SGO2 Gene Set

Dataset CM4AI KOLF21J CRISPRi Gene Perturbation Atlas
Category transcriptomics
Type gene perturbation
Description shugoshin 2 (NCBI Entrez Gene Database, 151246)
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Genes

310 genes differentially expressed following the SGO2 gene perturbation from the CM4AI KOLF21J CRISPRi Gene Perturbation Atlas.

increased expression

Symbol Name Standardized Value
NR1I2 nuclear receptor subfamily 1, group I, member 2 2.85749
ADAMTSL2 ADAMTS-like 2 2.85749
CISH cytokine inducible SH2-containing protein 2.85749
RIN1 Ras and Rab interactor 1 2.85749
SLC12A5 solute carrier family 12 (potassium/chloride transporter), member 5 2.85749
BTNL9 butyrophilin-like 9 2.85749
TMEM176A transmembrane protein 176A 2.85749
C11ORF86 chromosome 11 open reading frame 86 2.85749
MCHR1 melanin-concentrating hormone receptor 1 2.83122
PTCRA pre T-cell antigen receptor alpha 2.83122
S100A14 S100 calcium binding protein A14 2.83122
MAOB monoamine oxidase B 2.83122
ENPP6 ectonucleotide pyrophosphatase/phosphodiesterase 6 2.83122
TEX12 testis expressed 12 2.83122
KCNJ9 potassium channel, inwardly rectifying subfamily J, member 9 2.83122
C1ORF146 chromosome 1 open reading frame 146 2.83122
CDNF cerebral dopamine neurotrophic factor 2.83122
FPR3 formyl peptide receptor 3 2.83122
LRRC8C-DT LRRC8C divergent transcript 2.83122
VSIG1 V-set and immunoglobulin domain containing 1 2.83122
ARL11 ADP-ribosylation factor-like 11 2.83122
ADGRB1 adhesion G protein-coupled receptor B1 2.83122
PSMB7 proteasome (prosome, macropain) subunit, beta type, 7 2.8218
BTN1A1 butyrophilin, subfamily 1, member A1 2.80324
CTRC chymotrypsin C (caldecrin) 2.80324
MPEG1 macrophage expressed 1 2.80324
SPDYE6 speedy/RINGO cell cycle regulator family member E6 2.80324
TAS2R31 taste receptor, type 2, member 31 2.80324
SLC22A16 solute carrier family 22 (organic cation/carnitine transporter), member 16 2.80324
MAMSTR MEF2 activating motif and SAP domain containing transcriptional regulator 2.80324
GJA5 gap junction protein, alpha 5, 40kDa 2.80324
HRH4 histamine receptor H4 2.80324
COL20A1 collagen, type XX, alpha 1 2.80324
SPSB3 splA/ryanodine receptor domain and SOCS box containing 3 2.80324
NPAP1 nuclear pore associated protein 1 2.80324
SPINK4 serine peptidase inhibitor, Kazal type 4 2.80324
CEP295NL CEP295 N-terminal like 2.80324
MUC1 mucin 1, cell surface associated 2.80324
NRROS negative regulator of reactive oxygen species 2.80324
LRRC10B leucine rich repeat containing 10B 2.80324
SLC28A2 solute carrier family 28 (concentrative nucleoside transporter), member 2 2.80324
OC90 otoconin 90 2.80324
SLC2A2 solute carrier family 2 (facilitated glucose transporter), member 2 2.80324
NCCRP1 non-specific cytotoxic cell receptor protein 1 homolog (zebrafish) 2.80324
CRYGS crystallin, gamma S 2.80324
SPHK1 sphingosine kinase 1 2.80324
SLC9C2 solute carrier family 9, member C2 (putative) 2.80324
DCAF4L1 DDB1 and CUL4 associated factor 4-like 1 2.80324
ADAD2 adenosine deaminase domain containing 2 2.80324
MRPL53 mitochondrial ribosomal protein L53 2.80324
ZBTB42 zinc finger and BTB domain containing 42 2.80324
PROB1 proline-rich basic protein 1 2.80324
LONRF3 LON peptidase N-terminal domain and ring finger 3 2.80324
GJB5 gap junction protein, beta 5, 31.1kDa 2.80324
BMP8B bone morphogenetic protein 8b 2.80324
GFAP glial fibrillary acidic protein 2.80324
GDNF glial cell derived neurotrophic factor 2.80324
HBEGF heparin-binding EGF-like growth factor 2.80324
ACTL10 actin-like 10 2.80324
CSNK2A2IP casein kinase 2 subunit alpha' interacting protein 2.80324
DDC dopa decarboxylase (aromatic L-amino acid decarboxylase) 2.80324
GBP5 guanylate binding protein 5 2.80324
GBP3 guanylate binding protein 3 2.80324
CLDN14 claudin 14 2.80324
HTRA4 HtrA serine peptidase 4 2.80324
SEMA4F sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4F 2.80324
SRGN serglycin 2.80324
SLC2A6 solute carrier family 2 (facilitated glucose transporter), member 6 2.80324
ANO3 anoctamin 3 2.80324
IRAG2 inositol 1,4,5-triphosphate receptor associated 2 2.80324
ARSL arylsulfatase L 2.80324
LOC114841035 uncharacterized LOC114841035 2.80324
LY6S lymphocyte antigen 6 family member S 2.80324
SMIM47 small integral membrane protein 47 2.80324
GLYATL1B glycine-N-acyltransferase like 1B 2.80324
DEFB131B defensin beta 131B 2.80324
H2BC3 H2B clustered histone 3 2.80324
CCDC163 CCDC163 homolog 2.80324
ATP5MC2 ATP synthase membrane subunit c locus 2 2.80324
NSG2 neuronal vesicle trafficking associated 2 2.80324
CMKLR1 chemerin chemokine-like receptor 1 2.80324
LTK leukocyte receptor tyrosine kinase 2.80324
SOAT2 sterol O-acyltransferase 2 2.80324
CBLN1 cerebellin 1 precursor 2.80324
ZSWIM2 zinc finger, SWIM-type containing 2 2.80324
CCR6 chemokine (C-C motif) receptor 6 2.80324
CHRD chordin 2.80324
LCAT lecithin-cholesterol acyltransferase 2.80324
CCDC13 coiled-coil domain containing 13 2.80324
PCDHB10 protocadherin beta 10 2.80324
GGT6 gamma-glutamyltransferase 6 2.80324
PCDHA7 protocadherin alpha 7 2.80324
CATSPERD catsper channel auxiliary subunit delta 2.80324
SCRT2 scratch family zinc finger 2 2.80324
PXDC1 PX domain containing 1 2.80324
NOXA1 NADPH oxidase activator 1 2.80324
FAM131C family with sequence similarity 131, member C 2.80324
OR10K1 olfactory receptor, family 10, subfamily K, member 1 2.80324
GLIPR1L2 GLI pathogenesis-related 1 like 2 2.80324
CCR9 chemokine (C-C motif) receptor 9 2.80324
EXOC3L1 exocyst complex component 3-like 1 2.80324
MYOT myotilin 2.80324
CREB3L3 cAMP responsive element binding protein 3-like 3 2.80324
CAPN14 calpain 14 2.80324
TMEM150B transmembrane protein 150B 2.80324
EFCAB3 EF-hand calcium binding domain 3 2.80324
GPR12 G protein-coupled receptor 12 2.80324
TNR tenascin R 2.80324
KLHL6 kelch-like family member 6 2.80324
FAM50B family with sequence similarity 50, member B 2.80324
DPRX divergent-paired related homeobox 2.80324
GOLGA6B golgin A6 family, member B 2.80324
CD53 CD53 molecule 2.80324
HSD17B1 hydroxysteroid (17-beta) dehydrogenase 1 2.80324
NOG noggin 2.80324
MRGPRE MAS-related GPR, member E 2.80324
ARHGAP20 Rho GTPase activating protein 20 2.80324
KRT17 keratin 17, type I 2.80324
CPM carboxypeptidase M 2.80324
DES desmin 2.80324
C17ORF107 chromosome 17 open reading frame 107 2.80324
APOB apolipoprotein B 2.80324
PCDHGB1 protocadherin gamma subfamily B, 1 2.80324
TMEM132E transmembrane protein 132E 2.80324
GNA15 guanine nucleotide binding protein (G protein), alpha 15 (Gq class) 2.80324
KCNK3 potassium channel, two pore domain subfamily K, member 3 2.80324
FOXE3 forkhead box E3 2.80324
LMOD2 leiomodin 2 (cardiac) 2.80324
RBBP8NL RBBP8 N-terminal like 2.80324
GPR150 G protein-coupled receptor 150 2.80324
GJB6 gap junction protein, beta 6, 30kDa 2.80324
LAMB4 laminin, beta 4 2.80324
PPP1R27 protein phosphatase 1, regulatory subunit 27 2.80324
CLEC18A C-type lectin domain family 18, member A 2.80324
PLA2G5 phospholipase A2, group V 2.80324
ZNF831 zinc finger protein 831 2.80324
VMO1 vitelline membrane outer layer 1 homolog (chicken) 2.80324
UBXN10 UBX domain protein 10 2.80324
TMEM31 transmembrane protein 31 2.80324
SYNGR4 synaptogyrin 4 2.80324
LYL1 lymphoblastic leukemia associated hematopoiesis regulator 1 2.80324
TEKT1 tektin 1 2.80324
RGCC regulator of cell cycle 2.80324
P2RX1 purinergic receptor P2X, ligand gated ion channel, 1 2.80324
KLK6 kallikrein-related peptidase 6 2.80324
KLK4 kallikrein-related peptidase 4 2.80324
ASTL astacin-like metallo-endopeptidase (M12 family) 2.80324
LY96 lymphocyte antigen 96 2.80324
CD200R1 CD200 receptor 1 2.80324
EIF4E1B eukaryotic translation initiation factor 4E family member 1B 2.80324
VWC2L von Willebrand factor C domain containing protein 2-like 2.80324
GRAPL GRB2-related adaptor protein-like 2.80324
GRAP2 GRB2-related adaptor protein 2 2.80324
MAPK8IP2 mitogen-activated protein kinase 8 interacting protein 2 2.80324
MUC21 mucin 21, cell surface associated 2.80324
ASAH2 N-acylsphingosine amidohydrolase (non-lysosomal ceramidase) 2 2.80324
APOL1 apolipoprotein L, 1 2.80324
APOL5 apolipoprotein L, 5 2.80324
APOL6 apolipoprotein L, 6 2.80324
TGM6 transglutaminase 6 2.80324
PPP1R3G protein phosphatase 1, regulatory subunit 3G 2.80324
SLC22A9 solute carrier family 22 (organic anion transporter), member 9 2.80324
SMCO2 single-pass membrane protein with coiled-coil domains 2 2.80324
MMRN1 multimerin 1 2.80324
PRG2 proteoglycan 2, bone marrow (natural killer cell activator, eosinophil granule major basic protein) 2.80324
VPREB3 pre-B lymphocyte 3 2.80324
ZBBX zinc finger, B-box domain containing 2.80324
SEZ6L seizure related 6 homolog (mouse)-like 2.80324
LANCL3 LanC lantibiotic synthetase component C-like 3 (bacterial) 2.80324
POTEI POTE ankyrin domain family, member I 2.80324
DAND5 DAN domain family member 5, BMP antagonist 2.80324
AMER3 APC membrane recruitment protein 3 2.80324
CAMK1G calcium/calmodulin-dependent protein kinase IG 2.80324
ANKRD33 ankyrin repeat domain 33 2.80324
ECM1 extracellular matrix protein 1 2.80324
ITLN2 intelectin 2 2.80324
ACKR3 atypical chemokine receptor 3 2.80324
TMIGD2 transmembrane and immunoglobulin domain containing 2 2.80324
SHOX short stature homeobox 2.80324
AGO2 argonaute RISC catalytic component 2 2.78724
MIPOL1 mirror-image polydactyly 1 2.73499
ACTG2 actin, gamma 2, smooth muscle, enteric 2.72656
SAP18 Sin3A-associated protein, 18kDa 2.61087
DCLRE1A DNA cross-link repair 1A 2.59046
FAM194C family with sequence similarity 149 member C 2.58461
SMIM24 small integral membrane protein 24 2.58461
CNOT1 CCR4-NOT transcription complex, subunit 1 2.57903
SLC27A5 solute carrier family 27 (fatty acid transporter), member 5 2.45206
TOX2 TOX high mobility group box family member 2 2.446
TCEAL1 transcription elongation factor A (SII)-like 1 2.43464
HMGCLL1 3-hydroxymethyl-3-methylglutaryl-CoA lyase-like 1 2.43231
GPR161 G protein-coupled receptor 161 2.43231
TST thiosulfate sulfurtransferase (rhodanese) 2.43031
GABRA2 gamma-aminobutyric acid (GABA) A receptor, alpha 2 2.35319
PIK3C2G phosphatidylinositol-4-phosphate 3-kinase, catalytic subunit type 2 gamma 2.35319
TAFA3 TAFA chemokine like family member 3 2.35319
CCDC194 coiled-coil domain containing 194 2.34887
PEX12 peroxisomal biogenesis factor 12 2.34887
ITIH6 inter-alpha-trypsin inhibitor heavy chain family, member 6 2.34887
METTL16 methyltransferase like 16 2.34887
ZNF418 zinc finger protein 418 2.34212
SELENOK selenoprotein K 2.32567
CBX3 chromobox homolog 3 2.3172
B4GALT3 UDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 3 2.31291
FGF16 fibroblast growth factor 16 2.2853
MLYCD malonyl-CoA decarboxylase 2.27832
KLHL5 kelch-like family member 5 2.27832
SEPHS2 selenophosphate synthetase 2 2.27464
FHIP2B FHF complex subunit HOOK interacting protein 2B 2.26773
MARCHF1 membrane associated ring-CH-type finger 1 2.21179
PDE4A phosphodiesterase 4A, cAMP-specific 2.18658
CLDN7 claudin 7 2.14327
ZNF90 zinc finger protein 90 2.12065
CRELD2 cysteine-rich with EGF-like domains 2 2.11605
HACD2 3-hydroxyacyl-CoA dehydratase 2 2.11422
AKR1B1 aldo-keto reductase family 1, member B1 (aldose reductase) 2.10112
MCM8 minichromosome maintenance complex component 8 2.08848
ERICH1 glutamate-rich 1 2.08706
FYCO1 FYVE and coiled-coil domain containing 1 2.07522
MCMBP minichromosome maintenance complex binding protein 2.01904
TRIM33 tripartite motif containing 33 2.00973

decreased expression

Symbol Name Standardized Value
KCNE5 potassium channel, voltage gated subfamily E regulatory beta subunit 5 -2.83122
POU2F3 POU class 2 homeobox 3 -2.83122
SV2C synaptic vesicle glycoprotein 2C -2.83122
PLP2 proteolipid protein 2 (colonic epithelium-enriched) -2.80324
CRIP1 cysteine-rich protein 1 (intestinal) -2.80324
STARD3 StAR-related lipid transfer (START) domain containing 3 -2.80324
CSF1 colony stimulating factor 1 (macrophage) -2.80324
NUDT9 nudix (nucleoside diphosphate linked moiety X)-type motif 9 -2.80324
ZNF154 zinc finger protein 154 -2.80324
DNAAF3 dynein, axonemal, assembly factor 3 -2.80324
XKRX XK, Kell blood group complex subunit-related, X-linked -2.80324
METTL24 methyltransferase like 24 -2.80324
TOR4A torsin family 4, member A -2.80324
GLRA3 glycine receptor, alpha 3 -2.80324
SLC26A6 solute carrier family 26 (anion exchanger), member 6 -2.80324
SLX4 SLX4 structure-specific endonuclease subunit -2.80324
AKR1C3 aldo-keto reductase family 1, member C3 -2.80324
WNT3A wingless-type MMTV integration site family, member 3A -2.80324
TBX19 T-box 19 -2.80324
TGFBR3 transforming growth factor, beta receptor III -2.80324
OR10A2 olfactory receptor, family 10, subfamily A, member 2 -2.80324
SYCP3 synaptonemal complex protein 3 -2.80324
CYP3A7 cytochrome P450, family 3, subfamily A, polypeptide 7 -2.80324
RPH3AL rabphilin 3A-like (without C2 domains) -2.80324
C9ORF153 chromosome 9 open reading frame 153 -2.80324
RAB36 RAB36, member RAS oncogene family -2.80324
PLXND1 plexin D1 -2.80324
CFAP141 cilia and flagella associated protein 141 -2.80324
SSC5D scavenger receptor cysteine rich family, 5 domains -2.80324
SPMIP3 sperm microtubule inner protein 3 -2.80324
GLRB glycine receptor, beta -2.80324
KIFC2 kinesin family member C2 -2.80324
INSYN2B inhibitory synaptic factor family member 2B -2.80324
PNMA8C PNMA family member 8C -2.80324
TMEM255A transmembrane protein 255A -2.80324
MZB1 marginal zone B and B1 cell-specific protein -2.80324
GTF2A1L general transcription factor IIA, 1-like -2.80324
TMEM61 transmembrane protein 61 -2.80324
JAKMIP3 Janus kinase and microtubule interacting protein 3 -2.80324
ENKUR enkurin, TRPC channel interacting protein -2.80324
ARMC5 armadillo repeat containing 5 -2.80324
MST1 macrophage stimulating 1 -2.80324
SGO2 shugoshin 2 -2.80324
DGCR6 DiGeorge syndrome critical region gene 6 -2.80324
DPP7 dipeptidyl-peptidase 7 -2.80324
DUSP1 dual specificity phosphatase 1 -2.80192
ZBTB32 zinc finger and BTB domain containing 32 -2.74443
CAPN6 calpain 6 -2.68585
OTULIN OTU deubiquitinase with linear linkage specificity -2.6456
RRAGD Ras-related GTP binding D -2.6456
NDUFAF8 NADH:ubiquinone oxidoreductase complex assembly factor 8 -2.62906
CPLX2 complexin 2 -2.58461
TUBB4A tubulin, beta 4A class IVa -2.53523
ARHGAP45 Rho GTPase activating protein 45 -2.50011
ASGR1 asialoglycoprotein receptor 1 -2.47872
UBE2V2 ubiquitin-conjugating enzyme E2 variant 2 -2.40496
ERICH5 glutamate-rich 5 -2.37546
HIST1H2BF histone cluster 1, H2bf -2.37546
ZCCHC9 zinc finger, CCHC domain containing 9 -2.37546
ANXA6 annexin A6 -2.36982
ODAD3 outer dynein arm docking complex subunit 3 -2.35319
AP3B2 adaptor-related protein complex 3, beta 2 subunit -2.34887
SEC24A SEC24 family member A -2.31299
HASPIN histone H3 associated protein kinase -2.30101
EFHC2 EF-hand domain (C-terminal) containing 2 -2.28231
MGLL monoglyceride lipase -2.28231
DSTYK dual serine/threonine and tyrosine protein kinase -2.27832
CFAP210 cilia and flagella associated protein 210 -2.27488
LRRIQ1 leucine-rich repeats and IQ motif containing 1 -2.26773
ICE2 interactor of little elongation complex ELL subunit 2 -2.26773
TXNIP thioredoxin interacting protein -2.26525
ZNF25 zinc finger protein 25 -2.26154
GOT1 glutamic-oxaloacetic transaminase 1, soluble -2.2394
CALCRL calcitonin receptor-like -2.22605
SEC14L2 SEC14-like 2 (S. cerevisiae) -2.21945
GPR160 G protein-coupled receptor 160 -2.16783
NT5E 5'-nucleotidase, ecto (CD73) -2.14503
GEMIN7 gem (nuclear organelle) associated protein 7 -2.11605
PPARA peroxisome proliferator-activated receptor alpha -2.11191
SAMD4A sterile alpha motif domain containing 4A -2.10953
NPC1 Niemann-Pick disease, type C1 -2.10215
SPATA6L spermatogenesis associated 6-like -2.0943
VPS45 vacuolar protein sorting 45 homolog (S. cerevisiae) -2.08848
GNG5 guanine nucleotide binding protein (G protein), gamma 5 -2.07776
BCORL1 BCL6 corepressor-like 1 -2.06521
THRB thyroid hormone receptor, beta -2.05998
CLDN12 claudin 12 -2.04318
POU5F1B POU class 5 homeobox 1B -2.04257
PALM paralemmin -2.00212