
SCGB2A1 secretoglobin, family 2A, member 1 -0.0131327
PERP PERP, TP53 apoptosis effector -0.0131019
LTF lactotransferrin -0.0129922
SLPI secretory leukocyte peptidase inhibitor -0.0128026
APOD apolipoprotein D -0.0127608
DKK1 dickkopf WNT signaling pathway inhibitor 1 -0.0127324
KLF6 Kruppel-like factor 6 -0.0127142
SERPINB5 serpin peptidase inhibitor, clade B (ovalbumin), member 5 -0.0126422
VIM vimentin -0.0125914
CLDN8 claudin 8 -0.0123053
OXTR oxytocin receptor -0.0122758
KRT15 keratin 15, type I -0.0122244
PIP prolactin-induced protein -0.0122231
MMP7 matrix metallopeptidase 7 -0.0121213
TRIM29 tripartite motif containing 29 -0.0119588
EEF1D eukaryotic translation elongation factor 1 delta (guanine nucleotide exchange protein) -0.0119203
PROM1 prominin 1 -0.0118582
PLAAT3 phospholipase A and acyltransferase 3 -0.0117397
OPHN1 oligophrenin 1 -0.0115606
SCD5 stearoyl-CoA desaturase 5 -0.011549
SCGB2A2 secretoglobin, family 2A, member 2 -0.01144
S100A2 S100 calcium binding protein A2 -0.0113642
ANXA1 annexin A1 -0.0113277
EMP1 epithelial membrane protein 1 -0.0112842
EFHD1 EF-hand domain family, member D1 -0.0111607
KHDRBS3 KH domain containing, RNA binding, signal transduction associated 3 -0.0111075
FNDC3B fibronectin type III domain containing 3B -0.010961
TUBB2A tubulin, beta 2A class IIa -0.0108393
S100A11 S100 calcium binding protein A11 -0.0106963
SGK1 serum/glucocorticoid regulated kinase 1 -0.0106601
DOK5 docking protein 5 -0.0106559
PTPRE protein tyrosine phosphatase, receptor type, E -0.010634
UPK1B uroplakin 1B -0.0106167
ANXA2P2 annexin A2 pseudogene 2 -0.0105848
CASP2 caspase 2, apoptosis-related cysteine peptidase -0.0105416
CCL20 chemokine (C-C motif) ligand 20 -0.0104475
CX3CR1 chemokine (C-X3-C motif) receptor 1 -0.0103575
NPIPB3 nuclear pore complex interacting protein family, member B3 -0.0103311
EYA2 EYA transcriptional coactivator and phosphatase 2 -0.010305
AKR1B1 aldo-keto reductase family 1, member B1 (aldose reductase) -0.0102014
FGF1 fibroblast growth factor 1 (acidic) -0.0101846
HMOX1 heme oxygenase 1 -0.0100706
BBOX1 butyrobetaine (gamma), 2-oxoglutarate dioxygenase (gamma-butyrobetaine hydroxylase) 1 -0.0100406
BTG1 B-cell translocation gene 1, anti-proliferative -0.00998347
SAT1 spermidine/spermine N1-acetyltransferase 1 -0.00992076
SCGB1D2 secretoglobin, family 1D, member 2 -0.00977412
PLIN3 perilipin 3 -0.00972564
SPRR3 small proline-rich protein 3 -0.00961895
BAMBI BMP and activin membrane-bound inhibitor -0.00960321
EIF2S3 eukaryotic translation initiation factor 2, subunit 3 gamma, 52kDa -0.00958012
ABLIM1 actin binding LIM protein 1 -0.00953947
BHLHE41 basic helix-loop-helix family, member e41 -0.00953454
IKBKE inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase epsilon -0.00952215
CXADR coxsackie virus and adenovirus receptor -0.00950676
LGALS3 lectin, galactoside-binding, soluble, 3 -0.00946084
TRIP6 thyroid hormone receptor interactor 6 -0.00944911
IQCG IQ motif containing G -0.00942293
NDRG2 NDRG family member 2 -0.00937693
TCF7 transcription factor 7 (T-cell specific, HMG-box) -0.0093433
S100A7 S100 calcium binding protein A7 -0.00934182
GOLT1B golgi transport 1B -0.00929407
PADI2 peptidyl arginine deiminase, type II -0.00924939
CRABP2 cellular retinoic acid binding protein 2 -0.00924123
POPDC3 popeye domain containing 3 -0.00912906
ID4 inhibitor of DNA binding 4, dominant negative helix-loop-helix protein -0.00908667
FCGBP Fc fragment of IgG binding protein -0.0090817
ISG20 interferon stimulated exonuclease gene 20kDa -0.00905476
PMAIP1 phorbol-12-myristate-13-acetate-induced protein 1 -0.0090495
RBM39 RNA binding motif protein 39 -0.00896064
RND3 Rho family GTPase 3 -0.00895754
MME membrane metallo-endopeptidase -0.00893069
LYN LYN proto-oncogene, Src family tyrosine kinase -0.00883907
EIF5A eukaryotic translation initiation factor 5A -0.00880024
ZNF721 zinc finger protein 721 -0.00878122
ADAMTS5 ADAM metallopeptidase with thrombospondin type 1 motif, 5 -0.00875609
CDKN1A cyclin-dependent kinase inhibitor 1A (p21, Cip1) -0.00874071
NEBL nebulette -0.00870884
S100A9 S100 calcium binding protein A9 -0.00869394
UGT2B28 UDP glucuronosyltransferase 2 family, polypeptide B28 -0.00868989
TNC tenascin C -0.00865593
TM4SF1 transmembrane 4 L six family member 1 -0.00862174
GSTP1 glutathione S-transferase pi 1 -0.00860601
RRAGD Ras-related GTP binding D -0.00856133
FOSL1 FOS-like antigen 1 -0.0085519
LITAF lipopolysaccharide-induced TNF factor -0.00848215
SNAI2 snail family zinc finger 2 -0.00843498
PHLDA2 pleckstrin homology-like domain, family A, member 2 -0.00838664
MYOF myoferlin -0.00838646
EGR1 early growth response 1 -0.00836995
CXCL5 chemokine (C-X-C motif) ligand 5 -0.0083419
SWAP70 SWAP switching B-cell complex 70kDa subunit -0.00833969
PMP2 peripheral myelin protein 2 -0.00827965
CLTB clathrin, light chain B -0.0082754
TRAF3IP2 TRAF3 interacting protein 2 -0.00821583
TXN thioredoxin -0.00821574
CCNA2 cyclin A2 -0.00821261
KLK10 kallikrein-related peptidase 10 -0.00820926
SERPINB2 serpin peptidase inhibitor, clade B (ovalbumin), member 2 -0.00816369
PLPP2 phospholipid phosphatase 2 -0.00814966
IER5 immediate early response 5 -0.00812603
ASPH aspartate beta-hydroxylase -0.00809113
EIF3H eukaryotic translation initiation factor 3, subunit H -0.00806261
LPXN leupaxin -0.00802789
CHI3L2 chitinase 3-like 2 -0.00800644
PDCD4 programmed cell death 4 (neoplastic transformation inhibitor) -0.00800131
TCTN2 tectonic family member 2 -0.00800029
TGFA transforming growth factor, alpha -0.00796795
IL1B interleukin 1, beta -0.00794685
AREG amphiregulin -0.00790096
LAT2 linker for activation of T cells family, member 2 -0.00789658
GTF2H3 general transcription factor IIH, polypeptide 3, 34kDa -0.00788086
PDE4B phosphodiesterase 4B, cAMP-specific -0.00786394
EIF6 eukaryotic translation initiation factor 6 -0.0078225
PTHLH parathyroid hormone-like hormone -0.00781909
S100A8 S100 calcium binding protein A8 -0.0077837
ELF3 E74-like factor 3 (ets domain transcription factor, epithelial-specific ) -0.00774971
MAFF v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog F -0.00774599
HOXC6 homeobox C6 -0.00766665
CRABP1 cellular retinoic acid binding protein 1 -0.00766514
AZGP1 alpha-2-glycoprotein 1, zinc-binding -0.00762293
ZNF706 zinc finger protein 706 -0.00761445
PTN pleiotrophin -0.00761289
RASSF1 Ras association (RalGDS/AF-6) domain family member 1 -0.00757239
RSRC2 arginine/serine-rich coiled-coil 2 -0.0075257
MAOB monoamine oxidase B -0.00752264
LAMC2 laminin, gamma 2 -0.00750708
SCPEP1 serine carboxypeptidase 1 -0.00749284
OSTF1 osteoclast stimulating factor 1 -0.00746756
MIA melanoma inhibitory activity -0.00745781
MRPL18 mitochondrial ribosomal protein L18 -0.0074486
CYTL1 cytokine-like 1 -0.00743822
HS3ST1 heparan sulfate (glucosamine) 3-O-sulfotransferase 1 -0.00740832
AZIN1 antizyme inhibitor 1 -0.00738851
YBX3 Y box binding protein 3 -0.00738026
ROPN1B rhophilin associated tail protein 1B -0.00737026
CEACAM1 carcinoembryonic antigen-related cell adhesion molecule 1 (biliary glycoprotein) -0.00736047
SERPINA5 serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 5 -0.0073553
BPIFA1 BPI fold containing family A, member 1 -0.0073516
SSR3 signal sequence receptor, gamma (translocon-associated protein gamma) -0.00735138
CSRP2 cysteine and glycine-rich protein 2 -0.00734098
ZNF160 zinc finger protein 160 -0.00734044
MBL2 mannose-binding lectin (protein C) 2, soluble -0.0072865
MRPS22 mitochondrial ribosomal protein S22 -0.00728468
TTYH1 tweety family member 1 -0.0072762
SELENOT selenoprotein T -0.00727415
AKR1C3 aldo-keto reductase family 1, member C3 -0.00726464
NMB neuromedin B -0.00726226
FHL2 four and a half LIM domains 2 -0.00722433
LCP1 lymphocyte cytosolic protein 1 (L-plastin) -0.00721568
FOXG1 forkhead box G1 -0.0071842
CYC1 cytochrome c-1 -0.00713852
KLF2 Kruppel-like factor 2 -0.00713822
SLC12A2 solute carrier family 12 (sodium/potassium/chloride transporter), member 2 -0.00711421
KRT13 keratin 13, type I -0.00710423
FXYD5 FXYD domain containing ion transport regulator 5 -0.00709207
DDX21 DEAD (Asp-Glu-Ala-Asp) box helicase 21 -0.00707774
SRPX2 sushi-repeat containing protein, X-linked 2 -0.00707372
DAXX death-domain associated protein -0.00706326
CTBP2 C-terminal binding protein 2 -0.00700033
RNF125 ring finger protein 125, E3 ubiquitin protein ligase -0.00699438
FGF9 fibroblast growth factor 9 -0.00699155
TNFRSF10B tumor necrosis factor receptor superfamily, member 10b -0.00698528
SMAGP small cell adhesion glycoprotein -0.00697497
EDN3 endothelin 3 -0.00696986
ARL4C ADP-ribosylation factor-like 4C -0.00695952
TNFAIP3 tumor necrosis factor, alpha-induced protein 3 -0.00694499
C21ORF91 chromosome 21 open reading frame 91 -0.00693834
KRT6A keratin 6A, type II -0.00693815
PGAM1 phosphoglycerate mutase 1 (brain) -0.00693562
SOX10 SRY (sex determining region Y)-box 10 -0.0069205
ARNTL aryl hydrocarbon receptor nuclear translocator-like -0.00691732
GCLM glutamate-cysteine ligase, modifier subunit -0.00690904
ABCG2 ATP-binding cassette, sub-family G (WHITE), member 2 (Junior blood group) -0.00688144
FERMT1 fermitin family member 1 -0.00685658
NFKBIA nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha -0.00684685
KIAA0226L KIAA0226-like -0.00683963
MAB21L1 mab-21-like 1 (C. elegans) -0.00683376
INHBA inhibin, beta A -0.00680681
OLIG2 oligodendrocyte lineage transcription factor 2 -0.00679972
ASCL1 achaete-scute family bHLH transcription factor 1 -0.00679395
KRT19 keratin 19, type I -0.00678962
IFI6 interferon, alpha-inducible protein 6 -0.00678543
HIST1H2BD histone cluster 1, H2bd -0.00677476
MXI1 MAX interactor 1, dimerization protein -0.00676438
TIMP4 TIMP metallopeptidase inhibitor 4 -0.00676028
ACTA2 actin, alpha 2, smooth muscle, aorta -0.00674709
RPL14 ribosomal protein L14 -0.00673203
LHPP phospholysine phosphohistidine inorganic pyrophosphate phosphatase -0.00673165
SYNE3 spectrin repeat containing, nuclear envelope family member 3 -0.00672622
CTSD cathepsin D -0.00671484
PPP1R14B protein phosphatase 1, regulatory (inhibitor) subunit 14B -0.00670474
CEMIP cell migration inducing protein, hyaluronan binding -0.00669582
SORBS2 sorbin and SH3 domain containing 2 -0.00669397
GLA galactosidase, alpha -0.00667169
ATP5F1C ATP synthase F1 subunit gamma -0.00665542
PLEKHS1 pleckstrin homology domain containing, family S member 1 -0.00662943
HOXC10 homeobox C10 -0.00661601
HAUS2 HAUS augmin-like complex, subunit 2 -0.00661524
MVP major vault protein -0.00660806
F3 coagulation factor III (thromboplastin, tissue factor) -0.00659682
COX7A1 cytochrome c oxidase subunit VIIa polypeptide 1 (muscle) -0.00659237
BAALC brain and acute leukemia, cytoplasmic -0.00658975
CDK7 cyclin-dependent kinase 7 -0.00658825
POLG2 polymerase (DNA directed), gamma 2, accessory subunit -0.00657056
ELF5 E74-like factor 5 (ets domain transcription factor) -0.00656802
HOMER1 homer scaffolding protein 1 -0.00656727
LY6D lymphocyte antigen 6 complex, locus D -0.00654856
PFKP phosphofructokinase, platelet -0.00653481
PRDX3 peroxiredoxin 3 -0.00652904
CTNNB1 catenin (cadherin-associated protein), beta 1, 88kDa -0.00651286
TCN1 transcobalamin I (vitamin B12 binding protein, R binder family) -0.00650463
GAPDH glyceraldehyde-3-phosphate dehydrogenase -0.00648701
CD9 CD9 molecule -0.00647185
UCHL1 ubiquitin carboxyl-terminal esterase L1 (ubiquitin thiolesterase) -0.00646864
FABP4 fatty acid binding protein 4, adipocyte -0.00643039
NINJ1 ninjurin 1 -0.00642963
INHBB inhibin, beta B -0.00642766
CHST7 carbohydrate (N-acetylglucosamine 6-O) sulfotransferase 7 -0.0064235
TBC1D4 TBC1 domain family, member 4 -0.00641327
NCAN neurocan -0.00640293
TSPO translocator protein (18kDa) -0.00638204
MBD2 methyl-CpG binding domain protein 2 -0.0063138
LRP4 low density lipoprotein receptor-related protein 4 -0.00629862
RHCG Rh family, C glycoprotein -0.00629716
RAB8B RAB8B, member RAS oncogene family -0.00629454
SCRG1 stimulator of chondrogenesis 1 -0.00629006
THBS2 thrombospondin 2 -0.0062761