SEMA4D Gene Set

Dataset LINCS L1000 CMAP CRISPR Knockout Consensus Signatures
Category transcriptomics
Type gene perturbation
Description sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4D| (NCBI Entrez Gene Database, 10507)
External Link https://ncbi.nlm.nih.gov/gene/10507
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Genes

499 genes differentially expressed following the SEMA4D gene perturbation from the LINCS L1000 CMAP CRISPR Knockout Consensus Signatures dataset.

increased expression

Symbol Name Standardized Value
SIRT3 sirtuin 3 0.0174096
MAP7 microtubule-associated protein 7 0.0126954
RPS4Y1 ribosomal protein S4, Y-linked 1 0.0119701
KRT14 keratin 14, type I 0.0105014
AMDHD2 amidohydrolase domain containing 2 0.00932311
CDH3 cadherin 3, type 1, P-cadherin (placental) 0.00916515
CYP1B1 cytochrome P450, family 1, subfamily B, polypeptide 1 0.00874659
STC2 stanniocalcin 2 0.00866175
PUF60 poly-U binding splicing factor 60KDa 0.00834025
CDH1 cadherin 1, type 1, E-cadherin (epithelial) 0.00824613
IPO13 importin 13 0.00796026
CXCL9 chemokine (C-X-C motif) ligand 9 0.00777559
AKR1C1 aldo-keto reductase family 1, member C1 0.00773363
CCL19 chemokine (C-C motif) ligand 19 0.00760358
SYNGR3 synaptogyrin 3 0.00756453
DSP desmoplakin 0.00755486
MAMLD1 mastermind-like domain containing 1 0.00748848
AKR1C2 aldo-keto reductase family 1, member C2 0.007487
KRT6B keratin 6B, type II 0.00738178
CTBP2 C-terminal binding protein 2 0.0073238
LGR4 leucine-rich repeat containing G protein-coupled receptor 4 0.00731501
MAN2C1 mannosidase, alpha, class 2C, member 1 0.00731388
SERINC5 serine incorporator 5 0.00726622
KRT5 keratin 5, type II 0.00702203
ALDH3A1 aldehyde dehydrogenase 3 family, member A1 0.00686987
GRB14 growth factor receptor-bound protein 14 0.00685353
AKR1C3 aldo-keto reductase family 1, member C3 0.00683407
KRT17 keratin 17, type I 0.00682875
QPCT glutaminyl-peptide cyclotransferase 0.00668541
TACSTD2 tumor-associated calcium signal transducer 2 0.00665474
MTCL1 microtubule crosslinking factor 1 0.00660272
KRT15 keratin 15, type I 0.00659285
KRT6A keratin 6A, type II 0.00658997
ARPP19 cAMP-regulated phosphoprotein, 19kDa 0.00656958
HOXC6 homeobox C6 0.00654981
CCN3 cellular communication network factor 3 0.00639729
ANPEP alanyl (membrane) aminopeptidase 0.00631266
TBL1X transducin (beta)-like 1X-linked 0.00622586
KRAS Kirsten rat sarcoma viral oncogene homolog 0.00621854
SQLE squalene epoxidase 0.00615727
GALNT3 polypeptide N-acetylgalactosaminyltransferase 3 0.00615328
LOXL1 lysyl oxidase-like 1 0.00613679
PNN pinin, desmosome associated protein 0.00613375
ALDH1A1 aldehyde dehydrogenase 1 family, member A1 0.00611318
MYO5C myosin VC 0.00608155
SGMS1 sphingomyelin synthase 1 0.0060357
TBC1D9 TBC1 domain family, member 9 (with GRAM domain) 0.00603094
KRT16 keratin 16, type I 0.00602964
P4HTM prolyl 4-hydroxylase, transmembrane (endoplasmic reticulum) 0.00601802
FGF13 fibroblast growth factor 13 0.00601058
CRISP3 cysteine-rich secretory protein 3 0.00599783
PRKCZ protein kinase C, zeta 0.00596541
PDZK1 PDZ domain containing 1 0.00595969
SPRR1B small proline-rich protein 1B 0.00590627
GCLC glutamate-cysteine ligase, catalytic subunit 0.00589765
LEF1 lymphoid enhancer-binding factor 1 0.00583961
PILRB paired immunoglobin-like type 2 receptor beta 0.00583196
PERP PERP, TP53 apoptosis effector 0.00580474
EREG epiregulin 0.0057805
SIAH2 siah E3 ubiquitin protein ligase 2 0.00577124
EML3 echinoderm microtubule associated protein like 3 0.00576813
ACADVL acyl-CoA dehydrogenase, very long chain 0.00576563
PLXNB1 plexin B1 0.00575513
NTRK2 neurotrophic tyrosine kinase, receptor, type 2 0.00571525
NOTCH2NL notch 2 N-terminal like 0.00570283
RUFY3 RUN and FYVE domain containing 3 0.00568625
NEAT1 nuclear paraspeckle assembly transcript 1 (non-protein coding) 0.00568283
CACNA1D calcium channel, voltage-dependent, L type, alpha 1D subunit 0.00566667
ACAP2 ArfGAP with coiled-coil, ankyrin repeat and PH domains 2 0.00563684
CREBZF CREB/ATF bZIP transcription factor 0.0055538
BICD2 bicaudal D homolog 2 (Drosophila) 0.00554224
RAB40B RAB40B, member RAS oncogene family 0.00549019
VAMP1 vesicle-associated membrane protein 1 (synaptobrevin 1) 0.00548313
SNX1 sorting nexin 1 0.0054795
SFI1 Sfi1 homolog, spindle assembly associated (yeast) 0.00545367
ABCC5 ATP-binding cassette, sub-family C (CFTR/MRP), member 5 0.00544756
RDH11 retinol dehydrogenase 11 (all-trans/9-cis/11-cis) 0.00544089
TNC tenascin C 0.0054344
SERPINE2 serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 2 0.0054181
ZNF185 zinc finger protein 185 (LIM domain) 0.00541327
PTGER3 prostaglandin E receptor 3 (subtype EP3) 0.00540014
HSPA4L heat shock 70kDa protein 4-like 0.00538619
OLFML2B olfactomedin-like 2B 0.00537511
PPL periplakin 0.00537095
ABCA2 ATP-binding cassette, sub-family A (ABC1), member 2 0.00536994
CXCL13 chemokine (C-X-C motif) ligand 13 0.00536962
CCNL2 cyclin L2 0.00535961
PCP4 Purkinje cell protein 4 0.00534627
CDS1 CDP-diacylglycerol synthase (phosphatidate cytidylyltransferase) 1 0.00534324
HIP1R huntingtin interacting protein 1 related 0.00531139
C2CD5 C2 calcium-dependent domain containing 5 0.00526245
EFHD2 EF-hand domain family, member D2 0.00524233
NSUN5P1 NOP2/Sun domain family, member 5 pseudogene 1 0.00522434
RHCG Rh family, C glycoprotein 0.00521647
RCBTB1 regulator of chromosome condensation (RCC1) and BTB (POZ) domain containing protein 1 0.00521132
TCF4 transcription factor 4 0.00520983
ESR1 estrogen receptor 1 0.00519535
MNS1 meiosis-specific nuclear structural 1 0.00519103
ARGLU1 arginine and glutamate rich 1 0.00518913
SCRIB scribbled planar cell polarity protein 0.00517402
ETNK1 ethanolamine kinase 1 0.00517344
DCLK1 doublecortin-like kinase 1 0.005169
PTP4A3 protein tyrosine phosphatase type IVA, member 3 0.0051479
SERPINB5 serpin peptidase inhibitor, clade B (ovalbumin), member 5 0.00514653
CKS2 CDC28 protein kinase regulatory subunit 2 0.00514288
EPS8L2 EPS8-like 2 0.00511552
LSS lanosterol synthase (2,3-oxidosqualene-lanosterol cyclase) 0.00511365
IQSEC1 IQ motif and Sec7 domain 1 0.00511103
HNRNPR heterogeneous nuclear ribonucleoprotein R 0.00510452
PLXNC1 plexin C1 0.00508796
RBM47 RNA binding motif protein 47 0.00508518
PRMT3 protein arginine methyltransferase 3 0.00508263
MICU2 mitochondrial calcium uptake 2 0.00507428
NUP210 nucleoporin 210kDa 0.00505798
ARHGEF4 Rho guanine nucleotide exchange factor (GEF) 4 0.00504018
DNAJB14 DnaJ (Hsp40) homolog, subfamily B, member 14 0.00502706
RTN1 reticulon 1 0.00501368
LRIG1 leucine-rich repeats and immunoglobulin-like domains 1 0.00501052
SHMT2 serine hydroxymethyltransferase 2 (mitochondrial) 0.00499838
PKP3 plakophilin 3 0.00498314
MAGED1 melanoma antigen family D1 0.00497551
VCAM1 vascular cell adhesion molecule 1 0.00495395
KRT81 keratin 81, type II 0.00494445
GPR88 G protein-coupled receptor 88 0.00493529
CLCA2 chloride channel accessory 2 0.00492498
ENPP2 ectonucleotide pyrophosphatase/phosphodiesterase 2 0.00491639
MAP4K3 mitogen-activated protein kinase kinase kinase kinase 3 0.00490672
GOLGA8A golgin A8 family, member A 0.00490384
SERPINB4 serpin peptidase inhibitor, clade B (ovalbumin), member 4 0.00488049
PPFIA1 protein tyrosine phosphatase, receptor type, f polypeptide (PTPRF), interacting protein (liprin), alpha 1 0.0048728
YBX3 Y box binding protein 3 0.00486423
TNFRSF25 tumor necrosis factor receptor superfamily, member 25 0.0048631
USP32P2 ubiquitin specific peptidase 32 pseudogene 2 0.00486229
IGHMBP2 immunoglobulin mu binding protein 2 0.00484262
EPCAM epithelial cell adhesion molecule 0.00482978
KLK5 kallikrein-related peptidase 5 0.00482474
DVL1 dishevelled segment polarity protein 1 0.00481642
SLC39A6 solute carrier family 39 (zinc transporter), member 6 0.00480202
SERPINB3 serpin peptidase inhibitor, clade B (ovalbumin), member 3 0.00479299
CD151 CD151 molecule (Raph blood group) 0.00478359
RAD9A RAD9 homolog A (S. pombe) 0.00478303
PPBP pro-platelet basic protein (chemokine (C-X-C motif) ligand 7) 0.00478023
SPAG1 sperm associated antigen 1 0.00477722
TPD52L1 tumor protein D52-like 1 0.00477465
IRX5 iroquois homeobox 5 0.00476971
MET MET proto-oncogene, receptor tyrosine kinase 0.00476023
PAQR6 progestin and adipoQ receptor family member VI 0.00475991
ELP1 elongator acetyltransferase complex subunit 1 0.0047425
CLCN7 chloride channel, voltage-sensitive 7 0.0047327
SIGIRR single immunoglobulin and toll-interleukin 1 receptor (TIR) domain 0.0047266
CCZ1B CCZ1 vacuolar protein trafficking and biogenesis associated homolog B (S. cerevisiae) 0.00472461
ADCY1 adenylate cyclase 1 (brain) 0.00470751
C2CD2 C2 calcium-dependent domain containing 2 0.00470066
LUC7L3 LUC7-like 3 (S. cerevisiae) 0.00469638
TP63 tumor protein p63 0.00468857
PGD phosphogluconate dehydrogenase 0.00467758
GREB1 growth regulation by estrogen in breast cancer 1 0.00467635
XCL1 chemokine (C motif) ligand 1 0.00466484
POLG2 polymerase (DNA directed), gamma 2, accessory subunit 0.00464761
TNK2 tyrosine kinase, non-receptor, 2 0.00461667
SYNE3 spectrin repeat containing, nuclear envelope family member 3 0.00458752
H1-0 H1.0 linker histone 0.00458
BASP1 brain abundant, membrane attached signal protein 1 0.00456848
TARDBP TAR DNA binding protein 0.00456758
KCNN2 potassium channel, calcium activated intermediate/small conductance subfamily N alpha, member 2 0.00456566
FAAH fatty acid amide hydrolase 0.00456261
CLGN calmegin 0.00455988
ANKRD10 ankyrin repeat domain 10 0.00455441
TSPYL5 TSPY-like 5 0.00454944
DEAF1 DEAF1 transcription factor 0.00454072
SACM1L SAC1 suppressor of actin mutations 1-like (yeast) 0.00453294
CSTA cystatin A (stefin A) 0.00452581
RPL10 ribosomal protein L10 0.004511
ENTPD4 ectonucleoside triphosphate diphosphohydrolase 4 0.00449846
APOBEC3B apolipoprotein B mRNA editing enzyme, catalytic polypeptide-like 3B 0.00449739
RESF1 retroelement silencing factor 1 0.00449539
SCGB1D2 secretoglobin, family 1D, member 2 0.00449423
RSRP1 arginine/serine-rich protein 1 0.00448589
PIDD1 p53-induced death domain protein 1 0.00447811
DNMT1 DNA (cytosine-5-)-methyltransferase 1 0.00446579
NACC2 NACC family member 2, BEN and BTB (POZ) domain containing 0.00446242
DMXL2 Dmx-like 2 0.00446024
CST6 cystatin E/M 0.00445721
ANTKMT adenine nucleotide translocase lysine methyltransferase 0.00445537
ARID1A AT rich interactive domain 1A (SWI-like) 0.00444465
EHBP1L1 EH domain binding protein 1-like 1 0.00443391
CAMKK2 calcium/calmodulin-dependent protein kinase kinase 2, beta 0.0044303
CROCCP2 ciliary rootlet coiled-coil, rootletin pseudogene 2 0.00441914
SGSM2 small G protein signaling modulator 2 0.00440776
GZMB granzyme B (granzyme 2, cytotoxic T-lymphocyte-associated serine esterase 1) 0.00439215
MGAT4B mannosyl (alpha-1,3-)-glycoprotein beta-1,4-N-acetylglucosaminyltransferase, isozyme B 0.00439203
ANO3 anoctamin 3 0.0043845
NPR3 natriuretic peptide receptor 3 0.00438191
SERPINI1 serpin peptidase inhibitor, clade I (neuroserpin), member 1 0.00438016
FGFR3 fibroblast growth factor receptor 3 0.00437793
MACROD1 MACRO domain containing 1 0.0043688
SH3GLB2 SH3-domain GRB2-like endophilin B2 0.00436858
DHCR7 7-dehydrocholesterol reductase 0.00435942
TBC1D9B TBC1 domain family, member 9B (with GRAM domain) 0.00435717
NKTR natural killer cell triggering receptor 0.00435542
TNS3 tensin 3 0.004354
SPATA20 spermatogenesis associated 20 0.00435116
SPG7 spastic paraplegia 7 (pure and complicated autosomal recessive) 0.00434887
KLK2 kallikrein-related peptidase 2 0.00434286
LTF lactotransferrin 0.00432842
CTBP1 C-terminal binding protein 1 0.00432288
TMEM80 transmembrane protein 80 0.00431098
TSC2 tuberous sclerosis 2 0.00430672
DDX11 DEAD/H (Asp-Glu-Ala-Asp/His) box helicase 11 0.00430065
PLPP2 phospholipid phosphatase 2 0.0042953
GPR87 G protein-coupled receptor 87 0.00429275
COL4A3 collagen, type IV, alpha 3 (Goodpasture antigen) 0.00428019
TIMELESS timeless circadian clock 0.00427825
NPY neuropeptide Y 0.00426995
KAZN kazrin, periplakin interacting protein 0.0042617
BCL2L1 BCL2-like 1 0.00426032
MSMB microseminoprotein, beta- 0.00424979
MCTP2 multiple C2 domains, transmembrane 2 0.00424825
POMT1 protein-O-mannosyltransferase 1 0.00424529
RAB38 RAB38, member RAS oncogene family 0.00424454
MXD4 MAX dimerization protein 4 0.00423974
ANO1 anoctamin 1, calcium activated chloride channel 0.00423616
AHR aryl hydrocarbon receptor 0.00423258
ZZEF1 zinc finger, ZZ-type with EF-hand domain 1 0.00423209
MAEA macrophage erythroblast attacher 0.00422644
DNAJC6 DnaJ (Hsp40) homolog, subfamily C, member 6 0.0042207
MBTPS1 membrane-bound transcription factor peptidase, site 1 0.00421966
HPN hepsin 0.00421732
PPM1B protein phosphatase, Mg2+/Mn2+ dependent, 1B 0.00420362
CDK5RAP2 CDK5 regulatory subunit associated protein 2 0.00419827
NAA40 N(alpha)-acetyltransferase 40, NatD catalytic subunit 0.00419102
SPOCK1 sparc/osteonectin, cwcv and kazal-like domains proteoglycan (testican) 1 0.00418591
S100A12 S100 calcium binding protein A12 0.00418432
BCR breakpoint cluster region 0.00417182
PLXND1 plexin D1 0.00417072
PLCB3 phospholipase C, beta 3 (phosphatidylinositol-specific) 0.00416788
AREG amphiregulin 0.00416671
MARCH8 membrane-associated ring finger (C3HC4) 8, E3 ubiquitin protein ligase 0.00416495
HTATIP2 HIV-1 Tat interactive protein 2, 30kDa 0.00415763
WWC3 WWC family member 3 0.00415705
ASXL1 additional sex combs like transcriptional regulator 1 0.00414805
SERPINA1 serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 1 0.0041445
CPOX coproporphyrinogen oxidase 0.00413397
PAWR PRKC, apoptosis, WT1, regulator 0.00412859
SCAF4 SR-related CTD-associated factor 4 0.00412644
PCYT2 phosphate cytidylyltransferase 2, ethanolamine 0.00411793
CPSF1 cleavage and polyadenylation specific factor 1, 160kDa 0.00411766
FAT2 FAT atypical cadherin 2 0.00411663
FAM168B family with sequence similarity 168, member B 0.00411562
STAG2 stromal antigen 2 0.00410101

decreased expression

Symbol Name Standardized Value
IFI6 interferon, alpha-inducible protein 6 -0.0168896
IFI27 interferon, alpha-inducible protein 27 -0.0156426
PLA2G2A phospholipase A2, group IIA (platelets, synovial fluid) -0.0153394
IFIT1 interferon-induced protein with tetratricopeptide repeats 1 -0.0146526
IFI44L interferon-induced protein 44-like -0.013799
MX1 MX dynamin-like GTPase 1 -0.0133131
IFI44 interferon-induced protein 44 -0.0126164
ISG15 ISG15 ubiquitin-like modifier -0.0125188
HERC5 HECT and RLD domain containing E3 ubiquitin protein ligase 5 -0.0112084
OAS2 2'-5'-oligoadenylate synthetase 2, 69/71kDa -0.0110998
TENT5A terminal nucleotidyltransferase 5A -0.0110639
GNAS GNAS complex locus -0.0110217
OAS1 2'-5'-oligoadenylate synthetase 1, 40/46kDa -0.0108106
FCGBP Fc fragment of IgG binding protein -0.0104305
CXCL14 chemokine (C-X-C motif) ligand 14 -0.0102891
MBD1 methyl-CpG binding domain protein 1 -0.0102777
CASP10 caspase 10, apoptosis-related cysteine peptidase -0.0102295
LGALS13 lectin, galactoside-binding, soluble, 13 -0.0101124
IFITM1 interferon induced transmembrane protein 1 -0.0100317
IFIT3 interferon-induced protein with tetratricopeptide repeats 3 -0.00965308
EIF5A eukaryotic translation initiation factor 5A -0.00954733
AOC1 amine oxidase, copper containing 1 -0.0095325
MX2 MX dynamin-like GTPase 2 -0.00952091
RSAD2 radical S-adenosyl methionine domain containing 2 -0.00920459
CEBPA CCAAT/enhancer binding protein (C/EBP), alpha -0.00905859
AKAP12 A kinase (PRKA) anchor protein 12 -0.0087677
MT1E metallothionein 1E -0.00868002
CTSS cathepsin S -0.00862585
PITX3 paired-like homeodomain 3 -0.00856842
ACKR3 atypical chemokine receptor 3 -0.00856028
FABP7 fatty acid binding protein 7, brain -0.00852141
SP110 SP110 nuclear body protein -0.00847469
ATF3 activating transcription factor 3 -0.00844602
OLFML3 olfactomedin-like 3 -0.00829456
PLIN2 perilipin 2 -0.00827517
DMBT1 deleted in malignant brain tumors 1 -0.00825844
FAR2 fatty acyl CoA reductase 2 -0.00824744
LPAR6 lysophosphatidic acid receptor 6 -0.0081496
CFI complement factor I -0.00808807
LAMP3 lysosomal-associated membrane protein 3 -0.00801485
GPRC5A G protein-coupled receptor, class C, group 5, member A -0.0079773
XIC X chromosome inactivation center -0.00788435
CCL20 chemokine (C-C motif) ligand 20 -0.00787192
RNASET2 ribonuclease T2 -0.0078047
CHEK2 checkpoint kinase 2 -0.00777949
LCP1 lymphocyte cytosolic protein 1 (L-plastin) -0.00763649
XAF1 XIAP associated factor 1 -0.00758755
NRN1 neuritin 1 -0.00757279
OAS3 2'-5'-oligoadenylate synthetase 3, 100kDa -0.00752645
USP18 ubiquitin specific peptidase 18 -0.00743371
GAP43 growth associated protein 43 -0.0073002
LAPTM5 lysosomal protein transmembrane 5 -0.00728933
MAFF v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog F -0.00724412
CRABP1 cellular retinoic acid binding protein 1 -0.00717637
ADH5 alcohol dehydrogenase 5 (class III), chi polypeptide -0.00713913
PDLIM1 PDZ and LIM domain 1 -0.00713814
ALOX5AP arachidonate 5-lipoxygenase-activating protein -0.0071274
ID4 inhibitor of DNA binding 4, dominant negative helix-loop-helix protein -0.00712173
OASL 2'-5'-oligoadenylate synthetase-like -0.00710093
RTN2 reticulon 2 -0.00704997
ASS1 argininosuccinate synthase 1 -0.00704659
CD53 CD53 molecule -0.0070207
CXADR coxsackie virus and adenovirus receptor -0.00700906
LGALS3BP lectin, galactoside-binding, soluble, 3 binding protein -0.00699332
DCN decorin -0.00698038
MT1F metallothionein 1F -0.00696273
ANXA1 annexin A1 -0.0069445
MEN1 multiple endocrine neoplasia I -0.00694054
C8ORF4 chromosome 8 open reading frame 4 -0.00692328
PTPRO protein tyrosine phosphatase, receptor type, O -0.00690814
AK4 adenylate kinase 4 -0.00686934
ALDH7A1 aldehyde dehydrogenase 7 family, member A1 -0.00684136
EVI2A ecotropic viral integration site 2A -0.00682931
EDN3 endothelin 3 -0.00681511
SLC35G2 solute carrier family 35, member G2 -0.00671555
CSF1 colony stimulating factor 1 (macrophage) -0.00664888
ABCA8 ATP-binding cassette, sub-family A (ABC1), member 8 -0.00656732
ZDHHC6 zinc finger, DHHC-type containing 6 -0.00653983
SAMSN1 SAM domain, SH3 domain and nuclear localization signals 1 -0.00647908
GPX3 glutathione peroxidase 3 -0.00646214
TFPI2 tissue factor pathway inhibitor 2 -0.00645728
GNE glucosamine (UDP-N-acetyl)-2-epimerase/N-acetylmannosamine kinase -0.006433
CSRP2 cysteine and glycine-rich protein 2 -0.00643047
PAPSS2 3'-phosphoadenosine 5'-phosphosulfate synthase 2 -0.00641926
MOXD1 monooxygenase, DBH-like 1 -0.00636804
NEDD9 neural precursor cell expressed, developmentally down-regulated 9 -0.00635492
MAOA monoamine oxidase A -0.00632987
COLEC12 collectin sub-family member 12 -0.00630872
ZG16 zymogen granule protein 16 -0.00630532
GIMAP4 GTPase, IMAP family member 4 -0.00629362
MS4A4A membrane-spanning 4-domains, subfamily A, member 4A -0.00627826
PDPN podoplanin -0.0062508
LGALS9 lectin, galactoside-binding, soluble, 9 -0.00624116
ARHGAP15 Rho GTPase activating protein 15 -0.00621921
LYVE1 lymphatic vessel endothelial hyaluronan receptor 1 -0.00619473
ZFPM2 zinc finger protein, FOG family member 2 -0.006192
VSIG4 V-set and immunoglobulin domain containing 4 -0.00616816
CLCA1 chloride channel accessory 1 -0.00615457
ACP5 acid phosphatase 5, tartrate resistant -0.00613895
TREM2 triggering receptor expressed on myeloid cells 2 -0.00612983
CEACAM1 carcinoembryonic antigen-related cell adhesion molecule 1 (biliary glycoprotein) -0.00612349
C3 complement component 3 -0.00612308
CPE carboxypeptidase E -0.00611343
ATP10B ATPase, class V, type 10B -0.00610468
IFIT5 interferon-induced protein with tetratricopeptide repeats 5 -0.00609724
TMEM176A transmembrane protein 176A -0.00608393
CREM cAMP responsive element modulator -0.00602598
NIBAN1 niban apoptosis regulator 1 -0.00602525
TMEM176B transmembrane protein 176B -0.00602302
BTG3 BTG family, member 3 -0.00602283
HTRA1 HtrA serine peptidase 1 -0.0059788
HDAC9 histone deacetylase 9 -0.00597498
PDZD2 PDZ domain containing 2 -0.00596772
MECOM MDS1 and EVI1 complex locus -0.00592592
HERC6 HECT and RLD domain containing E3 ubiquitin protein ligase family member 6 -0.0059237
CARMIL1 capping protein regulator and myosin 1 linker 1 -0.00587774
SLC39A8 solute carrier family 39 (zinc transporter), member 8 -0.00587208
MT1M metallothionein 1M -0.00586934
CD69 CD69 molecule -0.00586644
GPNMB glycoprotein (transmembrane) nmb -0.00584195
ITGB2 integrin, beta 2 (complement component 3 receptor 3 and 4 subunit) -0.00583832
FHL1 four and a half LIM domains 1 -0.00583556
GPM6B glycoprotein M6B -0.00583126
TUBB2B tubulin, beta 2B class IIb -0.0058125
PDIA3 protein disulfide isomerase family A, member 3 -0.00580988
RNASE1 ribonuclease, RNase A family, 1 (pancreatic) -0.00579729
TGM2 transglutaminase 2 -0.00578929
ITM2A integral membrane protein 2A -0.00578656
MT1G metallothionein 1G -0.00576571
PLAUR plasminogen activator, urokinase receptor -0.00576193
LAMA4 laminin, alpha 4 -0.0057577
FCGR2B Fc fragment of IgG, low affinity IIb, receptor (CD32) -0.00575081
PDE4B phosphodiesterase 4B, cAMP-specific -0.0057247
PSMA7 proteasome (prosome, macropain) subunit, alpha type, 7 -0.00571988
CRELD2 cysteine-rich with EGF-like domains 2 -0.00571108
A2M alpha-2-macroglobulin -0.00570761
MSR1 macrophage scavenger receptor 1 -0.00570564
IFIT2 interferon-induced protein with tetratricopeptide repeats 2 -0.00570481
TYROBP TYRO protein tyrosine kinase binding protein -0.0057004
CASP2 caspase 2, apoptosis-related cysteine peptidase -0.00568201
BEX4 brain expressed, X-linked 4 -0.00568175
C1ORF54 chromosome 1 open reading frame 54 -0.00567132
PTGER4 prostaglandin E receptor 4 (subtype EP4) -0.00566446
HAMP hepcidin antimicrobial peptide -0.00566159
CXCL8 chemokine (C-X-C motif) ligand 8 -0.00565724
GATA6 GATA binding protein 6 -0.0056523
GPX2 glutathione peroxidase 2 -0.00565032
PLN phospholamban -0.00563002
PRKACB protein kinase, cAMP-dependent, catalytic, beta -0.00561709
IFI35 interferon-induced protein 35 -0.00561235
RAB8B RAB8B, member RAS oncogene family -0.00558581
KLF9 Kruppel-like factor 9 -0.00557341
SELENOW selenoprotein W -0.0055686
DLST dihydrolipoamide S-succinyltransferase (E2 component of 2-oxo-glutarate complex) -0.00554175
APOC2 apolipoprotein C-II -0.00554148
CD83 CD83 molecule -0.00553705
DKK3 dickkopf WNT signaling pathway inhibitor 3 -0.00553516
IFI16 interferon, gamma-inducible protein 16 -0.00553071
DHRS9 dehydrogenase/reductase (SDR family) member 9 -0.00551455
MT1HL1 metallothionein 1H-like 1 -0.00551258
FBP1 fructose-1,6-bisphosphatase 1 -0.00547897
FXYD6 FXYD domain containing ion transport regulator 6 -0.0054718
DDX58 DEAD (Asp-Glu-Ala-Asp) box polypeptide 58 -0.00545468
ACTG2 actin, gamma 2, smooth muscle, enteric -0.00545309
ATIC 5-aminoimidazole-4-carboxamide ribonucleotide formyltransferase/IMP cyclohydrolase -0.00544859
RBM34 RNA binding motif protein 34 -0.00544772
MAB21L2 mab-21-like 2 (C. elegans) -0.00544614
SOD3 superoxide dismutase 3, extracellular -0.00543494
RNASE6 ribonuclease, RNase A family, k6 -0.00541208
VWA5A von Willebrand factor A domain containing 5A -0.00540686
BCL2A1 BCL2-related protein A1 -0.00540571
PEG3 paternally expressed 3 -0.00539072
ADORA2B adenosine A2b receptor -0.00538019
ZNF586 zinc finger protein 586 -0.00537223
CALR calreticulin -0.00535502
ZIC1 Zic family member 1 -0.00534098
REEP5 receptor accessory protein 5 -0.00531542
SHFL shiftless antiviral inhibitor of ribosomal frameshifting -0.00530726
CLIC5 chloride intracellular channel 5 -0.00529568
RPL36 ribosomal protein L36 -0.00528535
CITED2 Cbp/p300-interacting transactivator, with Glu/Asp-rich carboxy-terminal domain, 2 -0.00528491
HEATR1 HEAT repeat containing 1 -0.00524207
HEY1 hes-related family bHLH transcription factor with YRPW motif 1 -0.00523927
SLPI secretory leukocyte peptidase inhibitor -0.00523869
DDX60 DEAD (Asp-Glu-Ala-Asp) box polypeptide 60 -0.00522974
LYPD1 LY6/PLAUR domain containing 1 -0.00522822
HNRNPL heterogeneous nuclear ribonucleoprotein L -0.00522682
SAMHD1 SAM domain and HD domain 1 -0.00521913
KIFAP3 kinesin-associated protein 3 -0.00521448
IFIH1 interferon induced with helicase C domain 1 -0.00518292
TMBIM1 transmembrane BAX inhibitor motif containing 1 -0.00518265
ARHGEF6 Rac/Cdc42 guanine nucleotide exchange factor (GEF) 6 -0.00516817
LAMA2 laminin, alpha 2 -0.00516419
PTPRC protein tyrosine phosphatase, receptor type, C -0.00516282
CCRL2 chemokine (C-C motif) receptor-like 2 -0.00515787
COX6B1 cytochrome c oxidase subunit VIb polypeptide 1 (ubiquitous) -0.00515542
MFAP4 microfibrillar-associated protein 4 -0.0051537
DES desmin -0.0051415
HSD17B6 hydroxysteroid (17-beta) dehydrogenase 6 -0.00513906
RARRES2 retinoic acid receptor responder (tazarotene induced) 2 -0.00513875
AXL AXL receptor tyrosine kinase -0.00513367
DPYD dihydropyrimidine dehydrogenase -0.00510834
TRIM36 tripartite motif containing 36 -0.00510459
TAGLN2 transgelin 2 -0.00510022
DOK5 docking protein 5 -0.00509564
ADH1C alcohol dehydrogenase 1C (class I), gamma polypeptide -0.00509481
MS4A6A membrane-spanning 4-domains, subfamily A, member 6A -0.00508208
CCNG1 cyclin G1 -0.00506488
GPX1 glutathione peroxidase 1 -0.00506268
FOLR1 folate receptor 1 (adult) -0.0050414
SLA Src-like-adaptor -0.00504003
PRDX6 peroxiredoxin 6 -0.00503589
TSPAN8 tetraspanin 8 -0.00503033
SSPN sarcospan -0.00502408
SLC4A4 solute carrier family 4 (sodium bicarbonate cotransporter), member 4 -0.0050198
LMO2 LIM domain only 2 (rhombotin-like 1) -0.00501797
MSLN mesothelin -0.00500986
LPXN leupaxin -0.00496789
CHMP5 charged multivesicular body protein 5 -0.00494876
STAC SH3 and cysteine rich domain -0.00494113
SPINK4 serine peptidase inhibitor, Kazal type 4 -0.00492485
ITGA4 integrin, alpha 4 (antigen CD49D, alpha 4 subunit of VLA-4 receptor) -0.00492476
SYNPO synaptopodin -0.0049164
MTUS1 microtubule associated tumor suppressor 1 -0.00490064
TPM4 tropomyosin 4 -0.00489812
FXYD1 FXYD domain containing ion transport regulator 1 -0.00489256
DNAJB9 DnaJ (Hsp40) homolog, subfamily B, member 9 -0.00488401
TMEM59 transmembrane protein 59 -0.00487734
ADH1B alcohol dehydrogenase 1B (class I), beta polypeptide -0.0048765
LRRN3 leucine rich repeat neuronal 3 -0.0048722
RCBTB2 regulator of chromosome condensation (RCC1) and BTB (POZ) domain containing protein 2 -0.00487173
PIPOX pipecolic acid oxidase -0.00486907
ITM2C integral membrane protein 2C -0.00484082
CEMIP cell migration inducing protein, hyaluronan binding -0.00483952
CES1 carboxylesterase 1 -0.0048353
CCL22 chemokine (C-C motif) ligand 22 -0.00483457
PLTP phospholipid transfer protein -0.00481793
LMO3 LIM domain only 3 (rhombotin-like 2) -0.0048162
EIF1 eukaryotic translation initiation factor 1 -0.00481367
CLEC2B C-type lectin domain family 2, member B -0.00480572
EIF2AK2 eukaryotic translation initiation factor 2-alpha kinase 2 -0.00480327
SLN sarcolipin -0.00480239
EPHB2 EPH receptor B2 -0.0047981
DEFA5 defensin, alpha 5, Paneth cell-specific -0.0047864
CA4 carbonic anhydrase IV -0.00478454
IL1R1 interleukin 1 receptor, type I -0.00477389
RPS27L ribosomal protein S27-like -0.00477143
NDRG2 NDRG family member 2 -0.00476871
PNMA2 paraneoplastic Ma antigen 2 -0.0047584