SETD3 Gene Set

Dataset CM4AI KOLF21J CRISPRi Gene Perturbation Atlas
Category transcriptomics
Type gene perturbation
Description SET domain containing 3| (NCBI Entrez Gene Database, 84193)
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Genes

313 genes differentially expressed following the SETD3 gene perturbation from the CM4AI KOLF21J CRISPRi Gene Perturbation Atlas.

increased expression

Symbol Name Standardized Value
TMPRSS11F transmembrane protease, serine 11F 2.75208
PLIN1 perilipin 1 2.75208
TMEM176A transmembrane protein 176A 2.75208
TEX13A testis expressed 13A 2.75208
TEX13B testis expressed 13B 2.75208
PON1 paraoxonase 1 2.75208
PCDHB4 protocadherin beta 4 2.75208
NCF1 neutrophil cytosolic factor 1 2.75208
CYP4A11 cytochrome P450, family 4, subfamily A, polypeptide 11 2.75208
GJB1 gap junction protein, beta 1, 32kDa 2.75208
KCNJ9 potassium channel, inwardly rectifying subfamily J, member 9 2.75208
ALOX15 arachidonate 15-lipoxygenase 2.75208
CTRC chymotrypsin C (caldecrin) 2.75208
FAM187B family with sequence similarity 187, member B 2.75208
COL20A1 collagen, type XX, alpha 1 2.75208
SLC6A4 solute carrier family 6 (neurotransmitter transporter), member 4 2.75208
ZNF503 zinc finger protein 503 2.75208
CDH5 cadherin 5, type 2 (vascular endothelium) 2.75208
CHRND cholinergic receptor, nicotinic, delta (muscle) 2.75208
WDR87 WD repeat domain 87 2.75208
GPR52 G protein-coupled receptor 52 2.75208
TRH thyrotropin-releasing hormone 2.75208
ROBO4 roundabout, axon guidance receptor, homolog 4 (Drosophila) 2.75208
LYVE1 lymphatic vessel endothelial hyaluronan receptor 1 2.75208
FAM90A1 family with sequence similarity 90, member A1 2.75208
SETSIP SET-like protein 2.75208
PTGS1 prostaglandin-endoperoxide synthase 1 (prostaglandin G/H synthase and cyclooxygenase) 2.75208
NMUR2 neuromedin U receptor 2 2.75208
GPAT2 glycerol-3-phosphate acyltransferase 2, mitochondrial 2.75208
TDO2 tryptophan 2,3-dioxygenase 2.75208
SLC10A6 solute carrier family 10 (sodium/bile acid cotransporter), member 6 2.75208
LEP leptin 2.75208
RNASE1 ribonuclease, RNase A family, 1 (pancreatic) 2.75208
METTL21C methyltransferase like 21C 2.75208
DHRS9 dehydrogenase/reductase (SDR family) member 9 2.75208
CCDC38 coiled-coil domain containing 38 2.75208
MAGED4 melanoma antigen family D4 2.75208
CSMD3 CUB and Sushi multiple domains 3 2.75208
FAM156B family with sequence similarity 156, member B 2.75208
GDNF glial cell derived neurotrophic factor 2.75208
SSTR5 somatostatin receptor 5 2.75208
SSTR3 somatostatin receptor 3 2.75208
PBOV1 prostate and breast cancer overexpressed 1 2.75208
ARSF arylsulfatase F 2.75208
TRPV6 transient receptor potential cation channel, subfamily V, member 6 2.75208
GNAT1 guanine nucleotide binding protein (G protein), alpha transducing activity polypeptide 1 2.75208
MS4A15 membrane-spanning 4-domains, subfamily A, member 15 2.75208
SOST sclerostin 2.75208
NTRK1 neurotrophic tyrosine kinase, receptor, type 1 2.75208
LOC122526780 uncharacterized LOC122526780 2.75208
IRAG2 inositol 1,4,5-triphosphate receptor associated 2 2.75208
NFIX nuclear factor I/X (CCAAT-binding transcription factor) 2.75208
ERVW-1 endogenous retrovirus group W, member 1 2.75208
CES4A carboxylesterase 4A 2.75208
GIPC3 GIPC PDZ domain containing family, member 3 2.75208
TMOD4 tropomodulin 4 (muscle) 2.75208
HAO2 hydroxyacid oxidase 2 (long chain) 2.75208
DNAAF1 dynein, axonemal, assembly factor 1 2.75208
SLC2A5 solute carrier family 2 (facilitated glucose/fructose transporter), member 5 2.75208
TMPRSS4 transmembrane protease, serine 4 2.75208
SLC66A2 solute carrier family 66 member 2 2.75208
CCN5 cellular communication network factor 5 2.75208
TMA7B translation machinery associated 7 homolog B 2.75208
SMIM45 small integral membrane protein 45 2.75208
CTXND1 cortexin domain containing 1 2.75208
SPAAR small regulatory polypeptide of amino acid response 2.75208
SMIM35 small integral membrane protein 35 2.75208
DNAAF6 dynein axonemal assembly factor 6 2.75208
NFILZ NFIL3 like basic leucine zipper 2.75208
CFAP97D1 CFAP97 domain containing 1 2.75208
VXN vexin 2.75208
ANKRD40CL ANKRD40 C-terminal like 2.75208
IQCF1 IQ motif containing F1 2.75208
DOK2 docking protein 2, 56kDa 2.75208
TLR6 toll-like receptor 6 2.75208
LRIT3 leucine-rich repeat, immunoglobulin-like and transmembrane domains 3 2.75208
NPIPB9 nuclear pore complex interacting protein family, member B9 2.75208
TMCO2 transmembrane and coiled-coil domains 2 2.75208
CCNG1 cyclin G1 2.75208
PCDHB10 protocadherin beta 10 2.75208
PCDHA3 protocadherin alpha 3 2.75208
FOXD1 forkhead box D1 2.75208
HHEX hematopoietically expressed homeobox 2.75208
CYP26C1 cytochrome P450, family 26, subfamily C, polypeptide 1 2.75208
AWAT2 acyl-CoA wax alcohol acyltransferase 2 2.75208
UBL4B ubiquitin-like 4B 2.75208
C15ORF62 chromosome 15 open reading frame 62 2.75208
HTR3C 5-hydroxytryptamine (serotonin) receptor 3C, ionotropic 2.75208
SDR16C5 short chain dehydrogenase/reductase family 16C, member 5 2.75208
PRG4 proteoglycan 4 2.75208
COX8C cytochrome c oxidase subunit VIIIC 2.75208
LRRC72 leucine rich repeat containing 72 2.75208
FRK fyn-related Src family tyrosine kinase 2.75208
NR0B1 nuclear receptor subfamily 0, group B, member 1 2.75208
PIWIL1 piwi-like RNA-mediated gene silencing 1 2.75208
C1QL2 complement component 1, q subcomponent-like 2 2.75208
HBA2 hemoglobin, alpha 2 2.75208
CGB2 chorionic gonadotropin, beta polypeptide 2 2.75208
IGFBP7 insulin-like growth factor binding protein 7 2.75208
OCM oncomodulin 2.75208
GAL3ST2 galactose-3-O-sulfotransferase 2 2.75208
IL17REL interleukin 17 receptor E-like 2.75208
A3GALT2 alpha 1,3-galactosyltransferase 2 2.75208
PCDHGB1 protocadherin gamma subfamily B, 1 2.75208
NBPF8 neuroblastoma breakpoint family, member 8 2.75208
TMEM150B transmembrane protein 150B 2.75208
MXRA5 matrix-remodelling associated 5 2.75208
IL12A interleukin 12A 2.75208
BPIFA3 BPI fold containing family A, member 3 2.75208
SLC17A8 solute carrier family 17 (vesicular glutamate transporter), member 8 2.75208
SMIM15 small integral membrane protein 15 2.75208
FZD1 frizzled class receptor 1 2.75208
TARBP1 TAR (HIV-1) RNA binding protein 1 2.75208
C9ORF57 chromosome 9 open reading frame 57 2.75208
ZNF703 zinc finger protein 703 2.75208
RBFOX3 RNA binding protein, fox-1 homolog (C. elegans) 3 2.75208
EXTL1 exostosin-like glycosyltransferase 1 2.75208
RANBP3L RAN binding protein 3-like 2.75208
TAF7L TAF7-like RNA polymerase II, TATA box binding protein (TBP)-associated factor, 50kDa 2.75208
NIPAL4 NIPA-like domain containing 4 2.75208
ODF1 outer dense fiber of sperm tails 1 2.75208
ENTPD8 ectonucleoside triphosphate diphosphohydrolase 8 2.75208
C11ORF16 chromosome 11 open reading frame 16 2.75208
GLT1D1 glycosyltransferase 1 domain containing 1 2.75208
WNT7A wingless-type MMTV integration site family, member 7A 2.75208
TBC1D10C TBC1 domain family, member 10C 2.75208
PPP1R14D protein phosphatase 1, regulatory (inhibitor) subunit 14D 2.75208
C20ORF144 chromosome 20 open reading frame 144 2.75208
IGF2 insulin-like growth factor 2 2.75208
KLK5 kallikrein-related peptidase 5 2.75208
UTS2R urotensin 2 receptor 2.75208
EFCAB3 EF-hand calcium binding domain 3 2.75208
KCNV1 potassium channel, voltage gated modifier subfamily V, member 1 2.75208
EXOSC2 exosome component 2 2.75208
MAEL maelstrom spermatogenic transposon silencer 2.75208
ITGAD integrin, alpha D 2.75208
RNASE11 ribonuclease, RNase A family, 11 (non-active) 2.75208
ZNF831 zinc finger protein 831 2.75208
RIIAD1 regulatory subunit of type II PKA R-subunit (RIIa) domain containing 1 2.75208
MSANTD1 Myb/SANT-like DNA-binding domain containing 1 2.75208
FOXS1 forkhead box S1 2.75208
ANXA8 annexin A8 2.75208
ZC3HAV1L zinc finger CCCH-type, antiviral 1-like 2.75208
ANGPTL5 angiopoietin-like 5 2.75208
NR1D1 nuclear receptor subfamily 1, group D, member 1 2.75208
TMEM88 transmembrane protein 88 2.75208
PHACTR3 phosphatase and actin regulator 3 2.75208
SLC36A3 solute carrier family 36, member 3 2.75208
VWC2L von Willebrand factor C domain containing protein 2-like 2.75208
GPD1 glycerol-3-phosphate dehydrogenase 1 (soluble) 2.75208
NRG1 neuregulin 1 2.75208
PASD1 PAS domain containing 1 2.75208
SMPD1 sphingomyelin phosphodiesterase 1, acid lysosomal 2.75208
GJB6 gap junction protein, beta 6, 30kDa 2.75208
MYADML2 myeloid-associated differentiation marker-like 2 2.75208
DMRT1 doublesex and mab-3 related transcription factor 1 2.75208
SLC7A4 solute carrier family 7, member 4 2.75208
CARNS1 carnosine synthase 1 2.75208
NR5A1 nuclear receptor subfamily 5, group A, member 1 2.75208
PXT1 peroxisomal, testis specific 1 2.75208
LYZ lysozyme 2.75208
OR14J1 olfactory receptor, family 14, subfamily J, member 1 2.75208
CTSG cathepsin G 2.75208
CYP2D6 cytochrome P450, family 2, subfamily D, polypeptide 6 2.75208
LRRC74A leucine rich repeat containing 74A 2.75208
PTPN7 protein tyrosine phosphatase, non-receptor type 7 2.75208
CFAP126 cilia and flagella associated protein 126 2.75208
RBBP8NL RBBP8 N-terminal like 2.75208
NKX6-3 NK6 homeobox 3 2.75208
TEX35 testis expressed 35 2.75208
VPREB3 pre-B lymphocyte 3 2.75208
MBTPS2 membrane-bound transcription factor peptidase, site 2 2.74127
CSRP1 cysteine and glycine-rich protein 1 2.70026
ARSI arylsulfatase family, member I 2.66834
ASB18 ankyrin repeat and SOCS box containing 18 2.66834
STXBP5L syntaxin binding protein 5-like 2.62312
SYNE1 spectrin repeat containing, nuclear envelope 1 2.60949
CCDC68 coiled-coil domain containing 68 2.55969
UBTD1 ubiquitin domain containing 1 2.55086
QSOX1 quiescin Q6 sulfhydryl oxidase 1 2.54614
DLEC1 deleted in lung and esophageal cancer 1 2.54169
ERLIN2 ER lipid raft associated 2 2.51918
H1-1 H1.1 linker histone, cluster member 2.50697
GATC glutamyl-tRNA(Gln) amidotransferase, subunit C 2.50697
CDC40 cell division cycle 40 2.47275
CARD10 caspase recruitment domain family, member 10 2.44344
PGRMC2 progesterone receptor membrane component 2 2.41338
OLFML1 olfactomedin-like 1 2.39182
SCN4A sodium channel, voltage gated, type IV alpha subunit 2.36861
NECAP1 NECAP endocytosis associated 1 2.35418
RPS2 ribosomal protein S2 2.31834
VWF von Willebrand factor 2.31169
TUBGCP3 tubulin, gamma complex associated protein 3 2.30635
TGFB3 transforming growth factor, beta 3 2.2934
MAP6 microtubule-associated protein 6 2.2934
NUF2 NUF2, NDC80 kinetochore complex component 2.29269
ILRUN inflammation and lipid regulator with UBA-like and NBR1-like domains 2.28145
U2AF1L4 U2 small nuclear RNA auxiliary factor 1-like 4 2.27955
SHROOM3 shroom family member 3 2.27382
SIRT4 sirtuin 4 2.27248
RBM34 RNA binding motif protein 34 2.25511
RO60 Ro60, Y RNA binding protein 2.24517
ALLC allantoicase 2.24517
C1ORF146 chromosome 1 open reading frame 146 2.2359
SMIM11 small integral membrane protein 11 2.23419
ADNP2 ADNP homeobox 2 2.17379
COL6A2 collagen, type VI, alpha 2 2.15651
URB2 URB2 ribosome biogenesis 2 homolog (S. cerevisiae) 2.125
DIMT1 DIM1 dimethyladenosine transferase 1 homolog (S. cerevisiae) 2.10583
ZDHHC12 zinc finger, DHHC-type containing 12 2.09334
EPHX3 epoxide hydrolase 3 2.09088
PEPD peptidase D 2.07551
PRH1 proline-rich protein HaeIII subfamily 1 2.07551
SARS2 seryl-tRNA synthetase 2, mitochondrial 2.07284
LLGL1 lethal giant larvae homolog 1 (Drosophila) 2.07235
RIGI RNA sensor RIG-I 2.06924
CCNP cyclin P 2.06924
ZNF397 zinc finger protein 397 2.06724
SIAH1 siah E3 ubiquitin protein ligase 1 2.06636
OXNAD1 oxidoreductase NAD-binding domain containing 1 2.04058
CASTOR2 cytosolic arginine sensor for mTORC1 subunit 2 2.02898
BEST2 bestrophin 2 2.02005
PDCD2 programmed cell death 2 2.02
RILPL1 Rab interacting lysosomal protein-like 1 2.01994
TIGD4 tigger transposable element derived 4 2.01433
EXOC1 exocyst complex component 1 2.0137
KAT5 K(lysine) acetyltransferase 5 2.00373

decreased expression

Symbol Name Standardized Value
PTK6 protein tyrosine kinase 6 -2.75208
SULT1C2 sulfotransferase family, cytosolic, 1C, member 2 -2.75208
MYOT myotilin -2.75208
SPATA32 spermatogenesis associated 32 -2.75208
RAB40A RAB40A, member RAS oncogene family -2.75208
ADGRG1 adhesion G protein-coupled receptor G1 -2.75208
OR2A25 olfactory receptor, family 2, subfamily A, member 25 -2.75208
C1ORF87 chromosome 1 open reading frame 87 -2.75208
SHOX short stature homeobox -2.75208
NPIPA2 nuclear pore complex interacting protein family, member A2 -2.75208
GALNT15 polypeptide N-acetylgalactosaminyltransferase 15 -2.75208
IZUMO1 izumo sperm-egg fusion 1 -2.75208
NKPD1 NTPase, KAP family P-loop domain containing 1 -2.75208
DDX43 DEAD (Asp-Glu-Ala-Asp) box polypeptide 43 -2.75208
SLC44A4 solute carrier family 44, member 4 -2.75208
CEBPD CCAAT/enhancer binding protein (C/EBP), delta -2.75208
FGF9 fibroblast growth factor 9 -2.75208
LTB lymphotoxin beta (TNF superfamily, member 3) -2.75208
SPINT3 serine peptidase inhibitor, Kunitz type, 3 -2.75208
HMGXB3 HMG box domain containing 3 -2.75208
LTB4R2 leukotriene B4 receptor 2 -2.75208
CIITA class II, major histocompatibility complex, transactivator -2.75208
SPMIP10 sperm microtubule inner protein 10 -2.75208
FUBP3 far upstream element (FUSE) binding protein 3 -2.75208
CD200R1 CD200 receptor 1 -2.75208
MYCBP2 MYC binding protein 2, E3 ubiquitin protein ligase -2.75208
ANKS4B ankyrin repeat and sterile alpha motif domain containing 4B -2.75208
ARMC5 armadillo repeat containing 5 -2.75208
PLPPR5 phospholipid phosphatase related 5 -2.75208
NFKB1 nuclear factor of kappa light polypeptide gene enhancer in B-cells 1 -2.70855
INKA2 inka box actin regulator 2 -2.70855
SNX31 sorting nexin 31 -2.66
RLN1 relaxin 1 -2.64073
RSPH1 radial spoke head 1 homolog (Chlamydomonas) -2.64073
SLC35E3 solute carrier family 35, member E3 -2.6141
SMAD9 SMAD family member 9 -2.51655
H3C7 H3 clustered histone 7 -2.4794
DST dystonin -2.47714
USP14 ubiquitin specific peptidase 14 (tRNA-guanine transglycosylase) -2.44957
PAIP2 poly(A) binding protein interacting protein 2 -2.44957
FIS1 fission 1 (mitochondrial outer membrane) homolog (S. cerevisiae) -2.43863
SKIL SKI-like proto-oncogene -2.43349
ACSF3 acyl-CoA synthetase family member 3 -2.4166
TMEM116 transmembrane protein 116 -2.41355
CUL4A cullin 4A -2.37546
CXCL17 chemokine (C-X-C motif) ligand 17 -2.35418
PCDHGA5 protocadherin gamma subfamily A, 5 -2.35418
DISC1 disrupted in schizophrenia 1 -2.35418
F13A1 coagulation factor XIII, A1 polypeptide -2.35418
TTF2 transcription termination factor, RNA polymerase II -2.32896
NT5C2 5'-nucleotidase, cytosolic II -2.32896
RBX1 ring-box 1, E3 ubiquitin protein ligase -2.28127
TSSK3 testis-specific serine kinase 3 -2.27618
POU2F3 POU class 2 homeobox 3 -2.27618
EFNB1 ephrin-B1 -2.27618
FBP1 fructose-1,6-bisphosphatase 1 -2.27489
ZNF324 zinc finger protein 324 -2.27419
SMIM24 small integral membrane protein 24 -2.16056
NAXD NAD(P)HX dehydratase -2.15416
NTF3 neurotrophin 3 -2.15003
TAF1D TATA box binding protein (TBP)-associated factor, RNA polymerase I, D, 41kDa -2.14776
SCAF4 SR-related CTD-associated factor 4 -2.12105
SUMO4 small ubiquitin-like modifier 4 -2.10785
DDX52 DEAD (Asp-Glu-Ala-Asp) box polypeptide 52 -2.10785
GSDMD gasdermin D -2.10785
NOPCHAP1 NOP protein chaperone 1 -2.10399
ZNF219 zinc finger protein 219 -2.09334
RICTOR RPTOR independent companion of MTOR, complex 2 -2.09334
GTF3A general transcription factor IIIA -2.09334
NOP16 NOP16 nucleolar protein -2.07763
RHEBL1 Ras homolog enriched in brain like 1 -2.07235
TCTN1 tectonic family member 1 -2.06636
NBN nibrin -2.06631
DIAPH1 diaphanous-related formin 1 -2.06526
BPNT1 3'(2'), 5'-bisphosphate nucleotidase 1 -2.05248
TTC32 tetratricopeptide repeat domain 32 -2.05153
OR52N2 olfactory receptor, family 52, subfamily N, member 2 -2.04385
CDHR2 cadherin-related family member 2 -2.04385
NANS N-acetylneuraminic acid synthase -2.04312
TMEFF2 transmembrane protein with EGF-like and two follistatin-like domains 2 -2.01769
CDRT4 CMT1A duplicated region transcript 4 -2.01769
TRAPPC8 trafficking protein particle complex 8 -2.01433
IREB2 iron-responsive element binding protein 2 -2.01017
CD72 CD72 molecule -2.00833
MEGF10 multiple EGF-like-domains 10 -2.00606
SKAP2 src kinase associated phosphoprotein 2 -2.00169