SETD4 Gene Set

Dataset CM4AI KOLF21J CRISPRi Gene Perturbation Atlas
Category transcriptomics
Type gene perturbation
Description SET domain containing 4| (NCBI Entrez Gene Database, 54093)
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Genes

373 genes differentially expressed following the SETD4 gene perturbation from the CM4AI KOLF21J CRISPRi Gene Perturbation Atlas.

increased expression

Symbol Name Standardized Value
PCDHB11 protocadherin beta 11 3.16358
DUXB double homeobox B 3.16358
IZUMO3 IZUMO family member 3 3.16358
NANOS3 nanos homolog 3 (Drosophila) 3.16358
MGAM2 maltase-glucoamylase 2 (putative) 3.16358
GFRA3 GDNF family receptor alpha 3 3.16358
BTLA B and T lymphocyte associated 3.16358
OSGIN1 oxidative stress induced growth inhibitor 1 3.16358
CCL5 chemokine (C-C motif) ligand 5 3.16358
LYVE1 lymphatic vessel endothelial hyaluronan receptor 1 3.16358
TYRP1 tyrosinase-related protein 1 3.16358
GIP gastric inhibitory polypeptide 3.16358
FAM167A family with sequence similarity 167, member A 3.16358
SLC6A2 solute carrier family 6 (neurotransmitter transporter), member 2 3.16358
MAP1LC3C microtubule-associated protein 1 light chain 3 gamma 3.16358
LOC390937 Ets2 repressor factor-like 3.16358
DNMT3L DNA (cytosine-5-)-methyltransferase 3-like 3.16358
HBA2 hemoglobin, alpha 2 3.16358
ARHGDIB Rho GDP dissociation inhibitor (GDI) beta 3.16358
SLC22A16 solute carrier family 22 (organic cation/carnitine transporter), member 16 3.16358
SRL sarcalumenin 3.16358
TMEM212 transmembrane protein 212 3.16358
HRH4 histamine receptor H4 3.16358
MYO7B myosin VIIB 3.16358
GABRA1 gamma-aminobutyric acid (GABA) A receptor, alpha 1 3.16358
SSTR5 somatostatin receptor 5 3.16358
PNOC prepronociceptin 3.16358
SPHK1 sphingosine kinase 1 3.16358
KLLN killin, p53-regulated DNA replication inhibitor 3.16358
CSNK2A3 casein kinase 2, alpha 3 polypeptide 3.16358
ITIH2 inter-alpha-trypsin inhibitor heavy chain 2 3.16358
PRR22 proline rich 22 3.16358
LVRN laeverin 3.16358
FAM9B family with sequence similarity 9, member B 3.16358
SLC10A6 solute carrier family 10 (sodium/bile acid cotransporter), member 6 3.16358
ARSH arylsulfatase family, member H 3.16358
S100A1 S100 calcium binding protein A1 3.16358
LGI1 leucine-rich, glioma inactivated 1 3.16358
MAGED4 melanoma antigen family D4 3.16358
SFXN3 sideroflexin 3 3.16358
GIMAP8 GTPase, IMAP family member 8 3.16358
SERF1A small EDRK-rich factor 1A (telomeric) 3.16358
RFPL3 ret finger protein-like 3 3.16358
C9ORF152 chromosome 9 open reading frame 152 3.16358
TMEM71 transmembrane protein 71 3.16358
LCN10 lipocalin 10 3.16358
SPINK6 serine peptidase inhibitor, Kazal type 6 3.16358
KCNE1 potassium channel, voltage gated subfamily E regulatory beta subunit 1 3.16358
KCNE3 potassium channel, voltage gated subfamily E regulatory beta subunit 3 3.16358
PFKFB1 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 1 3.16358
C4ORF17 chromosome 4 open reading frame 17 3.16358
LOC107986837 uncharacterized LOC107986837 3.16358
PNMA8B PNMA family member 8B 3.16358
STING1 stimulator of interferon response cGAMP interactor 1 3.16358
RAG1 recombination activating gene 1 3.16358
AVPR1A arginine vasopressin receptor 1A 3.16358
GPX5 glutathione peroxidase 5 3.16358
TAS2R60 taste receptor, type 2, member 60 3.16358
MYH6 myosin, heavy chain 6, cardiac muscle, alpha 3.16358
FRG2C FSHD region gene 2 family, member C 3.16358
FIMP1 fertilization-influencing membrane protein 1 3.16358
TMEM40 transmembrane protein 40 3.16358
CCDC9B coiled-coil domain containing 9B 3.16358
PLAAT2 phospholipase A and acyltransferase 2 3.16358
AJM1 apical junction component 1 homolog 3.16358
SPMAP2L sperm microtubule associated protein 2 like 3.16358
SMIM47 small integral membrane protein 47 3.16358
NOTCH2NLB notch 2 N-terminal like B 3.16358
LOC124902436 talanin 3.16358
SRARP steroid receptor associated and regulated protein 3.16358
IHO1 interactor of HORMAD1 1 3.16358
TMEM225B transmembrane protein 225B 3.16358
CBY2 chibby family member 2 3.16358
CFAP157 cilia and flagella associated protein 157 3.16358
CCDC187 coiled-coil domain containing 187 3.16358
RAB36 RAB36, member RAS oncogene family 3.16358
TSPAN1 tetraspanin 1 3.16358
ZNF575 zinc finger protein 575 3.16358
PTP4A1 protein tyrosine phosphatase type IVA, member 1 3.16358
CATSPERD catsper channel auxiliary subunit delta 3.16358
MEOX2 mesenchyme homeobox 2 3.16358
CKM creatine kinase, muscle 3.16358
OLAH oleoyl-ACP hydrolase 3.16358
ZSWIM2 zinc finger, SWIM-type containing 2 3.16358
CCR6 chemokine (C-C motif) receptor 6 3.16358
NXPE1 neurexophilin and PC-esterase domain family, member 1 3.16358
TRIM60 tripartite motif containing 60 3.16358
TLR7 toll-like receptor 7 3.16358
CREB3L3 cAMP responsive element binding protein 3-like 3 3.16358
MYOC myocilin, trabecular meshwork inducible glucocorticoid response 3.16358
CFC1 cripto, FRL-1, cryptic family 1 3.16358
REP15 RAB15 effector protein 3.16358
F5 coagulation factor V (proaccelerin, labile factor) 3.16358
DYNAP dynactin associated protein 3.16358
SOAT2 sterol O-acyltransferase 2 3.16358
OOSP2 oocyte secreted protein 2 3.16358
BARX1 BARX homeobox 1 3.16358
TACR2 tachykinin receptor 2 3.16358
CACNG4 calcium channel, voltage-dependent, gamma subunit 4 3.16358
ATP2B3 ATPase, Ca++ transporting, plasma membrane 3 3.16358
CLDN2 claudin 2 3.16358
TREH trehalase (brush-border membrane glycoprotein) 3.16358
SPEF1 sperm flagellar 1 3.16358
NCR3LG1 natural killer cell cytotoxicity receptor 3 ligand 1 3.16358
LRRC36 leucine rich repeat containing 36 3.16358
OCM oncomodulin 3.16358
TF transferrin 3.16358
LPAR5 lysophosphatidic acid receptor 5 3.16358
NUTM2D NUT family member 2D 3.16358
DDX4 DEAD (Asp-Glu-Ala-Asp) box polypeptide 4 3.16358
FOXS1 forkhead box S1 3.16358
PPEF2 protein phosphatase, EF-hand calcium binding domain 2 3.16358
RBM20 RNA binding motif protein 20 3.16358
YWHAB tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, beta 3.16358
AQP7 aquaporin 7 3.16358
PATE2 prostate and testis expressed 2 3.16358
SPHKAP SPHK1 interactor, AKAP domain containing 3.16358
CLPSL2 colipase-like 2 3.16358
PIRT phosphoinositide-interacting regulator of transient receptor potential channels 3.16358
EGR2 early growth response 2 3.16358
MYF6 myogenic factor 6 (herculin) 3.16358
C11ORF16 chromosome 11 open reading frame 16 3.16358
NPFFR1 neuropeptide FF receptor 1 3.16358
TDRD12 tudor domain containing 12 3.16358
RNASE11 ribonuclease, RNase A family, 11 (non-active) 3.16358
F11 coagulation factor XI 3.16358
EMP1 epithelial membrane protein 1 3.16358
CTAGE9 CTAGE family, member 9 3.16358
PCDHGA7 protocadherin gamma subfamily A, 7 3.16358
RSPH10B2 radial spoke head 10 homolog B2 (Chlamydomonas) 3.16358
COMP cartilage oligomeric matrix protein 3.16358
ZNF541 zinc finger protein 541 3.16358
OPRK1 opioid receptor, kappa 1 3.16358
GAB4 GRB2-associated binding protein family, member 4 3.16358
CCL25 chemokine (C-C motif) ligand 25 3.16358
FBXO47 F-box protein 47 3.16358
CDH10 cadherin 10, type 2 (T2-cadherin) 3.16358
B4GALNT1 beta-1,4-N-acetyl-galactosaminyl transferase 1 3.16358
CHAD chondroadherin 3.16358
TMPRSS13 transmembrane protease, serine 13 3.16358
PLA2G5 phospholipase A2, group V 3.16358
OR10G3 olfactory receptor, family 10, subfamily G, member 3 3.16358
ICAM4 intercellular adhesion molecule 4 (Landsteiner-Wiener blood group) 3.16358
OR14A2 olfactory receptor, family 14, subfamily A, member 2 3.16358
FAIM2 Fas apoptotic inhibitory molecule 2 3.16358
ALDH3A1 aldehyde dehydrogenase 3 family, member A1 3.16358
GPR150 G protein-coupled receptor 150 3.16358
OR13G1 olfactory receptor, family 13, subfamily G, member 1 3.16358
SLC25A34 solute carrier family 25, member 34 3.16358
ADAM29 ADAM metallopeptidase domain 29 3.16358
RAB7B RAB7B, member RAS oncogene family 3.16358
ANXA1 annexin A1 3.16358
ADAP1 ArfGAP with dual PH domains 1 3.16358
PRG2 proteoglycan 2, bone marrow (natural killer cell activator, eosinophil granule major basic protein) 3.16358
CDH22 cadherin 22, type 2 3.16358
SYNGR4 synaptogyrin 4 3.16358
SYTL4 synaptotagmin-like 4 3.16358
CYP2J2 cytochrome P450, family 2, subfamily J, polypeptide 2 3.16358
SLC4A1 solute carrier family 4 (anion exchanger), member 1 (Diego blood group) 3.16358
THEM5 thioesterase superfamily member 5 3.16358
PASD1 PAS domain containing 1 3.16358
TMEM31 transmembrane protein 31 3.16358
YBX3 Y box binding protein 3 3.16358
GOLGA8H golgin A8 family, member H 3.16358
LHX5 LIM homeobox 5 3.16358
A1CF APOBEC1 complementation factor 3.16358
GPR179 G protein-coupled receptor 179 3.16358
YBX1 Y box binding protein 1 3.16321
APP-DT APP divergent transcript 3.12378
ERICH5 glutamate-rich 5 3.12378
PPP2R2A protein phosphatase 2, regulatory subunit B, alpha 3.08949
SDHAF1 succinate dehydrogenase complex assembly factor 1 3.06158
PCCA propionyl CoA carboxylase, alpha polypeptide 3.06158
PRDX6 peroxiredoxin 6 3.04842
IL2RB interleukin 2 receptor, beta 2.97542
MRPL17 mitochondrial ribosomal protein L17 2.97204
RANGRF RAN guanine nucleotide release factor 2.89264
POLR1A polymerase (RNA) I polypeptide A, 194kDa 2.86737
POLDIP3 polymerase (DNA-directed), delta interacting protein 3 2.8625
H4C16 H4 histone 16 2.85848
MTBP MDM2 binding protein 2.82291
UBE2E1 ubiquitin-conjugating enzyme E2E 1 2.81648
NHEJ1 nonhomologous end-joining factor 1 2.81648
SNRPD2 small nuclear ribonucleoprotein D2 polypeptide 16.5kDa 2.75703
SPIN3 spindlin family, member 3 2.74738
PYGO1 pygopus family PHD finger 1 2.74717
CR2 complement component (3d/Epstein Barr virus) receptor 2 2.74717
BCL10 B-cell CLL/lymphoma 10 2.73004
ADPRM ADP-ribose/CDP-alcohol diphosphatase, manganese-dependent 2.73004
TBC1D10B TBC1 domain family, member 10B 2.73004
MRE11 MRE11 homolog, double strand break repair nuclease 2.64161
CMKLR1 chemerin chemokine-like receptor 1 2.59845
DIP2A DIP2 disco-interacting protein 2 homolog A (Drosophila) 2.58065
DISP2 dispatched homolog 2 (Drosophila) 2.56587
GLYATL1 glycine-N-acyltransferase-like 1 2.5633
AQR aquarius intron-binding spliceosomal factor 2.56253
DDX18 DEAD (Asp-Glu-Ala-Asp) box polypeptide 18 2.53988
IGSF5 immunoglobulin superfamily, member 5 2.50993
RAB3B RAB3B, member RAS oncogene family 2.47569
DRICH1 aspartate-rich 1 2.46726
MAP3K7CL MAP3K7 C-terminal like 2.46726
UBB ubiquitin B 2.43751
RDH13 retinol dehydrogenase 13 (all-trans/9-cis) 2.43291
FANCC Fanconi anemia, complementation group C 2.42191
NOX4 NADPH oxidase 4 2.41533
UQCRQ ubiquinol-cytochrome c reductase, complex III subunit VII, 9.5kDa 2.40976
BAHD1 bromo adjacent homology domain containing 1 2.37234
BTF3 basic transcription factor 3 2.36429
SHE Src homology 2 domain containing E 2.36429
SCN4B sodium channel, voltage gated, type IV beta subunit 2.36429
INSYN2B inhibitory synaptic factor family member 2B 2.36429
ADRA2B adrenoceptor alpha 2B 2.36429
MYOZ1 myozenin 1 2.36429
PPP1R3C protein phosphatase 1, regulatory subunit 3C 2.36429
CACNB3 calcium channel, voltage-dependent, beta 3 subunit 2.36429
SLC16A1 solute carrier family 16 (monocarboxylate transporter), member 1 2.36079
SLC35A2 solute carrier family 35 (UDP-galactose transporter), member A2 2.34873
STAMBPL1 STAM binding protein-like 1 2.33339
KRT10 keratin 10, type I 2.30547
FRMPD3 FERM and PDZ domain containing 3 2.29955
H2AC11 H2A clustered histone 11 2.26336
PSMD12 proteasome (prosome, macropain) 26S subunit, non-ATPase, 12 2.26336
NVL nuclear VCP-like 2.26336
LSAMP limbic system-associated membrane protein 2.25047
RMP64 ribonuclease MRP subunit p64 2.24643
PLXNC1 plexin C1 2.24643
SHC2 SHC (Src homology 2 domain containing) transforming protein 2 2.21603
MTAP methylthioadenosine phosphorylase 2.20962
GCC2 GRIP and coiled-coil domain containing 2 2.19058
CSNK1D casein kinase 1, delta 2.18786
PMS1 PMS1 postmeiotic segregation increased 1 (S. cerevisiae) 2.16899
SENP2 SUMO1/sentrin/SMT3 specific peptidase 2 2.15357
ERVMER34-1 endogenous retrovirus group MER34, member 1 2.13432
TRIP12 thyroid hormone receptor interactor 12 2.12001
CYBA cytochrome b-245, alpha polypeptide 2.11097
GID8 GID complex subunit 8 2.11042
FANK1 fibronectin type III and ankyrin repeat domains 1 2.11042
PFDN5 prefoldin subunit 5 2.10677
ZNF28 zinc finger protein 28 2.10094
ZNF268 zinc finger protein 268 2.10094
MAPK3 mitogen-activated protein kinase 3 2.09537
NUDT3 nudix (nucleoside diphosphate linked moiety X)-type motif 3 2.08817
NAF1 nuclear assembly factor 1 ribonucleoprotein 2.08515
MAP3K8 mitogen-activated protein kinase kinase kinase 8 2.08515
DNAJA2 DnaJ (Hsp40) homolog, subfamily A, member 2 2.07703
CELF2 CUGBP, Elav-like family member 2 2.07595
ZNHIT1 zinc finger, HIT-type containing 1 2.06145
PPP1R11 protein phosphatase 1, regulatory (inhibitor) subunit 11 2.057
CCDC93 coiled-coil domain containing 93 2.057
ATXN7L3 ataxin 7-like 3 2.03817
SLC3A2 solute carrier family 3 (amino acid transporter heavy chain), member 2 2.02498
ZNF599 zinc finger protein 599 2.01626
SKA2 spindle and kinetochore associated complex subunit 2 2.01254

decreased expression

Symbol Name Standardized Value
LOC124904542 uncharacterized LOC124904542 -3.16358
RHBDL2 rhomboid, veinlet-like 2 (Drosophila) -3.16358
TAC1 tachykinin, precursor 1 -3.16358
ENTPD2 ectonucleoside triphosphate diphosphohydrolase 2 -3.16358
MIB2 mindbomb E3 ubiquitin protein ligase 2 -3.16358
CLIC2 chloride intracellular channel 2 -3.16358
CORO2A coronin, actin binding protein, 2A -3.16358
TLE4 transducin-like enhancer of split 4 -3.10961
WDR1 WD repeat domain 1 -2.97542
FAM184A family with sequence similarity 184, member A -2.93118
ELOVL2 ELOVL fatty acid elongase 2 -2.93118
DRC10 dynein regulatory complex subunit 10 -2.91314
PRRC2A proline-rich coiled-coil 2A -2.83367
IPO9 importin 9 -2.81648
RNASEH2B ribonuclease H2, subunit B -2.75813
TECPR1 tectonin beta-propeller repeat containing 1 -2.75703
OR10A2 olfactory receptor, family 10, subfamily A, member 2 -2.73004
TSPAN8 tetraspanin 8 -2.73004
AVP arginine vasopressin -2.73004
ATG4A autophagy related 4A, cysteine peptidase -2.73004
FMO3 flavin containing monooxygenase 3 -2.73004
MYL5 myosin, light chain 5, regulatory -2.73004
TNFSF9 tumor necrosis factor (ligand) superfamily, member 9 -2.73004
IL17C interleukin 17C -2.73004
NXPH3 neurexophilin 3 -2.73004
CYP4Z1 cytochrome P450, family 4, subfamily Z, polypeptide 1 -2.73004
CORO6 coronin 6 -2.73004
MMP21 matrix metallopeptidase 21 -2.73004
PLK5 polo-like kinase 5 -2.73004
VSTM2A V-set and transmembrane domain containing 2A -2.73004
PGAM2 phosphoglycerate mutase 2 (muscle) -2.73004
CHADL chondroadherin-like -2.73004
C19ORF73 chromosome 19 open reading frame 73 -2.73004
MYCT1 myc target 1 -2.73004
CSAG3 CSAG family, member 3 -2.73004
PTGER3 prostaglandin E receptor 3 (subtype EP3) -2.73004
RPL3L ribosomal protein L3-like -2.73004
TTLL2 tubulin tyrosine ligase-like family member 2 -2.73004
HBA1 hemoglobin, alpha 1 -2.73004
UPK1B uroplakin 1B -2.73004
HSPA1B heat shock 70kDa protein 1B -2.73004
FKBP1C FK506 binding protein 1C -2.73004
SLC2A9 solute carrier family 2 (facilitated glucose transporter), member 9 -2.73004
AZIN2 antizyme inhibitor 2 -2.73004
HLA-DOB major histocompatibility complex, class II, DO beta -2.73004
GDPD3 glycerophosphodiester phosphodiesterase domain containing 3 -2.73004
NBPF26 neuroblastoma breakpoint family, member 26 -2.73004
PKLR pyruvate kinase, liver and RBC -2.73004
RIOX2 ribosomal oxygenase 2 -2.68307
TMEM115 transmembrane protein 115 -2.67893
IGSF11 immunoglobulin superfamily, member 11 -2.65787
RIC1 RAB6A GEF complex partner 1 -2.65787
VPS18 vacuolar protein sorting 18 homolog (S. cerevisiae) -2.65772
ITGB5 integrin, beta 5 -2.643
IL13RA1 interleukin 13 receptor, alpha 1 -2.60191
UBR5 ubiquitin protein ligase E3 component n-recognin 5 -2.597
METAP2 methionyl aminopeptidase 2 -2.59375
SEC14L4 SEC14-like 4 (S. cerevisiae) -2.59375
CHRNA3 cholinergic receptor, nicotinic, alpha 3 (neuronal) -2.59375
TAC4 tachykinin 4 (hemokinin) -2.57308
BAZ1B bromodomain adjacent to zinc finger domain, 1B -2.57255
TTLL11 tubulin tyrosine ligase-like family member 11 -2.5633
NTNG2 netrin G2 -2.5439
PROKR2 prokineticin receptor 2 -2.5439
TRAF1 TNF receptor-associated factor 1 -2.5439
SPATA2L spermatogenesis associated 2-like -2.5439
EFCAB5 EF-hand calcium binding domain 5 -2.5439
NBPF10 neuroblastoma breakpoint family, member 10 -2.5439
ASIC1 acid sensing (proton gated) ion channel 1 -2.5439
SLC5A2 solute carrier family 5 (sodium/glucose cotransporter), member 2 -2.5439
MRPS31 mitochondrial ribosomal protein S31 -2.53775
FMNL2 formin-like 2 -2.50993
CEP104 centrosomal protein 104kDa -2.49831
EHD3 EH-domain containing 3 -2.48774
YIPF5 Yip1 domain family, member 5 -2.4856
SMCHD1 structural maintenance of chromosomes flexible hinge domain containing 1 -2.44549
GAR1 GAR1 ribonucleoprotein -2.43946
ADCY5 adenylate cyclase 5 -2.4198
LRP3 low density lipoprotein receptor-related protein 3 -2.4034
ZNF688 zinc finger protein 688 -2.39644
MARCHF10 membrane associated ring-CH-type finger 10 -2.39644
DNAJC24 DnaJ (Hsp40) homolog, subfamily C, member 24 -2.38006
TRO trophinin -2.37686
DBP D site of albumin promoter (albumin D-box) binding protein -2.28566
MAP3K3 mitogen-activated protein kinase kinase kinase 3 -2.26336
SPSB3 splA/ryanodine receptor domain and SOCS box containing 3 -2.25047
WFS1 Wolfram syndrome 1 (wolframin) -2.25047
FOXK2 forkhead box K2 -2.24643
VTI1B vesicle transport through interaction with t-SNAREs 1B -2.24035
DUSP1 dual specificity phosphatase 1 -2.21997
PDK2 pyruvate dehydrogenase kinase, isozyme 2 -2.21603
QARS1 glutaminyl-tRNA synthetase 1 -2.20705
AKTIP AKT interacting protein -2.20361
ANP32E acidic (leucine-rich) nuclear phosphoprotein 32 family, member E -2.20302
PPP6R2 protein phosphatase 6, regulatory subunit 2 -2.19901
CERS5 ceramide synthase 5 -2.19033
MRPL42 mitochondrial ribosomal protein L42 -2.17179
SOX7 SRY (sex determining region Y)-box 7 -2.15925
TCP11L2 t-complex 11, testis-specific-like 2 -2.15925
DNAJC28 DnaJ (Hsp40) homolog, subfamily C, member 28 -2.15925
NACAD NAC alpha domain containing -2.15925
ZNF701 zinc finger protein 701 -2.15925
ZSCAN30 zinc finger and SCAN domain containing 30 -2.15321
GMCL1 germ cell-less, spermatogenesis associated 1 -2.15303
NLGN4X neuroligin 4, X-linked -2.14204
CDYL chromodomain protein, Y-like -2.14101
TANK TRAF family member-associated NFKB activator -2.10094
CAT catalase -2.08817
MACIR macrophage immunometabolism regulator -2.08515
AK9 adenylate kinase 9 -2.07805
CHPF2 chondroitin polymerizing factor 2 -2.07805
NOXRED1 NADP-dependent oxidoreductase domain containing 1 -2.0742
TP53TG5 TP53 target 5 -2.0742
EEF1AKMT3 EEF1A lysine methyltransferase 3 -2.0742
AADACL3 arylacetamide deacetylase-like 3 -2.0742
CD79B CD79b molecule, immunoglobulin-associated beta -2.0742
TRIM59 tripartite motif containing 59 -2.057
KLHL24 kelch-like family member 24 -2.04904
PREX1 phosphatidylinositol-3,4,5-trisphosphate-dependent Rac exchange factor 1 -2.03911
LRMDA leucine rich melanocyte differentiation associated -2.03386