SETD6 Gene Set

Dataset CM4AI KOLF21J CRISPRi Gene Perturbation Atlas
Category transcriptomics
Type gene perturbation
Description SET domain containing 6| (NCBI Entrez Gene Database, 79918)
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Genes

347 genes differentially expressed following the SETD6 gene perturbation from the CM4AI KOLF21J CRISPRi Gene Perturbation Atlas.

increased expression

Symbol Name Standardized Value
XPNPEP2 X-prolyl aminopeptidase (aminopeptidase P) 2, membrane-bound 3.34771
PCDHB7 protocadherin beta 7 3.34771
PNMA5 paraneoplastic Ma antigen family member 5 3.34771
UCP1 uncoupling protein 1 (mitochondrial, proton carrier) 3.34771
CSTL1 cystatin-like 1 3.34771
PTH2 parathyroid hormone 2 3.34771
PAX3 paired box 3 3.34771
RSPO1 R-spondin 1 3.34771
MYOM3 myomesin 3 3.34771
HCRTR2 hypocretin (orexin) receptor 2 3.34771
CA6 carbonic anhydrase VI 3.34771
ADIPOQ adiponectin, C1Q and collagen domain containing 3.34771
TXNDC2 thioredoxin domain containing 2 (spermatozoa) 3.34771
PLIN4 perilipin 4 3.34771
LAPTM5 lysosomal protein transmembrane 5 3.34771
CD6 CD6 molecule 3.34771
SLC6A4 solute carrier family 6 (neurotransmitter transporter), member 4 3.34771
SLC6A7 solute carrier family 6 (neurotransmitter transporter), member 7 3.34771
FGD2 FYVE, RhoGEF and PH domain containing 2 3.34771
WDR87 WD repeat domain 87 3.34771
COLEC10 collectin sub-family member 10 (C-type lectin) 3.34771
ADGRE3 adhesion G protein-coupled receptor E3 3.34771
KNG1 kininogen 1 3.34771
SERPINA11 serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 11 3.34771
UNC45B unc-45 homolog B (C. elegans) 3.34771
ASMT acetylserotonin O-methyltransferase 3.34771
SFTPD surfactant protein D 3.34771
STAP1 signal transducing adaptor family member 1 3.34771
PANO1 proapoptotic nucleolar protein 1 3.34771
PCDHGA12 protocadherin gamma subfamily A, 12 3.34771
PRSS21 protease, serine, 21 (testisin) 3.34771
GRM2 glutamate receptor, metabotropic 2 3.34771
MAFA v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog A 3.34771
LKAAEAR1 LKAAEAR motif containing 1 3.34771
APOA5 apolipoprotein A-V 3.34771
NRGN neurogranin (protein kinase C substrate, RC3) 3.34771
GPD1 glycerol-3-phosphate dehydrogenase 1 (soluble) 3.34771
TNFSF4 tumor necrosis factor (ligand) superfamily, member 4 3.34771
SPACA5 sperm acrosome associated 5 3.34771
AIPL1 aryl hydrocarbon receptor interacting protein-like 1 3.34771
ABCG5 ATP-binding cassette, sub-family G (WHITE), member 5 3.34771
BSX brain-specific homeobox 3.34771
LRRC10B leucine rich repeat containing 10B 3.34771
CPB2 carboxypeptidase B2 (plasma) 3.34771
MAGED4 melanoma antigen family D4 3.34771
GNRHR gonadotropin-releasing hormone receptor 3.34771
OXT oxytocin/neurophysin I prepropeptide 3.34771
IL2RB interleukin 2 receptor, beta 3.34771
TRPC5OS TRPC5 opposite strand 3.34771
CPLX3 complexin 3 3.34771
CACNG3 calcium channel, voltage-dependent, gamma subunit 3 3.34771
GJA9 gap junction protein, alpha 9, 59kDa 3.34771
SPMIP9 sperm microtubule inner protein 9 3.34771
GBP6 guanylate binding protein family, member 6 3.34771
ROPN1B rhophilin associated tail protein 1B 3.34771
ST6GALNAC2 ST6 (alpha-N-acetyl-neuraminyl-2,3-beta-galactosyl-1,3)-N-acetylgalactosaminide alpha-2,6-sialyltransferase 2 3.34771
LTB4R2 leukotriene B4 receptor 2 3.34771
ALX4 ALX homeobox 4 3.34771
SMLR1 small leucine-rich protein 1 3.34771
ADRB1 adrenoceptor beta 1 3.34771
XKR3 XK, Kell blood group complex subunit-related family, member 3 3.34771
SPATA22 spermatogenesis associated 22 3.34771
LTB lymphotoxin beta (TNF superfamily, member 3) 3.34771
IRAG2 inositol 1,4,5-triphosphate receptor associated 2 3.34771
PYDC5 pyrin domain containing 5 3.34771
CCN5 cellular communication network factor 5 3.34771
SPATA31H1 SPATA31 subfamily H member 1 3.34771
SPEGNB SPEG neighbor 3.34771
TBC1D3I TBC1 domain family member 3I 3.34771
WASH8P WAS protein family homolog 8, pseudogene 3.34771
H3-7 H3.7 histone (putative) 3.34771
ACP7 acid phosphatase 7, tartrate resistant (putative) 3.34771
TMEM272 transmembrane protein 272 3.34771
TENT5D terminal nucleotidyltransferase 5D 3.34771
VXN vexin 3.34771
CALHM5 calcium homeostasis modulator family member 5 3.34771
ATP2B3 ATPase, Ca++ transporting, plasma membrane 3 3.34771
CCR3 chemokine (C-C motif) receptor 3 3.34771
INSRR insulin receptor-related receptor 3.34771
DMP1 dentin matrix acidic phosphoprotein 1 3.34771
PTPRQ protein tyrosine phosphatase, receptor type, Q 3.34771
PRB2 proline-rich protein BstNI subfamily 2 3.34771
OR5H1 olfactory receptor, family 5, subfamily H, member 1 3.34771
OR2A5 olfactory receptor, family 2, subfamily A, member 5 3.34771
FAM3D family with sequence similarity 3, member D 3.34771
SLC22A11 solute carrier family 22 (organic anion/urate transporter), member 11 3.34771
SYCP2 synaptonemal complex protein 2 3.34771
TAS2R3 taste receptor, type 2, member 3 3.34771
NCBP2L nuclear cap binding protein subunit 2-like 3.34771
PCDHB11 protocadherin beta 11 3.34771
CLDN5 claudin 5 3.34771
EDAR ectodysplasin A receptor 3.34771
C1QL2 complement component 1, q subcomponent-like 2 3.34771
SH3TC1 SH3 domain and tetratricopeptide repeats 1 3.34771
SCIMP SLP adaptor and CSK interacting membrane protein 3.34771
TLR6 toll-like receptor 6 3.34771
ZIC4 Zic family member 4 3.34771
LIX1 Lix1 homolog (chicken) 3.34771
CD48 CD48 molecule 3.34771
MAL mal, T-cell differentiation protein 3.34771
TSGA10IP testis specific, 10 interacting protein 3.34771
ERVFRD-1 endogenous retrovirus group FRD, member 1 3.34771
NDRG1 N-myc downstream regulated 1 3.34771
LOXL4 lysyl oxidase-like 4 3.34771
FNDC8 fibronectin type III domain containing 8 3.34771
CD5L CD5 molecule-like 3.34771
CD53 CD53 molecule 3.34771
MAMLD1 mastermind-like domain containing 1 3.34771
CGB2 chorionic gonadotropin, beta polypeptide 2 3.34771
RSPH10B radial spoke head 10 homolog B (Chlamydomonas) 3.34771
C22ORF42 chromosome 22 open reading frame 42 3.34771
PCDHGA4 protocadherin gamma subfamily A, 4 3.34771
TEKT1 tektin 1 3.34771
TEX19 testis expressed 19 3.34771
ORM2 orosomucoid 2 3.34771
WFDC6 WAP four-disulfide core domain 6 3.34771
MYF6 myogenic factor 6 (herculin) 3.34771
TMEM132E transmembrane protein 132E 3.34771
SLC6A17 solute carrier family 6 (neutral amino acid transporter), member 17 3.34771
THTPA thiamine triphosphatase 3.34771
C11ORF96 chromosome 11 open reading frame 96 3.34771
CTAGE4 CTAGE family, member 4 3.34771
CTAGE9 CTAGE family, member 9 3.34771
GLOD5 glyoxalase domain containing 5 3.34771
LCN8 lipocalin 8 3.34771
PCDH12 protocadherin 12 3.34771
ANKS4B ankyrin repeat and sterile alpha motif domain containing 4B 3.34771
P2RX2 purinergic receptor P2X, ligand gated ion channel, 2 3.34771
SH2D1B SH2 domain containing 1B 3.34771
CYP2D6 cytochrome P450, family 2, subfamily D, polypeptide 6 3.34771
GPR150 G protein-coupled receptor 150 3.34771
KCNA5 potassium channel, voltage gated shaker related subfamily A, member 5 3.34771
KCNA7 potassium channel, voltage gated shaker related subfamily A, member 7 3.34771
HPGDS hematopoietic prostaglandin D synthase 3.34771
LAMB4 laminin, beta 4 3.34771
PLA2G5 phospholipase A2, group V 3.34771
SMPD1 sphingomyelin phosphodiesterase 1, acid lysosomal 3.34771
SLC38A8 solute carrier family 38, member 8 3.34771
SLC6A20 solute carrier family 6 (proline IMINO transporter), member 20 3.34771
PATE4 prostate and testis expressed 4 3.34771
LRRK2 leucine-rich repeat kinase 2 3.34771
C20ORF144 chromosome 20 open reading frame 144 3.34771
LRRC15 leucine rich repeat containing 15 3.34771
SAMD5 sterile alpha motif domain containing 5 3.34771
UTS2R urotensin 2 receptor 3.34771
HLA-DQA2 major histocompatibility complex, class II, DQ alpha 2 3.34771
TH tyrosine hydroxylase 3.34771
DAPL1 death associated protein-like 1 3.34771
GOLGA8R golgin A8 family, member R 3.34771
TSPAN32 tetraspanin 32 3.34771
ZNF534 zinc finger protein 534 3.34771
ERMN ermin, ERM-like protein 3.34771
CROCC2 ciliary rootlet coiled-coil, rootletin family member 2 3.34771
RNF224 ring finger protein 224 3.34771
CYP4Z1 cytochrome P450, family 4, subfamily Z, polypeptide 1 3.34771
PRR15L proline rich 15-like 3.34771
TBC1D28 TBC1 domain family, member 28 3.34771
KIF4B kinesin family member 4B 3.34771
DMTN dematin actin binding protein 3.34771
NPAS4 neuronal PAS domain protein 4 3.34771
PXT1 peroxisomal, testis specific 1 3.34771
MAPK11 mitogen-activated protein kinase 11 3.34771
SLC51B solute carrier family 51, beta subunit 3.34771
CCNO cyclin O 3.34771
PLGLB1 plasminogen-like B1 3.34771
PCDHGB2 protocadherin gamma subfamily B, 2 3.34771
PCDHGB5 protocadherin gamma subfamily B, 5 3.34771
MYOZ2 myozenin 2 3.34771
SERPIND1 serpin peptidase inhibitor, clade D (heparin cofactor), member 1 3.34771
PMP2 peripheral myelin protein 2 3.34771
TAS2R43 taste receptor, type 2, member 43 3.34771
PPP1R3C protein phosphatase 1, regulatory subunit 3C 3.34771
TGM3 transglutaminase 3 3.34771
SLITRK6 SLIT and NTRK-like family, member 6 3.34771
ASCL2 achaete-scute family bHLH transcription factor 2 3.34771
SMIM22 small integral membrane protein 22 3.34771
AP4S1 adaptor-related protein complex 4, sigma 1 subunit 3.29661
ZNF436 zinc finger protein 436 3.22948
TNN tenascin N 3.08294
ERAL1 Era-like 12S mitochondrial rRNA chaperone 1 3.04623
DGCR8 DGCR8 microprocessor complex subunit 2.99813
CASTOR2 cytosolic arginine sensor for mTORC1 subunit 2 2.97297
RMDN3 regulator of microtubule dynamics 3 2.94767
DDX39B DEAD (Asp-Glu-Ala-Asp) box polypeptide 39B 2.87202
THOC6 THO complex 6 2.84423
COPS3 COP9 signalosome subunit 3 2.79803
IFT54 intraflagellar transport 54 2.77118
ZNF540 zinc finger protein 540 2.71149
ITGB1BP1 integrin beta 1 binding protein 1 2.67365
CLTC clathrin, heavy chain (Hc) 2.65966
ZNHIT6 zinc finger, HIT-type containing 6 2.56183
NOVA2 neuro-oncological ventral antigen 2 2.52811
ZNF25 zinc finger protein 25 2.52626
SOX2 SRY (sex determining region Y)-box 2 2.51792
CCDC184 coiled-coil domain containing 184 2.50852
TBX20 T-box 20 2.50606
SRD5A1 steroid-5-alpha-reductase, alpha polypeptide 1 (3-oxo-5 alpha-steroid delta 4-dehydrogenase alpha 1) 2.46034
KANK3 KN motif and ankyrin repeat domains 3 2.43784
IFT70B intraflagellar transport 70B 2.38409
GABRA1 gamma-aminobutyric acid (GABA) A receptor, alpha 1 2.37691
APOOL apolipoprotein O-like 2.35416
AGAP2 ArfGAP with GTPase domain, ankyrin repeat and PH domain 2 2.33921
UNC13B unc-13 homolog B (C. elegans) 2.33025
DYSF dysferlin 2.31565
SH3GL2 SH3-domain GRB2-like 2 2.30371
MAP3K5 mitogen-activated protein kinase kinase kinase 5 2.30348
ACRV1 acrosomal vesicle protein 1 2.30229
KIF3C kinesin family member 3C 2.26213
FXYD2 FXYD domain containing ion transport regulator 2 2.25897
RNFT2 ring finger protein, transmembrane 2 2.25897
INCA1 inhibitor of CDK, cyclin A1 interacting protein 1 2.25897
TNNC2 troponin C type 2 (fast) 2.25897
GUSB glucuronidase, beta 2.2498
GPR20 G protein-coupled receptor 20 2.23431
VEGFD vascular endothelial growth factor D 2.23431
ADAM12 ADAM metallopeptidase domain 12 2.23431
SHBG sex hormone-binding globulin 2.23431
ZSCAN22 zinc finger and SCAN domain containing 22 2.23431
TUBA3D tubulin, alpha 3d 2.23431
KLHDC8A kelch domain containing 8A 2.23431
MFSD6L major facilitator superfamily domain containing 6-like 2.23431
FGF13 fibroblast growth factor 13 2.22769
SELENOV selenoprotein V 2.22065
H2BC15 H2B clustered histone 15 2.21605
JUND jun D proto-oncogene 2.19063
UFD1 ubiquitin recognition factor in ER associated degradation 1 2.1873
AVPI1 arginine vasopressin-induced 1 2.14958
LRP11 low density lipoprotein receptor-related protein 11 2.14664
RMND1 required for meiotic nuclear division 1 homolog (S. cerevisiae) 2.14344
ADGRL1 adhesion G protein-coupled receptor L1 2.13505
SLC45A1 solute carrier family 45, member 1 2.12461
MZT2B mitotic spindle organizing protein 2B 2.12461
MTCL1 microtubule crosslinking factor 1 2.11165
TBC1D30 TBC1 domain family, member 30 2.10479
C3ORF62 chromosome 3 open reading frame 62 2.0594
UBE2L6 ubiquitin-conjugating enzyme E2L 6 2.02896
C21ORF91 chromosome 21 open reading frame 91 2.02472
OCIAD1 OCIA domain containing 1 2.00343
DDRGK1 DDRGK domain containing 1 2.00302

decreased expression

Symbol Name Standardized Value
C17ORF78 chromosome 17 open reading frame 78 -3.34771
MBOAT4 membrane bound O-acyltransferase domain containing 4 -3.34771
ECEL1 endothelin converting enzyme-like 1 -3.34771
SPTBN5 spectrin, beta, non-erythrocytic 5 -3.34771
FRZB frizzled-related protein -3.34771
C6ORF163 chromosome 6 open reading frame 163 -3.34771
HES4 hes family bHLH transcription factor 4 -3.34771
PON3 paraoxonase 3 -3.34771
KCNF1 potassium channel, voltage gated modifier subfamily F, member 1 -3.34771
ZMYND12 zinc finger, MYND-type containing 12 -3.34771
KCNJ9 potassium channel, inwardly rectifying subfamily J, member 9 -3.34771
DNAH8 dynein, axonemal, heavy chain 8 -3.34771
IFI6 interferon, alpha-inducible protein 6 -3.34771
GPRC5A G protein-coupled receptor, class C, group 5, member A -3.34771
APOL6 apolipoprotein L, 6 -3.34771
LYNX1 Ly6/neurotoxin 1 -3.34771
CBFA2T3 core-binding factor, runt domain, alpha subunit 2; translocated to, 3 -3.34771
NOL3 nucleolar protein 3 (apoptosis repressor with CARD domain) -3.34771
DAND5 DAN domain family member 5, BMP antagonist -3.34771
CD1D CD1d molecule -3.34771
CHRND cholinergic receptor, nicotinic, delta (muscle) -3.34771
PIRT phosphoinositide-interacting regulator of transient receptor potential channels -3.34771
LRRN4 leucine rich repeat neuronal 4 -3.34771
ADCY4 adenylate cyclase 4 -3.34771
TSPAN16 tetraspanin 16 -3.34771
MEOX2 mesenchyme homeobox 2 -3.34771
PCDHA1 protocadherin alpha 1 -3.34771
SLC17A6 solute carrier family 17 (vesicular glutamate transporter), member 6 -3.34771
ANKRD53 ankyrin repeat domain 53 -3.34771
LOC122539214 Zinc finger protein LOC122539214 -3.34771
PLPP4 phospholipid phosphatase 4 -3.34771
NPAP1 nuclear pore associated protein 1 -3.34771
DXO decapping exoribonuclease -3.34771
GGTA1 glycoprotein alpha-galactosyltransferase 1 (inactive) -3.34771
FGF23 fibroblast growth factor 23 -3.34771
C17ORF113 chromosome 17 open reading frame 113 -3.34771
SEMA4F sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4F -3.30365
PATL1 protein associated with topoisomerase II homolog 1 (yeast) -3.29661
MAPK15 mitogen-activated protein kinase 15 -3.24605
TEFM transcription elongation factor, mitochondrial -3.20798
SP1 Sp1 transcription factor -3.16114
SLF1 SMC5-SMC6 complex localization factor 1 -3.03207
NBPF8 neuroblastoma breakpoint family, member 8 -2.87111
GLG1 golgi glycoprotein 1 -2.84423
TNNT2 troponin T type 2 (cardiac) -2.79265
C5ORF63 chromosome 5 open reading frame 63 -2.74498
CHRM2 cholinergic receptor, muscarinic 2 -2.72269
LRRIQ1 leucine-rich repeats and IQ motif containing 1 -2.72269
DCP1B decapping mRNA 1B -2.67365
CTNNBIP1 catenin, beta interacting protein 1 -2.67351
KATNBL1 katanin p80 subunit B-like 1 -2.6012
RRAS related RAS viral (r-ras) oncogene homolog -2.54857
PIK3C3 phosphatidylinositol 3-kinase, catalytic subunit type 3 -2.53432
RSPH9 radial spoke head 9 homolog (Chlamydomonas) -2.51792
MRPS16 mitochondrial ribosomal protein S16 -2.51792
IGSF22 immunoglobulin superfamily, member 22 -2.51792
TBL3 transducin (beta)-like 3 -2.46133
SRRD SRR1 domain containing -2.45437
KLHDC2 kelch domain containing 2 -2.43784
USP31 ubiquitin specific peptidase 31 -2.43023
ATOSB atos homolog B -2.41167
NIBAN1 niban apoptosis regulator 1 -2.35247
GYS1 glycogen synthase 1 (muscle) -2.35247
KCNH2 potassium channel, voltage gated eag related subfamily H, member 2 -2.35211
SBF2 SET binding factor 2 -2.33921
ZCCHC14 zinc finger, CCHC domain containing 14 -2.33921
MCM5 minichromosome maintenance complex component 5 -2.33025
ID3 inhibitor of DNA binding 3, dominant negative helix-loop-helix protein -2.32406
GAS7 growth arrest-specific 7 -2.27818
SOX12 SRY (sex determining region Y)-box 12 -2.27312
EMILIN1 elastin microfibril interfacer 1 -2.26668
ALOX12B arachidonate 12-lipoxygenase, 12R type -2.26668
TXLNB taxilin beta -2.26668
NPPC natriuretic peptide C -2.26668
TRIM72 tripartite motif containing 72, E3 ubiquitin protein ligase -2.26668
CPEB1 cytoplasmic polyadenylation element binding protein 1 -2.26213
SNX31 sorting nexin 31 -2.25976
GSDMA gasdermin A -2.25976
DLAT dihydrolipoamide S-acetyltransferase -2.25976
DNAH5 dynein, axonemal, heavy chain 5 -2.25804
BTBD1 BTB (POZ) domain containing 1 -2.24199
BAG6 BCL2-associated athanogene 6 -2.23431
A2M alpha-2-macroglobulin -2.23431
HPCAL1 hippocalcin-like 1 -2.23329
CACNB1 calcium channel, voltage-dependent, beta 1 subunit -2.22717
FHIP2B FHF complex subunit HOOK interacting protein 2B -2.22065
HOOK2 hook microtubule-tethering protein 2 -2.20451
FLT3LG fms-related tyrosine kinase 3 ligand -2.17353
JPH2 junctophilin 2 -2.17034
PRSS48 protease, serine, 48 -2.15915
CR1 complement component (3b/4b) receptor 1 (Knops blood group) -2.14958
TMBIM4 transmembrane BAX inhibitor motif containing 4 -2.14344
RREB1 ras responsive element binding protein 1 -2.12461
SEC61G Sec61 gamma subunit -2.10279
LSM8 LSM8 homolog, U6 small nuclear RNA associated (S. cerevisiae) -2.07038
ISYNA1 inositol-3-phosphate synthase 1 -2.06635
RALGPS1 Ral GEF with PH domain and SH3 binding motif 1 -2.06393
PCTP phosphatidylcholine transfer protein -2.04589
E2F4 E2F transcription factor 4, p107/p130-binding -2.03595
LPAR1 lysophosphatidic acid receptor 1 -2.02434
RANGAP1 Ran GTPase activating protein 1 -2.01335
AXIN2 axin 2 -2.00678
PNMA6A paraneoplastic Ma antigen family member 6A -2.00343
STUB1 STIP1 homology and U-box containing protein 1, E3 ubiquitin protein ligase -2.00343
PPP3R1 protein phosphatase 3, regulatory subunit B, alpha -2.00343
H3-3B H3.3 histone B -2.00302
PPIL4 peptidylprolyl isomerase (cyclophilin)-like 4 -2.00302
EMG1 EMG1 N1-specific pseudouridine methyltransferase -2.00302