SEPT7 Gene Set

Dataset MSigDB Cancer Gene Co-expression Modules
Category transcriptomics
Type co-expressed gene
Description septin 7|This gene encodes a protein that is highly similar to the CDC10 protein of Saccharomyces cerevisiae. The protein also shares similarity with Diff 6 of Drosophila and with H5 of mouse. Each of these similar proteins, including the yeast CDC10, contains a GTP-binding motif. The yeast CDC10 protein is a structural component of the 10 nm filament which lies inside the cytoplasmic membrane and is essential for cytokinesis. This human protein functions in gliomagenesis and in the suppression of glioma cell growth, and it is required for the association of centromere-associated protein E with the kinetochore. Alternative splicing results in multiple transcript variants. Several related pseudogenes have been identified on chromosomes 5, 7, 9, 10, 11, 14, 17 and 19. [provided by RefSeq, Jul 2011] (NCBI Entrez Gene Database, 989)
External Link http://www.broadinstitute.org/gsea/msigdb/cards/MORF_CDC10
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Genes

143 co-expressed genes for SEPT7 from the MSigDB Cancer Gene Co-expression Modules dataset.

Symbol Name
AATF apoptosis antagonizing transcription factor
ACAP2 ArfGAP with coiled-coil, ankyrin repeat and PH domains 2
ADD1 adducin 1 (alpha)
AFF1 AF4/FMR2 family, member 1
AFG3L2 AFG3-like AAA ATPase 2
ANAPC5 anaphase promoting complex subunit 5
AP3D1 adaptor-related protein complex 3, delta 1 subunit
ARHGEF7 Rho guanine nucleotide exchange factor (GEF) 7
ARIH2 ariadne RBR E3 ubiquitin protein ligase 2
ARL2BP ADP-ribosylation factor-like 2 binding protein
ARPC3 actin related protein 2/3 complex, subunit 3, 21kDa
ASH2L ash2 (absent, small, or homeotic)-like (Drosophila)
ATP11B ATPase, class VI, type 11B
ATXN2L ataxin 2-like
BMS1 BMS1 ribosome biogenesis factor
BRD8 bromodomain containing 8
CALM2 calmodulin 2 (phosphorylase kinase, delta)
CAPRIN1 cell cycle associated protein 1
CAPZA1 capping protein (actin filament) muscle Z-line, alpha 1
CASC3 cancer susceptibility candidate 3
CCT4 chaperonin containing TCP1, subunit 4 (delta)
CDK11A cyclin-dependent kinase 11A
CDK2 cyclin-dependent kinase 2
CHUK conserved helix-loop-helix ubiquitous kinase
CLSTN1 calsyntenin 1
CNOT1 CCR4-NOT transcription complex, subunit 1
CNP 2',3'-cyclic nucleotide 3' phosphodiesterase
COPS2 COP9 signalosome subunit 2
CRKL v-crk avian sarcoma virus CT10 oncogene homolog-like
CS citrate synthase
CTDNEP1 CTD nuclear envelope phosphatase 1
CUL2 cullin 2
DDB1 damage-specific DNA binding protein 1, 127kDa
DDX46 DEAD (Asp-Glu-Ala-Asp) box polypeptide 46
DEK DEK proto-oncogene
DHX38 DEAH (Asp-Glu-Ala-His) box polypeptide 38
DIAPH1 diaphanous-related formin 1
DNAJC8 DnaJ (Hsp40) homolog, subfamily C, member 8
DSCR3 Down syndrome critical region 3
DUT deoxyuridine triphosphatase
DYRK2 dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 2
EIF1AX eukaryotic translation initiation factor 1A, X-linked
EIF3M eukaryotic translation initiation factor 3, subunit M
EIF4A2 eukaryotic translation initiation factor 4A2
FOXJ3 forkhead box J3
FRG1 FSHD region gene 1
GAK cyclin G associated kinase
GNB1 guanine nucleotide binding protein (G protein), beta polypeptide 1
GTF2A2 general transcription factor IIA, 2, 12kDa
HMGB1 high mobility group box 1
HNRNPA2B1 heterogeneous nuclear ribonucleoprotein A2/B1
HNRNPD heterogeneous nuclear ribonucleoprotein D (AU-rich element RNA binding protein 1, 37kDa)
HNRNPH2 heterogeneous nuclear ribonucleoprotein H2 (H')
HNRNPH3 heterogeneous nuclear ribonucleoprotein H3 (2H9)
HNRNPK heterogeneous nuclear ribonucleoprotein K
HNRNPL heterogeneous nuclear ribonucleoprotein L
HNRNPR heterogeneous nuclear ribonucleoprotein R
HSPA8 heat shock 70kDa protein 8
ILF2 interleukin enhancer binding factor 2
IMMT inner membrane protein, mitochondrial
KDM3B lysine (K)-specific demethylase 3B
KHDRBS1 KH domain containing, RNA binding, signal transduction associated 1
KRAS Kirsten rat sarcoma viral oncogene homolog
LANCL1 LanC lantibiotic synthetase component C-like 1 (bacterial)
LBR lamin B receptor
LRPPRC leucine-rich pentatricopeptide repeat containing
MCFD2 multiple coagulation factor deficiency 2
MORC3 MORC family CW-type zinc finger 3
NACA nascent polypeptide-associated complex alpha subunit
NAE1 NEDD8 activating enzyme E1 subunit 1
NAP1L4 nucleosome assembly protein 1-like 4
NONO non-POU domain containing, octamer-binding
NSA2 NSA2 ribosome biogenesis homolog (S. cerevisiae)
NUP188 nucleoporin 188kDa
OXA1L oxidase (cytochrome c) assembly 1-like
PGK1 phosphoglycerate kinase 1
PHIP pleckstrin homology domain interacting protein
PIN1 peptidylprolyl cis/trans isomerase, NIMA-interacting 1
PITPNM1 phosphatidylinositol transfer protein, membrane-associated 1
PLIN3 perilipin 3
POLR2A polymerase (RNA) II (DNA directed) polypeptide A, 220kDa
POLR2C polymerase (RNA) II (DNA directed) polypeptide C, 33kDa
POM121 POM121 transmembrane nucleoporin
PPP2CA protein phosphatase 2, catalytic subunit, alpha isozyme
PRKAG1 protein kinase, AMP-activated, gamma 1 non-catalytic subunit
PRKDC protein kinase, DNA-activated, catalytic polypeptide
PRKRA protein kinase, interferon-inducible double stranded RNA dependent activator
PRPF8 pre-mRNA processing factor 8
PSMA1 proteasome (prosome, macropain) subunit, alpha type, 1
PSME4 proteasome (prosome, macropain) activator subunit 4
PTP4A2 protein tyrosine phosphatase type IVA, member 2
PUM2 pumilio RNA-binding family member 2
RBM6 RNA binding motif protein 6
RFC1 replication factor C (activator 1) 1, 145kDa
RNF44 ring finger protein 44
RNGTT RNA guanylyltransferase and 5'-phosphatase
RNPS1 RNA binding protein S1, serine-rich domain
RPA2 replication protein A2, 32kDa
RPL22 ribosomal protein L22
SAFB scaffold attachment factor B
SEC63 SEC63 homolog (S. cerevisiae)
SEPT7 septin 7
SERP1 stress-associated endoplasmic reticulum protein 1
SFSWAP splicing factor, suppressor of white-apricot family
SHOC2 soc-2 suppressor of clear homolog (C. elegans)
SMC5 structural maintenance of chromosomes 5
SMNDC1 survival motor neuron domain containing 1
SNRNP200 small nuclear ribonucleoprotein 200kDa (U5)
SPG11 spastic paraplegia 11 (autosomal recessive)
SRRM1 serine/arginine repetitive matrix 1
SRSF11 serine/arginine-rich splicing factor 11
SSB Sjogren syndrome antigen B (autoantigen La)
STARD7 StAR-related lipid transfer (START) domain containing 7
STK24 serine/threonine kinase 24
SUGP2 SURP and G patch domain containing 2
SUMO2 small ubiquitin-like modifier 2
SUMO4 small ubiquitin-like modifier 4
SUN2 Sad1 and UNC84 domain containing 2
TACC1 transforming, acidic coiled-coil containing protein 1
TAX1BP1 Tax1 (human T-cell leukemia virus type I) binding protein 1
TCEA1 transcription elongation factor A (SII), 1
TCOF1 Treacher Collins-Franceschetti syndrome 1
TERF1 telomeric repeat binding factor (NIMA-interacting) 1
TERF2IP telomeric repeat binding factor 2, interacting protein
TFAP4 transcription factor AP-4 (activating enhancer binding protein 4)
TIAL1 TIA1 cytotoxic granule-associated RNA binding protein-like 1
TIMM17A translocase of inner mitochondrial membrane 17 homolog A (yeast)
TMEM123 transmembrane protein 123
TP53BP1 tumor protein p53 binding protein 1
TRRAP transformation/transcription domain-associated protein
TUBA3C tubulin, alpha 3c
TXLNA taxilin alpha
USP1 ubiquitin specific peptidase 1
VAMP3 vesicle-associated membrane protein 3
VDAC3 voltage-dependent anion channel 3
XPO1 exportin 1
XPO6 exportin 6
XPO7 exportin 7
XRCC5 X-ray repair complementing defective repair in Chinese hamster cells 5 (double-strand-break rejoining)
YWHAQ tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, theta
ZC3H15 zinc finger CCCH-type containing 15
ZNF131 zinc finger protein 131
ZPR1 ZPR1 zinc finger