SGK1 Gene Set

Dataset Kinase Library Serine Threonine Kinome Atlas
Category proteomics
Type kinase
Description serum/glucocorticoid regulated kinase 1|This gene encodes a serine/threonine protein kinase that plays an important role in cellular stress response. This kinase activates certain potassium, sodium, and chloride channels, suggesting an involvement in the regulation of processes such as cell survival, neuronal excitability, and renal sodium excretion. High levels of expression of this gene may contribute to conditions such as hypertension and diabetic nephropathy. Several alternatively spliced transcript variants encoding different isoforms have been noted for this gene. [provided by RefSeq, Jan 2009] (NCBI Entrez Gene Database, 6446)
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100 substrates of the kinase SGK1 from the Kinase Library Serine Threonine Kinome Atlas dataset.

Symbol Name Standardized Value
UBE2O ubiquitin-conjugating enzyme E2O
TTN titin
PPP1R1A protein phosphatase 1, regulatory (inhibitor) subunit 1A
PPP1R1C protein phosphatase 1, regulatory (inhibitor) subunit 1C
PPP1R1B protein phosphatase 1, regulatory (inhibitor) subunit 1B
IER2 immediate early response 2
TP53RK TP53 regulating kinase
TRIM17 tripartite motif containing 17
BTK Bruton agammaglobulinemia tyrosine kinase
C11ORF30 chromosome 11 open reading frame 30
HEATR3 HEAT repeat containing 3
KMT2A lysine (K)-specific methyltransferase 2A
APTX aprataxin
WNK1 WNK lysine deficient protein kinase 1
BRCA1 breast cancer 1, early onset
KIF27 kinesin family member 27
KIF23 kinesin family member 23
EHBP1L1 EH domain binding protein 1-like 1
MKI67 marker of proliferation Ki-67
PDE3A phosphodiesterase 3A, cGMP-inhibited
PDE3B phosphodiesterase 3B, cGMP-inhibited
SCAF1 SR-related CTD-associated factor 1
PLXNB1 plexin B1
ARHGAP11A Rho GTPase activating protein 11A
CTR9 CTR9, Paf1/RNA polymerase II complex component
AKAP12 A kinase (PRKA) anchor protein 12
ALKBH5 AlkB family member 5, RNA demethylase
THOC5 THO complex 5
PBRM1 polybromo 1
CDC42BPA CDC42 binding protein kinase alpha (DMPK-like)
FRMD4B FERM domain containing 4B
VASP vasodilator-stimulated phosphoprotein
RPS6 ribosomal protein S6
JADE2 jade family PHD finger 2
PHF14 PHD finger protein 14
CEP170B centrosomal protein 170B
PRRT3 proline-rich transmembrane protein 3
CREBZF CREB/ATF bZIP transcription factor
DMXL1 Dmx-like 1
MYO3A myosin IIIA
BAHD1 bromo adjacent homology domain containing 1
TRPS1 trichorhinophalangeal syndrome I
MVD mevalonate (diphospho) decarboxylase
SRSF2 serine/arginine-rich splicing factor 2
PIGB phosphatidylinositol glycan anchor biosynthesis, class B
ATR ATR serine/threonine kinase
RBM34 RNA binding motif protein 34
DEPDC5 DEP domain containing 5
S1PR1 sphingosine-1-phosphate receptor 1
SLC8B1 solute carrier family 8 (sodium/lithium/calcium exchanger), member B1
RAPGEF6 Rap guanine nucleotide exchange factor (GEF) 6
RARA retinoic acid receptor, alpha
SUPT16H suppressor of Ty 16 homolog (S. cerevisiae)
HBP1 HMG-box transcription factor 1
GRK7 G protein-coupled receptor kinase 7
GPR15 G protein-coupled receptor 15
ARNTL aryl hydrocarbon receptor nuclear translocator-like
MAP3K11 mitogen-activated protein kinase kinase kinase 11
RARG retinoic acid receptor, gamma
SECISBP2L SECIS binding protein 2-like
CDR2L cerebellar degeneration-related protein 2-like
URI1 URI1, prefoldin-like chaperone
ANKRD33B ankyrin repeat domain 33B
GON4L gon-4-like (C. elegans)
RAPGEF2 Rap guanine nucleotide exchange factor (GEF) 2
CEP128 centrosomal protein 128kDa
SMARCC1 SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily c, member 1
PYGO2 pygopus family PHD finger 2
CDCA2 cell division cycle associated 2
CDCA7 cell division cycle associated 7
ZFP91 ZFP91 zinc finger protein
CHKB choline kinase beta
DSP desmoplakin
KCNN2 potassium channel, calcium activated intermediate/small conductance subfamily N alpha, member 2
FAM214B family with sequence similarity 214, member B
PKD2 polycystic kidney disease 2 (autosomal dominant)
PPIP5K2 diphosphoinositol pentakisphosphate kinase 2
ZFC3H1 zinc finger, C3H1-type containing
NELFA negative elongation factor complex member A
TWIST1 twist family bHLH transcription factor 1
PFKFB2 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 2
SETD2 SET domain containing 2
INTS3 integrator complex subunit 3
REM2 RAS (RAD and GEM)-like GTP binding 2
LARP4B La ribonucleoprotein domain family, member 4B
RASSF1 Ras association (RalGDS/AF-6) domain family member 1
FAM207A family with sequence similarity 207, member A
EI24 etoposide induced 2.4
SETD1A SET domain containing 1A
KIF4A kinesin family member 4A
KANK1 KN motif and ankyrin repeat domains 1
ASH1L ash1 (absent, small, or homeotic)-like (Drosophila)
SUN2 Sad1 and UNC84 domain containing 2
ZNF212 zinc finger protein 212
KCNJ16 potassium channel, inwardly rectifying subfamily J, member 16
KCNH2 potassium channel, voltage gated eag related subfamily H, member 2
UBR5 ubiquitin protein ligase E3 component n-recognin 5
POU5F1 POU class 5 homeobox 1
PPP1R12A protein phosphatase 1, regulatory subunit 12A
TBC1D4 TBC1 domain family, member 4