SESTD1 Gene Set

Dataset CM4AI KOLF21J CRISPRi Gene Perturbation Atlas
Category transcriptomics
Type gene perturbation
Description SEC14 and spectrin domains 1| (NCBI Entrez Gene Database, 91404)
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Genes

345 genes differentially expressed following the SESTD1 gene perturbation from the CM4AI KOLF21J CRISPRi Gene Perturbation Atlas.

increased expression

Symbol Name Standardized Value
SLC6A18 solute carrier family 6 (neutral amino acid transporter), member 18 2.80054
CABS1 calcium-binding protein, spermatid-specific 1 2.80054
CCL5 chemokine (C-C motif) ligand 5 2.80054
LRRC52 leucine rich repeat containing 52 2.80054
LRG1 leucine-rich alpha-2-glycoprotein 1 2.80054
GPR26 G protein-coupled receptor 26 2.80054
TNIP3 TNFAIP3 interacting protein 3 2.80054
PECAM1 platelet/endothelial cell adhesion molecule 1 2.80054
BIRC3 baculoviral IAP repeat containing 3 2.80054
CXCL1 chemokine (C-X-C motif) ligand 1 (melanoma growth stimulating activity, alpha) 2.80054
APLN apelin 2.80054
CLEC19A C-type lectin domain family 19, member A 2.80054
SOX14 SRY (sex determining region Y)-box 14 2.80054
ENPP6 ectonucleotide pyrophosphatase/phosphodiesterase 6 2.80054
COL20A1 collagen, type XX, alpha 1 2.80054
CEMP1 cementum protein 1 2.80054
SLC6A1 solute carrier family 6 (neurotransmitter transporter), member 1 2.80054
CARD16 caspase recruitment domain family, member 16 2.80054
NPAP1 nuclear pore associated protein 1 2.80054
SDR9C7 short chain dehydrogenase/reductase family 9C, member 7 2.80054
CD14 CD14 molecule 2.80054
ZEB2 zinc finger E-box binding homeobox 2 2.80054
TRPV3 transient receptor potential cation channel, subfamily V, member 3 2.80054
ADAMTSL5 ADAMTS-like 5 2.80054
TDRD9 tudor domain containing 9 2.80054
BTBD16 BTB (POZ) domain containing 16 2.80054
HRG histidine-rich glycoprotein 2.80054
OR51A4 olfactory receptor, family 51, subfamily A, member 4 2.80054
RBP4 retinol binding protein 4, plasma 2.80054
TSSK1B testis-specific serine kinase 1B 2.80054
OR6B1 olfactory receptor, family 6, subfamily B, member 1 2.80054
ZC3H11B zinc finger CCCH-type containing 11B pseudogene 2.80054
CORIN corin, serine peptidase 2.80054
NRGN neurogranin (protein kinase C substrate, RC3) 2.80054
CCDC83 coiled-coil domain containing 83 2.80054
FGF7 fibroblast growth factor 7 2.80054
EMCN endomucin 2.80054
SPP2 secreted phosphoprotein 2, 24kDa 2.80054
HBB hemoglobin, beta 2.80054
TREML1 triggering receptor expressed on myeloid cells-like 1 2.80054
OXT oxytocin/neurophysin I prepropeptide 2.80054
RXRG retinoid X receptor, gamma 2.80054
HIC1 hypermethylated in cancer 1 2.80054
EVPL envoplakin 2.80054
CYP4A22 cytochrome P450, family 4, subfamily A, polypeptide 22 2.80054
ARSH arylsulfatase family, member H 2.80054
NLRP9 NLR family, pyrin domain containing 9 2.80054
ERLN endoregulin 2.80054
TMIGD1 transmembrane and immunoglobulin domain containing 1 2.80054
SPRR2A small proline-rich protein 2A 2.80054
FMO2 flavin containing monooxygenase 2 (non-functional) 2.80054
PKD2L1 polycystic kidney disease 2-like 1 2.80054
IFIT1B interferon-induced protein with tetratricopeptide repeats 1B 2.80054
HNRNPCL2 heterogeneous nuclear ribonucleoprotein C-like 2 2.80054
GDF9 growth differentiation factor 9 2.80054
GPR85 G protein-coupled receptor 85 2.80054
IL1R2 interleukin 1 receptor, type II 2.80054
TAS2R60 taste receptor, type 2, member 60 2.80054
ST6GALNAC2 ST6 (alpha-N-acetyl-neuraminyl-2,3-beta-galactosyl-1,3)-N-acetylgalactosaminide alpha-2,6-sialyltransferase 2 2.80054
ZNF728 zinc finger protein 728 2.80054
LITAFD LITAF domain containing 2.80054
STRIT1 small transmembrane regulator of ion transport 1 2.80054
CFAP97D2 CFAP97 domain containing 2 2.80054
OR52P1 olfactory receptor family 52 subfamily P member 1 (gene/pseudogene) 2.80054
TRARG1 trafficking regulator of GLUT4 (SLC2A4) 1 2.80054
CCDC198 coiled-coil domain containing 198 2.80054
CFAP65 cilia and flagella associated protein 65 2.80054
STING1 stimulator of interferon response cGAMP interactor 1 2.80054
SLC7A13 solute carrier family 7 (anionic amino acid transporter), member 13 2.80054
C6 complement component 6 2.80054
C1QTNF9 C1q and tumor necrosis factor related protein 9 2.80054
APOBEC4 apolipoprotein B mRNA editing enzyme, catalytic polypeptide-like 4 (putative) 2.80054
ARL14EPL ADP-ribosylation factor-like 14 effector protein-like 2.80054
PCDHA2 protocadherin alpha 2 2.80054
ATP13A5 ATPase type 13A5 2.80054
PRKAG3 protein kinase, AMP-activated, gamma 3 non-catalytic subunit 2.80054
TBX21 T-box 21 2.80054
SLC22A11 solute carrier family 22 (organic anion/urate transporter), member 11 2.80054
SLC22A14 solute carrier family 22, member 14 2.80054
FRG2 FSHD region gene 2 2.80054
HRH1 histamine receptor H1 2.80054
PTPRC protein tyrosine phosphatase, receptor type, C 2.80054
NXPE2 neurexophilin and PC-esterase domain family, member 2 2.80054
TNFRSF17 tumor necrosis factor receptor superfamily, member 17 2.80054
RUNX3 runt-related transcription factor 3 2.80054
MIP major intrinsic protein of lens fiber 2.80054
C1ORF162 chromosome 1 open reading frame 162 2.80054
SCRT2 scratch family zinc finger 2 2.80054
NPIPB9 nuclear pore complex interacting protein family, member B9 2.80054
CYP3A4 cytochrome P450, family 3, subfamily A, polypeptide 4 2.80054
OR51B2 olfactory receptor, family 51, subfamily B, member 2 (gene/pseudogene) 2.80054
FAM78A family with sequence similarity 78, member A 2.80054
CCR6 chemokine (C-C motif) receptor 6 2.80054
RNF17 ring finger protein 17 2.80054
SMIM22 small integral membrane protein 22 2.80054
GRK1 G protein-coupled receptor kinase 1 2.80054
AQP8 aquaporin 8 2.80054
HHATL hedgehog acyltransferase-like 2.80054
EMX2 empty spiracles homeobox 2 2.80054
BPIFB1 BPI fold containing family B, member 1 2.80054
CALHM1 calcium homeostasis modulator 1 2.80054
TMEM202 transmembrane protein 202 2.80054
TPSB2 tryptase beta 2 (gene/pseudogene) 2.80054
SPATA3 spermatogenesis associated 3 2.80054
FATE1 fetal and adult testis expressed 1 2.80054
C18ORF63 chromosome 18 open reading frame 63 2.80054
PMP2 peripheral myelin protein 2 2.80054
SLC52A1 solute carrier family 52 (riboflavin transporter), member 1 2.80054
KRT9 keratin 9, type I 2.80054
GFI1B growth factor independent 1B transcription repressor 2.80054
TMEM132D transmembrane protein 132D 2.80054
MRLN myoregulin 2.80054
NOG noggin 2.80054
ZNF703 zinc finger protein 703 2.80054
OXGR1 oxoglutarate (alpha-ketoglutarate) receptor 1 2.80054
MAB21L3 mab-21-like 3 (C. elegans) 2.80054
POU2AF1 POU class 2 associating factor 1 2.80054
CCDC25 coiled-coil domain containing 25 2.80054
IDI2 isopentenyl-diphosphate delta isomerase 2 2.80054
RGS4 regulator of G-protein signaling 4 2.80054
SEL1L2 sel-1 suppressor of lin-12-like 2 (C. elegans) 2.80054
SH2D1A SH2 domain containing 1A 2.80054
MYADML2 myeloid-associated differentiation marker-like 2 2.80054
SPTA1 spectrin, alpha, erythrocytic 1 2.80054
OPTC opticin 2.80054
OTP orthopedia homeobox 2.80054
C10ORF105 chromosome 10 open reading frame 105 2.80054
SYNGR4 synaptogyrin 4 2.80054
B4GALNT1 beta-1,4-N-acetyl-galactosaminyl transferase 1 2.80054
DSC1 desmocollin 1 2.80054
IL1B interleukin 1, beta 2.80054
SEC14L3 SEC14-like 3 (S. cerevisiae) 2.80054
TEX19 testis expressed 19 2.80054
KISS1 KiSS-1 metastasis-suppressor 2.80054
THBD thrombomodulin 2.80054
KLK11 kallikrein-related peptidase 11 2.80054
SVOP SV2 related protein homolog (rat) 2.80054
PDCD1LG2 programmed cell death 1 ligand 2 2.80054
CFB complement factor B 2.80054
EPX eosinophil peroxidase 2.80054
CIDEA cell death-inducing DFFA-like effector a 2.80054
TRPM8 transient receptor potential cation channel, subfamily M, member 8 2.80054
GPRC5D G protein-coupled receptor, class C, group 5, member D 2.80054
KCNK16 potassium channel, two pore domain subfamily K, member 16 2.80054
CIB4 calcium and integrin binding family member 4 2.80054
ANGPTL5 angiopoietin-like 5 2.80054
OR13A1 olfactory receptor, family 13, subfamily A, member 1 2.80054
TGM1 transglutaminase 1 2.80054
AMER3 APC membrane recruitment protein 3 2.80054
ACKR2 atypical chemokine receptor 2 2.80054
NUTM2F NUT family member 2F 2.80054
NUTM2B NUT family member 2B 2.80054
CCNB3 cyclin B3 2.80054
NTSR2 neurotensin receptor 2 2.80054
AQP1 aquaporin 1 (Colton blood group) 2.80054
CYP2W1 cytochrome P450, family 2, subfamily W, polypeptide 1 2.80054
NBPF9 neuroblastoma breakpoint family, member 9 2.80054
KCNC2 potassium channel, voltage gated Shaw related subfamily C, member 2 2.80054
OR14A2 olfactory receptor, family 14, subfamily A, member 2 2.80054
PLA2G4E phospholipase A2, group IVE 2.80054
HEMGN hemogen 2.80054
CMTM5 CKLF-like MARVEL transmembrane domain containing 5 2.80054
PLEKHS1 pleckstrin homology domain containing, family S member 1 2.80054
SHISA3 shisa family member 3 2.80054
CHRDL2 chordin-like 2 2.80054
AOX1 aldehyde oxidase 1 2.78924
LTV1 LTV1 ribosome biogenesis factor 2.78457
ZNF709 zinc finger protein 709 2.75249
SFXN5 sideroflexin 5 2.68555
SAPCD1 suppressor APC domain containing 1 2.68555
ZNF827 zinc finger protein 827 2.62499
ARK2C arkadia (RNF111) C-terminal like ring finger ubiquitin ligase 2C 2.62499
NUTF2 nuclear transport factor 2 2.5579
SPTB spectrin, beta, erythrocytic 2.53711
DIP2C DIP2 disco-interacting protein 2 homolog C (Drosophila) 2.42329
SCLY selenocysteine lyase 2.42329
RFTN2 raftlin family member 2 2.42267
HTRA3 HtrA serine peptidase 3 2.38813
TRIP4 thyroid hormone receptor interactor 4 2.38412
TSNAX translin-associated factor X 2.3841
FYTTD1 forty-two-three domain containing 1 2.37886
SLITRK4 SLIT and NTRK-like family, member 4 2.3747
C1ORF52 chromosome 1 open reading frame 52 2.3574
STK17B serine/threonine kinase 17b 2.30961
ERCC6L excision repair cross-complementation group 6-like 2.30493
AMER2 APC membrane recruitment protein 2 2.30426
MISP3 MISP family member 3 2.30354
MARS2 methionyl-tRNA synthetase 2, mitochondrial 2.29148
PBXIP1 pre-B-cell leukemia homeobox interacting protein 1 2.24777
RBM15 RNA binding motif protein 15 2.2464
DIS3L2 DIS3 like 3'-5' exoribonuclease 2 2.24461
SPATA17 spermatogenesis associated 17 2.24165
ZNF664 zinc finger protein 664 2.2324
ADGRE2 adhesion G protein-coupled receptor E2 2.22558
MIPOL1 mirror-image polydactyly 1 2.22295
NGDN neuroguidin, EIF4E binding protein 2.22132
CORO6 coronin 6 2.21306
ZNF582 zinc finger protein 582 2.20679
RNF207 ring finger protein 207 2.20679
GLA galactosidase, alpha 2.19401
ZNF519 zinc finger protein 519 2.18776
MAP3K11 mitogen-activated protein kinase kinase kinase 11 2.15419
LRRC8C leucine rich repeat containing 8 family, member C 2.14743
TMEM216 transmembrane protein 216 2.13932
HSD17B11 hydroxysteroid (17-beta) dehydrogenase 11 2.12396
SH3KBP1 SH3-domain kinase binding protein 1 2.12396
BDP1 B double prime 1, subunit of RNA polymerase III transcription initiation factor IIIB 2.12396
AFG2A AFG2 AAA ATPase homolog A 2.12205
ABR active BCR-related 2.11713
CCDC127 coiled-coil domain containing 127 2.10018
ADGRV1 adhesion G protein-coupled receptor V1 2.0808
MUTYH mutY homolog 2.05194
TM2D1 TM2 domain containing 1 2.05194
CERS1 ceramide synthase 1 2.04817
PSME3IP1 proteasome activator subunit 3 interacting protein 1 2.03698
PLA2G4C phospholipase A2, group IVC (cytosolic, calcium-independent) 2.03424
DAPK3 death-associated protein kinase 3 2.02853
IGHMBP2 immunoglobulin mu binding protein 2 2.02793
MGRN1 mahogunin ring finger 1, E3 ubiquitin protein ligase 2.01871
HOMER2 homer scaffolding protein 2 2.01469
SLC16A5 solute carrier family 16 (monocarboxylate transporter), member 5 2.01443
LOC728743 zinc finger protein pseudogene 2.00904
TP53INP2 tumor protein p53 inducible nuclear protein 2 2.00329

decreased expression

Symbol Name Standardized Value
BRINP2 bone morphogenetic protein/retinoic acid inducible neural-specific 2 -2.80054
TGM2 transglutaminase 2 -2.80054
NTRK1 neurotrophic tyrosine kinase, receptor, type 1 -2.80054
COX7A1 cytochrome c oxidase subunit VIIa polypeptide 1 (muscle) -2.80054
SIM2 single-minded family bHLH transcription factor 2 -2.80054
PTGDR prostaglandin D2 receptor (DP) -2.80054
SAMD15 sterile alpha motif domain containing 15 -2.80054
SHC4 SHC (Src homology 2 domain containing) family, member 4 -2.80054
GP1BA glycoprotein Ib (platelet), alpha polypeptide -2.80054
PCDHGC3 protocadherin gamma subfamily C, 3 -2.80054
MROH5 maestro heat-like repeat family member 5 -2.80054
IGFBP7 insulin-like growth factor binding protein 7 -2.80054
ANXA1 annexin A1 -2.80054
HMGCLL1 3-hydroxymethyl-3-methylglutaryl-CoA lyase-like 1 -2.80054
MOGAT3 monoacylglycerol O-acyltransferase 3 -2.80054
MUC20 mucin 20, cell surface associated -2.80054
MMP20 matrix metallopeptidase 20 -2.80054
GALR2 galanin receptor 2 -2.80054
KCNJ8 potassium channel, inwardly rectifying subfamily J, member 8 -2.80054
SLC22A6 solute carrier family 22 (organic anion transporter), member 6 -2.80054
ZNF804B zinc finger protein 804B -2.80054
UCP3 uncoupling protein 3 (mitochondrial, proton carrier) -2.80054
TOMM20L translocase of outer mitochondrial membrane 20 homolog (yeast)-like -2.80054
SESTD1 SEC14 and spectrin domains 1 -2.80054
CYP2A13 cytochrome P450, family 2, subfamily A, polypeptide 13 -2.80054
SV2B synaptic vesicle glycoprotein 2B -2.80054
JAKMIP1 janus kinase and microtubule interacting protein 1 -2.80054
XIRP2 xin actin binding repeat containing 2 -2.80054
VXN vexin -2.80054
HTR1B 5-hydroxytryptamine (serotonin) receptor 1B, G protein-coupled -2.80054
NIBAN3 niban apoptosis regulator 3 -2.80054
TF transferrin -2.80054
NMBR neuromedin B receptor -2.80054
UBE2L5 ubiquitin conjugating enzyme E2 L5 -2.80054
CNR1 cannabinoid receptor 1 (brain) -2.80054
MYOCOS myocilin opposite strand -2.80054
PPP3CB protein phosphatase 3, catalytic subunit, beta isozyme -2.80054
GIPR gastric inhibitory polypeptide receptor -2.80054
SERTM2 serine rich and transmembrane domain containing 2 -2.80054
PNMA8C PNMA family member 8C -2.80054
ACKR5 atypical chemokine receptor 5 -2.80054
PROC protein C (inactivator of coagulation factors Va and VIIIa) -2.80054
GTF2F1 general transcription factor IIF, polypeptide 1, 74kDa -2.80054
PCDH11X protocadherin 11 X-linked -2.73352
ZNF616 zinc finger protein 616 -2.72096
ANPEP alanyl (membrane) aminopeptidase -2.64568
NPHP3 nephronophthisis 3 (adolescent) -2.64568
CD53 CD53 molecule -2.64568
PCDHA11 protocadherin alpha 11 -2.64568
APH1A APH1A gamma secretase subunit -2.64319
MUS81 MUS81 structure-specific endonuclease subunit -2.57911
RFX4 regulatory factor X, 4 (influences HLA class II expression) -2.57881
PRMT3 protein arginine methyltransferase 3 -2.56765
STX18 syntaxin 18 -2.55453
ASPG asparaginase -2.50623
C8ORF33 chromosome 8 open reading frame 33 -2.50623
HERPUD2 HERPUD family member 2 -2.4699
DPYD dihydropyrimidine dehydrogenase -2.45169
PFKL phosphofructokinase, liver -2.43403
PRDM5 PR domain containing 5 -2.40075
RPL22 ribosomal protein L22 -2.39339
DUSP4 dual specificity phosphatase 4 -2.37886
GLIS3 GLIS family zinc finger 3 -2.35018
LRRC40 leucine rich repeat containing 40 -2.33978
IGF2R insulin-like growth factor 2 receptor -2.32993
KLHL14 kelch-like family member 14 -2.31238
ATPSCKMT ATP synthase c subunit lysine N-methyltransferase -2.30961
ROCK2 Rho-associated, coiled-coil containing protein kinase 2 -2.30932
INO80C INO80 complex subunit C -2.30737
SPART spartin -2.30493
LMTK3 lemur tyrosine kinase 3 -2.28704
PRMT1 protein arginine methyltransferase 1 -2.28171
TMEM268 transmembrane protein 268 -2.27693
ZNF517 zinc finger protein 517 -2.26642
CRYGS crystallin, gamma S -2.26642
CCDC174 coiled-coil domain containing 174 -2.26642
SRP72 signal recognition particle 72kDa -2.26642
CDK5RAP2 CDK5 regulatory subunit associated protein 2 -2.26229
APPBP2 amyloid beta precursor protein (cytoplasmic tail) binding protein 2 -2.25466
PDP1 pyruvate dehyrogenase phosphatase catalytic subunit 1 -2.25294
MCUB mitochondrial calcium uniporter dominant negative subunit beta -2.25294
PABIR3 PABIR family member 3 -2.25095
MCAM melanoma cell adhesion molecule -2.24777
ZNF93 zinc finger protein 93 -2.24121
TARS1 threonyl-tRNA synthetase 1 -2.22753
TCF24 transcription factor 24 -2.22132
N4BP1 NEDD4 binding protein 1 -2.2173
KCTD9 potassium channel tetramerization domain containing 9 -2.20624
ALDH1A2 aldehyde dehydrogenase 1 family, member A2 -2.20597
ZNF365 zinc finger protein 365 -2.20597
MARCHF6 membrane associated ring-CH-type finger 6 -2.17897
TBC1D32 TBC1 domain family, member 32 -2.17289
WDR19 WD repeat domain 19 -2.17234
DNAAF9 dynein axonemal assembly factor 9 -2.16894
CAV1 caveolin 1, caveolae protein, 22kDa -2.14886
PPP3CA protein phosphatase 3, catalytic subunit, alpha isozyme -2.14743
DNAJC28 DnaJ (Hsp40) homolog, subfamily C, member 28 -2.14193
RPSA ribosomal protein SA -2.14141
SAMTOR S-adenosylmethionine sensor upstream of mTORC1 -2.14041
ZC3H12B zinc finger CCCH-type containing 12B -2.14006
GRAMD1B GRAM domain containing 1B -2.12946
GARRE1 granule associated Rac and RHOG effector 1 -2.12396
FDFT1 farnesyl-diphosphate farnesyltransferase 1 -2.12396
GPI glucose-6-phosphate isomerase -2.12108
PPAN peter pan homolog (Drosophila) -2.11071
SLC17A5 solute carrier family 17 (acidic sugar transporter), member 5 -2.0816
PNRC1 proline-rich nuclear receptor coactivator 1 -2.07821
UQCRB ubiquinol-cytochrome c reductase binding protein -2.07698
LDAH lipid droplet associated hydrolase -2.07265
VPS41 vacuolar protein sorting 41 homolog (S. cerevisiae) -2.06296
PELI3 pellino E3 ubiquitin protein ligase family member 3 -2.06296
H3-3B H3.3 histone B -2.05877
XDH xanthine dehydrogenase -2.05837
CFLAR CASP8 and FADD-like apoptosis regulator -2.05602
CASP8AP2 caspase 8 associated protein 2 -2.05573
SMTN smoothelin -2.04479
SLC5A2 solute carrier family 5 (sodium/glucose cotransporter), member 2 -2.03457
PXN paxillin -2.02375
BRWD3 bromodomain and WD repeat domain containing 3 -2.00904
SLC16A6 solute carrier family 16, member 6 -2.00218
ABCA12 ATP-binding cassette, sub-family A (ABC1), member 12 -2.00218
IFI6 interferon, alpha-inducible protein 6 -2.00218